Researchers at UNIST developed a microfluidic system to process blood into artificial tissue scaffolds for vascular regeneration. Autologous blood-based implants demonstrated superior wound closure rates, increased epidermis thickness, and enhanced collagen deposition in rodent skin wounds.
Researchers developed a novel approach called 'countercation engineering' to impart thermoresponsiveness to graphene-oxide nanosheets. The method involves synthesizing GO nanosheets with specific countercations, resulting in inherent thermoresponsive behavior without the need for thermoresponsive polymers.
Researchers at Johns Hopkins University have developed nanoscale tattoos that can stick to live cells, allowing for the first time to monitor and control individual cell health in real-time. This technology bridges the gap between living cells and conventional sensors, enabling early disease diagnosis and treatment.
Researchers explore techniques to enhance mechanical and electrical performance of hydrogel sensors, enabling harsh environment resistance, human skin compatibility, and intelligent data processing. Hydrogels' toughness and conductive capabilities make them suitable for wearable electronics applications.
Researchers at Harvard developed a fiber-infused ink that allows 3D-printed heart muscle cells to align and contract like human heart cells, enabling the creation of functional heart ventricles. The innovation can be used to build life-like heart tissues with thicker muscle walls, paving the way for regenerative therapeutics.
The Bioaction project leverages bacteria as allies in promoting tissue regeneration, offering a paradigm shift in addressing infections. By developing functional bio-hydrogels, the project aims to accelerate healing and stimulate bone growth, reducing reliance on extended antibiotic therapies.
The study, published in Advanced Functional Materials, reveals a novel light-activated material that can be used to effectively reshape and thicken damaged corneal tissue, promoting healing and recovery for patients with keratoconus. The technology has tremendous potential to impact millions of people suffering from corneal diseases.
A novel hydrogel has been developed to induce endometrial regeneration and elucidate its mechanism, offering new hope for patients struggling with infertility. The gel, made from uterus-derived decellularized extracellular matrix, successfully regenerated the endometrium in mice, creating a favorable environment for embryo implantation.
A research team at the Wyss Institute engineered a 3D model of extracellular matrix to study the impact of tissue mechanics on T cells. They found that viscoelasticity played a crucial role in shaping T cell traits and functions, enabling the creation of functionally distinct T cell populations for adoptive therapies.
Researchers at UBC develop biodegradable gel that mimics articular cartilage properties, allowing for faster and more efficient cartilage regeneration. The gel's ability to resist compression and recover its shape after compression makes it a promising material for joint injury repair.
Researchers at MIT have created a metal-free, Jell-O-like material that can conduct electricity similarly to conventional metals. The material is made into a printable ink, which the researchers patterned into flexible, rubbery electrodes.
Researchers at MIT have developed a superabsorbent material that can soak up record amounts of moisture from the air, even in dry conditions. The material is made by infusing hydrogel with lithium chloride and has shown to absorb and retain unprecedented amounts of water vapor.
Researchers achieve 3D printing within mini-organs growing in hydrogels, allowing for precise control over shape, activity, and tissue growth. This breakthrough enables the creation of realistic models of organs and disease, with potential applications in cancer research and treatment.
Researchers created a new type of wound dressing material using advanced polymers, enabling customized dressings with fine-tuned surface adhesion. The material has potential applications in burn treatment and drug delivery for cancer patients, providing constant medication release outside the clinic setting.
Researchers at NC State University have developed a novel method for creating CO2 capture filters using 3D printing. The filters, made from a hydrogel material infused with the enzyme carbonic anhydrase, captured 24% of CO2 in a gas mixture and retained 52% of its performance after over 1,000 hours. This technology has potential applic...
McGill researchers are developing a new technique using 3D printing and hydrogels to create biomedical devices that conform to the human body. This emerging technology, called soft ionotronics, has the potential to improve wearable and implantable devices, such as strain sensors for neuromuscular rehabilitation.
Researchers from GIST have developed graphene-based conductive hydrogels that are injectable, degradable, and highly compatible with biological systems. The novel electrodes outperform traditional metal electrodes in signal transmission and stability, offering promising solutions for long-term medical monitoring and treatment.
A team of researchers from the University of Oklahoma and Yale University has developed a super-resolution imaging platform technology to visualize nanoparticles within cells. The technique, called expansion microscopy, enables 3-D imaging with resolutions as low as 10 nanometers, allowing for safer and more efficient nanomedicines.
A sustainable, insoluble, and chiral photonic cellulose nanocrystal patch enables calcium ion (Ca2+) sensing in sweat. The researchers developed a simple method to fabricate CNC-based hydrogels, which exhibit freeze resistance, strong adhesion, good biocompatibility, and high sensitivity to Ca2+.
The Texas Heart Institute and The University of Texas at Austin receive a four-year, $2.37 million NIH grant to develop injectable hydrogel electrodes for preventing and managing ventricular arrhythmias. Researchers have already demonstrated the feasibility of pacing the heart using the hydrogel in a porcine model.
A research team from HKU has developed a new type of electroconductive hydrogels with outstanding mechanical strength and manufacturability, enabling various bioelectronic devices. The material shows high electrical conductivity and mechanical strength, making it suitable for applications such as neural prosthetics and cardiac patches.
A team of researchers has created a touch-responsive fabric armband that can be used as a keyboard or sketchpad. The device uses a pressure-sensitive hydrogel sandwiched between layers of knit silk to interpret user input, allowing for real-time writing and gaming on computers.
Scientists have identified a novel mechanism of gel formation in synthetic polymers, which leads to the creation of worm-like structures. This breakthrough has significant implications for biofabrication and could lead to the development of new medical implants, contact lenses, and other applications.
A new type of floatable photocatalytic platform composed of hydrogel nanocomposites efficiently proceeds hydrogen evolution reaction. The platform exhibits clear advantages over conventional systems, including efficient solar energy conversion and easy gas diffusion.
The study developed conductive hydrogels with high sensing performance, excellent stretchability, and tensile strength, thanks to the use of cationic cellulose nanofiber-dispersed liquid metal. The hydrogels demonstrated a very high sensing sensitivity and good repeatability and durability.
Researchers developed tendon-mimetic hydrogels with outstanding mechanical properties, including excellent Young's modulus and strength, by mixing aramid nanofibers with polyvinyl alcohol. These hydrogels show promising capabilities for tissue repair and implantable medical devices.
Researchers discovered a hydrogel material that maintains its ability to absorb moisture despite rising temperatures, contradicting intuition. The material, polyethylene glycol (PEG), doubles its water absorption between 25-50 degrees Celsius, making it suitable for passive cooling and water harvesting applications.
Scientists discovered a way to regulate the mechanical strength and recoverability of peptide hydrogels by manipulating incubation temperature and time. By controlling droplet formation, they created fibril networks with optimal properties for various applications.
Researchers at RIKEN have created a composite material that can channel mechanical energy in one direction but not the other, allowing for efficient use of random vibrations. This property is essential for various biological functions and has potential applications in electronics, photonics, magnetism, and sound.
Scientists discover carbonated water's impact on low-methoxy pectin hydrogel formation and properties. The study shows that CO2 from carbonated water increases mechanical strength and gelation rate of hydrogels.
Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...
SourceRIKEN·JournalCommunications Biology·TypeExperimental study·DateApr 6, 2023
Scientists developed an injectable biomaterial with improved adhesion, stretchability, and toughness, making it ideal for surgical wound sealing. The material showed superior adhesive strength, stability, and biocompatibility in physiological conditions.
Researchers at Pusan National University have created a portable molecular sensor that detects biogenic amines released from spoiled food using polydiacetylene-based beads. The sensor, which changes color to red upon binding with BAs, can be used for rapid visual detection of spoiled food during storage and distribution.
Researchers used a biomimetic model to study wound healing in burn and laceration wounds. Fibroblasts were found to clear away damaged tissue before depositing new material, but this process was slower in burn wounds due to more tissue damage. Therapies that promote wound clearance could accelerate healing.
Researchers developed a hydrogel-based sensor to monitor overactive bladder activity in real-time. The sensor measures both mechanical and bioelectrical activities, allowing for simultaneous monitoring and neural stimulation. This breakthrough has the potential to improve treatment outcomes and minimize side effects.
Researchers have developed a new 'hybrid' hydrogel that safely delivers stem cells to damaged brain tissue, repairing injuries in mice. The breakthrough solves a long-standing challenge and paves the way for potential treatments beyond the brain.
Researchers at Hokkaido University used hydrogel materials in combination with neural stem cells to grow new brain tissue in areas of brain damage. The study showed that immune cells and blood vessels grew within the hydrogels, leading to some degree of integration between the hydrogel and host brain tissue.
A new biomaterial platform mimics human skin to analyze mosquito feeding behavior, using machine learning models and video monitoring. The results show an average precision of 92.5%, with potential applications for developing more effective repellents to combat diseases.
SourceFrontiers·JournalFrontiers in Bioengineering and Biotechnology·TypeExperimental study·DateFeb 9, 2023
Rice University researchers have developed an innovative system to study mosquito feeding behavior using fake skin made with a 3D printer, eliminating the need for live volunteers. The system was tested on various mosquito repellents and showed promising results, suggesting it could be scaled up for future studies.
Researchers have developed an inhalable powder called SHIELD that reduces infection in mouse and non-human primate models by reinforcing the body's mucosal layer. The powder is composed of food-grade materials and biodegrades over a 48-hour period, providing protection for up to 8 hours.
Researchers have developed a new synthetic skin, made of hydrogels, to study how mosquitoes transmit deadly diseases. The hydrogel system can mimic different blood vessel patterns, allowing for more consistent testing and analysis. This breakthrough may help identify ways to prevent the spread of disease.
A sunlight-powered porous hydrogel inspired by loofahs can rapidly absorb and release purified water. The material has the potential to meet a person's daily demand, regardless of light conditions.
Researchers at Princeton University have developed a new solar absorber gel technology that can filter pollutants from water, producing almost fourfold more filtration rate than its predecessor. The device can provide enough clean water to meet daily demand in many parts of the world.
Researchers have created a set of computational models to predict the structure, mechanical properties, and functional performance outcomes of granular hydrogels. The new framework could make it easier to design materials that can be injected for different types of applications.
A new antibacterial spray and coating can kill antibiotic-resistant bacteria, reducing the risk of infection in wounds and medical devices. The innovative material has been shown to be effective against MRSA and other resistant bacteria, offering a promising solution to combat antibiotic resistance.
Researchers developed an injectable biomimetic hydrogel composite loaded with stem cells that promotes regenerative healing in animal models of Crohn's perianal fistulas. The treatment reduced fistula size by six-fold compared to surgery, offering a potential new paradigm for treating this condition.
Researchers at Hokkaido University developed a hybrid hydrogel combining natural squid tissues with synthetic polymers, exhibiting hierarchical anisotropy and toughness.
Engineers create OCTOPUS device to grow organs-in-a-dish, achieving higher levels of maturity than traditional methods. The device allows for more mature organs with complex cell relationships, providing valuable tools for studying human organ development.
Researchers developed an injectable hydrogel that inhibits common bacteria and promotes tissue regrowth, treating infections around prosthetics. The gel has a porous structure, excellent injectability, and rapid self-healing properties.
A new type of electrically conductive hydrogel scaffold has been developed to support brain cell growth and differentiation. The scaffold mimics the soft conditions of brain tissue and enables the creation of implantable biohybrid BCIs that integrate with a patient's brain tissue.
New expansion microscopy methods, dubbed Magnify, allow researchers to observe nanoscale biological structures with standard microscopes. The protocol retains biomolecules intact, enabling simultaneous imaging of proteins, lipids, and carbohydrates.
A team of researchers has created a new method for fabricating nanodevices by shrinking hydrogels to create 3D patterns. This technique uses ultrafast two-photon lithography and can produce high-resolution patterns up to 13 times larger than the original size, enabling the creation of complex nanostructures.
A team of scientists from TIBI, UIC, and POSTECH has elucidated key points on how cartilage generation is facilitated and alternative bone formation can be avoided. They found optimal conditions for better cartilage regeneration while reducing excessive cartilage formation using human mesenchymal stem cells.
A new injectable hydrogel has been developed to rapidly stop bleeding from traumatic wounds. The material becomes solid when injected into the body and can be easily washed away with a cold saline solution.
Researchers have created a hydrogel-based material that can absorb up to three times more water-based liquid than traditional paper towels. The gel sheets also show promise in absorbing thick liquids, such as blood and syrup, with high efficiency and stability.
Researchers at UNSW Sydney have successfully induced a gastrulation-like event in human pluripotent stem cells, mimicking the early stages of embryonic development. This breakthrough could lead to new approaches for studying human development and creating personalized body tissue or organs using hydrogel materials.
A new method for creating freestanding hydrogel lumens that can accurately replicate blood vessels and facilitate vasodilation research. This approach allows researchers to study vasodilation in a more efficient and effective manner, overcoming limitations of existing methods.
Researchers developed a customizable, strontium-loaded scaffold that promotes wound healing by stimulating gingival fibroblast activity. The scaffold increased cellular activity of isolated cells while showing minimal toxicity over four days.
Researchers from City University of Hong Kong developed a new ultra-stable hydrogen evolution reaction electrocatalyst based on two-dimensional mineral gel nanosheets. The catalyst exhibits excellent electrocatalytic activity and long-term durability, with an overpotential of only 38.5 mV at 10 mA cm−2.
A new non-hormonal gel blocks sperm by reinforcing cervical mucus barrier, demonstrating high effectiveness in reducing uterine sperm numbers. The gel has shown a 98% average decrease in sperm numbers compared to untreated control animals, making it a promising alternative to existing contraceptives.