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Mixing things up: optimizing fluid mixing with machine learning

A team of Japanese researchers used reinforcement learning to study fluid mixing during laminar flow, achieving exponentially fast mixing without prior knowledge. The method also enabled effective transfer learning, reducing training time for new mixing problems, and has potential applications across various industries.

SourceTokyo University of Science·JournalScientific Reports·TypeComputational simulation/modeling·DateAug 29, 2022

Simulations provide map to treasure trove of fluorinated compounds

Researchers at Hokkaido University used computer simulations to discover a reaction that selectively adds two fluorine atoms to a difficult-to-access position on an N-heterocycle. The successful synthesis of 48 new compounds with unique alpha position fluorine substitutions has significant potential for novel drug development.

SourceHokkaido University·JournalNature Synthesis·TypeComputational simulation/modeling·DateAug 8, 2022

Water can’t touch this sanded, powdered surface

Rice University researchers create a technique to make surfaces superhydrophobic by combining sanding with powder materials, resulting in water-repelling properties. The treatment also exhibits excellent anti-icing properties, slowing down freezing and reducing ice adhesion strength.

SourceRice University·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateAug 4, 2022

New magnesium superionic conductor towards lithium-free solid-state batteries

Researchers from Tokyo University of Science create a metal–organic framework-based magnesium ion conductor showing superionic conductivity at room temperature, overcoming the limitations of magnesium ion-based energy devices. The novel Mg2+ electrolyte exhibits a high conductivity of 10−3 S cm−1, making it suitable for battery applica...

SourceTokyo University of Science·JournalJournal of the American Chemical Society·TypeExperimental study·DateAug 4, 2022

A light twist

A researcher at the University of Tsukuba has developed a method for producing electrically conductive polymers with helical configurations, which can convert linearly polarized light into circular polarization. This approach may lead to cheaper and more energy-efficient electronic displays.

SourceUniversity of Tsukuba·JournalMolecular Crystals and Liquid Crystals·DateJun 16, 2022

New material paves the way for remote-controlled medication and electronic pills

Researchers at Chalmers University of Technology have invented a material that uses electrical signals to separate biomolecules, paving the way for efficient production of biomedicines. The material's ability to function in biological fluids with buffering capacity enables remote-controlled drug release and reduces energy consumption.

SourceChalmers University of Technology·JournalAngewandte Chemie·TypeExperimental study·DateJun 15, 2022

Chemists design chemical probe for detecting minute temperature shifts in the body

Researchers at Colorado State University have developed a cobalt-based molecule that can detect extremely subtle temperature shifts inside the body, opening up new possibilities for medical imaging and therapy. The noninvasive probe uses radiofrequency waves to read out temperature signals from the body.

SourceColorado State University·JournalJournal of the American Chemical Society·TypeExperimental study·DateJun 6, 2022

Researchers bridge the gap between disciplines to better understand chemical reactions

Researchers at Simon Fraser University have discovered a deep connection between two previously distinct fields of physics, stochastic thermodynamics and transition-path theory, allowing for a framework to quantify reaction information. This framework enables researchers to separate signal from noise in massive datasets, facilitating b...

SourceSimon Fraser University·JournalPhysical Review Letters·DateMay 2, 2022

Hitting rewind to predict multi-step chemical reactions

A new method predicts the starting materials and reaction paths of multi-step chemical reactions using only information about the target product molecule. The algorithm reduces the number of paths to explore, mitigating the combinatorial explosion that occurs in single-step reactions.

SourceHokkaido University·JournalJACS Au·TypeComputational simulation/modeling·DateApr 25, 2022

Glowing spider fossils prompt breakthrough study of how they were preserved at Aix-en-Provence

Researchers at the University of Kansas discovered that microalgae-produced diatoms played a crucial role in preserving ancient spider fossils at Aix-en-Provence. The unique chemical process, similar to industrial vulcanization, stabilized carbon-based exoskeletons and promoted sulfurization, resulting in exceptional fossil preservation.

SourceUniversity of Kansas·JournalCommunications Earth & Environment·DateApr 21, 2022

Hope for inflammatory bowel disease with novel “green” synthesis of drug candidate

Researchers at Okayama University have developed a novel 'green' synthesis technique for the production of NEt-3IB, a promising small-molecule oral drug candidate for inflammatory bowel disease (IBD). The new method produces large quantities of NEt-3IB with high purity and a total yield of over 30%, using only recoverable organic solve...

SourceOkayama University·JournalChemical and Pharmaceutical Bulletin·TypeCommentary/editorial·DateMar 11, 2022

Novel enzyme catalyzing the formation of glycosidic bonds in complex sugar moieties characterized

Researchers have identified a novel enzyme that catalyzes the formation of glycosidic bonds in complex sugar moieties. The discovery provides fresh insights into carbohydrate metabolism and offers a breakthrough for the synthesis of sugar chains, which play key roles in various biological processes.

SourceTokyo University of Science·JournalJournal of Biological Chemistry·TypeExperimental study·DateMar 7, 2022

Molecule snapshot by explosion

Researchers at the European XFEL facility have taken pictures of gas-phase iodopyridine molecules at atomic resolution using ultra-bright X-ray pulses. The images were reconstructed from the fragments caused by a Coulomb explosion, providing unprecedented clarity for this method and molecule size.

SourceGoethe University Frankfurt·JournalNature Physics·TypeExperimental study·DateFeb 21, 2022

New technology fused with photosynthetic life offers path to green energy

Researchers at Arizona State University have developed a hybrid device that combines living organisms with bio batteries to produce stored energy under light conditions. The technology, known as microbial electro photosynthesis, has the potential to power a wide range of products, including transportation fuels and cosmetics.

SourceArizona State University·JournalJournal of the American Chemical Society·TypeExperimental study·DateFeb 20, 2022

Researchers train neural network to recognize chemical formulas from research papers

A team of researchers from Skoltech and universities developed a neural network-based solution for automated recognition of chemical formulas on research paper scans. The algorithm combines molecules, functional groups, fonts, styles, and printing defects to mimic existing molecular template depiction styles.

New study suggests an alternative technique for determining the true activity of catalysts

Researchers from Waseda University have developed an alternative technique, sampled current voltammetry (SCV), to accurately determine the activity of electrocatalysts used in water-splitting reactions. The study shows that SCV can provide reliable measurements of electrocatalytic performance at constant steady-state applied voltages.

SourceWaseda University·JournalJournal of The Electrochemical Society·TypeExperimental study·DateJan 31, 2022

Review highlights potential of structural proteomics for treating neurodegenerative diseases

A recent review highlights the potential of structural proteomics in understanding pathological processes and predicting drug candidates for neurodegenerative diseases. The field combines protein chemistry and mass spectrometry to determine protein structure and interactions, which can lead to breakthroughs in treating serious health c...

Suiting up with Al-Mg-Si: New protective coating for steel to resist corrosion in ships and marine and coastal facilities and structures

Scientists have created a new protective coating using Al-Mg-Si alloy to resist corrosion in ships and marine facilities. The coating demonstrates improved corrosion resistance through a 'shielding effect', increasing the economic life of steel machinery.

SourceNational Korea Maritime and Ocean University·JournalCorrosion Science·TypeExperimental study·DateJan 5, 2022

The link between electrical voltage and brain flexibility a new study by Tel Aviv university found, for the first time; a direct and significant link between changes in G-protein-coupled receptors and the brain’s ability to adapt to external changes

A Tel Aviv University study found a significant link between changes in G-protein-coupled receptors and brain adaptability. Disabling the voltage sensor of these proteins caused uncontrolled brain flexibility, leading to excessive habituation to odors.

SourceTel-Aviv University·JournalNature Communications·DateJan 4, 2022

Iodine in desert dust destroys ozone

A new CU Boulder study reveals that iodine from desert dust can decrease ozone air pollution but prolong greenhouse gas lifetimes. The finding has significant implications for air quality and climate, forcing researchers to re-evaluate how particles from land impact the atmosphere's chemistry.

SourceUniversity of Colorado at Boulder·JournalScience Advances·TypeData/statistical analysis·DateDec 22, 2021

These tiny liquid robots never run out of juice as long as they have food

Researchers at Lawrence Berkeley National Laboratory have developed water-walking liquid robots that can retrieve and deliver precious chemicals autonomously. The robots use chemistry to control buoyancy and do not require electrical energy, making them ideal for applications such as chemical synthesis and drug delivery.

SourceDOE/Lawrence Berkeley National Laboratory·JournalNature Chemistry·TypeExperimental study·DateDec 8, 2021

Before geoengineering, some fundamental chemistry

A new study suggests that atmospheric conditions in the stratosphere pose a challenge to generating sulfuric acid, a crucial component of a proposed geoengineering strategy to mitigate climate change. Researchers found that solar radiation causes HOSO2 to quickly photolyse, breaking it down into harmful sulfur dioxide, which may reduce...

SourceUniversity of Pennsylvania·JournalJournal of the American Chemical Society·TypeComputational simulation/modeling·DateNov 22, 2021

Czech scientists become first to observe an inhomogeneous electron charge distribution on an atom

Scientists confirm existence of sigma-hole, a phenomenon previously predicted but never directly observed. This breakthrough enables understanding of interactions between individual atoms or molecules, facilitating refinement of material and structural properties.

Tiny droplets offer glimpse of real life inside a living cell

Researchers at Okinawa Institute of Science and Technology (OIST) have developed a system to study cellular reactions in a way that more closely reflects how molecules behave in a living cell. By mixing a polymer with protein, they created membraneless droplets that can mimic the molecular properties of how molecules move in the cell.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeExperimental study·DateNov 10, 2021

Sperm switch swimming patterns to locate egg

A new study reveals how sperm change their swimming patterns to navigate to the egg, shifting from symmetrical to asymmetrical motion. This change in behavior, called hyperactivation, enables the sperm to sweep the area once in the egg's proximity.

SourceCornell University·JournalProceedings of the National Academy of Sciences·DateNov 1, 2021