New nanoparticles aid sepsis treatment in mice
Researchers developed nanoparticles that deliver NAD(H), a molecule with anti-inflammatory properties, to treat sepsis in mice. The treatment improved survival rates and prevented multiorgan injury.
Nanoparticles
Articles tagged with Nanoparticles
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Engineers develop nanoparticles that cross the blood-brain barrier
A team of MIT researchers has developed drug-carrying nanoparticles that can efficiently penetrate the brain and kill glioblastoma cells. Using a human tissue model, they showed that the particles could get into tumors and deliver chemotherapy drugs, including cisplatin, which effectively killed tumor cells.
Understanding the health and environmental risks of microplastics
Researchers investigate microplastic risks using nanotoxicology lessons, standardizing particles for reproducible studies. Scientists aim to replicate real-world situations in lab simulations to understand human gut and lung cell effects.
Light instead of electricity: A new kind of “green hydrogen”
Scientists at TU Wien have developed a new photocatalyst design that can split water into hydrogen and oxygen using sunlight. This process, called photocatalytic water splitting, has the potential to produce environmentally friendly 'green hydrogen' with higher efficiency than traditional electrolysis methods.
Herbal supplement shows promise against lung cancer
A recent study published in Pharmaceutics suggests that berberine can suppress the proliferation of lung cancer cells, reduce airway inflammation, and modulate genes involved in inflammation. The researchers used liquid crystalline nanoparticles to enhance safety and effectiveness.
A sunlight-driven “self-healing” anti-corrosion coating
A new 'self-healing' anti-corrosion coating has been developed, which can repair microcracks and protect metal from erosion under solar irradiation. The coating's performance is verified to be maintained above 99% regardless of the repair, making it suitable for outdoor facilities.
WashU engineers developing therapy to regenerate blood vessels, muscle with NIH grant
A team of engineers is working on a novel treatment using nanoparticles carrying therapeutic proteins to promote regeneration of blood vessels and muscle in injured limbs. The approach, which has shown promising results in animal models, aims to treat critical limb ischemia, a condition that can lead to amputation or death.
A nanoparticle and inhibitor trigger the immune system, outsmarting brain cancer
Researchers at Michigan Medicine developed a nanoparticle-based inhibitor that successfully triggers the immune system to eliminate brain tumors in mouse models. The approach breaks the shield built by glioma cells around the immune system, allowing the immune cells to attack and delay tumor progression.
Thermal insulation for quantum technologies
Scientists at HZB created sintered porous silicon-aluminum nanomaterials with reduced thermal conductivity using a novel process. The resulting materials have tiny pores, crystalline nanoparticles, and domain boundaries that suppress heat conduction.
Magnetic nanoparticles in biological vehicles individually characterized for the first time
A multidisciplinary research group uses magnetotactic bacteria to create nanomagnetic structures, which can be steered through the human body via external magnetic fields. They have developed a new method to measure the magnetic properties of individual nanomagnets in biological entities, enabling precise control over these structures.
Tiny bots that can deep clean teeth
Researchers at IISc and Theranautilus have developed nano-sized robots that can manipulate using a magnetic field to kill bacteria in dentinal tubules, improving the success rate of root canal treatments. The nanobots were able to penetrate further than previous methods, providing a safer alternative to harsh chemicals or antibiotics.
Generating ultra-violet lasers with near-infrared light through “domino upconversion” of nanoparticles
A research team developed a new approach to generate deep-ultraviolet lasing through a 'domino upconversion' process of nanoparticles using near-infrared light. This breakthrough enables the construction of miniaturised high energy lasers for bio-detection and photonic devices.
Study finds nanomedicine targeting lymph nodes key to triple negative breast cancer treatment
Researchers found that targeting both tumor and lymph node microenvironments with nanomedicine improves treatment response for metastatic triple negative breast cancer. Long-term tumor remission was achieved in mice models using nanoparticles to deliver immune-modulating drugs.
Minerals can be key to healing damaged tissue
A collaboration between researchers identified crucial minerals regulating gene expression to control tissue renewal and growth. Minerals such as silicon, magnesium, and lithium induce endochondral ossification by turning on key genes, leading to the transformation of stem cells into bone cells.
YVO₄: Nd³⁺-based nanotheranostic agent for imaging and therapy of orthotopic gliomas
Researchers developed a core-shell structured nanotheranostic agent (YVO₄:Nd³⁺-HMME@MnO₂-LF) for orthotopic glioma imaging and therapy. The YVO₄ core exhibits NIR-II fluorescence properties, while the MnO₂ shell releases Mn²⁺ ions for T₁-weight MRI and provides O₂ in tumor microenvironments to enhance sonodynamic therapy.
Using sound to control enzymatic reactions
A team of scientists successfully controlled multistep enzyme reactions using audible sound, creating a new method for spatiotemporal regulation. The researchers used standing waves generated by sound to separate and compartmentalize solutions, allowing for the precise control of chemical reactions.
Metamaterial significantly enhances the chiral nanoparticle signals
A research team developed a technology to increase chirality between light and nanoparticles using metamaterials, significantly strengthening the signal. This allows for the accurate structural analysis of chiral nanoparticles with high precision.
Researchers shed light on why a certain plant virus is so powerful at fighting cancer
A team of researchers has discovered that cowpea mosaic virus, when injected into a tumor, triggers a powerful immune response, preventing cancer recurrence. The unique protein shell and RNA structure of the virus activate toll-like receptors, leading to increased cytokine production and a prolonged anti-cancer response.
Green technology breakthrough: Hematite photocatalyst using sunlight energy simultaneously produces hydrogen and hydrogen peroxide
A breakthrough in green technology has successfully produced both hydrogen gas and hydrogen peroxide simultaneously from sunlight and water using a hematite photocatalyst. This innovation could lead to a solar water-splitting utilization system with greater added value, enabling the widespread adoption of carbon-neutral energy sources.
It’s a dirty job, but some catalyst has got to do it
Researchers aim to improve stability and efficiency of catalytic materials using quantum mechanics-based calculations and computational simulations. The goal is to create more effective catalysts that reduce pollution and energy consumption.
Nanoclusters self-organize into centimeter-scale hierarchical assemblies
A Cornell-led project has created synthetic nanoclusters that can mimic the hierarchical self-assembly of natural systems, from DNA to butterfly wings. The resulting thin films have perfect periodic patterning and chiral optical properties, opening up new avenues for developing technologies inspired by nature.
Nylon cooking bags, plastic-lined cups can release nanoparticles into liquids
A new study found that nylon cooking bags and plastic-lined cups can release trillions of nanometer-sized particles into each liter of water they come into contact with. The levels of these particles are below regulatory limits for consumption, but still pose a potential health risk.
NIST study shows everyday plastic products release trillions of microscopic particles into water
Researchers analyzed food-grade nylon bags and single-use beverage cups, finding that they release trillions of nanoparticles per liter when exposed to hot water. The average size of these nanoparticles was between 30-80 nanometers, with concentrations seven times higher from nylon bags than from beverage cups.
Nanoparticles can cross the placenta during pregnancy, potentially exposing fetus
Rutgers scientists found that inhaled nanoparticles can migrate from the lungs to the placenta and possibly fetal tissues after maternal exposure throughout pregnancy. This discovery raises concerns about the potential health effects of nanoparticle exposure on human fetuses.
Nanoparticles developed at OSU show promise for locating, removing endometriosis lesions
Scientists at OSU have developed a new nanotechnology approach for locating and removing endometriosis lesions using magnetic nanoparticles. These particles accumulate in lesions, making them easier to see via MRI, and can be heated to high temperatures, allowing for safe removal through non-invasive procedures.
Nanoparticles prove effective against the yellow fever mosquito
Researchers at Ohio State University discover that carbon black nanoparticles are fatal to yellow fever mosquito larvae in standing water. The material accumulates on the larvae's head, abdomen, and gut, blocking basic biological functions.
Feel the attraction of zwitterionic Janus Particles
A team of researchers used a new computer simulation to model the electrostatic self-organization of zwitterionic nanoparticles, which are useful for drug delivery. They found that including transient charge fluctuations greatly increased the accuracy, leading to the development of new self-assembling smart nanomaterials.
Seeing more deeply into nanomaterials
Researchers at Columbia Engineering and Brookhaven National Laboratory have developed a new high-resolution x-ray imaging technique to reveal the inner structure of novel nanomaterials. The tool, which provides 7nm resolution, has enabled them to study complex 3D architectures with unprecedented detail.
Nanoparticles could enable a more sensitive and durable rapid COVID-19 test
Researchers have developed a rapid COVID-19 test that uses molecularly imprinted polymer nanoparticles to detect SARS-CoV-2. The new test is more sensitive and works under extreme conditions than existing antibody-based tests, with preliminary results indicating it can detect a 6,000-times lower amount of the virus.
Decoy particles trick coronavirus as it evolves
Researchers have developed a new potential COVID-19 treatment using decoy nanoparticles that mimic cells. These nanoparticles effectively inhibit viruses and bind them, rendering them inactive. The treatment has shown promise against drug-resistant variants, outperforming traditional treatments in some cases.
Microcavities as a sensor platform
Researchers at University of Innsbruck and ETH Zurich propose a new concept for a high-precision quantum sensor using microcavities and levitated nanoparticles. By exploiting fast unstable dynamics, they demonstrate mechanical squeezing reducing motional fluctuations below zero-point motion.
Turmeric compound helps grow engineered blood vessels and tissues
Researchers at UC Riverside have discovered that curcumin promotes vascular endothelial growth factor (VEGF) secretion, helping to grow engineered blood vessels and tissues. The study uses magnetic hydrogels coated with curcumin-coated nanoparticles, which gradually release the compound without injuring cells.
Newly identified neutrophil subset is a promising therapeutic target
Researchers at the University of Illinois Chicago have identified two distinct subtypes of neutrophils, with one subtype being a drug target for treating inflammatory diseases. The discovery paves the way for more targeted therapies that address chronic inflammation without suppressing anti-infection functions.
Sugar-coated nanoparticles target macrophages, reverse pulmonary fibrosis
Scientists create nanoparticles coated in mannose to block production of scar-promoting protein in lung cells. The treatment holds promise for preventing severe lung scarring disease.
The nanodrug that attacks the cancer twice A single nanoparticle does two jobs: enhancing the effectiveness of chemotherapy and reinvigorating the immune system
Researchers at Tel Aviv University developed a drug delivery system based on lipid nanoparticles that utilize RNA to boost personalized cancer care. The nanodrug enhances chemotherapy effectiveness and reinvigorates the immune system, increasing sensitivity to cancer cells.
Scavenger nanoparticles could make fuel cell-powered vehicles a reality
Engineers at University of Illinois Chicago develop additive material to make inexpensive iron-nitrogen-carbon fuel cell catalysts more durable. The material scavenge and deactivate free radicals, reducing corrosion and degradation in fuel cells.
X-rays help scientists uncover new forms of material using designer DNA
Researchers use DNA to program metal nanoparticles to assemble into new configurations, resulting in the discovery of three new crystalline phases. The approach enables symmetry breaking and creation of complex colloidal crystal structures with unique optical and catalytic properties.
Researchers create a sea of nano-sized gold stars
A team of researchers from PNNL and UW successfully designed a bio-inspired molecule that directs gold atoms to form perfect nanoscale stars. The work is an important step toward understanding and controlling metal nanoparticle shape and creating advanced materials with tunable properties.
Engineering researchers develop porous nanoparticles for regenerative medicine
Scientists at Texas A¼M University have created water-stable, 2D covalent organic framework nanoparticles that can guide human mesenchymal stem cells to form bone tissue. The new technology has the potential to impact the treatment of bone regeneration and improve drug delivery.
'Translating' nanoparticles for biomedical applications
The study demonstrates the potential of using 'translating' nanoparticles to facilitate communication between bacteria and yeast, enabling applications in medicine, agriculture, and synthetic biology. The team's findings pave the way for regulating interactions between bacteria and human cells.
Stabilizing emulsion research improves firefighting operations and more
The team's research uses graphene quantum dots with zwitterionic properties to stabilize Pickering emulsions, allowing for controlled release and improved durability in firefighting operations. This technology holds promise for enhanced oil recovery and drug delivery.
Growing extremely tiny, uniformly sized diamonds — without explosives
Researchers have created ultra-uniform nanodiamonds using a new chemical process that mimics the conditions found in natural diamond formation. The tiny crystals are crucial for drug delivery, sensors, and quantum computer processors. With this breakthrough, scientists can now control single atoms within larger structures.
An improved ink for colon tattoos
Researchers have created a new type of colon tattoo ink that is more biocompatible and less prone to diffusion than existing inks. The ink uses metal-derived nanoparticles and polymers to adhere to the submucosal surface in the colon, allowing for better identification and removal of complex polyps and tumors.
Quantum dots shine bright to help scientists see inflammatory cells in fat
Researchers at the University of Illinois created quantum dots to visualize macrophages in fat tissue, shedding light on chronic inflammation's role in diseases. The new technology enables accurate cell counting and tracking over time, offering a potential diagnostic tool for insulin resistance and metabolic syndrome.
Thomas Senftle wins NSF CAREER Award
Engineer Thomas Senftle at Rice University has won a prestigious NSF CAREER Award to improve catalysts through machine learning. He will develop open-source models to speed up the development of catalysts with optimized particle/support combinations, aiming to reduce unwanted molecules in water.
Getting bacteria and yeast to talk to each other, thanks to a ‘nanotranslator’
Scientists develop first system allowing two unrelated organisms to communicate via chemical signals, with potential applications in disease treatment and cell behavior modification. The nano-translator uses silica nanoparticles to react with glucose and phleomycin, enabling bacteria and yeast to exchange messages.
Treating cancer with light-sensitive nanoscale biomaterials
Researchers review current status of nanoparticle-enhanced photothermal therapy and photodynamic therapy, combining the two techniques to achieve highest treatment efficiency. Nanoparticles can deliver drugs or antibiotics to inaccessible sites, creating a more powerful treatment method.
Acoustic propulsion of nanomachines depends on their orientation
Physicists simulate acoustic propulsion of freely orientable nanoparticles by traveling ultrasound waves, finding that particle orientation affects propulsion. The study reveals important properties of acoustically propelled nanoparticles suitable for biomedical applications.
Lower, more frequent doses of nanomedicines may enhance cancer treatment
Researchers at Massachusetts General Hospital found that using nanomedicines at lower, more frequent doses can normalize the tumor microenvironment and improve cancer treatments. The study showed that this approach can help correct abnormalities that protect tumors and improve blood vessel function and immune activation within a tumor.
Nanoparticle reduces skin and lung scarring for scleroderma, mouse study finds
A biodegradable nanoparticle has shown promise in reducing skin and lung scarring in mice with scleroderma. The treatment targets specific immune cells responsible for the disease's chronic inflammation and scarring.
Atom by atom: building precise smaller nanoparticles with templates
Scientists have created a supramolecular template using dendron-assembled structures to synthesize quasi-sub-nanoparticles with controlled atomicity. This approach offers a cost-effective and versatile method for producing a variety of nanostructures.
A ‘greener’ way to clean wastewater treatment filters
Scientists have created a 'greener' way to clean wastewater treatment filters by using glucose-based nanoparticles, which effectively remove contaminants without destroying the membrane. The new system is more cost-effective and environmentally friendly than traditional methods.
Seeing below the surface of bimetallic nanoparticles
Researchers from Osaka University report a new technique for tracking the synthesis of core–shell bimetallic nanoparticles in real time, allowing for fine-tuning of nanomaterial preparation. The technique uses a piezoelectric resonator to monitor particle shape changes and track interdiffusion of metals.
New electrode on board: zinc blende type β-SiC anode materials for lithium-ion batteries
Scientists have developed a simple methodology for synthesizing novel β-SiC nanoparticle-based anode materials for lithium-ion batteries. These materials exhibit high current density, rated capacity and promising compatibility for reversible lithium-ion storage.
Nanocarrier spray: Better crops without genetic modification
Researchers at RIKEN CSRS have developed a non-transgenic method to modify plant genes using a bioactive molecule spray, which can be used to improve crop yield and resistance to pests. The technique has shown promising results in improving economically desirable quality traits in crops.
Development of nanoengineered bacteria for cancer optotheranostics
Scientists at Japan Advanced Institute of Science and Technology have created nanoengineered bacteria for photothermal cancer immunotheranostics. The synthesized nanoparticles showed powerful photothermal conversion, high biocompatibility, and excellent tumor selectivity, facilitating clear fluorescent tumor visualization.
Easy aluminum nanoparticles for rapid, efficient hydrogen generation from water
Researchers at UCSC developed a simple method to make aluminum nanoparticles that split water and generate hydrogen gas rapidly. The gallium-aluminum composite creates aluminum nanoparticles that react with water at room temperature, yielding large amounts of hydrogen.
CPRIT supports work on combo cancer therapy
Rice University's Gang Bao receives $1 million CPRIT grant to develop a three-pronged strategy combining magnetic nanoparticles, free radical generation, and immune checkpoint blockade to kill cancer cells. The approach aims to increase the efficacy of cancer therapy, potentially leading to a clinical trial.
Size matters in particle treatments of traumatic injuries
Researchers at MIT have performed a systematic study on how different-sized polymer nanoparticles circulate in the body and interact with platelets to stop bleeding. They found that intermediate-sized particles (150 nanometers) were the most effective, with less likelihood of accumulating in off-target sites.
Novel nanoparticles target gene therapy directly into the lungs
Scientists at Tufts University create nanoparticles that carry genetic instructions to specifically target the lungs, reducing tumors in a preclinical model of a rare genetic lung disease. The breakthrough could lead to improved treatment options for patients with lymphangioleiomyomatosis.