Articles tagged with Nanoparticles
A new liposarcoma treatment using CAR T cells has shown promising results in clinical trials, with a response rate of 20-40% in patients with advanced or metastatic disease. Additionally, researchers have developed more efficient drug-delivery nanoparticles that can improve cancer treatment outcomes.
A new biodegradable polymer-based delivery system efficiently transports mRNA, outperforming existing lipid nanoparticles in delivery efficiency and expression duration. The study also shows improved immune response results without liver accumulation or toxicity.
Researchers developed surface-modified apatite coatings using pH control to enhance cell adhesion and improve the biocompatibility of implants. The study found that controlling the nanoscale surface layer of apatite nanoparticles leads to better binding affinity with biological tissues.
Researchers have developed a technique for inkjet printing arrays of special nanoparticles that enables the mass production of long-lasting wearable sweat sensors. These sensors can monitor various biomarkers in real-time, providing patients and physicians with continuous insights into their health.
A new nanotechnology-based drug delivery system has been developed to save patients from repeated surgeries. The approach, called Pericelle, uses a paste of nanoparticles containing hydrogel on transplanted veins to prevent blockages, which can lead to repeated surgeries in heart and dialysis patients.
Scientists at Tel Aviv University successfully transport mRNA-based drugs to the immune system of small and large intestines without passing through the liver. The breakthrough could enable treatments for inflammatory diseases such as Crohn's and colitis.
Researchers at UC Davis created nanoislands with trapped platinum clusters, demonstrating improved hydrogenation catalytic activity and stability. The confinement of metal clusters on a tiny island of cerium oxide supports the production of stable catalysts for the chemical industry.
Researchers develop BEND lipids to improve LNP mRNA delivery and gene editing by breaking through the endosomal membrane. The new lipids outperform existing LNPs used in COVID-19 vaccines, with improved efficacy rates up to tenfold.
Researchers introduce a trimetallic catalyst supported on defective ceria, achieving extraordinary efficiency in CO2 reduction. The unique metal-support interaction fine-tunes the electronic structure, enabling optimal performance and setting new benchmarks in catalysis.
The team's novel technique enables high-throughput screening of nanoparticle shapes, sizes, and modifications, reducing associated screening costs. The research demonstrates the distinct preferences of tumour cells for certain nanoparticle configurations, enabling personalized cancer treatments that are safer and more effective.
Researchers have developed a groundbreaking approach using specially designed peptides to improve drug formulations, significantly enhancing anti-tumor efficacy in leukemia models. The innovative method achieves high drug loadings and optimizes delivery to targeted areas, holding significant potential for treating various diseases.
Researchers developed a nanoparticle-based vaccine that generates antibodies targeting conserved regions of sarbecovirus receptor-binding proteins, offering broader protection against multiple strains. The vaccine demonstrated strong antibody responses and protection in animal studies against diverse SARS-CoV-2 and other sarbecoviruses.
The project aims to create novel platforms and formulations capable of delivering large, complex biologics with minimal toxicity and immune system responses. The developed technologies could be applied not only in combat areas but also in the general public to protect against infectious diseases and other health threats.
Researchers developed an automated analytical method to analyze single atom catalysts, which could lead to more efficient fuel production and sustainable energy. The new tool, called MS-QuantEXAFS, automates the analysis process, reducing time from days to months.
Researchers developed a novel approach using lipid nanoparticles to deliver mRNA and siRNA, restoring tumor suppressors and inhibiting tumor drivers in prostate cancer cells. This technique holds promise for treating various types of cancer by targeting specific pathways related to tumor growth and suppression.
Researchers developed a novel inhalable therapeutic delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by marine mussels. The approach leverages the adhesive properties of mussel proteins to enable selective payload release and minimize adverse effects.
Scientists have successfully created silver nanoparticles using store-bought goji berries, a process that eliminates the need for additional chemicals and is biologically compatible with humans. The nanoparticles were tested for their antimicrobial activity against Staphylococcus aureus and confirmed to be effective.
Researchers create nanosensors that can measure piconewton and micronewton forces remotely using light, enabling multiscale sensing capabilities. These sensors operate in previously inaccessible environments with benign infrared light, revolutionizing technologies from robotics to medicine and space travel.
Researchers are discovering selenium nanoparticles' potential in cancer prevention, inflammation reduction, and tumor treatment through their ability to activate the immune system and reduce inflammation. SeNPs are also being explored as vaccine adjuvants to improve immune cell activation and boost cancer vaccine efficacy.
Researchers developed biodegradable polymeric nanoparticles that selectively target cancer cells with two approved drug pairs for skin and breast cancers. The treatment showed significantly enhanced therapeutic effects, reduced tumor size, and prolonged median survival in mice.
A team of University of Melbourne researchers has developed a novel drug delivery system composed of metal-biomolecule networks (MBNs), which eliminate the need for toxic drug carriers. The MBNs show antiviral, antibacterial, antifungal, anti-inflammatory and anti-cancer properties, potentially increasing success in drug development.
Researchers have developed peptide-guided nanoparticles that can target specific cells in the brain, including neurons, marking a significant step toward potential mRNA treatments for neurological diseases. The innovation uses peptides to precisely deliver mRNA to endothelial cells lining blood vessels and neurons.
Chungnam National University researchers developed a magnetoplasmonic strain sensor that changes color in response to mechanical stress, offering a reliable and user-friendly solution for real-time health and activity tracking. The device is powered-free, versatile, and ideal for use in remote or extreme environments.
A new study shows targeted delivery of energy-disrupting gene therapy using nanoparticles shrinks glioblastoma brain tumors and aggressive breast cancer tumors in mice. The technology, mLumiOpto, induces light-activated electrical currents inside cells to disrupt mitochondria, leading to programmed cell death and DNA damage.
Researchers have developed an mRNA cure for pre-eclampsia using a lipid nanoparticle, reducing maternal blood pressure and improving fetal health. The therapy, tested in pregnant mice, has shown promising results and is poised to move forward to human trials.
Researchers at Kaunas University of Technology (KTU) have developed a unique nanolaser that uses silver nanocubes to generate and amplify light. The laser's operating principle resembles a hall of mirrors, allowing efficient light generation in an optically active medium.
Researchers at the University of Ottawa have developed a nanoparticle strategy to deliver both mRNA and siRNA, enhancing and interfering with multiple gene and protein expressions. This approach holds significant promise for treating major diseases like cancer and cardiovascular diseases.
Researchers developed an immunotherapeutic platform using lipid-based nanoparticles to deliver therapeutic mRNAs, showing improved efficacy and reduced toxicity. The therapy stimulates the immune system to recognize and eliminate cancer cells, while preserving beneficial immune responses.
Professor Lutz Nuhn aims to create lipid-free capsules for RNA vaccines that don't require cooling and can initiate precise immune responses. He plans to equip the capsules with messenger substances to target cancer as well.
Researchers from Bar-Ilan University have uncovered a previously unknown phenomenon that enables precise control over molecular patterns on liquid droplet surfaces. The discovery, which involves a transformation between two types of structural defects, has broad implications for technologies such as vaccine design and nanoengineering.
Researchers found that COFs' catalytic activity comes from oxidic nanoparticles formed when cobalt ions detach, not the framework itself. The nanoparticles provide a suitable reaction environment and hold the catalysts in place, enabling efficient catalysis even under harsh conditions.
Scientists have created a method to recover and reuse quantum dots used in microscopic lasers, enabling the sustainable management of these valuable materials. The new recycling technique has been successfully tested on defective samples, resulting in the recovery of 85% of the quantum dots with minimal loss.
Researchers at Kyushu University develop a novel technique for building complex 3D microfluidic networks using plant roots and fungal hyphae in silica nanoparticles. This bio-inspired method enables the creation of intricate biological structures, opening new opportunities for research in plant and fungal biology.
Researchers have made significant strides toward creating inhalable mRNA medicines using a novel lipid-polymer nanoparticle. The nanoparticles successfully deliver aerosols to mice's lungs and demonstrate uniform protein expression in tissues.
Researchers at the University of São Paulo developed a novel nanotechnology-based solution to remove micro- and nanoplastics from water. The process uses magnetic nanoparticles that bind to tiny plastic particles and can be removed with a magnet.
Rice researchers have created a catalyst that leverages plasmonic photocatalysis to break down methane and water vapor into hydrogen and carbon monoxide without external heating. The new catalyst system enables on-demand, emissions-free hydrogen production, which could transform the energy industry.
Scientists have discovered that adding carbon to metal nanoparticles makes them 200 times more active, which could lead to significant cost savings and improved efficiency in industrial processes. The discovery was made possible by precise measurements and simulations of the interaction between metal nanoparticles and a carbon substrate.
Researchers at Aalto University have developed a method to create tiny vortices in light, which can carry information and potentially increase data transmission capacity by 8-16 times. The discovery uses quasicrystal design and manipulated metallic nanoparticles to achieve this feat.
A research team found that rainfall in the Amazon rainforest creates temporary bursts of nanoparticles that can grow into cloud condensation nuclei, essential for water vapor to condense and form clouds. This new understanding challenges previous theories on aerosol particles and their role in precipitation formation.
Researchers from the IBB-UAB have developed novel nanoparticles capable of trapping and neutralizing large quantities of SARS-CoV2 virus particles. These nanostructures could be used to manufacture antiviral materials such as wastewater and air filters, and develop new tests for early Covid-19 detection.
Researchers from Kyushu University successfully promoted singlet fission by introducing chirality into chromophores, achieving high SF efficiency in aqueous nanoparticles. This breakthrough enables applications in energy science, quantum materials, and photocatalysis.
Researchers at Terasaki Institute have developed simvastatin-loaded nanoparticles to target adipose tissue inflammation, promoting fat tissue browning and weight loss. The treatment effectively inhibits obesity-related inflammation, controlled white fat production, and demonstrated strong anti-inflammatory effects.
A new study in mice shows a unique mRNA delivery method can successfully edit faulty genes in fetal brain cells. The technology has the potential to stop progression of genetic-based neurodevelopmental conditions like Angelman syndrome and Rett syndrome before birth.
The study introduces a novel dynamic gas sensing platform using blue μLED-activated SnO2 nanoparticles, exhibiting excellent sensitivity, tunable selectivity, and rapid detection. The system can distinguish various gases under light illumination, contributing to healthier living environments.
Researchers develop laser solid-phase synthesis technique to produce graphene-shell encapsulated CrMnFeCoNi nanoparticles, exhibiting excellent electrocatalytic activity towards oxygen evolution reaction. The method offers simplicity, generality, and tunability to synthesize phase-separation-free HEA nanoparticles.
A groundbreaking study has demonstrated the clinical success of a new nanoparticle-based, laser-guided therapy for prostate cancer treatment. The therapy successfully eliminated cancerous cells in 73% of patients after 12 months while preserving key functions and side effects.
A novel nanoparticle therapy targets fat absorption in the small intestine, showing significant potential to prevent diet-induced obesity. The treatment involves inhibiting an enzyme called Sterol O-acyltransferase 2 (SOAT2), which plays a critical role in fat absorption.
Researchers developed a microchip that captures exosomes from blood plasma to identify signs of lung cancer, achieving 10x faster detection and 14x greater sensitivity. The chip uses twisted gold nanoparticles to distinguish between healthy patients and those with lung cancer.
Researchers at Osaka Metropolitan University have developed a promising solid electrolyte for all-solid-state batteries, showing high conductivity and formability. The new electrolyte, Na2.25TaCl4.75O1.25, also exhibits superior mechanical properties and electrochemical stability.
Researchers have identified a 'forcefield-like' defense system in solid tumors, which uses small extracellular vesicles to block nanoparticle-based therapies. The study found that tumor cells release sEVs carrying proteins that block the activity of cytotoxic T cells and intercept nanoparticles like a decoy.
Researchers at the University of Pennsylvania School of Engineering and Applied Science have discovered a novel means of directing lipid nanoparticles to target specific tissues. By incorporating siloxane composites into ionizable lipids, they were able to achieve tissue-specific delivery, particularly to the liver, lungs, and spleen.
A new method combines confocal fluorescence microscopy with microfluidic laminar flow to detect nanoparticles and viruses quickly and accurately. The approach uses a 3D-printed Brick-MIC setup for sensitivity and specificity improvements, potentially changing virus detection in clinical settings.
Researchers at Lund University found that grazing zooplankton and phytoplankton diatoms are severely impacted by nanoplastic particles, while cyanobacteria remain unaffected. The study's findings have significant implications for food chains and ecosystem processes.
Researchers at Texas A&M University have developed a method to recharge cellular mitochondria using nanotechnology, potentially extending healthy lifespans and improving outcomes for patients with age-related diseases. The molybdenum disulfide nanoparticles stimulate mitochondrial regeneration, helping cells generate more energy.
Researchers from Osaka Metropolitan University have developed a method to detect coronavirus spike proteins quickly and selectively using a light-induced immunoassay. The technique uses a milliwatt-level laser and can complete the entire process in under 5 minutes.
The Indian Institute of Science team proposes an on-site alternative using iron nanoparticles that can remediate heavy metals. The S-CMC-nZVI material showed nearly 99% efficiency at Cr6+ removal under different conditions.
The Rice-led MURI project aims to develop innovative single-atom reactor systems and analyze various chemical processes of strategic importance to the DOD. The researchers, led by Naomi Halas, seek to improve energy efficiency and reduce protocol intensity in chemical reactions.
Researchers developed a breakthrough nanoparticle technology that offers an effective solution to diagnose and treat atherosclerosis in a non-invasive manner. The innovative theranostic approach can target atherosclerotic plaques and deliver therapeutic agents directly to inhibit the progression of atherosclerosis.
Researchers at ETH Zurich have developed a new method to degrade perfluorooctane sulfonates (PFOS), a subgroup of forever chemicals. Using piezocatalysis, the team was able to break down 90.5% of PFOS molecules in water samples, offering a potential solution to environmental pollution.
A new study proposes a method to accurately heal dynamic cracks in membranes using nanoparticles, improving separation performances and durability. The technique has been shown to save up to 85% of energy consumption while extending the lifespan of the membrane.