Researchers found that dietary iron plays a crucial role in regulating the liver's circadian clock, which can disrupt blood glucose levels. Eating high-iron foods at night may exacerbate this issue for shift workers, increasing the risk of metabolic disorders. More research is needed to determine optimal iron intake for shift workers.
Ines Ehrnstorfer's research reveals the structural basis of DMT1's selective iron and manganese binding. The study shows that mutations weaken ion binding and transport in human DMT1, providing a basis for developing inhibitors to treat iron storage diseases.
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Washington State University researchers develop a new catalyst using inexpensive iron and rare palladium to remove oxygen from plant-based materials, improving biofuel production. The combination increases activity, stability, and selectivity, reducing costs and increasing yields.
A study by researchers at the UC Davis MIND Institute found that mothers of children with autism are less likely to report taking iron supplements before and during pregnancy. The risk is five-fold greater in children whose mothers had low supplemental iron and other risk factors for delivering a child with ASD.
Researchers in Australia found that airborne dust particles stimulate inflammatory responses in airway cells, contributing to asthma development and worsening. The study suggests larger particles derived from dust may have important adverse effects on human health.
Researchers have adapted a biomedical technique to study ocean organisms, identifying and measuring proteins to understand biochemical reactions. The study reveals how microbes respond to environmental cues and ecosystem changes over large regions.
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Researchers have adapted a biomedical technique to study the ocean, revealing how single-celled marine organisms and ecosystems are operating. By measuring proteins, scientists can identify biochemical reactions happening within organisms and diagnose how the oceans respond to pollution and climate change.
A study found that intravenous iron supplementation improved functional capacity and quality of life in heart failure patients with iron deficiency, reducing hospital admissions for worsening heart failure. The treatment also showed benefits in measures of functional status and quality of life.
An experimental drug has demonstrated potential as a first treatment for anemia of inflammation, regulating blood's iron supply and maintaining its transport. The treatment, lexaptepid pegol, inactivates hepcidin hormone production, improving iron levels without interfering with the immune response.
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Baicalin inhibits iron accumulation after substantia nigra injury by down-regulating divalent metal transporter 1 and increasing ferroportin 1 expression. This study suggests baicalin as a potential therapeutic agent for Parkinson's disease prevention.
A study of 158 pregnant teenagers found nearly half engaged in pica behaviors, such as consuming ice and starches, which are also associated with lower iron levels. This can lead to anemia, premature births, and low birth weights, posing a significant risk to infant mortality rates.
A new trial in Bangladesh aims to assess the effect of lactoferrin on treating iron deficiency anemia in pregnancy. If successful, it could lead to cost-efficient improvements in global newborn health and development.
Researchers at Lund University discovered how Haemophilus influenzae bacteria can share iron with each other, increasing their chances of survival and potentially creating new vaccine targets. This interaction has significant implications for the development of vaccines and treatments for respiratory infections.
Researchers created a model showing how Mercury's core dynamics contribute to its unusual magnetic field, which is three times stronger in the north than south. This finding indicates that planets have multiple ways of generating a magnetic field.
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The Zerenex PERFECTED study demonstrated a highly statistically significant change in serum phosphorus, increases in serum ferritin and transferrin saturation, and significant reductions in IV iron and ESA usage. This could lead to significant pharmaco-economic benefits and improved patient care.
A medication called ferric citrate may reduce the need for dialysis patients to take multiple drugs that treat complications related to kidney disease. Ferric citrate binds phosphorus, increases iron stores, and decreases the need for iron and anemia medications, leading to fewer hospitalizations.
Dr. Tomas Ganz is recognized for his pioneering work on iron homeostasis and the discovery of the hormone hepcidin, which plays a crucial role in regulating iron metabolism. His research has significant implications for understanding and treating iron deficiency anemia and inflammation.
Researchers at Kansas State University have found that bacteria can acquire iron from the environment using tiny protein loops on their surface. These protein loops are similar to fingers and can open or close to grab iron molecules, allowing the bacteria to establish an infection.
Researchers at Case Western Reserve University identified a promising new pathway to disabling bacterial infection: blocking bacteria's access to iron in the body. They found that bacteria can feed on iron supplied by both bacterial and mammalian siderophore, allowing them to proliferate and make the host ill.
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A team of researchers at the University of Wisconsin-Milwaukee has developed a method to produce graphene ribbons with widths as low as three nanometers, transforming them into semiconductors with tunable electrical properties. This breakthrough could lead to the creation of nano-devices and atomic-scale components made from graphene.
Scientists have found that the largest source of iron in the North Atlantic comes from dust blowing in from the Sahara desert, but other sources such as sediments also play a significant role. This discovery has important implications for understanding the carbon cycle and past climate change.
Researchers at NREL created high-performance, binder-free electrodes using carbon-nanotube-based materials to improve battery life and performance. The technology has attracted interest from industry and is being licensed for volume production.
A WUSTL scientist has developed a drug delivery system that exploits bacterial siderophores to target specific pathogens, potentially reviving abandoned antibiotics and making it harder for bacteria to develop resistance. The system uses tiny Trojan horses linked to siderophore molecules to smuggle antibiotics into bacterial cells.
Empa researchers have developed a microstructure that gathers sunlight on the photoelectrode surface, allowing it to absorb all the energy in the beam. This innovative structure is inspired by the eyes of moths, which collect as much light as possible while reflecting as little as possible.
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Researchers have identified abnormal brain iron levels in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD), which may help improve diagnosis and treatment. The study suggests that brain iron absorption into the brain is abnormal in ADHD, even when blood iron levels are normal.
Researchers have created composite particles that can be injected into patients and guided by magnetic fields, allowing for improved detection of diseases. The nanoconstructs, made up of thousands of iron oxide particles, can be heated to kill malignant tissues or trigger the release of drugs at specific sites.
A Cornell-led study describes an important role of a protein called OPT3 in maintaining balance of essential micronutrient iron in plants. The research found that OPT3 transports iron and regulates its concentration to partition cadmium away from edible plant parts.
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A recent study reveals that grain legume crops are a valuable source of essential micronutrients, including iron, zinc, selenium, magnesium, manganese, copper, and nickel. The research found that these crops can provide up to 100% of the recommended daily allowance for certain micronutrients per serving.
A study published in Acta Obstetricia et Gynecologica Scandinavica found that iron supplements improved energy, physical function, and social function in women with heavy menstrual bleeding. After one year of treatment, anemic women showed significant increases in these areas compared to non-anemic women.
A study suggests that warming climates can indirectly increase CO2 levels in the atmosphere by reducing iron and silicon availability in ocean waters. This is particularly significant in the southern ocean and equatorial Pacific, which play a crucial role in regulating atmospheric CO2.
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Research from Oregon State University found that exposure to iron pipes and steel rebar can alter the magnetic field around fish, affecting their ability to navigate. The study suggests that stabilizing the magnetic field by using alternative materials in hatcheries may help produce better yields of fish.
A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production. Erythroferrone suppresses hepcidin, allowing more iron to be made available for red blood-cell production and potentially treating iron disorders.
Grand Challenges Canada announces $12 million investments in global health projects aiming to reduce maternal, newborn and child mortality. Four Canadian-based projects will share $2.6 million in scale-up grants.
Researchers at Argonne National Laboratory have discovered a previously unknown phase in iron arsenides, which could resolve a long-standing debate about the origin of nematic order. The new magnetic phase exhibits four-fold symmetry near the onset of superconductivity, contradicting orbital theories and supporting a magnetic explanation.
A metal-organic framework (MOF) has been found to catalyze the conversion of ethane from natural gas into ethanol, a process previously thought to require complex biological steps. The discovery showcases the potential for laboratory-made materials to mimic nature's processes.
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A UK team discovered that summer meltwaters from ice sheets are rich in bioavailable iron, which boosts phytoplankton growth and captures carbon, thus buffering the effects of global warming. The researchers estimate that the flux of bioavailable iron associated with glacial runoff is between 400,000 and 2,500,000 tonnes per year.
A new study suggests that a natural limiting switch exists in ocean systems, preventing the development of unchecked hypoxic areas. This cutoff switch is triggered by the formation of iron sulfides when oxygen levels approach zero.
Researchers are exploring a new therapy to eliminate the major risk of minor bleeding after stroke, focusing on diabetic patients who are at higher risk. The treatment involves an iron chelating agent that can remove excess iron from the brain, reducing damage and promoting recovery.
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Researchers have modeled water properties at the nanoscale, revealing surprising characteristics that can benefit various technological applications. The study's findings may lead to advancements in biomedical imaging, particularly Magnetic Resonance Imaging (MRI), by optimizing contrast agents and improving image quality.
A new study led by Harvard School of Public Health finds that elevated CO2 concentrations will significantly reduce zinc and iron concentrations in crops providing a large share of the global population's dietary intake. The reduction poses a major health threat, with an estimated loss of 63 million life years annually from malnutrition.
Researchers found that high CO2 levels reduce zinc and iron content in key crops like wheat, rice, and soybeans. Nutrient deficiencies affect at least 2 billion people worldwide, highlighting the need for more research on crop responses to elevated atmospheric CO2.
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A study published in Science finds a previously unknown step in the biogeochemical process that occurs in aquifers, affecting groundwater quality and contaminant fate. Microbes breathe solid iron and sulfur, transforming them into reactive ions that impact the makeup of rocks, soil, and water.
Scientists at Ames Laboratory have observed magnetic properties typically associated with rare-earth elements in iron, when positioned between two nitrogen atoms. This discovery opens the possibility of using iron to provide both magnetism and permanence in high-strength permanent magnets.
Researchers reconstructed ancient ocean chemistry and found spontaneous occurrence of reaction sequences enabling metabolite formation. These findings suggest that metabolism predates the origin of life and evolved through early ocean conditions.
A new study from Indiana University School of Public Health-Bloomington found a strong association between heme iron consumption and coronary heart disease. Heme iron intake was shown to increase the risk for coronary heart disease by 57 percent, while nonheme iron had no such link.
Researchers found that holding babies on their mother's abdomen or chest immediately after birth does not compromise delayed cord clamping. This could lead to improved uptake and reduced risk of infant iron deficiency. The study suggests a more comfortable and bonding-friendly approach for hospitals.
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Researchers found that soil pH, iron concentrations, and total cadmium levels are excellent predictors of biologically available cadmium for plants. Increasing soil acidity can also release more cadmium into the soil, while iron oxides bind it tightly.
A systematic review found that iron supplementation boosts maximal capacity and exercise efficiency in women, even at submaximal exertion. Women who received iron had lower heart rates and higher efficiencies, especially those with initial iron deficiencies.
An international team of researchers found that deep winter mixing plays a crucial role in transporting iron to the surface, supporting phytoplankton growth and the aquatic food chain. The study highlights the unique aspects of the iron cycle and its sensitivity to climate changes.
Researchers identified a microbe that can take up electrons from minerals in soil and sediment using natural conductivity. The microbes rely on sunlight and iron to generate energy, but have developed an unusual strategy to reach the iron through naturally occurring conductive minerals.
A new study found that iron deficiency is associated with lower IQ scores and poorer higher-order thinking skills in children adopted from institutions. Children with more severe iron deficiency were more likely to have impaired cognitive functioning, regardless of their general cognitive ability.
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Researchers found relatively low iron amounts and minimal sulphur compounds in the Ghost wreck, suggesting it might not face the same preservation issues as the Vasa. Three studied ships, including the Crown, display more aggressive sulphur compounds and higher iron concentrations.
Researchers have created a hydrogel actuator that can change shape in response to changes in pH, using mussel protein-inspired chemistry. The device has the potential to be used for drug delivery and could be programmed to adopt various shapes by adjusting the placement of ions, composition, and voltage.
Scientists at Imperial College London have discovered a link between iron deficiency and an increased risk of stroke due to stickier blood cells. Iron deficiency affects around two billion people worldwide and can increase the stickiness of platelets, which initiate blood clotting.
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The NuSTAR mission has produced the first map of high-energy X-ray emissions from a supernova remnant, revealing details about the core explosion and its effects on the surrounding gas and dust. The observations provide new insights into the fundamental physics of nuclear explosions and their role in creating life's essential elements.
The discovery of the oldest known star in the Universe allows scientists to study its chemistry, providing a clearer idea of the early universe. The ancient star is around 6,000 light years from Earth and formed shortly after the Big Bang.
The study demonstrates how cyanide and carbon monoxide are safely bound to an iron atom to construct an enzyme that can generate hydrogen gas. This discovery sheds light on the unusual chemistry involved in binding small molecules to metal atoms, a crucial step towards producing hydrogen using abundant metals.
Scientists have discovered a previously unknown form of uranium that can become mobile under certain conditions, remobilizing from natural wetlands into surrounding water. Researchers found that a specific combination of organic matter, iron, and sulfide presence enables the mobility of uranium.
Researchers found no evidence of an association between iron levels and the risk of atherosclerosis, contradicting a long-held hypothesis. The study's findings carry important implications for patients with chronic kidney disease or anemia related to inflammatory disorders.
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The American College of Physicians recommends restricting red blood cell transfusions to severe anemia cases in patients with heart disease. ACP also advises against using erythropoiesis-stimulating agents in mild to moderate anemia with heart conditions due to increased risks of thromboembolic events and stroke rates.