Researchers are enrolling 500 participants, 400 with primary/secondary immune system disorders and 100 without, to study COVID-19 vaccine responses. The study aims to characterize features and adequacy of immune responses and provide valuable information about benefits and potential risks in individuals with immune deficiencies.
A study of 2.4 million hospitalised cannabis users found that those with an arrhythmia were 4.5 times more likely to die in hospital than those without. Patients with arrhythmias also had longer hospital stays and more co-existing health conditions.
Active learning is used to identify promising organic molecules for efficient solar cells by iteratively deciding which data to learn from. This approach allows the algorithm to efficiently explore a vast molecular space and continuously improve its performance.
Scientists at Texas A&M University designed a new type of battery that eliminates the need for metals and flammable electrolytes. The metal-free, water-based battery shows improved energy storage performance despite lower capacity compared to traditional Li-ion batteries.
Researchers have developed a cloud-based platform called ZeroCostDL4Mic that uses artificial intelligence to analyze microscopy images, improving image quality and detecting features such as tumors in biopsy samples. The platform is freely available online and requires no coding expertise, making it accessible to non-experts.
A clinical trial of 240 patients with moderate to severe COVID-19 found that a high dose of vitamin D3 had no impact on length of stay or risk of ICU admission and death. The researchers suggest that continuous use of vitamin D may have beneficial effects for certain individuals, but more research is needed.
A Phase IIb trial of a candidate malaria vaccine, R21/Matrix-M, demonstrated high-level efficacy of 77% over 12 months. The vaccine has been well-tolerated and is the first to meet the World Health Organization's goal of a vaccine with at least 75% efficacy.
Professor Amro M. Farid, a Dartmouth associate professor, has been awarded the 2021 Fulbright Future Scholar award in Australia. He will work on the 'Architecting Australia's Nexus Infrastructure of Energy, Water & Hydrogen' project to contribute to the country's national hydrogen strategy.
New research suggests that capping US Superfund sites with soil to lock in asbestos may increase human exposure to the cancer-causing mineral. Lab experiments found that soil's organic material enables asbestos to move through the ground and potentially into nearby water supplies.
Researchers identified a set of approaches to assess human-automation teams' communication, focusing on structure, emotion, and content. The 11-critical approaches aim to improve Soldier-robot interactions, enabling less manual input and more natural teamworking.
Astronomers capture breathtaking images of AG Carinae, a luminous blue variable star surrounded by a glowing halo of gas and dust. The star is in a constant battle to maintain stability due to its massive form and super-hot temperatures.
A new hydrogel-based material has been developed that mimics the structure of a lobster's underbelly, exhibiting remarkable fatigue-resistance and stretch properties. The material's angled architecture is thought to hinder crack propagation, allowing it to withstand repeated stretches and strains without tearing.
New research from the Cornell Lab of Ornithology analyzes the impact of a bird eye disease on house finch populations, revealing an escalating arms race between the birds' immune systems and bacterial strains. The study suggests that imperfect immunity is driving this battle, with bacteria evolving to overcome strengthened finch defenses.
Researchers at the University of Cincinnati found that a protein in skeletal muscle fibers regulates the body's fight or flight response, enabling quick bursts of power. This discovery may lead to advancements in understanding and addressing skeletal muscular disorders.
Researchers at the University of Bonn describe a new octopus species, Emperor dumbo, using high-field MRI and micro-computed tomography. The study reveals special characteristics such as long suckers on each arm and a shorter web between arms than in other species.
Researchers at Osaka University and JOANNEUM RESEARCH developed ultrathin self-powered e-health patches that can monitor a user's pulse and blood pressure. The patches use embedded piezoelectric nanogenerators to harness biomechanical energy, enabling wireless health monitoring without the need for wires or batteries.
Researchers discovered that strawberry geranium (Saxifraga stolonifera) suppresses excessive immune response mediated by Toll-like receptor 2, reducing skin inflammation. This finding offers a potential alternative to conventional antibiotics and steroid-like compounds used to control dermatitis.
The study presents two new derivatives of pyrrole-fused azacoronene, one with alkyl groups and the other with concave π-planes, exhibiting distinct redox properties and π-electron functions. The curved structure leads to a strong interaction with spherical fullerene.
The NIH has established a new clinical research network called Childhood Asthma in Urban Settings (CAUSE) to study pediatric asthma in low-income urban settings. The network aims to develop tailored treatment and prevention approaches for children living in these communities.
Scientists at NUST MISIS created new magnesium alloys that can reduce the weight of heat-removing elements in electric vehicles and consumer electronics by one third. The alloys offer high thermal conductivity and low cost, making them suitable for modern gadgets.
Researchers at Stanford University developed an optical device that allows engineers to change the frequencies of individual photons in a stream of light. This enables the creation of compact and flexible neural networks for artificial intelligence, transforming fields such as digital communications, AI, and quantum computing.
Recent polls of people aged 14 to 24 reveal most young people are taking COVID-19 seriously and motivated by a desire to protect others. They prioritize following public health guidance when near close contacts or in 'pod' situations.
Researchers at Uppsala University have discovered that macrophages, a common immune cell, play a crucial role in re-establishing blood flow in damaged tissue. This finding could lead to the development of new treatments for cardiovascular diseases by increasing local concentrations of signal substances in damaged muscles.
Researchers discovered that organisms like plants, fungi, and corals use gene conversion to inherit less mutated oDNA, unlike humans and animals which rely on a bottleneck process. This finding could have implications for crop plants where gene conversion can cause sterility.
The Marsquake Service has detected over 500 marsquakes, with most being high-frequency events occurring at great distances. Low-frequency events are less common and appear to decay more quickly than expected.
A new study found that while COVID-19 mother-to-newborn transmission is rare, socially vulnerable mothers' worsening illness increases the risk of preterm birth and related health complications. Newborns tested positive at a rate five times higher than others
A study evaluates the impact of COVID-19 infection on cardiac corrected QT interval changes, finding alterations in both patients with and without the infection. The research suggests that early phase treatment for COVID-19 may lead to significant cardiac changes.
A study found that maternal SARS-CoV-2 infection is associated with poorer health outcomes in perinatally exposed newborns. The study examined test result positivity rates and health outcomes among mothers infected during pregnancy or childbirth.
A comprehensive study finds that many global groundwater wells are at risk of running dry due to declining water levels. The researchers analyzed construction records and monitoring well data from 40 countries, finding that 6-20% of wells may dry up if water levels continue to decline.
Scientists from US and Iran are collaborating on restoring Lake Urmia, which has lost 95% of its volume over two decades. The team's findings show that setting a target water level may not solve the lake's problems, highlighting the need for ecosystem-based restoration efforts.
A team of researchers at RIKEN CPR has demonstrated a successful cancer therapy using artificial metalloenzymes to deliver targeted drug therapies. In mouse tests, they found a 40% survival rate for mice treated with selective cell therapy and a higher survival rate over 77 days when targeting tumors that had already formed.
A study by University of Copenhagen researchers reveals how sugar molecules bind to cell receptors, activating the immune system in autoimmune diseases. The discovery also sheds light on the development of Alzheimer's disease, identifying a potential natural sugar that binds to the Siglec-3 receptor.
Researchers at the University of Basel have proposed a new scheme for measuring magnetic or electric fields using quantum steering, which enhances measurement precision. By analyzing entangled particle states, scientists can make more accurate predictions about possible measurement results.
A high school junior has built a low-cost seismometer device that detects earthquakes with accuracy and provides users with a few seconds of warning to take action. The device, costing less than $100 to make, has been successfully tested and detected several recent earthquakes in Southern California.
Researchers have identified the activation mechanism of SHP2, a key player in cancer development. The study reveals that flexible beta sheets, not previously thought to be crucial, open in the presence of a peptide, triggering SHP2 activation.
Research reveals that cell connections and surrounding tissue stiffness dictate cellular behavior, leading to cancer development. Cells can switch between contractile and extensile modes of motion, affecting their interactions and overall movement.
A new study identifies three molecules in the blood that can distinguish between heart attack and chest pain caused by other conditions. The researchers hope to develop a simple blood test for early diagnosis, which could help doctors quickly confirm or rule out a heart attack.
A new study highlights the importance of comprehensive NICU discharge planning in preparing parents to care for their medically needy infants at home. Families who were both satisfied and prepared had better outcomes than those who were not, with higher-risk groups benefiting from additional education and training.
Researchers realized efficient frequency conversion in microresonators via a degenerate sum-frequency process, achieving cross-band frequency conversion and amplification of converted signal. The study demonstrated precise tuning of the frequency window with a 42% efficiency and a 250GHz tuning bandwidth.
The study reveals two competing theories on lithium metal dendrite growth through ceramic electrolytes, proposing a new mechanism for solid-state battery failure. The researchers used X-ray computed tomography and spatially mapped X-ray diffraction to visualize and characterize crack growth and dendrite propagation.
A joint research study by SFU and the Pacific Water Research Centre highlights the need for certified, nature-based solutions to protect salmon habitats in the Lower Mainland. Adopting urban development policies and certifications can advance progressive land and water management.
A new heterogeneous coupling catalyst for OCM has been developed, achieving a C2 yield of 10.9% at low temperatures. The catalyst's surface coupling mechanism controls the formation of C2 species, increasing selectivity and yield.
Researchers developed a test using artificial intelligence to measure proteins in advanced bowel cancer patients, predicting treatment benefits. The technique could help doctors and patients decide on the best treatment options, targeting those with higher protein levels.
Researchers at Massachusetts General Hospital develop a new radiation technique that carefully targets tumors while sparing surrounding tissues, reducing inflammation and preserving swallowing function. The study shows promising results in patients with localized lung cancer, with none developing severe esophagitis despite high-dose ra...
Researchers developed an ankle exoskeleton that significantly increased self-selected walking speed in young adults, with a 42% average increase. The device has potential for improving daily life and may also reduce pain caused by weight on joints or improve balance in older adults.
Scientists have discovered fossils of three new species of giant cloud rats in Philippine caves, dating back tens of thousands of years. The rodents filled an ecological role similar to that of squirrels in the US and were resilient for at least 60,000 years, but two of the species disappeared around 2,000 years ago.
The UVA Center for Engineering in Medicine has developed a robust process to help researchers win funding from institutions like the National Institutes of Health. The center's first seed grant cohorts have achieved astonishing results, including $12 million in follow-on funding with just a $2 million initial investment.
Researchers adapted an algorithm to identify similarities in escort ads, highlighting common parts and indicating potential human trafficking activity. The InfoShield algorithm outperformed other algorithms at identifying trafficking ads with 85% precision, flagging them without false positives.
A minimally invasive retinal reattachment procedure using pneumatic retinopexy leads to better long-term integrity of photoreceptors compared to more invasive procedures. This technique achieves superior visual outcomes by allowing the retina to reattach naturally and minimize damage to critical cells.
A study from Rockefeller University suggests that breakthrough COVID cases may be driven by rapid evolution of the virus. Ongoing testing of immunized individuals is crucial to mitigate future outbreaks.
Scientists have discovered a potential new therapy target for canine cancer, specifically oral malignant melanoma in dogs. The treatment targets the PD-L1 molecule, which has shown promise in human cancer treatments, and significantly increased survival time for dogs with pulmonary metastatic OMM.
A Rutgers University study found that states with stricter firearms laws reported lower suicide and homicide rates. The study analyzed data from 1991 to 2017 and found a significant correlation between the total number of firearm laws in a state and its corresponding suicide and homicide rates.
A new study by Florida Atlantic University's Harbor Branch Oceanographic Institute reveals that a common antibiotic, amoxicillin, is effective in treating stony coral tissue loss disease. The study showed a 95% success rate in healing individual lesions, but did not prevent the development of new lesions over time.
Researchers analyzed California wildfire data from 2000-2019, finding the annual burn season has lengthened and the yearly peak shifted from August to July, fueled by climate change and human-caused ignitions. Small fires account for most incidents, but large fires have deadly consequences.
The University of Minnesota will host a new Organ and Tissue Preservation Center, focusing on technologies to rapidly rewarm cryopreserved organs. This center is part of the Biostasis Research Institute's 'Apollo Program' to develop new preservation methods for human organs.
New research reveals that using both e-cigarettes and tobacco cigarettes increases the risk of developing respiratory symptoms like cough and wheeze. Dual users had a 1.9-times higher odds of developing respiratory symptoms compared to exclusive e-cigarette or tobacco smoker users.
Researchers discovered that distinct Notch family members are modified differently by phosphorylation, leading to opposite effects on transcriptional activity and oncogenic behavior. The study suggests that targeting PIM or Notch proteins may provide new treatment options for hormone-dependent breast cancer with poor prognosis.
A new analysis suggests China needs to reduce carbon emissions by over 90% and energy consumption by almost 40% to achieve the 1.5°C target, with industry being the main emission contributor. The study also highlights the need for more research on economic consequences of working towards this goal.
Researchers at Karolinska Institutet have developed a new astrocyte-specific PET tracer, BU99008, which detects reactive astrogliosis in the brain. This finding could improve early diagnosis of Alzheimer's disease, with potential implications for other disorders related to astroglial dysfunction.
A team from Regenstrief Institute created an emergency EMR for Indianapolis first responders in just one week using OpenMRS, a global open-source electronic medical record system. The system allowed for quick registration of patients, collection of basic clinical information, and transmission to the Indiana health information exchange.