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Finding the source of chemical reactions

Scientists at Argonne National Laboratory have experimentally detected the transition state in chemical reactions, a hidden aspect that controls product formation. This breakthrough could improve industrial processes and lead to the synthesis of new life-saving drugs.

SourceDOE/Argonne National Laboratory·JournalProceedings of the National Academy of Sciences·DateFeb 3, 2020

The coldest reaction

Researchers at Harvard University have achieved the coldest chemical reaction in history, slowing down molecules to capture the critical act of bond formation. By utilizing ultracold temperatures, they observed the intermediate stage of the reaction for microseconds, enabling direct measurement and validation of theories.

SourceHarvard University·JournalScience·DateNov 28, 2019

Strained, symmetric, and new

Tetravinylallene, a highly unsaturated molecule with two adjacent double bonds, has been synthesized for the first time, offering a new approach to constructing complex molecular frameworks. Its symmetry enables chemists to perform multiple reactions in one step, making it a potent tool for synthesizing natural products and drugs.

SourceWiley·JournalAngewandte Chemie International Edition·DateSep 30, 2019

Building on UD, Nobel legacy

Researchers have discovered a new reaction that enables the production of indoline scaffolds, which are crucial for developing new medicines. By using nitrogen as a catalyst, the reaction can create complex assemblies more easily and efficiently.

SourceUniversity of Delaware·JournalAngewandte Chemie·DateSep 23, 2019

Blink and you'll miss it

Scientists have successfully observed and controlled fast-paced chemical reactions using light, which could lead to new optical nanotechnology. The method uses ultrafast techniques to visualize the reaction, offering insights into molecular interactions and potential applications in materials design.

SourceUniversity of Tokyo·JournalNature Communications·DateSep 13, 2019

Chemistry in motion

For the first time, researchers have visualized chemical processes in unprecedented detail using molecular electron microscopy. This breakthrough allows for the observation of discrete stages in chemical reactions, which could aid in the development of methods to synthesize chemicals with greater control and precision.

SourceUniversity of Tokyo·JournalNature Communications·DateAug 23, 2019

Pairing prediction and production in AI-informed robotic flow synthesis

Researchers present an integrated strategy for computer-augmented chemical synthesis, successfully yielding 15 different medicinally related small molecules. Their AI-informed, robotically controlled platform has the potential to greatly improve the synthesis of complex molecules, reducing manual labor and increasing scalability.

Researchers build artificial cells that sense and respond to their environment

Artificial cells have been created by Imperial College London scientists that can sense changes in their surroundings and respond with drug molecules or harm removal. This breakthrough uses a simpler approach to mimic complex biological responses, making it easier to engineer artificial cells for various biotechnological applications.

SourceImperial College London·JournalProceedings of the National Academy of Sciences·DateJul 29, 2019

Atomically precise models improve understanding of fuel cells

Researchers at Kyushu University developed computer simulations using realistic atomic-scale models to understand reaction pathways in solid-oxide fuel cells. The study found that reactions are more likely to occur in layers with smaller pore sizes, but also identified a new degradation pathway that could impact performance.

SourceKyushu University·JournalCommunications Chemistry·DateJul 19, 2019

Controlling instabilities gives closer look at chemistry from hypersonic vehicles

A team of researchers used a reduced order model to analyze data from high-fidelity simulations, gaining new knowledge about chemical reactions in hypersonic flows. The study looked at three types of gas compositions and found that vibrations temperatures could be predicted, as well as the formation of nitric oxide in small amounts.

Odd reaction creates a stir in the lab

Researchers at Rice University discovered that PTFE stir bars react with chemicals in an unexpected way, affecting the modification of nanotubes. This discovery highlights the importance of choosing inert materials in laboratory settings.

SourceRice University·JournalACS Omega·DateMar 29, 2019

Converting biomass by applying mechanical force

Researchers at the University of Münster have identified a new reaction mechanism for converting biomass into fuels and chemicals using mechanical force. The mechano-catalytic reaction reduces energy requirements and eliminates unnecessary steps, leading to a more efficient and environmentally friendly process.

SourceUniversity of Münster·JournalAngewandte Chemie International Edition·DateMar 14, 2019

Medieval inks for heritage conservation

The Meridies Medieval History research group at the University of Cordoba collaborated with chemists to replicate five medieval inks. The team analyzed handwritten recipes, translated texts, and analyzed chemical reactions to recreate the exact same inks used six centuries ago.

SourceUniversity of Córdoba·JournalHeritage Science·DateFeb 5, 2019