Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers create accurate tumor models using 3D bioprinting and a bioink made from Laponite, improving bonding and cross-linking capabilities. The study shows that Laponite enhances biological signaling in the tumor microenvironment, increasing cell viability and promoting anti-tumor drug development.
Macquarie University engineers have developed a new technique to make nanosensors using a single drop of ethanol, bypassing the need for high temperatures. The method improves efficiency and responsiveness, opening up new possibilities for the trillion-dollar global industry.
A breakthrough treatment targeting bone marrow cancer cells destroyed 90% of multiple myeloma cells in laboratory tests and 60% in human tissue samples. Researchers developed lipid-based nanoparticles containing RNA molecules that silence the CKAP5 gene, inhibiting cancer cell division.
Researchers developed a novel drug delivery system using polymersomes to target embryonic cells, reducing the need for higher doses of methotrexate. This breakthrough has promising results for managing ectopic pregnancies, potentially improving patient outcomes.
Researchers at the University of Missouri have developed a new type of nanoclay material that can be customized to perform specific tasks. This breakthrough could lead to advances in fields such as medical science, environmental science, and more.
Researchers discovered that nickel-cobalt alloy nanocrystals inhibit the activation of three inflammasomes, including NLRP3, NLRC4, and AIM2, in primary macrophages. The study found that these nanocrystals effectively treated colitis and acute peritonitis by reducing disease symptoms.
Researchers investigate how water molecules react with or on nanoparticle surfaces in aqueous solutions. They found that acidic conditions cause water molecules to split on hematite nanoparticles, while basic pH is required for anatase nanoparticles.
Researchers at NUS developed a new photodynamic therapy that selectively kills breast cancer cells without damaging surrounding tissues. The treatment uses a biocompatible silicone implant loaded with nanoparticles activated by near-infrared light, reducing the risk of toxicity and improving tumour control.
Researchers developed nanoparticles that mimic the glycocalyx pattern to treat inflammatory bowel disease. The treatment reduced symptoms and inflammation in mice with IBD, with specific versions showing significant improvement.
Scientists have teamed up to improve drug delivery by designing more effective lipid nanoparticles. Their latest study documents how high-throughput workflows can produce and characterize LNPs at record speed, with neatly ordered structures leading to better silencing of faulty genes in human neurons.
Researchers from Shinshu University develop a novel polymer interlocking mechanism to produce tough and additive-free latex films. The rotaxane-based strategy results in unusual crack propagation behavior, increasing tear resistance and preserving flexibility.
Researchers developed a fast and convenient method called polarized imaging dynamic light scattering (PIDLS) to evaluate nanoparticle size, morphology and distributions. The method uses optical sphericity to describe the degree of deviation from spheres and provides statistical morphological distribution.
A team of chemists at UC Riverside has discovered that the distribution of a magnetic field is itself chiral, allowing for the rapid formation of chiral structures. This method has potential applications in sensing and anti-counterfeit technology, such as detecting chiral or achiral molecules linked to certain diseases.
Researchers developed a biodegradable nanoparticle that reaches dendritic cells in mice with melanoma and colon cancer, activating an immune response. The nanoparticle improves survival rates for these cancers, with half of mice surviving long-term after treatment.
A study by the University of Helsinki found that oxidized organic molecules from Amazon rainforests contribute to the formation of aerosol particles in the tropical free troposphere. These molecules, primarily composed of isoprene, can nucleate or condense on nanoparticles, impacting cloud formation and global climate.
Researchers have developed a new approach to treating tumors using 'self-immolative' polyferrocenes that trigger a fatal cycle of oxidative stress in cancer cells. In experiments, these copolymers inhibited tumor growth with negligible side effects, offering potential for chemodynamic therapy.
Researchers have created an RNA nanoparticle therapy that disables the pathways through which multiple myeloma cells travel, stopping their spread. The therapy targets the microenvironment of the cancer and prevents the production of a protein that attracts cancer cells to blood vessels.
Researchers at Karolinska Institutet have developed a new method called single-particle profiling (SPP) to study bioparticles in health and disease. The SPP enables the measurement of thousands of particles between 5 and 200 nanometres in size, with potential applications in vaccine development and creating more effective nanocarriers.
Researchers have developed a therapy using nanocarriers engineered from adult skin cells that curb inflammation and tissue injury in damaged mouse lungs. The treatment has shown promise for treating acute respiratory distress syndrome (ARDS), a condition that leads to respiratory failure and puts patients on ventilators.
Researchers at Ulsan National Institute of Science and Technology have made a breakthrough in creating ultra-photostable avalanching nanoparticles that can perform unlimited photoswitching. This achievement has significant implications for fields like optical probes, 3D optical memory, and super-resolution microscopy.
Researchers have developed a fully photostable and photoswitchable nanoparticle that can be controlled indefinitely using near-infrared light. This breakthrough has the potential to revolutionize fields such as optical memory, super-resolution microscopy, and bioimaging.
Ben-Gurion University researchers have discovered a new principle in optics using the Pacific Cleaner Shrimp, leading to the creation of an ultra-thin and highly efficient whitening material. The study found that the shrimp's unique arrangement of molecules creates birefringent nanospheres with brilliant whiteness.
Research finds that E171 nanoparticles are rapidly absorbed through the buccal cavity, causing oxidative stress and damaging DNA in human oral epithelial cells, potentially affecting cell regeneration
Researchers have identified a new mechanism of communication between fat cells, opening up avenues for novel obesity treatments. The discovery centers on tunnelling nanotubes, which allow distant cells to communicate directly and transfer cargos.
A new edible CBD coating has been developed to increase the shelf life of strawberries by reducing microbial growth. The coating, made with encapsulated CBD nanoparticles, was found to preserve berries for up to 15 days while maintaining their color and antioxidant activity.
Researchers discovered that air pollution particles trigger autophagy, a cellular defense process, which has an upper threshold and may reduce its effectiveness against other threats. This finding provides new insights into the link between air pollution and lung disease.
Researchers at Northwestern University developed a metal-filtering sponge that can capture and recover critical metals and heavy-metal pollutants from contaminated water. The new sponge successfully removed lead to below detectable levels with one use and recovered over 90% of the ions during subsequent cycles.
A novel protein nanoparticle vaccine candidate using adjuvants has been developed to boost effectiveness against viral infections. The study found that the vaccine provided complete protection against influenza viral challenges.
A new study reveals a shared molecular response to nanoparticles, linking immune activation and particulate matter exposure. The findings propose a solution to the 'one-chemical-one-signature' problem in chemical safety assessment.
A team of researchers from the University of Oklahoma and Yale University has developed a super-resolution imaging platform technology to visualize nanoparticles within cells. The technique, called expansion microscopy, enables 3-D imaging with resolutions as low as 10 nanometers, allowing for safer and more efficient nanomedicines.
Researchers at the University of Minnesota have developed a new diagnostic technique called Nano-QuIC, which significantly improves protein-misfolding detection methods. The method reduces detection times from 14 hours to just four hours and increases sensitivity by a factor of ten.
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
Researchers from TIFR Hyderabad create molecular strainers that can filter particles as small as hydrogen molecules, offering a new basis for designing more efficient filtration processes. The study's findings provide insights into the movement of molecules through sieves and open up avenues for further exploration in industries.
Researchers have developed a new approach to constructing thermoelectric modules using silver nanoparticles, enabling efficient energy conversion and operation across various temperatures. The discovery is expected to accelerate the development of advanced modules for power generation and other applications.
Researchers demonstrate probabilistic computing's capabilities by simulating networks of stochastic nanodevices to solve specific NP problems. The simulations agree with theoretical solutions, indicating the potential for scaling up this approach.
Scientists have identified a novel mechanism of gel formation in synthetic polymers, which leads to the creation of worm-like structures. This breakthrough has significant implications for biofabrication and could lead to the development of new medical implants, contact lenses, and other applications.
A new type of floatable photocatalytic platform composed of hydrogel nanocomposites efficiently proceeds hydrogen evolution reaction. The platform exhibits clear advantages over conventional systems, including efficient solar energy conversion and easy gas diffusion.
Physicists at ANU developed nanoparticles to increase the frequency of light that can be seen by cameras, enabling analysis of tiny objects down to one billionth of a meter. This technology could help create microscopes with higher resolution and mitigate issues associated with conventional optical and electron microscopy.
Researchers in China developed a method to increase the efficacy of membrane separation technology using nanofibrous membranes with silver nanoparticles. The technology is up to 99% effective at separating oil from water, promoting a stable hydration layer that impedes oil droplets and enhances antibacterial properties.
A two-component system designed by MIT engineers has shown promising results in stopping internal bleeding in mouse models. The system, which mimics the body's natural clotting process, uses a nanoparticle and polymer to recruit platelets and form blood clots at injury sites.
Researchers at EPFL have developed a novel imaging technique using cryogenic transmission electron tomography and deep learning to visualize the nanostructure of platinum catalyst layers in fuel cells. This breakthrough reveals the heterogenous thickness of ionomer, a crucial component that influences catalyst performance.
Researchers have developed a novel insulin formulation that can be switched on by glucose, offering improved regulation of blood sugar levels in patients with type 1 diabetes. The new formulation uses biocompatible lipid nanoparticles and achieves precise control of insulin release in response to fluctuations in blood sugar.
Researchers at Tokyo Institute of Technology developed a simple sol-gel method to synthesize highly pure bifunctional solid acid-base catalysts with desirable properties. The new method produces SrTiO3 nanoparticles with high surface area, showing 10 times higher catalytic activity than commercially available titanates.
Researchers at Tokyo University of Science have developed a novel platinum nanocluster catalyst that exhibits 2.1 times higher oxygen reduction reaction activity than commercial catalysts. The study reveals that the high activity is due to the electronic structure of surface Pt atoms, which is suitable for ORR progress.
Researchers developed a chelator-free-radiolabeled polymersome capable of long-term multiday PET imaging in vivo. The nanovesicle meets key requirements for targeted cancer therapy, including precision targeting, stable radiotracer binding, and biocompatibility.
A novel Cu-based catalyst with improved catalytic performance for CO2 reduction has been developed by leveraging strong metal-support interactions and defect sites cooperativity. The DFNS/TiO2-Cu catalyst showed excellent activity and stability, outperforming other copper-based thermal catalysts.
A new type of meta-optics, developed at Harvard, has been successfully tested at Graz University of Technology, allowing the observation of ultra-fast physical processes. The lens uses extreme ultraviolet radiation to track charge carriers in space and time, enabling optimization of modern transistors and optoelectronic circuits.
A team of researchers has observed nanoparticles self-assembling and crystalizing into solid materials in real time, revealing the growth process at nanometer resolution. The findings have implications for designing new materials, including thin films for electronic applications.
Researchers have developed a new type of nanoparticle that can efficiently deliver CRISPR/Cas9 components to the lungs, allowing for targeted gene editing. In mice studies, the particles delivered mRNA to up to 60% of lung epithelial cells, offering a promising approach to treating genetic diseases such as cystic fibrosis.
For the first time, scientists have observed nanoparticles forming crystals with unprecedented clarity. The study used optimized liquid-phase transmission electron microscopy to capture the self-assembly process of thousands of nanoparticles. This breakthrough could lead to designing new materials for electronic applications.
Researchers have developed a novel technology for nanoencapsulation of bioactive compounds, specifically anthocyanin, using pectin and lysozyme. The methodology ensures slow release of the compound, allowing it to survive gut bacteria and digestive enzymes.
Researchers have developed a practical method to generate green hydrogen using natural enzymes, which contain only earth-abundant elements. The new approach enables the efficient production of green hydrogen from sunlight, making it a promising solution for decarbonizing transportation and industries.
The study investigates the atomic flow behavior during joint formation, exploring processing time, temperature, and stress distribution on nanojoints. The results reveal that local stress and capillary interactions significantly impact joint quality, leading to advances in industrial applications of Ag nanowire interconnect networks.
Corneal graft rejection can be as high as 10% due to poor patient compliance with medications, which require frequent eyedrop administrations. Researchers at Virginia Commonwealth University developed nanoparticles to encapsulate eye medication, decreasing graft rejection while requiring fewer and smaller doses. The approach reversed s...
Georgia Institute of Technology researchers have developed a new treatment for lymphedema using nanoparticles that can repair lymphatic vessel pumping. The approach delivers a drug to help lymphatic vessels pump, targeting the problem rather than regrowing new vessels.
A team of researchers at KAUST has developed a biological method to produce size-controlled palladium nanoclusters anchored on the surface of Geobacter sulfurreducens, outperforming benchmark catalysts in water-splitting reactions. This eco-friendly approach could provide a sustainable solution for high-performance catalysis.
A team of researchers developed a novel cancer therapeutic combining antibody fragments with molecularly engineered nanoparticles, permanently eradicating gastric cancer in treated mice. The 'hit and run' drug delivery system targets HER2 proteins associated with gastric cancer.
A team of researchers has discovered a simple way to deliver cancer therapeutics to tumor cells by fluidizing the cell membrane using lipid nanoparticles containing EDTA. The mechanism is independent of metal chelation properties and involves changing the characteristics of the cell membrane to promote nanoparticle uptake.
Researchers from Swansea University and Université Grenoble Alpes demonstrate the effectiveness of selenium nanoparticles in killing ovarian cancer cell models. The study reveals a novel biological mechanism underlying the anti-cancer effect, involving histone methylatransferases and epigenetic processes.
Researchers from ETH Zurich have achieved groundbreaking cooling of a glass nanoparticle along two directions of motion, overcoming the 'Dark Mode Effect'. This breakthrough enables the creation of fragile quantum states and paves the way for ultrasensitive gyroscopes and sensors.