Articles tagged with Iron
Low-dose iron supplements significantly reduced time to recover from hemoglobin decrease in donors with low or high ferritin levels. Without iron, most participants took over 168 days to recover their iron stores. Regular blood donation leads to progressive iron loss and anemia, emphasizing the importance of prompt recovery.
A National Institutes of Health-funded study found that iron supplementation significantly reduced the time to recover lost iron and hemoglobin after blood donation. The study, supported by NHLBI, showed that donors taking iron supplements recovered lost iron more rapidly than those not receiving supplements.
Scientists at EMBL and Heidelberg University Clinic have discovered a new way to starve pathogens of iron, using the immune system's TLR2 and TLR6 molecules. This finding offers an alternative approach to treatments for anaemia of chronic disease, which affects chronically ill patients.
A new study by scientists at Woods Hole Oceanographic Institution reveals that the deep ocean is a major source of dissolved iron in the central Pacific Ocean. The research found that hydrothermal vents and sediments thousands of meters below the sea surface are the primary sources of iron, contradicting previous assumptions.
Scientists from Carnegie Institution have made a groundbreaking discovery that resolves the long-standing debate on how metals become less conductive when heated. Their work reveals that the missing piece of the traditional theory explaining this phenomenon was needed to complete the puzzle for generating Earth's magnetic field.
Researchers capture asteroid magnetic field moments, revealing extended lifetimes and creating mechanisms similar to the Earth's own magnetic field. Ancient meteorites provide a cosmic archaeological mission, shedding light on the magnetic history of asteroids and their impact on the Earth's core future.
A study in C. elegans found that excess iron promotes aging by causing dysfunction and malfolding of proteins implicated in the aging process. Treating worms with a metal chelator slowed age-related accumulation of iron, extending lifespan and healthspan.
Researchers at UCLA have found that a deficiency of the hormone hepcidin makes people with iron overload disease susceptible to Vibrio vulnificus infections. A medical form of hepcidin, minihepcidin, has been shown to cure the infection by restricting bacterial growth.
Researchers at Sandia National Laboratories have discovered that iron's opacity plays a significant role in regulating energy transfer within the sun. By creating conditions similar to those found inside the sun, the team was able to measure the opacity of iron and close a theoretical gap in the Standard Solar Model.
Researchers have found iron-based catalysts for diazo compound transformations, offering a sustainable alternative to precious metals. These iron complexes exhibit unique advantages in specific reactions, including cyclopropanation and enantioselectivity.
Researchers have successfully created metal-organic frameworks that can stably store and slowly release nitric oxide, a key player in biological signaling pathways. This breakthrough could lead to new approaches for treating infections and heart conditions, as well as potential applications in medical therapies.
Researchers at Vienna University of Technology have redefined the atomic structure of magnetite, a crucial component in electronic devices and medical applications. The study reveals that the surface of magnetite is governed by missing iron atoms, leading to an efficient catalyst for chemical reactions.
A new model proposes that iron carbide could explain the anomalously slow S waves, thus eliminating the need to invoke partial melting. This would imply that as much as two-thirds of the planet's carbon is hidden in its center sphere.
Researchers have identified genetic factors associated with increased iron and zinc levels in chickpea seeds, a staple food in developing countries. The findings support the development of molecular breeding strategies to enhance micronutrient content in chickpea cultivars.
Researchers identify defects in iron pyrite material as the source of inefficiency. The study provides hope for improving this promising material to make inexpensive yet efficient solar cells. By understanding the causes of this problem, scientists can design solutions to overcome it.
Late-breaking clinical studies presented at ASN Kidney Week 2014 highlight significant advances in kidney care, including the reduction of disparities in transplant referrals through a community-based intervention. Additionally, new treatments for End-Stage Renal Disease (ESRD) have shown promising results, such as ferric citrate's abi...
The Ferric Citrate OLE study demonstrated the iron-based phosphate binder's long-term safety and efficacy in managing elevated serum phosphorus levels. Patients treated with Ferric Citrate showed improvements in laboratory parameters, including reduced serum phosphorus levels and increased hemoglobin
A new study reveals that iron fertilization in the Southern Ocean may reduce the biological carbon pump's ability to transport carbon dioxide into the deep ocean. This process, which draws carbon dioxide from the atmosphere into the sea, is crucial for mitigating climate change.
Virginia Tech researchers found that school lunches have greater nutritional quality compared to packed lunches. School lunches were lower in energy and iron but higher in protein and fiber. The study suggests promoting healthier options in packed lunches through nutrition education programs.
Researchers found that dietary iron plays a crucial role in regulating the liver's circadian clock, which can disrupt blood glucose levels. Eating high-iron foods at night may exacerbate this issue for shift workers, increasing the risk of metabolic disorders. More research is needed to determine optimal iron intake for shift workers.
Ines Ehrnstorfer's research reveals the structural basis of DMT1's selective iron and manganese binding. The study shows that mutations weaken ion binding and transport in human DMT1, providing a basis for developing inhibitors to treat iron storage diseases.
Washington State University researchers develop a new catalyst using inexpensive iron and rare palladium to remove oxygen from plant-based materials, improving biofuel production. The combination increases activity, stability, and selectivity, reducing costs and increasing yields.
A study by researchers at the UC Davis MIND Institute found that mothers of children with autism are less likely to report taking iron supplements before and during pregnancy. The risk is five-fold greater in children whose mothers had low supplemental iron and other risk factors for delivering a child with ASD.
Researchers in Australia found that airborne dust particles stimulate inflammatory responses in airway cells, contributing to asthma development and worsening. The study suggests larger particles derived from dust may have important adverse effects on human health.
Researchers have adapted a biomedical technique to study ocean organisms, identifying and measuring proteins to understand biochemical reactions. The study reveals how microbes respond to environmental cues and ecosystem changes over large regions.
Researchers have adapted a biomedical technique to study the ocean, revealing how single-celled marine organisms and ecosystems are operating. By measuring proteins, scientists can identify biochemical reactions happening within organisms and diagnose how the oceans respond to pollution and climate change.
A study found that intravenous iron supplementation improved functional capacity and quality of life in heart failure patients with iron deficiency, reducing hospital admissions for worsening heart failure. The treatment also showed benefits in measures of functional status and quality of life.
An experimental drug has demonstrated potential as a first treatment for anemia of inflammation, regulating blood's iron supply and maintaining its transport. The treatment, lexaptepid pegol, inactivates hepcidin hormone production, improving iron levels without interfering with the immune response.
Baicalin inhibits iron accumulation after substantia nigra injury by down-regulating divalent metal transporter 1 and increasing ferroportin 1 expression. This study suggests baicalin as a potential therapeutic agent for Parkinson's disease prevention.
A study of 158 pregnant teenagers found nearly half engaged in pica behaviors, such as consuming ice and starches, which are also associated with lower iron levels. This can lead to anemia, premature births, and low birth weights, posing a significant risk to infant mortality rates.
A new trial in Bangladesh aims to assess the effect of lactoferrin on treating iron deficiency anemia in pregnancy. If successful, it could lead to cost-efficient improvements in global newborn health and development.
Researchers at Lund University discovered how Haemophilus influenzae bacteria can share iron with each other, increasing their chances of survival and potentially creating new vaccine targets. This interaction has significant implications for the development of vaccines and treatments for respiratory infections.
Researchers created a model showing how Mercury's core dynamics contribute to its unusual magnetic field, which is three times stronger in the north than south. This finding indicates that planets have multiple ways of generating a magnetic field.
A medication called ferric citrate may reduce the need for dialysis patients to take multiple drugs that treat complications related to kidney disease. Ferric citrate binds phosphorus, increases iron stores, and decreases the need for iron and anemia medications, leading to fewer hospitalizations.
The Zerenex PERFECTED study demonstrated a highly statistically significant change in serum phosphorus, increases in serum ferritin and transferrin saturation, and significant reductions in IV iron and ESA usage. This could lead to significant pharmaco-economic benefits and improved patient care.
Dr. Tomas Ganz is recognized for his pioneering work on iron homeostasis and the discovery of the hormone hepcidin, which plays a crucial role in regulating iron metabolism. His research has significant implications for understanding and treating iron deficiency anemia and inflammation.
Researchers at Kansas State University have found that bacteria can acquire iron from the environment using tiny protein loops on their surface. These protein loops are similar to fingers and can open or close to grab iron molecules, allowing the bacteria to establish an infection.
Researchers at Case Western Reserve University identified a promising new pathway to disabling bacterial infection: blocking bacteria's access to iron in the body. They found that bacteria can feed on iron supplied by both bacterial and mammalian siderophore, allowing them to proliferate and make the host ill.
Scientists have found that the largest source of iron in the North Atlantic comes from dust blowing in from the Sahara desert, but other sources such as sediments also play a significant role. This discovery has important implications for understanding the carbon cycle and past climate change.
A team of researchers at the University of Wisconsin-Milwaukee has developed a method to produce graphene ribbons with widths as low as three nanometers, transforming them into semiconductors with tunable electrical properties. This breakthrough could lead to the creation of nano-devices and atomic-scale components made from graphene.
Researchers at NREL created high-performance, binder-free electrodes using carbon-nanotube-based materials to improve battery life and performance. The technology has attracted interest from industry and is being licensed for volume production.
A WUSTL scientist has developed a drug delivery system that exploits bacterial siderophores to target specific pathogens, potentially reviving abandoned antibiotics and making it harder for bacteria to develop resistance. The system uses tiny Trojan horses linked to siderophore molecules to smuggle antibiotics into bacterial cells.
Empa researchers have developed a microstructure that gathers sunlight on the photoelectrode surface, allowing it to absorb all the energy in the beam. This innovative structure is inspired by the eyes of moths, which collect as much light as possible while reflecting as little as possible.
Researchers have identified abnormal brain iron levels in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD), which may help improve diagnosis and treatment. The study suggests that brain iron absorption into the brain is abnormal in ADHD, even when blood iron levels are normal.
Researchers have created composite particles that can be injected into patients and guided by magnetic fields, allowing for improved detection of diseases. The nanoconstructs, made up of thousands of iron oxide particles, can be heated to kill malignant tissues or trigger the release of drugs at specific sites.
A Cornell-led study describes an important role of a protein called OPT3 in maintaining balance of essential micronutrient iron in plants. The research found that OPT3 transports iron and regulates its concentration to partition cadmium away from edible plant parts.
A recent study reveals that grain legume crops are a valuable source of essential micronutrients, including iron, zinc, selenium, magnesium, manganese, copper, and nickel. The research found that these crops can provide up to 100% of the recommended daily allowance for certain micronutrients per serving.
A study published in Acta Obstetricia et Gynecologica Scandinavica found that iron supplements improved energy, physical function, and social function in women with heavy menstrual bleeding. After one year of treatment, anemic women showed significant increases in these areas compared to non-anemic women.
A study suggests that warming climates can indirectly increase CO2 levels in the atmosphere by reducing iron and silicon availability in ocean waters. This is particularly significant in the southern ocean and equatorial Pacific, which play a crucial role in regulating atmospheric CO2.
Research from Oregon State University found that exposure to iron pipes and steel rebar can alter the magnetic field around fish, affecting their ability to navigate. The study suggests that stabilizing the magnetic field by using alternative materials in hatcheries may help produce better yields of fish.
A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production. Erythroferrone suppresses hepcidin, allowing more iron to be made available for red blood-cell production and potentially treating iron disorders.
A metal-organic framework (MOF) has been found to catalyze the conversion of ethane from natural gas into ethanol, a process previously thought to require complex biological steps. The discovery showcases the potential for laboratory-made materials to mimic nature's processes.
Grand Challenges Canada announces $12 million investments in global health projects aiming to reduce maternal, newborn and child mortality. Four Canadian-based projects will share $2.6 million in scale-up grants.
Researchers at Argonne National Laboratory have discovered a previously unknown phase in iron arsenides, which could resolve a long-standing debate about the origin of nematic order. The new magnetic phase exhibits four-fold symmetry near the onset of superconductivity, contradicting orbital theories and supporting a magnetic explanation.
A UK team discovered that summer meltwaters from ice sheets are rich in bioavailable iron, which boosts phytoplankton growth and captures carbon, thus buffering the effects of global warming. The researchers estimate that the flux of bioavailable iron associated with glacial runoff is between 400,000 and 2,500,000 tonnes per year.
A new study suggests that a natural limiting switch exists in ocean systems, preventing the development of unchecked hypoxic areas. This cutoff switch is triggered by the formation of iron sulfides when oxygen levels approach zero.
Researchers are exploring a new therapy to eliminate the major risk of minor bleeding after stroke, focusing on diabetic patients who are at higher risk. The treatment involves an iron chelating agent that can remove excess iron from the brain, reducing damage and promoting recovery.
Researchers have modeled water properties at the nanoscale, revealing surprising characteristics that can benefit various technological applications. The study's findings may lead to advancements in biomedical imaging, particularly Magnetic Resonance Imaging (MRI), by optimizing contrast agents and improving image quality.
A new study led by Harvard School of Public Health finds that elevated CO2 concentrations will significantly reduce zinc and iron concentrations in crops providing a large share of the global population's dietary intake. The reduction poses a major health threat, with an estimated loss of 63 million life years annually from malnutrition.
Researchers found that high CO2 levels reduce zinc and iron content in key crops like wheat, rice, and soybeans. Nutrient deficiencies affect at least 2 billion people worldwide, highlighting the need for more research on crop responses to elevated atmospheric CO2.