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JCI early table of contents for March 25, 2013

Researchers characterized SUDEP in a mouse model of DS, finding that treatment with drugs reducing parasympathetic activity reduced incidence. Lymphatic vasculature also plays crucial role in cholesterol removal from arteries, with impaired lymphatic growth leading to increased cholesterol retention. A new therapeutic target is identif...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 25, 2013

Geo-engineering against climate change

A new study calculates the impact of ocean iron fertilization on carbon sequestration, finding that it is unlikely to be an effective method for reducing greenhouse gas levels. The study estimates a net sequestration rate of just 10 tonnes of carbon per square kilometer, making it a costly and inefficient solution.

SourceInderscience Publishers·JournalInternational Journal of Global Warming·DateDec 19, 2012

Iron supplements reduce ADHD in low birth weight infants

A randomized controlled trial found that iron supplements reduced behavioral problems like ADHD in low birth weight infants by 9.8 percentage points compared to those without supplementation. The study concluded that early iron supplementation has long-term health benefits for marginally low birth weight infants.

SourceUmea University·JournalPEDIATRICS·DateDec 10, 2012

Cocktail achieves superconducting boost

Scientists have synthesized a new material with promising superconducting transition temperatures of 44 Kelvins, improving upon traditional copper-based high-temperature superconductors. The material, LixFe2Se2(NH3)y, displays an intercalation of potassium or rubidium, achieving a superconducting temperature of 32K.

SourceSpringer·JournalThe European Physical Journal B·DateOct 29, 2012

From the Alps to the Deep Mantle

Two new studies provide insights into the formation of the European Alps and ancient sanukitoids. Reconstructing pre-glacial topography reveals most glacial erosion occurred in lower parts of the Alpine catchments, while aseismic creep has begun on major strike-slip faults like the North Anatolian Fault.

SourceGeological Society of America·JournalGeology·DateOct 18, 2012

Cause of diabetes may be linked to iron transport

A new study from the University of Copenhagen suggests that an increased activity of a particular iron-transport protein destroys insulin-producing beta cells, leading to type-2 diabetes. Mice without this iron transporter are protected against developing diabetes, providing potential insights into preventing the disease.

SourceUniversity of Copenhagen·JournalCell Metabolism·DateSep 20, 2012

JCI early table of contents for Sept. 10, 2012

Researchers develop a human liver-chimeric mouse model to study malaria parasites and understand human host/parasite interactions. Additionally, studies reveal the link between serum ferritin levels and insulin sensitivity, as well as the role of granulocyte-colony stimulating factor in protecting against influenza infection.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 10, 2012

Rust never sleeps

Electron mobility in iron oxide is crucial for understanding chemical reaction mechanisms, including uranium groundwater reactions and low-cost solar energy devices. The study reveals the rates of electron transport vary depending on iron oxide structure, with rates ranging from a single hop to five hops per nanosecond.

Aqueous iron interacts as strong as solid iron

Researchers developed a new method called inverse Partial Fluorescence Yield (iPFY) that allows them to examine the structure of metal ions-complexes in solution without sample damage. The study found that iron ions interact strongly with water, contradicting previous thoughts.

SourceHelmholtz Association·JournalThe Journal of Physical Chemistry Letters·DateJul 6, 2012

Myelodysplastic syndrome treated with deferasirox shows beneficial iron reduction, Moffitt says

Researchers at Moffitt Cancer Center and colleagues have tested deferasirox as a treatment for myelodysplastic syndrome (MDS), a blood-related malignancy that affects the ineffective production of blood cells. Deferasirox reduced iron levels by 23% in 53% of patients, showing promising results for this type of cancer.

SourceH. Lee Moffitt Cancer Center & Research Institute·JournalJournal of Clinical Oncology·DateJun 22, 2012

A mineral way to catalysis?

Researchers at the University of Cambridge have discovered that iron pyrite, commonly known as 'Fool's Gold', has catalytic properties. The study focused on the reactions between iron pyrite and nitrogen oxides, an extremely poisonous class of compounds produced by car engines and industrial power plants.

SourceUniversity of Cambridge·JournalPhysical Chemistry Chemical Physics·DateFeb 10, 2012

Diet counts: Iron intake in teen years can impact brain in later life

Researchers found that low iron levels in adolescence can affect the brain's physical structure, leading to changes in brain regions vulnerable to neurodegeneration. High iron levels during adolescence may also impact brain wiring and myelin production, potentially increasing the risk of diseases like Alzheimer's and Parkinson's.

SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateJan 11, 2012

News tips from the journal mBio

A recent study in the journal mBio challenges the unique E. coli protein YfeX's role in iron acquisition, finding it lacks catalytic ability to dechelate iron from heme. Meanwhile, researchers discover an unprecedented level of transference of resistance among strains and species of bacteria via plasmids containing carbapenemase genes.

Algal protein gives boost to electrochemical water splitting

Researchers have successfully created a nano-bio PEC electrode, consisting of iron oxide conjugated with a protein from blue-green algae, which is twice as efficient in water splitting as iron oxide alone. The use of phycocyanin, a light-harvesting protein, improves the electrode's ability to absorb photons and generate photocurrent.

Where does my beer come from?

Researchers at the University of Seville have developed a technique to identify beer origins using chemical patterns, distinguishing between German, Spanish and Portuguese beers with high accuracy. The model is based on variables such as aluminium, iron, and polyphenol content, providing valuable insights for the food industry.

Earth's core deprived of oxygen

A team of scientists led by Yingwei Fei found that oxygen is not a major component of the Earth's liquid outer core, contradicting previous models. The discovery has significant implications for understanding the planet's formation through accretion of dust and clumps of matter.