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Latest in body art? ‘Tattoos’ for individual cells

Researchers at Johns Hopkins University have developed nanoscale tattoos that can stick to live cells, allowing for the first time to monitor and control individual cell health in real-time. This technology bridges the gap between living cells and conventional sensors, enabling early disease diagnosis and treatment.

SourceJohns Hopkins University·JournalNano Letters·TypeExperimental study·DateAug 7, 2023

Fiber-infused ink enables 3D-printed heart muscle to beat

Researchers at Harvard developed a fiber-infused ink that allows 3D-printed heart muscle cells to align and contract like human heart cells, enabling the creation of functional heart ventricles. The innovation can be used to build life-like heart tissues with thicker muscle walls, paving the way for regenerative therapeutics.

Healing power of light: University of Ottawa team advances clear vision for eye repair

The study, published in Advanced Functional Materials, reveals a novel light-activated material that can be used to effectively reshape and thicken damaged corneal tissue, promoting healing and recovery for patients with keratoconus. The technology has tremendous potential to impact millions of people suffering from corneal diseases.

SourceUniversity of Ottawa·JournalAdvanced Functional Materials·TypeRandomized controlled/clinical trial·DateJul 25, 2023

A novel hydrogel may be a beacon of hope for infertility and fertility challenges

A novel hydrogel has been developed to induce endometrial regeneration and elucidate its mechanism, offering new hope for patients struggling with infertility. The gel, made from uterus-derived decellularized extracellular matrix, successfully regenerated the endometrium in mice, creating a favorable environment for embryo implantation.

SourcePohang University of Science & Technology (POSTECH)·JournalAdvanced Functional Materials·DateJul 3, 2023

Tuning T cell traits and functions with biomechanical materials

A research team at the Wyss Institute engineered a 3D model of extracellular matrix to study the impact of tissue mechanics on T cells. They found that viscoelasticity played a crucial role in shaping T cell traits and functions, enabling the creation of functionally distinct T cell populations for adoptive therapies.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalNature Biomedical Engineering·TypeExperimental study·DateJun 26, 2023

3D 'bio-printing' inside hydrogels

Researchers achieve 3D printing within mini-organs growing in hydrogels, allowing for precise control over shape, activity, and tissue growth. This breakthrough enables the creation of realistic models of organs and disease, with potential applications in cancer research and treatment.

SourceUniversity College London·JournalNature Communications·DateJun 9, 2023

Gwangju Institute of Science and Technology researchers develop injectable bioelectrodes with tunable lifetimes

Researchers from GIST have developed graphene-based conductive hydrogels that are injectable, degradable, and highly compatible with biological systems. The novel electrodes outperform traditional metal electrodes in signal transmission and stability, offering promising solutions for long-term medical monitoring and treatment.

SourceGIST (Gwangju Institute of Science and Technology)·JournalSmall·TypeExperimental study·DateMay 10, 2023

Researchers develop flexible sweat sensor based on photonic cellulose nanocrystal

A sustainable, insoluble, and chiral photonic cellulose nanocrystal patch enables calcium ion (Ca2+) sensing in sweat. The researchers developed a simple method to fabricate CNC-based hydrogels, which exhibit freeze resistance, strong adhesion, good biocompatibility, and high sensitivity to Ca2+.

SourceDalian Institute of Chemical Physics, Chinese Academy Sciences·JournalSmall·TypeCommentary/editorial·DateMay 8, 2023

The Texas Heart Institute and The University of Texas at Austin awarded a National Institutes of Health grant to develop injectable hydrogel electrodes to prevent ventricular arrhythmias

The Texas Heart Institute and The University of Texas at Austin receive a four-year, $2.37 million NIH grant to develop injectable hydrogel electrodes for preventing and managing ventricular arrhythmias. Researchers have already demonstrated the feasibility of pacing the heart using the hydrogel in a porcine model.

HKU Mechanical Engineering team develops electroconductive hydrogel for biomedical applications

A research team from HKU has developed a new type of electroconductive hydrogels with outstanding mechanical strength and manufacturability, enabling various bioelectronic devices. The material shows high electrical conductivity and mechanical strength, making it suitable for applications such as neural prosthetics and cardiac patches.

SourceThe University of Hong Kong·JournalNature Communications·TypeExperimental study·DateMay 3, 2023

How spheres become worms

Scientists have identified a novel mechanism of gel formation in synthetic polymers, which leads to the creation of worm-like structures. This breakthrough has significant implications for biofabrication and could lead to the development of new medical implants, contact lenses, and other applications.

SourceUniversity of Würzburg·JournalACS Nano·TypeExperimental study·DateApr 27, 2023

Highly sensitive and self-healing conductive hydrogels fabricated from cationic cellulose nanofiber-dispersed liquid metal for strain sensors

The study developed conductive hydrogels with high sensing performance, excellent stretchability, and tensile strength, thanks to the use of cationic cellulose nanofiber-dispersed liquid metal. The hydrogels demonstrated a very high sensing sensitivity and good repeatability and durability.

SourceScience China Press·JournalScience China Materials·DateApr 20, 2023

Channeling mechanical energy in a preferred direction

Researchers at RIKEN have created a composite material that can channel mechanical energy in one direction but not the other, allowing for efficient use of random vibrations. This property is essential for various biological functions and has potential applications in electronics, photonics, magnetism, and sound.

SourceRIKEN·JournalScience·TypeExperimental study·DateApr 13, 2023

Simple but revolutionary modular organoids

Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...

SourceRIKEN·JournalCommunications Biology·TypeExperimental study·DateApr 6, 2023

Pusan National University researchers develop portable color-changing food spoilage sensor

Researchers at Pusan National University have created a portable molecular sensor that detects biogenic amines released from spoiled food using polydiacetylene-based beads. The sensor, which changes color to red upon binding with BAs, can be used for rapid visual detection of spoiled food during storage and distribution.

SourcePusan National University·JournalFood Chemistry·TypeExperimental study·DateMar 21, 2023

Ultra-soft and highly stretchable hydrogel-based sensor for monitoring overactive bladder

Researchers developed a hydrogel-based sensor to monitor overactive bladder activity in real-time. The sensor measures both mechanical and bioelectrical activities, allowing for simultaneous monitoring and neural stimulation. This breakthrough has the potential to improve treatment outcomes and minimize side effects.

SourcePohang University of Science & Technology (POSTECH)·JournalBiosensors and Bioelectronics·DateMar 8, 2023

Healing the brain: Hydrogels enable neuronal tissue growth

Researchers at Hokkaido University used hydrogel materials in combination with neural stem cells to grow new brain tissue in areas of brain damage. The study showed that immune cells and blood vessels grew within the hydrogels, leading to some degree of integration between the hydrogel and host brain tissue.

SourceHokkaido University·JournalScientific Reports·TypeExperimental study·DateFeb 23, 2023

Bite this! Mosquito feeding chamber uses fake skin, real blood

Rice University researchers have developed an innovative system to study mosquito feeding behavior using fake skin made with a 3D printer, eliminating the need for live volunteers. The system was tested on various mosquito repellents and showed promising results, suggesting it could be scaled up for future studies.

SourceRice University·JournalFrontiers in Bioengineering and Biotechnology·TypeExperimental study·DateFeb 9, 2023

New synthetic skin may unlock blood-sucking secrets of mosquitoes

Researchers have developed a new synthetic skin, made of hydrogels, to study how mosquitoes transmit deadly diseases. The hydrogel system can mimic different blood vessel patterns, allowing for more consistent testing and analysis. This breakthrough may help identify ways to prevent the spread of disease.

SourceTulane University·JournalFrontiers in Bioengineering and Biotechnology·TypeExperimental study·DateFeb 9, 2023

A soft, stimulating scaffold supports brain cell development ex vivo

A new type of electrically conductive hydrogel scaffold has been developed to support brain cell growth and differentiation. The scaffold mimics the soft conditions of brain tissue and enables the creation of implantable biohybrid BCIs that integrate with a patient's brain tissue.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalAdvanced Healthcare Materials·TypeExperimental study·DateJan 5, 2023

Better transplants for better joints: A closer look at micromechanical mismatch influences in cartilage regeneration

A team of scientists from TIBI, UIC, and POSTECH has elucidated key points on how cartilage generation is facilitated and alternative bone formation can be avoided. They found optimal conditions for better cartilage regeneration while reducing excessive cartilage formation using human mesenchymal stem cells.

SourceTerasaki Institute for Biomedical Innovation·JournalMatter·TypeExperimental study·DateDec 21, 2022

Scientists' use of hydrogel materials leads to stem cells developing like human embryos

Researchers at UNSW Sydney have successfully induced a gastrulation-like event in human pluripotent stem cells, mimicking the early stages of embryonic development. This breakthrough could lead to new approaches for studying human development and creating personalized body tissue or organs using hydrogel materials.

SourceUniversity of New South Wales·JournalAdvanced Science·TypeExperimental study·DateDec 15, 2022

SLAS Technology's December issue looks at a 3D printed model for improving vasodilation research

A new method for creating freestanding hydrogel lumens that can accurately replicate blood vessels and facilitate vasodilation research. This approach allows researchers to study vasodilation in a more efficient and effective manner, overcoming limitations of existing methods.

SourceSLAS (Society for Laboratory Automation and Screening)·JournalSLAS TECHNOLOGY·TypeExperimental study·DateDec 14, 2022

CityU develops two novel hydrogen production catalysts based on mineral gel and "crystalline-amorphous" dual-phase nano-aluminium alloy

Researchers from City University of Hong Kong developed a new ultra-stable hydrogen evolution reaction electrocatalyst based on two-dimensional mineral gel nanosheets. The catalyst exhibits excellent electrocatalytic activity and long-term durability, with an overpotential of only 38.5 mV at 10 mA cm−2.

SourceCity University of Hong Kong·JournalNature Communications·TypeExperimental study·DateDec 1, 2022

Non-hormonal gel proves effective at helping mucus block sperm, with low risk of side effects

A new non-hormonal gel blocks sperm by reinforcing cervical mucus barrier, demonstrating high effectiveness in reducing uterine sperm numbers. The gel has shown a 98% average decrease in sperm numbers compared to untreated control animals, making it a promising alternative to existing contraceptives.

SourceKTH, Royal Institute of Technology·JournalScience Translational Medicine·TypeObservational study·DateNov 30, 2022