Articles tagged with Iron
Researchers found that hepatitis C virus infection affects hepcidin levels in patients with genotype 3a. Successful antiviral therapy was associated with decreased serum prohepcidin concentrations, suggesting a potential link between HCV and hepcidin synthesis.
Scientists have uncovered key rules governing ferritin's self-assembling nanostructure, enabling potential breakthroughs in drug development and nanotechnology. The study may lead to creating biological nanostructures with precise dimensions for various applications.
High levels of copper and iron in older adults can lead to cell damage and increase the risk of age-related diseases. To mitigate this, individuals over 50 should consider avoiding certain supplements and taking steps to lower their exposure to these metals.
A recent study identifies the GLRX5 gene as essential for generating iron-sulfur clusters and maintaining normal iron levels in human cells. The protein deficiency leads to sideroblastic anemia by impairing heme biosynthesis and depleting cytosolic iron in red blood cells.
A team of researchers from the University of Exeter has conducted a six-week archaeological expedition to rural Andhra Pradesh in India to study the origins of high carbon steel-making. They recorded over 120 sites where iron and steel were produced, including those associated with the production of wootz steel.
A new study published in the American Journal of Health Promotion shows that teenagers who consume 100% fruit juice have a more nutrient-dense diet compared to non-consumers. The study found lower intakes of total dietary fat and saturated fat, as well as higher intakes of key nutrients like Vitamins C and B6, folate, potassium, and iron.
A study of 269,717 new hemodialysis patients found that dialysis centers using larger doses of erythropoiesis-stimulating agents (ESAs) in patients with low hematocrit levels had lower mortality rates. Conversely, centers using more frequent iron dosing in higher hematocrit ranges showed increased mortality risk.
Thalassemia Foundation of Canada awards Concordia University professor Dr. Peter Pawelek a two-year grant to study a receptor protein found on the surface of a lethal bacterial pathogen that can 'hijack' thalassemia treatment drugs. The research aims to develop new antibiotics to combat opportunistic infections in thalassemia patients.
Researchers discovered a magnetometer system in the upper beak of birds, composed of over 500 dendrites that encode the magnetic field information. This system helps birds create a magnetic map for spatial orientation, contradicting previous myths about iron-based magnetoreception.
A new LSTM-led study aims to investigate the effects of long-term weekly iron and folic acid supplementation on anaemia and malaria risk in young women. The research seeks to strengthen adolescent health services and develop effective preventative programmes for anaemia control.
Researchers at Medical College of Georgia identified neogenin as a key player in regulating iron levels, providing a new target for drugs to treat iron deficiency and overload. Studies showed that neogenin inhibits the secretion of an RGM gene called hemojuvelin, which controls circulating iron levels.
A new study shows that transferrin, a blood protein, can alleviate anemia and prevent fatal iron overload in humans. The research, conducted at Albert Einstein College of Medicine, suggests that treatment with transferrin could benefit people with thalassemia and other types of anemia.
Researchers have discovered a way to visualize iron-sulfur clusters in living cells using a custom protein tag, enabling analysis of diseases involving these metalloclusters. This technique has high potential for helping find real treatments for diseases such as Friedreich's ataxia and myopathy.
Researchers at Washington University have discovered a channel protein that shields and transports the crucial heme molecule across cell membranes. The channel, found in plants and bacteria, helps protect heme from oxidative damage as it makes its journey outside the cell.
Researchers found Prussian blue can create essential biological molecules, including hydrogen cyanide and urea, under early Earth-like conditions. This study offers an alternative explanation for the formation of Banded Iron Formations.
Researchers discover supernova that fits predictions for a star hundreds of times the sun's mass, revealing new insights into star formation and heavy metal creation. The study also suggests hyper-giant stars may exist beyond 150 suns, challenging our understanding of celestial physics.
New data from a 10,000-kilometer cruise reveals that iron availability significantly controls the input of fixed nitrogen into the Atlantic Ocean. This finding is crucial for understanding global climate patterns and their potential implications on carbon dioxide sequestration.
Researchers found that iron-folic acid supplementation significantly reduced childhood mortality and low birth weight, but other supplement combinations did not provide the same benefit. The study suggests that antenatal iron-folic acid supplementation is a critical intervention for maternal and child health in developing countries.
Researchers found that iron naturally occurring in red wine causes the unpleasant fishy aftertaste when paired with fish. Low-iron red wines might be a suitable match for seafood, contrary to the traditional rule of thumb.
Researchers have identified a link between the mutated FGFR4 protein and the spread of childhood cancer. Additionally, changes in iron levels are found to affect inflammation via the TLR4 pathway, while glial cells play a crucial role in stimulating red blood cell production.
Scientists at the University of Leeds discovered that acidic clouds can convert large particles of iron from dust into small, soluble nanoparticles that plankton can use. This finding highlights a previously unknown source of bioavailable iron delivered to the Earth's surface in precipitation.
Researchers have developed a method to control the formation of carbon nanotubes, which can be used as semiconductors or metals. The breakthrough could lead to more powerful, compact and energy-efficient computers and ultra-thin electronic circuits.
Researchers from the National Oceanography Centre have made significant discoveries using iron isotopes to study sediment respiration and iron cycling processes in the deep-sea. The findings provide new insights into iron's role in the ocean's carbon cycle and its impact on climate.
Rice University chemist Bob Hauge's team creates bundles of SWNTs using a novel printing process, yielding a high yield of nanotubes. The process could lead to large-scale production of meter-long strands of nanotubes.
Two papers published in APS Physics journals describe different electron behavior in iron-based superconductors, suggesting distinct origins. The findings challenge theories on the similarities between these materials and cuprates, potentially altering the direction of research in this field.
In the high-latitude North Atlantic, low iron availability unexpectedly limits summer biological production. Experimental results show that adding iron increases photosynthetic efficiency and growth of phytoplankton, but insufficient iron is available to support the bloom.
A study by UC Davis geochemists has produced the first picture of how different isotopes of iron were initially distributed in the solid Earth 4.5 billion years ago. The discovery could lead to investigations into the evolution of Earth's mantle and its geologic history.
The collaboration aims to better understand the industry's needs and ensure expertise and capabilities are used effectively. BHP Billiton plans to relocate 15 researchers to the Queensland Centre for Advanced Technologies from July 2009.
A new study published in American Journal of Hematology finds that iron chelation therapy is not a reliable predictor of patient survival. Instead, degree of anemia and need for red blood cell transfusion at diagnosis are stronger predictors.
Researchers measured carbon particles from plankton blooms in the Southern Ocean, finding most don't reach the deep ocean. Plankton blooms stimulate carbon capture, but carbon tied up in plankton doesn't sink far or fast.
A new study found that iron deficiency in womb may delay auditory neural maturation in preemies, affecting sound processing and later language development. The research evaluated 80 infants over 18 months, revealing abnormal brain maturity in those with low iron levels.
Researchers found that the last atom in a line of single-atom contacts behaves differently than expected, altering the defining properties of ferromagnetic metals. The Kondo effect is observed in these tiny contacts, contradicting conventional wisdom about metal behavior at the nanoscale.
Researchers have constructed a systems biology map of iron metabolism, a crucial process in animal cell survival. The study aims to improve our understanding of iron regulation and its potential manipulation for therapeutic benefits.
Combining a mainstay antibiotic with drugs to deprive bacteria of iron boosts infection killing, according to Dartmouth researchers. Their study found that using two FDA-approved iron chelators and tobramycin eradicated biofilms by 90 percent.
Researchers at the University of Toronto have created a new green catalyst using iron that could replace expensive and toxic platinum metals in industrial chemical processes. This breakthrough has the potential to significantly reduce costs associated with drug production by avoiding costly purification techniques.
Researchers at Duke University Medical Center have identified a signaling pathway that initiates the flushing response associated with nicotinic acid. Analysis of human cell lines revealed that beta-arrestin proteins play a key role in this process, which may be targeted to prevent side effects while maintaining therapeutic benefits. I...
Researchers at the University of Utah developed a new method to locate trapped miners in collapsed mines by installing seismic listening devices on the ground. The system uses unique 'fingerprints' generated by miners banging on iron plates to pinpoint their location, showing promising results in tests.
Researchers found that high levels of iron cause oxidative stress and lead to the death of cancer cells. The study suggests a novel approach for treating cutaneous T cell lymphoma by selectively releasing iron.
Researchers at Diamond Light Source have developed a new technique using X-ray eyes to map metal distribution in brain tissue, which could lead to early diagnosis and treatment of Parkinson's disease. By studying the distribution of metal ions in affected regions, scientists hope to improve MRI detection and diagnosis.
Researchers discovered that iron spewed out of hydrothermal vents remains protected and usable by ocean organisms due to a complex matrix of carbon compounds. This finding challenges current paradigms about the iron cycle and opens up new research directions.
A team of scientists has made a groundbreaking discovery that challenges the long-held assumption about oceanic iron cycles. They found that organic compounds can capture some iron spewed by hydrothermal vents, enabling it to be carried away in seawater and reaching the surface, where it can nourish marine life more efficiently.
A University of Minnesota-led study connects iron sources from extreme depths to surface life, shedding light on nutrient cycling. Researchers found that hydrothermal vents release rusty iron, which can provide essential nutrients for sea life.
Scientists found that natural iron fertilization enhanced phytoplankton growth and productivity in the Southern Ocean, leading to two to three times more carbon export to the deep ocean. The research suggests that ocean islands are a key source of iron for these blooms.
A phase 3 clinical trial has shown that ferumoxytol, a novel intravenous form of iron, is effective in treating iron deficiency in CKD patients on dialysis. The study found significant improvements in hemoglobin levels compared to oral iron supplementation.
A study by Vanderbilt University researchers found a surprising link between brain iron levels and serotonin, a neurotransmitter involved in neuropsychiatric conditions. The team identified multiple trait differences affected by the SERT GK/ER variation, including traits associated with alcohol consumption and brain dopamine signaling.
Research found a high prevalence of gluten-sensitive enteropathy (GSE) in patients with iron deficiency anemia of unknown origin. A gluten-free diet improved anemia in GSE patients with mild duodenal lesions, suggesting GSE as a potential cause of iron-deficient anemia.
Only 3% of fast-food kids' meals met federal dietary guidelines, with fruit as a side dish and milk being common, while most exceeded sodium and added sugar limits. Researchers call on the industry to develop nutritious options and parents to make informed choices.
Ariel Anbar's research focuses on how changes in ocean element abundances influenced life, ecosystems, and evolution on Earth. He examines sedimentary rocks to infer past ocean compositions and investigates the role of essential nutrients like iron, sulfur, and copper.
Scientists at Carnegie Institution's Geophysical Laboratory found that highly oxidized iron in mantle minerals is crucial for heat transfer in the lower mantle. The discovery challenges current models of mantle dynamics and has significant implications for understanding material movement throughout the planet.
Using two million pounds of iron, researchers improved pollutant levels by 87%, removing BOD, nitrogen, phosphorus, and colors from industrial wastewater. The low-cost iron-based method has great potential for developing countries.
Scientists have created a new compound that selectively kills cancer cells while sparing healthy cells, offering hope for more effective chemotherapy drugs. The compound targets cancer cells' high iron levels, delivering toxic molecules that ultimately lead to cell death.
Researchers are studying the effects of lunar dust on the respiratory system and developing technologies to clean it from space suits. The powdery grey dirt is formed by micrometeorite impacts that can wreak havoc on equipment, but its unique properties also make it susceptible to magnets.
A glitch in iron transport may underlie Type IV mucolipidosis (ML4) and related symptoms like mental retardation and diminished motor abilities. The same deficit is also implicated in aging and neurodegenerative diseases such as Alzheimer's and Parkinson's, leading to potential new avenues for treatment.
A study published in PLoS One found that a restricted-calorie diet can reduce iron accumulation in muscle cell mitochondria, which can contribute to muscle loss in aging adults. The research suggests that reducing caloric intake early on may help limit muscle wasting in later years.
Adding intravenous iron to chemotherapy-induced anemia treatment boosts response rates by up to 50% and reduces treatment duration, according to a new study. Lower doses of darbepoetin alfa also show improved results with the addition of iron therapy.
Researchers at UCLA and Intrinsic LifeSciences have developed the first method to directly measure hepcidin, a hormone that regulates iron absorption. The new blood test will help clinicians diagnose conditions like anemia of chronic disease and hemochromatosis more efficiently.
Researchers have adapted a human test to screen for elevated iron levels in marmosets and tamarins, enabling early identification and treatment of hemosiderosis. This diagnostic tool also helps veterinarians provide tailored care to individual animals.
Researchers at the University of Utah have developed a rapid test for hepcidin, which helps diagnose anemia related to chronic illness and diseases of iron overload. The test can distinguish between causes of iron overload, enabling doctors to provide more accurate diagnoses.
Researchers found that certain bacteria can harness iron from the environment or human host using a unique gene. This discovery could lead to new ways to target diseases like tuberculosis by limiting access to essential iron sources.
Researchers at Dartmouth College have identified a crucial gene involved in chloroplast iron acquisition and efficient photosynthesis. The FRO7 gene is essential for plants to take up iron from the soil, particularly in iron-deficient conditions.