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Untangling The Protein Folding Problem

Protein folding research is undergoing explosive growth, revealing secrets of spontaneous self-assembly process, according to an editorial by Jay Winkler and Harry Gray. The study focuses on chemical kinetics and includes real-time observations, advancing efforts to design new drugs and decode genetic information.

SourceAmerican Chemical Society·JournalAccounts of Chemical Research·DateNov 12, 1998

Engineering New Enzymes

Researchers successfully engineered a hybrid enzyme with improved substrate specificity, demonstrating the potential of recombining subdomains to generate novel functions. The study presents a method for generating hybrid genes by combining subdomain segments from diverse proteins.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateSep 2, 1998

Rewiring The Brain

A protein called osteogenic protein-1 (OP-1) may speed the recovery of stroke patients by rewiring damaged brain cells. The experiment used rats and showed that OP-1 helped them recover lost movement in their limbs quickly, outperforming those in a control group.

SourceNew Scientist·JournalThe New Scientist·DateJun 17, 1998

Bless You

Scientists have found that parts of the protein shell of the common cold virus flap open in a motion called "breathing", which can be stifled by compounds that stop viruses from infecting cells. This discovery could lead to rapid screening methods for antiviral drugs.

SourceNew Scientist·JournalThe New Scientist·DateJun 17, 1998