Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers developed a novel anode material combining hard carbon with tin, enhancing energy storage and stability. The composite structure shows excellent performance in lithium-ion and sodium-ion batteries, promising applications in electric vehicles and grid-scale energy storage.
The companies have created a microfluidic device-based LNP production system that enables precise control over particle size, addressing previous productivity issues. The system can produce various types of LNPs in small-batch or mass quantities, from personalized medicine to vaccines for infectious diseases.
Researchers developed a dual-action nanotherapy that converts white fat into beige fat and reduces obesity-related inflammation, significantly improving metabolic health without detectable toxicity.
Researchers found that nanoplastics in soil exhibit varying behavior depending on soil type and pH levels, affecting their aggregation and adsorption onto soil particles. Understanding these interactions is crucial for developing effective strategies to mitigate plastic pollution.
A new study by Columbia University researchers reveals that 75-80% of plastics, known as semicrystalline polymers, break down into hazardous micro- and nanoscopic fragments. These fragments can persist in the environment for centuries and cause significant damage to living things.
Researchers have found that oxalic acid can generate nanoparticles of the toxic metal gadolinium in human tissues, which has been associated with serious health problems such as nephrogenic systemic fibrosis. This discovery may lead to a possible way to mitigate some of the risks associated with MRI scans.
Researchers at MIT have developed a method to mass manufacture nanoparticles that target cancer cells, eliminating the need for manual polymer mixing and streamlining production. This approach integrates good manufacturing practice (GMP)-compliant processes, making it suitable for large-scale production of cancer treatments.
Researchers developed bacteria-enhanced graphene oxide nanoparticles that effectively destroy tumors through a three-pronged mechanism. The nanocomposites combine chemotherapy, immune activation, and photothermal heating to suppress tumor growth and activate strong immune responses in mice.
A new class of zwitterionic phospholipids, DOPE-Cx, enhances the functional delivery of mRNA via lipid nanoparticles, overcoming endosomal escape and improving mRNA expression. This breakthrough paves the way for advanced therapeutic applications, including mRNA vaccines, cancer treatment, and protein replacement therapy.
Researchers at University of Nottingham use transmission electron microscopy to observe real-time growth and contraction of Palladium nanoparticles. The study reveals a unique cyclic process where nanoparticles grow, dissolve, and re-grow, potentially leading to the development of new efficient catalysts.
Researchers developed a strategy to regulate hydrogen bond networks at electrolyte-electrode interfaces, accelerating proton transfer in CO2 reduction reactions. The approach involves introducing extra catalytic centers, such as cubic phase molybdenum carbide, to enhance water dissociation and facilitate proton generation.
Conjugated small molecular nanoparticles (CSMNs) have shown promise in near-infrared phototheranostics (NIR PTs) for imaging, therapy, and synergistic treatment. Strategies to improve performances and extend absorption wavelengths are crucial for their clinical translations.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
Researchers at Oregon State University have developed uniquely shaped, fast-heating nanoparticles that can effectively treat ovarian tumors. The nanoparticles exhibit exceptional heating efficiency when exposed to an alternating magnetic field, raising temperatures by 3.73 degrees Celsius per second.
A new bacterial protein, BeeR, has been identified and its structure is being used to develop protein nanoparticles for targeted cancer drug delivery. The protein forms a hollow tube with a cavity capable of containing drug molecules.
A new study found that adding green-synthesised iron nanoparticles (G-nFe) to pig manure neutralises bioavailable copper, reducing environmental risks. The process reduces exchangeable cooper by 66.8%, carbonate-bound copper by 47.5%.
Researchers at the University of Birmingham have developed a new method for rapid scalable preparation of uniform nanostructures directly from block polymers, significantly reducing processing time from weeks to just minutes.
A study by Pusan National University uncovers the impact of nanoplastic exposure on red blood cell maturation in zebrafish embryos. Exposure to polystyrene nanoparticles disrupts normal blood cell development, leading to an increase in immature RBCs and a decrease in mature RBCs.
Researchers have developed an innovative acoustofluidics-based approach for delivering biomolecular cargos into cells, overcoming limitations of traditional methods. The new method enables controlled contact between cells and nanoparticles, enhancing membrane permeability and improving delivery efficiency.
Magnetic nanoparticles are guided to tumors using a magnet and heated by a laser to destroy cancer cells. Researchers developed nanoparticles that outperform conventional photothermal agents, killing cancer cells with high efficiency.
Researchers developed a nanoparticle that delivers an mRNA vaccine targeting a KRAS antigen, boosting the immune response against pancreatic cancer. Experiments in mice showed inhibited and prevented tumor growth, as well as long-term protection against recurrence.
Core-shell nanoparticles offer effective drug encapsulation, shielding from degradation, and controlled release. This innovation enables targeted drug delivery, improving treatment outcomes and reducing side effects. The versatility of these nanoparticles allows for tailored materials to suit different therapeutic needs.
The study resolves a long-standing challenge in observing nanostructures and enables real-time tracking of three-dimensional atomic structural changes in individual nanoparticles. Researchers successfully captured the precise moments when surface atoms detached, rearranged, or reattached in three dimensions.
Researchers have developed an AI method to illuminate nanoparticle behavior, revealing key dynamics and instabilities. The technique combines electron microscopy with AI to capture atomic-level structural changes at unprecedented time resolution.
Researchers used molecular modeling techniques to understand nanoplastic interactions with natural organic matter in aquatic ecosystems. The study found that aged nanoparticles form stable aggregates through a combination of intermolecular forces, including hydrogen bonding and cation bridging.
Researchers have discovered a way to trap iodine in perovskite solar cells using alumina nanoparticles, enhancing lifespan and stability. The modified solar cells maintained high performance for over two months under extreme conditions.
Researchers developed new photon avalanching nanoparticles that exhibit high nonlinearities, overcoming challenges in realizing intrinsic optical bistability at the nanoscale. The breakthrough paves the way for fabricating optical memory and transistors on a nanometer scale comparable to current microelectronics.
Scientists at Nagoya University developed a nanoscale video game that manipulates nanoparticles in real-time, enabling interaction between virtual and physical objects. The 'nano-mixed reality' system has potential applications in nanotechnology and biomedical engineering, including 3D printing and targeted virus killing.
Deep Nanometry enables high-speed analysis of nanoparticles, detecting even trace amounts of rare particles like extracellular vesicles indicative of colon cancer. This technique has potential applications in various fields including vaccine development and environmental monitoring.
Researchers have developed a novel LiMn₂O₄ electrode material with improved lithium extraction capacity and cycle stability. The SnO₂ nanoparticle island-modified LMO electrode material shows good selectivity and stability for lithium ions, enabling efficient electrochemical salt lake lithium extraction.
University of Queensland researchers have successfully introduced genetic material into plants via their roots using nanoparticle technology, enabling rapid crop improvement. This innovative approach could lead to the development of new crop varieties with improved yield and quality without traditional breeding methods.
A new study published in Nature Materials demonstrates a lipid nanoparticle system capable of delivering messenger RNA to the brain via intravenous injection. The technology could pave the way for future treatments for conditions like Alzheimer's disease and drug addiction.
Researchers unveil Ba-Si orthosilicate oxynitride-hydride as a transition metal-free catalyst, offering a more sustainable approach to ammonia production. The novel catalyst demonstrates exceptional stability and higher activity than conventional ruthenium-loaded MgO catalysts.
Researchers detect nanoplastic particles on glaciers in France, Italy, and Switzerland, suggesting sea pollution as the source. The concentrations of nanoplastics varied between locations, with wind direction affecting their accumulation.
Researchers at the University of Konstanz developed an AI system to speed up nanoparticle measurements, reducing time from hours to minutes. The system, based on Meta's open source AI technology, can accurately count complex particles and measure individual particles with high precision.
The Terasaki Institute for Biomedical Innovation has announced the recipients of its inaugural Keith Terasaki Mid-Career Innovation Award. Dr. Liangfang Zhang and Dr. Aydogan Ozcan were recognized for their innovative approaches to translating groundbreaking research into real-world impact.
A new liposarcoma treatment using CAR T cells has shown promising results in clinical trials, with a response rate of 20-40% in patients with advanced or metastatic disease. Additionally, researchers have developed more efficient drug-delivery nanoparticles that can improve cancer treatment outcomes.
A new biodegradable polymer-based delivery system efficiently transports mRNA, outperforming existing lipid nanoparticles in delivery efficiency and expression duration. The study also shows improved immune response results without liver accumulation or toxicity.
Researchers developed surface-modified apatite coatings using pH control to enhance cell adhesion and improve the biocompatibility of implants. The study found that controlling the nanoscale surface layer of apatite nanoparticles leads to better binding affinity with biological tissues.
Researchers have developed a technique for inkjet printing arrays of special nanoparticles that enables the mass production of long-lasting wearable sweat sensors. These sensors can monitor various biomarkers in real-time, providing patients and physicians with continuous insights into their health.
A new nanotechnology-based drug delivery system has been developed to save patients from repeated surgeries. The approach, called Pericelle, uses a paste of nanoparticles containing hydrogel on transplanted veins to prevent blockages, which can lead to repeated surgeries in heart and dialysis patients.
Researchers at UC Davis created nanoislands with trapped platinum clusters, demonstrating improved hydrogenation catalytic activity and stability. The confinement of metal clusters on a tiny island of cerium oxide supports the production of stable catalysts for the chemical industry.
Scientists at Tel Aviv University successfully transport mRNA-based drugs to the immune system of small and large intestines without passing through the liver. The breakthrough could enable treatments for inflammatory diseases such as Crohn's and colitis.
Researchers develop BEND lipids to improve LNP mRNA delivery and gene editing by breaking through the endosomal membrane. The new lipids outperform existing LNPs used in COVID-19 vaccines, with improved efficacy rates up to tenfold.
The team's novel technique enables high-throughput screening of nanoparticle shapes, sizes, and modifications, reducing associated screening costs. The research demonstrates the distinct preferences of tumour cells for certain nanoparticle configurations, enabling personalized cancer treatments that are safer and more effective.
Researchers introduce a trimetallic catalyst supported on defective ceria, achieving extraordinary efficiency in CO2 reduction. The unique metal-support interaction fine-tunes the electronic structure, enabling optimal performance and setting new benchmarks in catalysis.
Researchers have developed a groundbreaking approach using specially designed peptides to improve drug formulations, significantly enhancing anti-tumor efficacy in leukemia models. The innovative method achieves high drug loadings and optimizes delivery to targeted areas, holding significant potential for treating various diseases.
Researchers developed a nanoparticle-based vaccine that generates antibodies targeting conserved regions of sarbecovirus receptor-binding proteins, offering broader protection against multiple strains. The vaccine demonstrated strong antibody responses and protection in animal studies against diverse SARS-CoV-2 and other sarbecoviruses.
The project aims to create novel platforms and formulations capable of delivering large, complex biologics with minimal toxicity and immune system responses. The developed technologies could be applied not only in combat areas but also in the general public to protect against infectious diseases and other health threats.
Researchers developed an automated analytical method to analyze single atom catalysts, which could lead to more efficient fuel production and sustainable energy. The new tool, called MS-QuantEXAFS, automates the analysis process, reducing time from days to months.
Researchers developed a novel approach using lipid nanoparticles to deliver mRNA and siRNA, restoring tumor suppressors and inhibiting tumor drivers in prostate cancer cells. This technique holds promise for treating various types of cancer by targeting specific pathways related to tumor growth and suppression.
Researchers developed a novel inhalable therapeutic delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by marine mussels. The approach leverages the adhesive properties of mussel proteins to enable selective payload release and minimize adverse effects.
Scientists have successfully created silver nanoparticles using store-bought goji berries, a process that eliminates the need for additional chemicals and is biologically compatible with humans. The nanoparticles were tested for their antimicrobial activity against Staphylococcus aureus and confirmed to be effective.
Researchers create nanosensors that can measure piconewton and micronewton forces remotely using light, enabling multiscale sensing capabilities. These sensors operate in previously inaccessible environments with benign infrared light, revolutionizing technologies from robotics to medicine and space travel.
Researchers are discovering selenium nanoparticles' potential in cancer prevention, inflammation reduction, and tumor treatment through their ability to activate the immune system and reduce inflammation. SeNPs are also being explored as vaccine adjuvants to improve immune cell activation and boost cancer vaccine efficacy.
Researchers developed biodegradable polymeric nanoparticles that selectively target cancer cells with two approved drug pairs for skin and breast cancers. The treatment showed significantly enhanced therapeutic effects, reduced tumor size, and prolonged median survival in mice.
Researchers have developed peptide-guided nanoparticles that can target specific cells in the brain, including neurons, marking a significant step toward potential mRNA treatments for neurological diseases. The innovation uses peptides to precisely deliver mRNA to endothelial cells lining blood vessels and neurons.
A team of University of Melbourne researchers has developed a novel drug delivery system composed of metal-biomolecule networks (MBNs), which eliminate the need for toxic drug carriers. The MBNs show antiviral, antibacterial, antifungal, anti-inflammatory and anti-cancer properties, potentially increasing success in drug development.
Chungnam National University researchers developed a magnetoplasmonic strain sensor that changes color in response to mechanical stress, offering a reliable and user-friendly solution for real-time health and activity tracking. The device is powered-free, versatile, and ideal for use in remote or extreme environments.
A new study shows targeted delivery of energy-disrupting gene therapy using nanoparticles shrinks glioblastoma brain tumors and aggressive breast cancer tumors in mice. The technology, mLumiOpto, induces light-activated electrical currents inside cells to disrupt mitochondria, leading to programmed cell death and DNA damage.