Articles tagged with Nanoparticles
Researchers at Oregon State University have developed a novel device that can improve the delivery of gene therapy for patients with inherited lung diseases such as cystic fibrosis. The device uses aerosolization technology to carry messenger RNA to patients' lungs, reducing shear stress and improving precision.
Researchers developed a new 'proactive vaccinology' approach to build vaccines before disease-causing pathogens emerge. The Quartet Nanocage vaccine trains the immune system to target specific regions of eight coronaviruses, providing broad protection against known and unknown strains.
Researchers at Sylvester Comprehensive Cancer Center have developed a nanoparticle that can penetrate the blood-brain barrier, potentially targeting both primary breast cancer tumors and brain metastases in one treatment. The method shows early promise in preclinical models, where it shrinks breast and brain tumors.
Researchers analyzed asteroid Ryugu samples to study magnetic and physical bombardment environment in interplanetary space. The investigation revealed changes likely caused by micrometeoroid bombardment, providing insights into the solar system's early stages.
Researchers have discovered that rice bran-derived nanoparticles exhibit strong anticancer effects, selectively targeting cancer cells while sparing healthy tissue. The nanoparticles reduced tumor growth and inhibited metastatic cell growth in mice models.
Researchers from the Institute for Basic Science created QLEDs using a ternary nanocomposite film that enhances carrier delivery to quantum dots, resulting in optimal device performance. The devices exhibit high brightness and low threshold voltage, with no damage when stretched up to 1.5 times.
A new 'rechargeable nanotorch' allows researchers to track the movement of cell-based microrobots in real-time, using afterglow luminescence imaging. The nanotorches can be recharged non-invasively with near-infrared light, enabling long-term tracking and potential applications in cancer treatment.
Researchers have developed protein-based nanoparticles that target and destroy specific cancer cells, providing a more efficient treatment option. This technology uses natural secretory granules found in the endocrine system to deliver proteins over an extended period.
Purdue University researchers create biocompatible nanoparticles modified with ATP that slowly release anti-cancer drugs and recruit immune cells to fight tumors. In mouse studies, these nanoparticles improved the effectiveness of paclitaxel against various types of cancers, including those in distant locations.
Researchers developed a self-cleaning wall paint using waste-valorized titanium oxide nanoparticles, which can bind and break down pollutants, and then degrade them when exposed to sunlight. The paint combines several advantages, including air pollutant removal, longer durability, and reduced production costs.
Researchers at Stanford University have successfully 3D printed tens of thousands of Archimedean truncated tetrahedrons, a geometry predicted to produce promising new materials that can change form in an instant. These nanoparticles can shift between states rapidly by rearranging particles into new geometric patterns.
A new study by Duke University researchers provides fundamental insights into autoimmune diseases, including systemic lupus erythematosus. They developed a system to test how DNA attached to nanoparticles interact with the immune system, revealing that larger nanoparticles provide more protection for DNA.
Researchers developed nanoparticles that effectively halt amyloid beta aggregation and toxicity using ultra-low-energy X-rays. The innovative treatment strategy shows promise in delaying disease progression by up to 36% in preclinical models.
The Indian Institute of Science team developed a novel technique to fabricate structurally colored films with a liquid gallium metal and polydimethylsiloxane substrate. These films change color in response to mechanical deformation, showing potential applications in smart bandages, movement sensors, and reflective displays.
A new nanoparticle-based therapy using Luminol-conjugated cyclodextrin (LCD) nanoparticles has shown significant improvements in treating severe burn-induced intestinal barrier disruption. The therapy promotes the repair and regeneration of tight junction structures, reducing inflammation and oxidative stress.
Scientists have created a new approach for treating tendon-bone injuries by combining manganese silicate nanoparticles with cells to create an immunomodulatory scaffold. This innovation promotes integrated regeneration and functional recovery in patients, offering a promising solution for improving life quality.
Researchers developed a GPS nanoparticle platform that can home in on cancer cells to deliver gene-editing tools, targeting the protein implicated in tumor growth and spread. The technique may offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
The Access to Advanced Health Institute (AAHI) has received $12.7 million to develop a novel immune-stimulating adjuvant formulation, NanoAlum, which aims to improve vaccine protection against complex diseases like tuberculosis and influenza.
Researchers at MIT have developed a new type of nanoparticle that can both deliver vaccines and act as an adjuvant to generate a strong immune response. The particles, called metal-organic frameworks (MOFs), were shown to be effective in delivering the SARS-CoV-2 spike protein and boosting the immune system's response.
Rice University researchers have developed a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures. This allows for modifying the structure of the oxide layer, making the nanoparticles versatile tools for different applications.
Researchers are developing minimally invasive techniques to repair and regenerate tissue in aortic aneurysms using actively targeted, drug-releasing nanoparticles. The team found that rod-shaped particles with high aspect ratios were selectively taken up by diseased endothelial cells, leading to improved therapy outcomes.
Researchers have made a breakthrough in developing genetic treatments for hereditary conditions like cystic fibrosis and inherited vision loss. They created a new type of lipid nanoparticle, called Thio-lipids, that can deliver therapeutic payloads to the lungs and retina.
Researchers demonstrate a way to amplify interactions between particles to overcome environmental noise, enabling the study of entanglement in larger systems. This breakthrough holds promise for practical applications in sensor technology and environmental monitoring.
Researchers at the University of Pennsylvania have developed a new method to efficiently determine which lipid nanoparticles are likely to bind to the lungs, rather than the liver. This breakthrough enables targeted delivery of mRNA therapeutics beyond the liver, offering new hope for treatments of cystic fibrosis and lung cancer.
Researchers at the University of Pennsylvania School of Engineering and Applied Science have invented a new way to synthesize key components of lipid nanoparticles, simplifying their manufacture while boosting efficacy. The new method involves combining three chemicals to create branched lipidoids that promote mRNA delivery to target c...
A novel chemotherapy approach uses patient's own cells as Trojan horses to deliver targeted cancer-killing drugs to lung cancer cells. The method has shown promise in reducing tumor size and improving treatment efficacy with minimal collateral damage to healthy tissues.
A new study aims to enhance and prolong vaccine effectiveness by delivering adjuvants to white blood cells using lipid nanoparticles. The research, led by WVU professor Sharan Bobbala, has the potential to provide broader protection against evolving viruses and multiple diseases.
The VPNVax platform utilizes a modular approach to create viromimetic polymer nanoparticle vaccines with enhanced surface valence, demonstrating improved immune stimulatory effects. The research offers new insights into designing the next generation of VLP vaccines with increased durability and versatility.
Researchers have discovered a new way to target chemotherapy-resistant ovarian cancer cells by depriving them of cholesterol, leading to significant tumor growth reduction. The nanoparticles starve the cells of cholesterol, triggering cell death through oxidation of lipids in the cell membrane.
Scientists create 'μkiss' technique for precise delivery of materials to individual cells, offering new possibilities in single-cell science and next-generation therapeutic applications. The method provides full control over location, time, and scale of material application, enabling detailed studies of cellular processes.
Researchers at São Paulo State University developed a novel technique using lipid nanoparticles to administer lupeol, killing Leishmania protozoan parasites. The therapy eliminated parasites from organs in animal tests, reducing spleen and liver parasite numbers by 99.9% with minimal side effects.
A Husker research duo has won a $25,000 prize in the NIH’s Targeted Genome Editor Delivery Challenge. They will advance development of universal milk exosomes capable of transporting gene editors to any location in the body, overcoming a significant challenge in using gene editing to treat disease.
Researchers have developed a novel catalyst platform that enhances the selectivity of catalytic reactions by trapping nanoparticles to prevent agglomeration. The distance between particles plays a crucial role in determining the product yield, with increased separation leading to more efficient production of intermediate chemicals.
USC researchers have designed nanoparticles that can target and highlight cancer cells in lymph nodes, allowing for earlier detection of metastasis. The particles work by hitchhiking on immune cells to reach the lymph nodes, where they can amplify the signal detected by MRI scans.
Researchers from Pohang University of Science & Technology employ linker ions to pioneer three-dimensional microprinting technology applicable to inorganic substances and other various materials. The team successfully crafts inorganic porous structures with dimensions below 10 μm without specialized equipment.
A team of researchers has developed a novel mixing device that produces nanomedicines directly at the point of care, enabling rapid and cost-effective synthesis of personalized vaccines. The technology has potential implications for cancer therapies and infectious diseases.
Researchers have identified nanoplastics in ocean water off the coasts of China, South Korea, and the US, with surprising diversity in shape and chemical composition. The tiny plastic particles, originating from consumer products, were found to be more toxic than larger plastic particles due to their small size.
GIST researchers develop tunable optical properties in nanostructures, enabling applications in wound healing, drug delivery, and secure verification. A clock-inspired design featuring magnesium nano-rotamers demonstrates programmable polarization-resolved coloration.
Researchers developed a stable air-stable plasmonic reduction catalyst that enhances ethene production from acetylene using visible light. The catalyst achieves an efficiency of 320 mmol g<sup>−1</sup> h<sup>−1</sup> with 90% selectivity, surpassing known plasmonic and thermal catalysts.
A new technique developed at INRS pushes back some of the limits of infrared imaging for rare-earth doped nanoparticles. The SWIR-PLIMASC system enables high-sensitivity and high-speed imaging, allowing for accurate information to be derived from photoluminescence lifetimes.
Researchers at Washington University in St. Louis used specially made nanostructures to enhance the locust's ability to detect odors, boosting neural signals for improved chemical sensing. The team created a biocompatible and biodegradable nanoparticle that converts light to heat, amplifying neural activity.
Researchers develop nanofibrous matrices containing MXene nanoparticles to aid in muscle regeneration. The study reveals molecular mechanisms behind the effects of MXene nanoparticles on muscle growth, suggesting a promising avenue for treating volumetric muscle loss and muscle-related ailments.
Researchers at Brookhaven National Laboratory successfully produced large quantities of human ACE2 receptor protein in mouse cells, allowing for the study of viral receptors and potentially developing new therapies. The method could also facilitate the production of other complex proteins that have proven difficult to produce.
A team of researchers from MIT and the Broad Institute developed two types of injectable molecules called 'priming agents' that can boost DNA levels in blood samples, allowing for earlier cancer diagnosis and more sensitive detection of tumor mutations. The approach could also help improve detection of cancer recurrence.
Scientists develop novel synthetic strategy to create highly ordered colloidal crystals using DNA as the bonding element. The approach enables the synthesis of 10 new crystals with potential for designing metamaterials with unprecedented properties.
Researchers at TU Graz have made a breakthrough in manufacturing complex, free-standing 3D nanoarchitectures with precise shapes and sizes. They achieved this by precisely simulating the required optical properties in advance and completely removing chemical impurities, enabling new optical effects and application concepts.
Scientists have created a new therapy using nanoparticles to target specific immune cells responsible for allergic responses. The approach, which combines an allergen with antibodies that selectively inhibit mast cells, has shown promising results in a mouse study, preventing allergic reactions without causing side effects.
Researchers created nanoparticles using ultraviolet light crosslinked amino acids, loaded with doxorubicin and coated with tannic acid complex. The nanoparticles exhibited superior stability and drug release under different pH conditions, showing excellent anticancer activity in tumor-bearing mice.
Researchers developed nanosensors that can be inhaled and detected in urine, offering a potential alternative to CT scans for early lung cancer detection. The diagnostic system shows high specificity and sensitivity in detecting stage 1 or 2 lung tumors.
Researchers develop nanoparticles that selectively bind to activated astrocytes and microglia cells in the hippocampus of Alzheimer's patients, demonstrating increased nanoparticle transport across the blood brain barrier with age. The study provides valuable insights into advancing nanoparticle-based drug delivery for treating neurode...
Researchers developed a zinc oxide nanopagoda array photoelectrode with high electron conductivity, low defects, and enhanced visible light absorption properties. The addition of silver nanoparticles increased photocurrent by approximately 1.5-fold, improving water-splitting hydrogen production.
Researchers have developed nanodrones that target and eliminate cancer cells by recruiting natural killer cells to tumor sites. The study offers a potential solution for intractable types of cancers, with promising results in suppressing tumor growth without causing side effects.
Researchers at UPV and CSIC have developed a new method to generate metal nanoparticles for catalysts using microwave radiation. The process improves the sustainability and efficiency of catalysts by reducing temperatures and exposure times.
Scientists in Germany developed a new analytical method to precisely elucidate the size of particles, structure, and RNA molecules in pharmaceutical products. This information can help evaluate product quality, enabling improved development of new products.
Nanoparticles loaded with antibiotics and antimicrobial compounds inhibit TB progression and overcome resistance without cell damage. The technology shows promise for a shorter treatment strategy against multidrug-resistant strains of Mycobacterium tuberculosis.
A new method has been developed to produce green hydrogen more efficiently and cheaply, using ruthenium particles and a solar-powered electrolytic system. The technology could reduce the costs of green hydrogen production on an industrial scale.
Researchers from Japan Advanced Institute of Science and Technology have developed a copolymer-conjugated nanocatalytic system to enhance active electron transfer for increased photoinduced hydrogen generation. The system leverages the advantages of a stimuli-responsive polymer chain to achieve dynamic electron transfer.
A team of researchers has designed nanoparticles with a propeller shape to improve control over their movements. The chiral shape allows for stability and directionality, enabling cargo transport and manipulation, which can be useful for drug delivery and lab-on-a-chip systems.
Researchers developed novel nanoparticles that deliver RNA to microglia immune cells, reducing inflammation linked to Alzheimer's disease. The study showed a 42% reduction of PU-1 expression and multiple inflammatory markers in human cell cultures and mice models.