Researchers identified a more selective iron chelator compound named adaptaquin that blocks specific iron-containing enzymes without affecting total iron. This compound may provide neuroprotection after a brain hemorrhage event by blocking a protein called ATF4, which drives cell death in neurons.
A study by University of Granada researchers found that maternal DHA supplementation enhances fetal iron metabolism, improving iron reserves and preventing anemia-related complications. The research involved 110 healthy pregnant women who received either a balanced diet or a balanced diet with omega-3 supplements.
Researchers developed a new approach to designing insulin-based pharmaceuticals using self-assembling nano-insulin. This method could lead to more personalized medications with fewer side effects for Type 1 Diabetes patients.
A study published in Gut journal found that oral and intravenous iron replacement therapies alter the gut microbiota significantly, particularly in Crohn's disease patients. These changes may lead to unstable bacterial ecosystems and increased risk of disease flares.
Concentrations of iron similar to those delivered through standard treatments can trigger DNA damage within 10 minutes, when given to cells in the laboratory. Researchers from Imperial College London suggest that standard treatment dosages may be causing cell damage, highlighting the need for careful consideration of iron levels.
Researchers have created a new material using quantum dots of iron on boron nitride nanotubes, which can replace semiconductors in wearable technology. This new material enables transistors to shrink and reduces heat generation, making it suitable for flexible and efficient wearable electronics.
Researchers found that iron fertilization in one area can inhibit growth in others, highlighting the complexity of ocean nutrient cycles. This study challenges the idea that fertilizing oceans with iron could be a major force in spurring and maintaining ice ages.
Researchers have discovered a new class of catalysts that use iron-nitrogen compounds in graphene, achieving levels of activity comparable to platinum-based catalysts. The purification process allows for the creation of exclusively FeN4 centres, which provide high catalytic efficiency even without promoters.
Research from the Buck Institute suggests that excess iron impairs cellular recycling in Parkinson's disease, resulting in toxic oxidative stress. The study highlights the importance of maintaining a healthy balance of iron within cells to prevent neurodegeneration.
Researchers at Arizona State University have identified the natural environment of formation for toxic clay antibacterial properties. The discovery reveals how chemically reduced iron tricks bacterial cells into opening their walls, followed by aluminum, which propels the cell wall open and poisons the cell.
A study by McGill University researchers proposes using metal powders as a viable alternative to fossil fuels for generating electricity and powering transportation. The use of metal powders in external-combustion engines could provide a zero-carbon solution with recyclable fuels that store clean primary energy.
Research shows that inadequate prenatal iron intake can exert subtle effects on infant brain development. Higher dietary iron intake is associated with greater complexity and maturity of cortical gray matter, while lower intake is linked to lesser complexity and more immaturity.
Scientists have created a new variety of iron oxide with a hexagonal structure that remains stable even when multiple layers are added. The material exhibits unusual magnetic properties, visible at room temperature, in contrast to traditional iron oxides.
Researchers extend catalogue of material properties with first liquid measurements under extreme conditions. The study suggests that only about 1.2% of the core is carbon, with other light elements present.
A new study found a link between abrupt ocean warming at the end of the last ice age and low-oxygen conditions that led to vast marine dead zones. Warming surface temperatures triggered loss of oxygen in the North Pacific, raising concern that similar events will occur again as oceans warm.
A new study finds a link between abrupt ocean warming and low-oxygen conditions that led to vast marine dead zones in the North Pacific. The researchers discovered a clear connection between two prehistoric intervals of abrupt ocean warming that ended the last ice age, resulting in an increase in diatom production and subsequent hypoxia.
A study analyzed data from 688,183 recipients of IV iron products and identified a higher risk of anaphylaxis with certain formulations, including iron dextran. The researchers found that the cumulative risk of anaphylaxis was highest with iron dextran and lowest with iron sucrose.
Researchers at Empa have created a 'fool's gold' battery using magnesium and pyrite, offering safe, durable, and affordable storage. The battery has withstood 40 charging cycles without compromising performance.
A team of scientists has found evidence of iron-rich dust from 300 million years ago, which suggests that atmospheric dust acted as a fertilizer for life. The discovery provides new insights into the biogeochemical impacts of iron on the oceans and the climate system during the late Paleozoic era.
A new study reveals that hepcidin, a protein regulating iron absorption, can inhibit the body's ability to absorb iron supplements in quantities necessary and desirable. The researchers suggest waiting longer between doses may improve iron absorption efficiency and reduce side effects.
This week in BMJ Case Reports highlights the risks of accidental overdosing on herbal medicines, severe iron deficiency associated with heavy head lice infestation, and a rare complication involving a hair pin pierced through a child's kidney.
Researchers found that nanoparticles can evade the human immune system by changing their sugar coating, making them more visible during MRI imaging. This breakthrough could lead to the development of new medicines to target tumors.
Planetary scientist Shoshanna Cole discovered signs of acid fog on Mars, which formed when acidic vapors dissolved minerals and created gel-like cement. The phenomenon was observed in the Watchtower Class outcrops on Husband Hill, indicating a change in the environment billions of years ago.
A new class of oral medications, HIF-PHIs, stimulates red blood cell production by mimicking a low-oxygen state. Promising results were achieved in phase 2 clinical trials, showing improved hemoglobin levels and reduced anemia in kidney disease patients.
Scientists have discovered unmistakable signs of oxygen in ancient iron-bearing rocks from the ocean floor, dating back 3.23 billion years. The findings suggest that cyanobacteria, primitive photosynthetic organisms, were responsible for liberating oxygen, marking a significant milestone in Earth's history.
Harvard scientists have developed a rechargeable battery that can store electricity from renewable sources like solar and wind power. The new technology uses non-toxic, abundant elements dissolved in water solution, making it safer and cheaper than traditional batteries.
Researchers have found that platinum nanoparticles sitting on cheap metal oxide materials convert carbon monoxide into carbon dioxide. The chemical reactions occur due to the interplay between platinum particles and the iron-oxide surface, making them efficient. This new knowledge can be used to create better catalysts.
Scientists discovered microbes in Kabuno Bay that oxidize iron through a unique photosynthesis process, depositing large iron formations. This finding supports the theory that microorganisms played a key role in shaping Earth's chemistry and evolution of life.
A study in a malaria-endemic region found that daily iron supplementation during pregnancy did not increase the risk of malaria, but resulted in increased birth weight and improved fetal outcomes. The authors suggest that universal iron supplementation may outweigh potential risks in low- and middle-income countries.
The American College of Physicians recommends policies for the use of telemedicine in primary care settings, aiming to improve access to care while balancing benefits and risks. The position paper offers more than a dozen policy statements and recommendations for utilization and reimbursement.
A new MIT study finds that large seasonal changes in desert dust can dramatically affect surface phytoplankton, which rely on iron as a main nutrient for growth. The team determined that iron has a very short residence time in ocean waters, lasting only six months before sinking into the deep ocean.
A team of marine researchers has discovered a three-way conflict between algae, bacteria, and vitamin B12 in the frigid waters off Antarctica. The competition for iron and vitamins has significant implications for understanding globally significant food webs of the Southern Ocean.
Researchers found that teeth can provide a chronological record of exposure to chemicals, including iron, from fetal development. This technology can help track the impact of pollution on health globally and potentially link early life exposures to neurodegenerative diseases like Parkinson's and Alzheimer's.
Researchers at Michigan State University have developed a new 3-D model of a giant star's last moments, which could help explain how these stars explode. The model addresses previous limitations, including the shape of the star and the lack of fuel source, paving the way for a deeper understanding of supernova mechanisms.
Researchers found iron-laden microglia in specific brain regions of Alzheimer's patients, which could aid in earlier diagnosis and monitoring using advanced MRI techniques. The study suggests a new suspect for the disease, contradicting the long-held hypothesis that amyloid plaques are the primary cause.
Researchers have discovered that iron regulatory proteins play a crucial role in fighting off infection by controlling iron levels. The study found that mice lacking these proteins died when infected with the Salmonella bacteria, highlighting their importance in immune defense.
A new study reveals that chemical-laden plumes from hydrothermal vents can be traced across the Pacific for over 4,000 kilometers and impact global ocean chemistry. The iron transported by these plumes has the potential to serve as a key life-sustaining micro-nutrient in the surface oceans of Antarctica.
Research from the University of Washington finds that seafloor hot springs provide a significant source of iron to the world's oceans. The dissolved metals are carried by deep-sea currents for decades, supporting phytoplankton growth and impacting global ocean chemistry.
Clostridium difficile, the most common cause of hospital-acquired diarrhea, tightly controls its intracellular iron levels to avoid DNA damage. The pathogen has multiple systems for importing ferrous iron compounds, which are more critical in anaerobic conditions.
A recent study published in PNAS reveals that half of the iron in banded iron formations originated from ancient bacteria metabolizing iron two and a half billion years ago. The findings provide new insights into the evolution of our planet and the origins of life, with significant implications for fields like mining and astrobiology.
Medical laser technologies hold promise for various applications, including iron deficiency screening, breast cancer treatment, glioblastoma multiforme surgery, nasal airway obstruction relief, and varicose vein treatment. However, their translation into clinical practice is hindered by multiple barriers that need to be overcome.
Researchers have discovered a soil microbe that mobilizes an "iron shield" to block the uptake of toxic arsenic in rice. The microbe, EA106, forms a plaque on the surface of roots that competes with arsenic, effectively blocking its pathway. Inoculations with EA106 improved iron uptake and reduced arsenic accumulation in plants.
Researchers discovered a molecular mechanism that contributes to age-related macular degeneration due to excessive iron accumulation in retinal cells. Excessive iron impairs the processing of inflammatory RNAs, leading to inflammasome-mediated cell death.
New research finds that pH lowering of municipal water supplies can increase particulate lead levels due to corrosion of cast iron mains. The study suggests that future strategies to reduce lead in drinking water may require infrastructure upgrades or iron control measures.
Researchers have discovered a key link between superconductivity and structure in iron arsenide compounds, which could potentially lead to higher-temperature superconductivity. Under pressure, the compound undergoes a structural change that leads to a loss of superconducting ability.
A study examining umbilical cord clamping and neurodevelopment found that delayed cord clamping was associated with higher scores in fine-motor and social skills in children at age 4, especially in boys. The results suggest positive effects from delayed cord clamping without any adverse effects on overall IQ or behavior.
A four-year follow-up study of 263 children found that delayed cord clamping (DCC) was associated with improved fine motor skills, particularly in boys. The study did not find a significant impact on IQ or overall development.
Researchers have discovered that carbonates in the deep mantle can contain significant amounts of iron, contrary to previous thought. The study found that these minerals undergo a spin transition under pressure, redistributing iron between them.
A systematic review highlights how anaemia can distort the regular method of diabetes diagnosis and lead to false diagnoses based on glycated haemoglobin (HbA1c). The study found that iron deficiency and anaemia can increase HbA1c values without corresponding rises in blood glucose, making diabetes diagnosis unreliable.
Researchers have identified a mechanism allowing E. coli to thrive in inflammatory bowel disease patients by inhibiting myeloperoxidase and regulating iron levels. This discovery may lead to new treatments targeting enterobactin-based drugs or alleviating inflammatory pathways.
Researchers have uncovered new insights into the structural controls of fluid pathways in an active rift system, with potential implications for geothermal exploration. The study focuses on Aluto volcano, a major source of geothermal energy in Ethiopia's Rift Valley.
Scientists have developed a new X-ray imaging technique to better understand lithium-ion rechargeable batteries containing iron fluoride. The technique allows for precise visualization and measurement of chemical changes at the nanoscale, enabling improved understanding of electrochemical reactions in these batteries.
The US Preventive Services Task Force has updated its recommendations on iron supplementation and screening in pregnant women, finding that routine iron supplementation during pregnancy may reduce the incidence of iron deficiency and anemia. In contrast, new hepatitis C treatments show promise but may exceed insurers' willingness to pa...
Scientists have discovered 30 new types of heat-beater beans that can thrive in drastic weather extremes, offering a climate-friendly option for farmers. The development of these heat-defying beans is a landmark result of urgent efforts to adapt crops to environmental stresses and could save the 'meat of the poor' from global warming.
Researchers at Children's Hospital Los Angeles have found that liver MRI is more accurate than biopsy in determining total body iron balance. The study suggests that liver MRI can be a safer and less painful alternative to liver biopsy, which has high sampling variability and can cause bleeding.
Researchers found that iron vaporization at high pressures can create an iron-rich rain that blankets the forming Earth, explaining the iron pockets in the mantle. This process challenges traditional core formation theories and changes our interpretation of geochemical data.
Scientists have discovered iron-oxidizing bacteria living near sulfur-rich black-smoker hydrothermal vents along the Mid-Atlantic Ridge. These unique chemosynthetic communities utilize iron as an energy source and are highly evolved to thrive in environments with abundant iron.
Researchers at Houston Methodist have developed magnetic nanoparticles that can destroy blood clots 100 to 1,000 times faster than a commonly used clot-busting technique. The nanoparticles are coated in albumin and loaded with the drug tPA, allowing it to reach the clot more effectively.
Aalto University researchers have successfully created a cost-effective and efficient electrocatalyst made of iron and carbon, replacing traditional platinum-based systems. The new material reduces losses and makes the process economically viable, addressing challenges in energy storage.
Scientists have uncovered a key factor driving iron's unique thermal behavior, revealing a synergy between magnetism and atomic vibrations that increases the metal's stability at high temperatures. This breakthrough could lead to more accurate predictions of steel properties and enable the development of new, stronger alloys.