Researchers have demonstrated the effectiveness of polymer-coated nanoparticles in delivering drugs to the brain, overcoming the blood-brain barrier challenge. The study showed that zwitterionic polymers improve accessibility but are rapidly absorbed by blood vessel walls.
Researchers at Seoul National University explored the effects of oxygen doping on magnetite nanoparticles. They observed an intriguing variation in the Verwey transition temperature and proposed a diffusion model to explain this phenomenon.
Scientists have developed a method to synthesize nanocrystals in live cells through space-time coupled synthesis, enabling the creation of super biosystems. This approach has been successfully applied to various cell types, including yeast, bacteria, and mammalian cells.
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A multidisciplinary team of researchers used a new X-ray technique to discover zinc-containing nanoparticles lodged within the wooden hull of the Mary Rose, leading to its deterioration. The nanoparticles, likely from anaerobic bacteria, have been found in conjunction with polymer deposits that were added to preserve the ship's remains.
Researchers developed a flexible, self-powered device that translates sound waves into electrical signals, mimicking the inner ear's function. The device, implanted in a model ear, accurately recreated music files, offering a promising solution for treating hearing loss without batteries.
Researchers at Duke University developed electrochromic technology that can alternate between harvesting heat from sunlight and allowing an object to cool. The device, which uses a thin layer of graphene and metal nanoparticles, demonstrates a tuning range of thermal radiation never seen before.
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A study by the University of Pennsylvania and Indiana University found that a nanozyme therapy, combining ferumoxytol and hydrogen peroxide, significantly reduced the buildup of harmful dental plaque and targeted bacteria responsible for tooth decay. The treatment effectively killed Streptococcus mutans bacteria while leaving other ora...
Researchers at USTC have successfully synthesized small-sized Pt intermetallic nanoparticle catalysts with ultralow Pt loading and high mass activity. These catalysts exhibited excellent electrocatalytic performance for oxygen reduction reaction in proton-exchange membrane fuel cells, potentially decreasing the cost of fuel cells.
A research team developed a new material platform by transferring chirality from molecular to microscale through self-assembly. The resulting chiral nanomaterials exhibit broad optical activity in the short-wave infrared region, enabling applications such as infrared neural stimulation and imaging.
Researchers have developed nanoparticles that can communicate with and slow the development of cancer cells. The nanoparticles aggregate in cancer cells, reducing metabolic activity and growth, and are activated by MMP-9 enzyme secreted by cancer cells.
The study utilizes gas-phase electrophoresis (GEMMA) to separate nanovesicles from proteins in natural samples. This allows for accurate attribution of effects to transport vesicles, crucial for understanding cellular communication and metabolism. The method has significant implications for extracellular vesicle research and its releva...
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Scientists have found that adding a single atom to rutile titanium dioxide can create oxygen vacancies, leading to more stable local structures and controlling reaction stability. This discovery could lead to new ways of understanding the relationship between material structure and function.
Researchers have developed a new approach to deliver therapeutic nucleic acids using nanoparticles coated with antibodies. This system targets cancer cells while sparing normal cells, showing improved efficacy and reduced toxicity compared to previous methods.
Liquid marbles' unique hydrophobic outer layer allows for faster evaporation than bare water droplets due to particle-particle and liquid-particle interactions. The team's mathematical model accurately predicts evaporation behavior, providing insights into these tiny biological structures.
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Researchers found that nanosilver treatment can increase the risk of recurrent infections when used long-term due to pathogen adaptation. Long-term exposure allows bacteria like Pseudomonas aeruginosa to evolve and resume normal growth upon discontinuation of treatment.
A team of scientists created a uniform protein nanoparticle, TIP60, with a diameter of 22 nm, which can be modified to target specific molecules. The 3D structure of TIP60 was elucidated using cryo-electron microscopy, revealing an icosahedral 60-meric structure with porous properties.
Researchers use high-intensity X-rays to study a single catalyst nanoparticle's surface changes during chemical reactions. The study reveals how the surface composition affects activity, shedding light on industrial catalytic materials.
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Researchers developed a fluorescence quenching assay to probe the integrity of cell membrane coating on biomimetic nanoparticles. The study found that only 20% of particles were fully coated, indicating significant limitations in current coating protocols.
Researchers developed nanoscale insecticidal hair coating for prolonged anti-lice protection, reducing re-treatments and side effects. The coating, formed using halloysite nanotubes, retains its protective properties after washing the animal's hair.
Researchers at North Carolina State University developed a simple, cost-effective method to deposit liquid metal copper alloy nanoparticles onto fabrics, creating an effective antiviral and antimicrobial coating. The coating eradicated over 99% of pathogens, including bacteria, fungi, and viruses, within five minutes.
Researchers have developed a microneedle patch that delivers a COVID-19 DNA vaccine into the skin, causing strong immune responses in cells and mice. The patch can be stored at room temperature for over 30 days, making it an important tool for global COVID-19 vaccine distribution.
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A team of researchers from IOCB Prague has discovered a new type of nanoparticles capable of safely transporting various types of nucleic acids used for therapeutic purposes into cells. The universal nature of their system sets it apart from existing solutions, allowing for efficient transport of mRNA and other RNA molecules into cells.
Researchers have developed an AI-powered platform that allows scientists to grow virtual tumors and optimize nanoparticle designs using artificial intelligence. The new EVONANO platform has the potential to improve targeted cancer treatments, enabling personalized therapies for individual patients.
Scientists at Hokkaido University have developed a lipid nanoparticle that delivers immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy. This approach has shown promise in mice experiments and could lead to the development of an adjuvant treatment for cancer patients.
A new gene delivery system promotes healing in rat models by preventing inflammation and bone degradation after tooth replantation. The study found that teeth treated with the system showed significantly greater dental root thickness and fewer osteoclasts, leading to improved success rates.
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Scientists discovered hot-band absorption (HBA) in FDA-approved Indocyanine Green, enabling advanced anti-Stokes fluorescence bioimaging. HBA-based ASF has high thermal sensitivity and allows for IR perception, making it suitable for applications such as tumor detection and blood vessel imaging.
Researchers developed a treatment using cowpea mosaic virus nanoparticles that target lung tumors, slowing tumor growth and preventing cancer spread. The treatment showed efficacy against aggressive cancer cell lines and may offer protection to patients at high risk of metastatic disease.
Researchers at Goethe University Frankfurt and Bonn have synthesized molecular nano spheres made of silicon atoms, known as silafulleranes, which can encapsulate chloride ions. The discovery of these new compounds may lead to improved applications in electronics, solar cells, and batteries.
Researchers at the University of California - San Diego have developed COVID-19 vaccine candidates made from plant viruses and bacteriophages, which can be stored and shipped without refrigeration. These vaccines trigger high production of neutralizing antibodies in mice, offering a potential solution for global distribution efforts.
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The COgITOR project aims to develop an initial prototype for an autonomous liquid cybernetic system that can be used as an intelligent, active probe in extreme areas. The system will be composed of concentric spheres containing solvents enriched with nanoparticles and a silicon chip in the centre.
Researchers developed an AI tool that can quickly and accurately identify suspicious proteins in the body by analyzing their movements. The method, known as diffusional fingerprinting, uses machine learning algorithms to predict protein behavior with over 90% accuracy.
Scientists from the University of Melbourne and MIT have discovered a simple mechanical tube method to measure nanoparticle mass and size simultaneously. This breakthrough enables the simultaneous measurement of these properties, which is crucial for various applications such as drug delivery and nano-optics.
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Researchers at IBS developed a novel composite material consisting of metal nanowires within an ultrathin rubber film. The float assembly method creates a monolayer of nanowires in the rubber film, resulting in excellent physical properties such as high stretchability and metal-like conductivity.
Researchers from University of Science and Technology of China have quantified the critical particle distance to inhibit metal sintering in catalysts. The study found that adjusting particle spacing can significantly impact sintering, with PMC dominant at short distances and OR dominant at long distances.
A novel method for imaging vibrations and movements of atoms in catalysts has been developed by a collaboration of internationally leading researchers. The new analytical method reveals a dynamic behavior of the atoms, contrary to the long-held expectation that atoms in nanoparticles are static during observations.
Researchers developed a protein-based COVID-19 vaccine that mimics the SARS-CoV-2 virus shape, eliciting both antibody and T cell responses. The vaccine, using polymersomes decorated with multiple copies of the receptor binding domain antigen, shows promise for longer-lasting immunity.
A new microneedle patch containing cerium nanoparticles has been designed to combat both primary causes of baldness: oxidative stress and insufficient circulation. The patch showed faster hair regrowth in a mouse model compared to a leading treatment.
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Researchers found changes in erythrocyte morphology and nanoparticles on cell surfaces during radiation therapy, which may indicate treatment effectiveness or prognosis. The study suggests that analyzing these changes could lead to the development of a diagnostic method for assessing RT efficacy.
Researchers at Hokkaido University created a lipid polymer that can carry genetic code into lung cells, potentially treating diseases such as acute respiratory distress syndrome and lung cancers. The delivery method bypasses the liver and targets specific lung cells without targeting ligands.
Researchers developed magnetic, biodegradable nanomaterials that reduced the likelihood of mice fathering pups for at least 30 days. The nanoparticles were non-toxic to cells and gradually eliminated from the body.
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Researchers create fluorescence-based nanoparticle tracking analysis system for characterizing size and protein expression of individual extracellular vesicles. The system enables analysis of specific proteins in EVs at individual particle levels, providing insights into various life processes.
Researchers at Hokkaido University have designed a highly stable platinum-gallium catalyst that can support propylene production at very high temperatures, making it suitable for a month. The 'doubly decorated' catalyst is alloyed with lead and calcium, which blocks side reactions and improves stability.
Researchers developed nanoparticles that absorb near-infrared light, creating heat and inhibiting electrical activity in neurons. The biocompatible and biodegradable nanoparticles offer a potential tool for controlling neuronal activity remotely.
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The study investigates the cellular uptake of Pr3+:LaF3 nanoparticles and their potential as cell nano-sensors. The results show that both nanoplates and nanospheres are easily internalized by A-549 cells via macropinocytosis, leading to an increase in optical inhomogeneity and potentially enabling temperature sensing.
Researchers developed nanoscale sensors that can convert brain electrical activity into optical signals detectable outside the body. These sensors, called NeuroSWARM3, offer a non-invasive way to track brain activity and could one day enable people with physical disabilities to interact with the world and control wearable technology.
Berkeley Lab's Partnership for Advanced Window Solutions accelerates nationwide adoption of highly efficient windows. Researchers also discover unique microbial signatures in cities worldwide and investigate oxygen loss in lithium-ion batteries.
LETI researchers identified the main properties of magnetotactic bacteria and described their application in medicine. They will help create theranostic agents in neurooncology and cardioprotection by using magnetosomes to transport drugs directly to malignant tumors.
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Researchers at Kyoto University have discovered a way to enhance radiation therapy using iodine nanoparticles, which trigger cancer cell death when exposed to X-rays. The study reveals that the optimal energy level for X-ray irradiation is 33.2 keV, causing double-strand breaks in DNA and leading to programmed cell death.
Researchers at UTA are developing a new diagnostic tool for small breast tumors, using nanoparticles and ultrasound to detect temperature differences in the body. The technique has the potential to reduce anxiety and costs associated with biopsy procedures, while also improving treatment outcomes.
Scientists investigate how bacteria develop resistance to silver nanoparticles, identifying a key genetic mutation and differences in motility. The findings suggest that silver nanoparticles may be effective against certain strains of bacteria, but caution is needed to prevent resistance.
A study by University of Copenhagen researchers reveals that nanoparticles can target venules, not capillaries, to deliver drugs to the brain. The breakthrough allows for more efficient and safer therapeutic approaches to treat neurodegenerative diseases like Alzheimer's and Parkinson's.
By briefly delocalizing particles over exponentially larger distances, researchers can harness the quantum nature of nanoparticles. This technique also enables highly sensitive instruments to determine forces such as gravity with high precision.
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Researchers at Osaka University found that silver nanoparticles induce crystallization in clathrate hydrates, a potential application for latent heat storage materials. The study may lead to improved efficiency in solar energy and heat recovery technologies.
A study by University of Illinois researchers has shown that small quantities of hydrocarbons can be produced when CO2 and water react in the presence of light and a silver nanoparticle catalyst. The findings demonstrate a viable technology for renewable energy generation and chemical manufacturing.
Scientists discover fumed silica nanoparticles as an anti-ageing binder to reduce moisture susceptibility and increase durability in warm mix asphalt. The findings offer a cost-effective solution to minimize asphalt-related emissions, paving the way for longer-lasting roadways.
Researchers at Duke University developed acoustoelectronic nanotweezers that control nanoparticles using sound-induced electric fields. This label-free, dynamically controllable method can be applied to various technologies, including biomedicine and condensed matter physics.
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A new engineering strategy introduces photo-controllable profragrance nanoparticles with flash nanoprecipitation technology, allowing for tunable particle size and precise control over fragrance release. This innovation enables the scale-up of profragrance fabrication and has potential for industrial applications.
Researchers at Texas A&M University used machine learning to evaluate metallic nanoparticles' susceptibility for plant uptake. The algorithm indicates how much plants accumulate nanoparticles in their roots and shoots, providing a safer approach to nanotechnology in agriculture.
Researchers developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where needed. The study showed complete treatment of inflammation in mice, at a drug concentration where standard delivery methods were ineffective.
Researchers have measured the super-slow process of oxygen loss in lithium-ion batteries, revealing how it changes the electrode's structure and chemistry over time. This new understanding could lead to the development of new ways to engineer electrodes and prevent oxygen loss-related degradation.