Articles tagged with Nanoparticles
Researchers at the University of Pennsylvania developed lipid nanoparticles that modify immune metabolism to strengthen mRNA vaccines and reduce common side effects. The new lipid boosts the metabolism of immune cells, providing energy for the body's defenses while dialing down inflammatory signals.
Researchers engineered nanoparticles that can educate the immune system to find and destroy disease-causing cells throughout the body. The nanoparticles were successful in depleting and destroying diseased immune cells in mice, with 95% of target B cells depleted in circulating blood within 24 hours.
Engineers at the University of Pennsylvania have developed LIBRIS, an automated microfluidic platform capable of generating lipid nanoparticle formulations at high speed and scale. This enables the creation of large, systematic datasets needed to train predictive AI models, accelerating the design of lipid nanoparticles for mRNA delivery.
Researchers introduce Fe₃O₄@mPEG-Ag nanoparticles as a non-antibiotic strategy to combat drug-resistant bacteria. The novel nanomaterial demonstrates strong antibacterial activity against clinically relevant multidrug-resistant strains.
Researchers at RCSI have developed an RNA-activated implant that delivers growth-promoting particles to injured nerve cells, encouraging them to regrow after spinal cord injury. The implant helps overcome molecular barriers by silencing a gene called PTEN.
A recent study suggests that combining melatonin with zinc oxide nanoparticles can improve hormone levels and reduce oxidative stress in male rats treated with cyclophosphamide, a chemotherapy drug known to damage rapidly dividing cells. The combination of these antioxidants improved sperm-producing cell preservation and reduced reprod...
In a mouse study, researchers successfully used RNA micelles to shrink metastasized tumors in lungs by delivering chemotherapy drugs and an RNA molecule that blocks cancer survival. The treatment significantly reduced tumor growth and improved outcomes for mice with colorectal cancer lung metastasis.
Researchers developed a novel nanoparticle system to cross the BBB, target infection sites, and release antibacterial agents locally. This strategy effectively disrupts biofilms, eliminates drug-resistant bacteria, and reduces neuroinflammation.
A team of researchers at Northern Arizona University discovered that fabricated gold, copper and iron nanocrystals exhibit pentagonal constructs resembling natural snowflakes, governed by emergence dynamics. This phenomenon holds key findings for controlling nanomaterial synthesis and advancing the field.
Boston College researchers used piezoelectric nanoparticles to trigger macrophages, a key part of the body's immune response. The study suggests that this method could be used to activate immune cells specifically at an infection or tumor site, avoiding side effects associated with systemic administration of drugs.
A new study reveals that Cornell prime dots, ultrasmall fluorescent particles, can reprogram the tumor microenvironment to make it more responsive to treatment. The nanoparticles induce anti-tumor effects by stimulating innate immune responses and reprogramming key immune cells.
Researchers found that Cornell prime dots can reprogram the tumor microenvironment, transforming melanoma and other aggressive solid tumors into responsive ones. The particles stimulate innate immune responses, halt cancer cell proliferation, reduce immune suppression, and repurpose key immune cells to attack cancer more effectively.
Scientists have identified two key forces that shape iron nanoparticles' stability in environments, including aggregation and phase transformation. Understanding these processes can improve strategies for managing water quality and contaminant transport.
A research team at CUNY and UT Austin discovered a way to control dark excitons, highly promising for quantum information and advanced photonic applications. They amplified light emission by 300,000 times, making them visible and controllable.
Researchers at the Institute of Advanced Materials aim to develop sustainable, high-performance lead-free memristors for neuromorphic computing. The MemSusPer project seeks to improve perovskite layer properties and test new materials for enhanced electrical conductivity.
A new study found that magnetoelectric nanoparticles can locate and destroy pancreatic tumors in preclinical models, reducing tumor size by one-third and extending survival time. The treatment uses no drugs or invasive procedures, instead guiding the nanoparticles to the tumor site using a small magnet and activating them with an MRI s...
MIT researchers have developed new nanoparticles that deliver the immune-stimulating molecule IL-12 directly to ovarian tumors, eliciting a strong response and clearing tumors in over 80% of mice. This treatment combines with checkpoint inhibitors to launch an attack on cancer cells without causing side effects.
A new method developed at the University of Warwick offers a simple way to calculate how irregularly shaped nanoparticles move through air. The study reworks a 100-year-old formula to bridge a key gap in aerosol science, providing accurate predictions for particles of any shape.
Scientists have characterized lipid nanoparticles' internal shape and structure, which correlates with how well they deliver therapeutic cargo. The research provides a blueprint for engineering more effective RNA therapies by matching LNP designs to specific therapies and tissues.
Researchers discovered that nano-biochar acts as an electron shuttle, transforming silver ions into metallic nanoparticles in rice roots. The process reduces the toxicity of silver ions while promoting their formation and accumulation inside plant cells.
A new technique allows engineers to more precisely place patches on microscopic building blocks, controlling their assembly into designer structures. This stenciling method provides a quantum leap in control over the building blocks' designs, enabling the creation of sophisticated materials from nanoparticles.
Scientists have found that environmental coatings on microscopic plastic particles can bypass some skin cells' defenses, allowing them to stay inside the body longer. This highlights the importance of studying the interaction between nanoplastics and human skin, as well as the potential health risks associated with these tiny particles.
Researchers have developed microscopic nanoparticles that can seek out and attach to damaged liver cells, helping to stop disease progression. The nanoparticles are engineered to recognize and selectively bind to a protein found only on Kupffer cells in the liver, promoting anti-inflammatory behavior and delivering medicine directly to...
The review highlights the importance of clean transfers in 2D material research, emphasizing that it can make or break an experiment. The authors propose a unified approach to transfer methods, synthesis, and testing to improve reproducibility and reliability.
A new human lung alveolus chip model enables investigation of viral replication, inflammatory responses, and genetic off-target effects of a novel pan-influenza CRISPR therapy. The study achieved significant reductions in virus load and host inflammatory response after a single administration.
Researchers have developed atomic-level precision patterning on nanoparticle surfaces using stencils, creating 'patchy nanoparticles' with various shapes and functions. The technique allows for large-scale production of batched particles with intricate designs, enabling the creation of novel materials and metamaterials.
Researchers at UMass Amherst have developed a nanoparticle-based vaccine that prevents melanoma, pancreatic and triple-negative breast cancer in mice. The vaccine achieved remarkable survival rates, with up to 88% of vaccinated mice remaining tumor-free.
Researchers have generated a new ring-shaped protein nanomaterial capable of strongly binding to and neutralizing the SARS-CoV2 virus. The system can integrate therapeutic and diagnostic capabilities and be adapted to combat other viruses.
Researchers developed a nanotechnology strategy that reverses Alzheimer's disease by targeting the blood-brain barrier and restoring its natural waste-clearing pathway. The therapy achieved a significant reduction in amyloid-β levels and improved cognitive function in mouse models, showing promise for treating dementia.
Hanbat National University researchers have developed a new method for enhancing the performance of solid oxide fuel cells by inducing cobalt exsolution in high-temperature oxidizing atmospheres. This process results in improved electrochemical properties and higher oxygen reduction reaction activity, making it a promising direction fo...
Researchers explain how iron nanoparticles form in water or on minerals, organic matter, and microbial biofilms, influencing ecosystem health and pollutant movement. Organic molecules and microbes also play major roles in nanoparticle growth and transformation.
Researchers at the University of Minnesota have developed a new method for producing iron that eliminates CO2 emissions and can be performed at room temperature. The process uses hydrogen gas plasma to strip oxygen from iron ore, producing pure iron and water vapor.
Scientists have developed a promising strategy for the selective hydrogenation of 5-hydroxymethylfurfural (HMF) using a porous carbon-supported Ni-ZnO nanoparticle catalyst. This breakthrough enables solvent-regulated selectivity and exceptional efficiency in producing valuable products such as BHMF and DMF.
Researchers from Universitas Gadjah Mada develop a breakthrough nanotechnology that converts plastic waste into glowing particles detecting toxic metals in drinking water with high precision and low cost. The innovation is a powerful step toward a circular economy, where waste becomes a resource for public health.
Scientists have successfully demonstrated quantum squeezing of a nanoscale particle, achieving motion uncertainty smaller than quantum mechanical fluctuations. This achievement paves the way for basic research and applications like autonomous driving without GPS.
Researchers at Pohang University of Science & Technology have successfully synthesized Prussian Blue with an octahedral morphology by using a specialized solvent. The new crystal shape enhances electrochemical reactivity and stable performance in sodium-ion hybrid capacitors.
Researchers found that soot particles can transform their shape and behavior within hours of becoming airborne, altering their ability to warm or cool the atmosphere. This rapid transformation affects both soot's warming and cooling effects, as well as its lifetime.
Researchers discovered a new way to enhance light emission in nanoparticles, leading to the visualization of infrared radiation. The technique, which involves simultaneous excitation with two near-infrared beams, could have applications in microscopy and photonic technologies.
Researchers developed a new model and theory to explain nanoparticle growth dynamics, accounting for six essential characteristics of nanoparticle growth. The new theory provides fresh physical insights into the role of nanoparticle motion and configurational degeneracy on their nucleation and growth.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
Researchers at Stanford Medicine developed a non-invasive system that delivers drugs to specific regions of the body, reducing unwanted side effects. The system uses nanoparticles encapsulated in a sugar solution that responds to ultrasound stimulation, allowing for precise delivery of medication.
The book sheds light on nanomaterials, metamaterials, and smart materials' synthesis, classification, and characterization techniques. It discusses size-dependent behavior, fabrication challenges, and interdisciplinary applications with practical implications for healthcare, energy, and electronics.
Researchers developed a neoAg mRNA-based vaccine that induces higher frequency of neoAg-specific cytotoxic T cells in mice, leading to tumor regression and eradication. The combination with anti-PD-1 therapy enhances antitumor efficacy, especially against peritoneal metastasis.
Researchers at CUNY ASRC Nanoscience reveal that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental stress. The findings offer a promising new approach to stabilizing biomolecules like vaccines and therapeutic proteins without refrigeration.
Researchers at Stanford University have developed a novel nanodevice that manipulates light using sound waves, enabling precise control over color and intensity. This breakthrough has significant implications for various fields, including computer displays, virtual reality, and optical communications.
A new biosensor has been developed to detect urea levels using visible color changes, offering a clear and multicolor visual cue across a wide concentration range. The sensor can detect urea down to 0.098 µM in solution and 0.2 µM in solid form, significantly outperforming traditional methods.
A recent study detected titanium dioxide particles in 100% of animal milk samples and 83% of infant formulas, revealing widespread contamination. The findings suggest that infants' exposure to these particles does not end at birth, raising concerns over human and animal health.
Researchers at the University of Ottawa have made a breakthrough in developing nanoparticles that not only deliver drugs but also contribute to treatment. Their proof-of-concept study shows that particles can be armed with therapeutic potential, revolutionizing the field of nanomedicine.
Laser-generated nanoparticles offer a cleaner, scalable alternative to traditional chemical synthesis methods for electronics applications. The method, called laser ablation in liquids, produces surfactant-free, highly pure metal-based nanoparticles with tailored surface properties.
Researchers at the University of Pennsylvania designed a new recipe for mRNA vaccines by adding phenol groups, which reduce inflammation and improve vaccine effectiveness. The modified lipids improved vaccine performance in various diseases, including COVID-19, cancer, and genetic diseases, with enhanced efficacy and reduced side effects.
Researchers detected nanoplastic particles smaller than 1 µm in all depths analysed across the 12 measurement sites, with PET, PS, and PVC being the most common types. The study estimates around 27 million tonnes of nanoplastic are stored in the uppermost water layer of the North Atlantic.
Researchers found that sewage spills from land to sea coincided with winds of at least 6.5m/s on 178 days within a two-year period, potentially sending microplastics into the air. The study suggests that coastal towns and cities may be exposed to billions of airborne microplastic particles.
Researchers at Case Western Reserve University have received an NSF CAREER Award to develop synthetic DNA nanoparticles with potential applications in gene therapy. The program aims to study how these particles behave inside cells and potentially design therapeutics for genetic diseases.
Scientists developed a method to use ultrasound to chemically activate drugs, selectively targeting tumors and stimulating immune cells. This approach achieved a 99% tumor suppression rate in colon cancer models without harming healthy tissues.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
Scientists at Xi'an Jiaotong-Liverpool University developed a new nanoparticle capable of carrying high doses of chemotherapy drugs while staying stable for extended periods. This innovation could make treatments more effective and reduce side effects.
Researchers have developed a technique to observe phonon dynamics in nanoparticle self-assemblies, enabling the creation of reconfigurable metamaterials with desired mechanical properties. This advance has wide-ranging applications in fields such as robotics, mechanical engineering, and information technology.
A new study reveals how nanoparticles can interfere with photosynthesis in plants, reducing their ability to convert sunlight into food. The research team found that nanoparticles undergo changes in pH and pick up lipid coatings from plant membranes, boosting their binding to RuBisCO and impairing its function.
Researchers developed self-propelled ferroptosis nanoinducers to enhance cancer therapy by inducing programmed cell death. The nanotherapeutics exhibited enhanced diffusion and deep tumor penetration while maintaining biocompatibility.
Researchers at NYU Abu Dhabi have developed a breakthrough paper-based diagnostic device that can detect COVID-19 and other infectious diseases in under 10 minutes. The Radially Compartmentalized Paper Chip (RCP-Chip) is a fast, affordable, and portable solution for on-site screening of infectious diseases.