Articles tagged with Nanoparticles
Researchers developed a nanoparticle delivery system to stimulate blood vessel growth in the newborn lung, improving survival rates from 70% to 35%. The treatment involves delivering an engineered nanoparticle carrying a STAT3 gene vector, which prompts blood vessel growth and improves lung function.
Researchers have developed a platform that produces bespoke star-shaped polypeptide nanoparticles, effectively delivering range of therapies including gene therapies. The material accelerates bone tissue regeneration with a six-fold increase in new bone formation.
Mineral nanoparticles exhibit enzyme-like properties, catalyzing superoxide and H2O2 production, influencing microbial-mineral coevolution and nutrient cycling. Their discovery challenges traditional views on nanomaterials' inertness in Earth systems.
Divita Mathur is investigating cytosolic access and instability of DNA nanoparticles to overcome current delivery mechanisms. The goal is to create more biocompatible delivery systems, enabling advanced targeted therapies.
A new water filter membrane made from natural raw materials has been developed to render viruses harmless. The membrane combines protein nanofibrils with iron oxyhydroxide nanoparticles to eliminate a wide range of water-borne viruses, including those causing gastrointestinal infections, with great efficiency.
A team of researchers from KTH Royal Institute of Technology has developed a novel nanoparticle design that enhances the contrast of living tissues for X-ray fluorescence imaging. This breakthrough enables early stage tumor detection with lower doses of radiation.
Scientists create synthetic melanin-like nanoparticles to overcome limitations of current dopamine delivery methods, achieving efficient and controlled release in the brain. The proposed method demonstrates promising results in reversing Parkinson's symptoms with high biocompatibility and non-toxicity.
The NIH has launched a clinical trial for a novel influenza vaccine that offers long-lasting protection against multiple flu virus strains. The vaccine, known as FluMos-v1, is designed to stimulate antibodies against the HA protein using nanoparticle scaffolds.
Researchers at Kazan Federal University and Chinese Academy Sciences have developed peptide nanoparticles that can be visualized in living cells using hyperspectral microscopy. These nanoparticles have the ability to scatter light efficiently, allowing for non-fluorescent labeling of cells.
Researchers reviewed various nanofibrous membranes for their filtration efficiency and pressure drop, highlighting the trade-off between mechanical adsorption and electrostatic adsorption in nanoparticle removal. Six filter classifications were also presented, including net/nanofiber and conductive filters.
A team of researchers has developed a new method to combine perovskite nanocubes with spherical nanoparticles to form structured, multi-part nanocrystals. These materials display fundamental new properties such as superfluorescence, which can be harnessed for practical uses like ultrabright quantum light sources.
Scientists have developed a method to quantify internal OH- impurities in upconversion nanocrystals, revealing an exponential relation between luminescence intensity and OH- content. This discovery enriches our understanding of the quenching mechanism and paves the way for highly efficient lanthanide-doped materials.
The vaccine has the potential to improve seasonal flu vaccine effectiveness, produce vaccines faster and use smaller doses. It achieved a strong immune response in mice, providing protection against two different strains of influenza.
Research at TU Wien reveals that individual facets of nanoparticles can form oscillations of different frequencies when exposed to oxygen and hydrogen. This complex behavior can lead to more effective catalysts and insights into non-linear reaction kinetics.
Research by MSU's Morteza Mahmoudi suggests that Covid-19 vaccines developed with nanomedicine may have different efficacies for men and women due to sex-based differences. The study highlights the importance of considering sex in vaccine development and research, particularly in using nanomedicines.
Researchers have developed a novel nano-photosynthetic system using blue-green algae and nanoparticles to treat stroke patients. The approach reduces neuronal damage and improves motor function in mice with blocked cerebral arteries, showing promise for human clinical trials.
Sumit Sharma, assistant professor at Ohio University, has received a $511,902 NSF CAREER grant to investigate surfactant molecule adsorption on metallic nanoparticles. His research aims to develop a fundamental theory explaining the optimal surfactants for specific results.
The special issue explores the subtopics of in vivo fate of drug nanocarriers through review and research articles. Featured papers discuss intracellular uptake, impact of particle size and pH on protein corona formation, and in vivo dissolution of poorly water-soluble drugs.
Researchers at Scripps Research have unveiled an innovative Ebola virus vaccine design that stimulates a better protective immune response. The new approach involves tethering copies of the Ebola virus outer spike protein to a spherical carrier particle, resulting in a more stable and realistic-looking virus particle.
The review explores recent strategies in surface functionalization, their specific biomedical applications, and comparative toxicities with non-functionalized metallic nanoparticles. It discusses the challenges for metallic NPs to undergo human clinical trials due to their aggregation and toxic nature.
By vaporizing metals within a magnetic field, UC Riverside engineers direct the reassembly of metal atoms into consistent shapes and surfaces. The approach enables manipulation of particle assembly, producing string-like aggregates or globular clusters with tunable properties.
KAUST researchers have developed a robust catalyst that converts carbon dioxide into carbon monoxide gas with 100% selectivity, overcoming the limitations of precious metals. The innovative method uses MOFs to create mixed metal catalytic nanoparticles in a homogenous mixture.
Inkjet printing of metal nanoparticles forms layers with functional anisotropy, causing electrical conductivity to vary between horizontal and vertical directions. Researchers discover that organic chemical residues in the inks are responsible for this effect, enabling new techniques to overcome it.
The patented technology uses magnetic nanoparticles to capture lithium and other critical materials from brines, offering a more efficient and cost-effective process. This innovation has the potential to reduce energy consumption and create new domestic supply chains for these essential elements.
A new pan-coronavirus vaccine has proven effective in protecting monkeys and mice from various coronavirus infections, including SARS-CoV-2 and its variants. The vaccine triggers neutralizing antibodies via a nanoparticle and targets a cross-reactive site of vulnerability on the spike protein.
Researchers developed an uncrackable combination of invisible ink and artificial intelligence to encrypt messages securely. Using a carbon nanoparticle-based invisible ink and AI algorithms, they achieved 100% accurate decryption with UV light exposure.
Researchers at UTA are combining nanoparticles and light waves to treat traumatic brain injuries on the battlefield. The goal is to create a synergistic effect with improved healing outcomes.
A new strategy combines AIEgen-mediated photodynamic therapy with Poly(I:C)-based immunotherapy to enhance anti-tumor immune responses. The system induces tumor cell death and stimulates cytokine release, demonstrating potential for preventing tumor recurrence and metastasis.
Researchers develop Nanotraps that capture SARS-CoV-2 viruses within the body, utilizing the body's own immune system to destroy them. The therapy has shown promising results in early stages of testing and could potentially be administered via a nasal spray as a treatment for COVID-19.
Scientists developed zinc-modified aluminum oxide membranes for heavy metal removal, achieving high efficiency rates. The membranes showed antifouling properties and were reusable up to three cycles.
Researchers at Rice University reveal a two-step process by which silver ions are released from nanoparticles, with the possibility of stabilizing the alloy through gold manipulation. The discovery could lead to the development of new catalysts and materials for various applications.
Researchers develop nanoparticles that penetrate human cells and destroy bacteria, offering new hope against antibiotic resistance. The particles use cerium oxide to create reactive oxygen species that kill germs, reducing the likelihood of resistance development.
Researchers create nanostructured bimetallic catalysts with enhanced activity and stability, offering a cost-effective alternative to noble metal-based catalysts. The new material is stabilized on a conductive surface using a polymeric material, enabling predictable catalysis performance.
Scientists have developed a method to create crystalline exoskeletons around delicate liposomes and lipid nanoparticles, stabilizing them at room temperature for up to two months. This breakthrough could help address the need for COVID-19 vaccines to be kept at below-freezing temperatures during transport and storage.
Researchers used mirror SELFI to detect nanoparticles' size and location with nanometre resolution, enabling tracking of disease-causing viruses. This breakthrough could lead to new sensing methods for biomedical applications.
University of Central Florida researchers have developed a new screening technique using nickel-platinum nanoparticles to increase ELISA sensitivity for diseases like cancer, allowing for earlier diagnosis and potentially saving lives.
ITQB NOVA researchers have developed a new approach to produce hydrogen from light using non-photosynthetic microorganisms. The biohybrid systems combine high hydrogen-producing bacteria with self-produced cadmium sulfide nanoparticles, which capture light and enable direct energy transfer.
Researchers have developed next-generation influenza vaccines that protect against a wide variety of seasonal and pandemic strains, including avian viruses H5N1 and H7N9. These nanoparticle-based vaccines spur strong immune responses in animal trials, potentially lowering the risk of bad flu seasons.
Columbia Engineers use DNA nanotechnology to design nanoparticle-based 3D materials that can withstand extreme conditions. The new fabrication process results in robust and fully engineered nanoscale frameworks with a broad range of applications.
Researchers employed nanoparticles-based delivery systems to deliver AMPs for treating deep infections. Intelligent nanocarriers can achieve selective activation and target at infection sites, improving therapeutic efficacy against bacterial infections and reducing toxicity.
Researchers have developed a novel nanoparticle delivery system that enhances the effectiveness of neuroprotectant NA1 in treating stroke. The study found that nanoparticles carrying NA1 reduced stroke size by 69.8% and brain swelling by 60.3%, leading to improved survival rates.
Scientists have developed a new technique to manipulate nanoparticles with the same refractive properties as their background environment, overcoming a fundamental technical challenge. This breakthrough has huge potential in fields like medicine, enabling precise manipulation and measurement of microscopic objects inside cells.
Researchers successfully filmed and restored the 3D structure of nanoparticles that share structural similarities with viruses using X-ray free electron laser (XFEL) and machine learning. This breakthrough enables high accuracy and speed imaging of viruses, opening new avenues for understanding their structures.
Kytai Nguyen's research aims to reduce complications and improve quality of life for PAD patients by delivering plasmids that protect cells and promote new blood vessel growth. The project has the potential to offer hope to millions worldwide affected by this common malady.
Researchers at UC San Diego have created coronavirus-like nanoparticles to serve as positive controls for COVID-19 tests, ensuring reliability and accuracy. These new controls can be used with existing tests or adapted to newer assays, making them a valuable tool for mass testing in underserved areas.
Researchers have developed a new technique using bowl-shaped nanoparticles to study Alzheimer's disease amyloid beta protein aggregates. The findings confirm multiple forms of these aggregates co-exist and not all convert into brain plaques, opening possibilities for diagnostic and treatment applications.
A research team led by Berkeley Lab has captured high-resolution videos of nanoparticles forming solid-like layers at the interface between oil and water. The findings could help optimize liquid structures for advanced biomedical applications such as drug discovery and targeted cancer treatment.
A new virus detection method has been developed by KAUST researchers using magnetic nanoparticles, allowing for fast, safe and cheap testing of viruses in clinical and wastewater samples. The method rivals commercial viral-RNA extraction kits while lowering the risk of handling potentially infectious samples.
A new isolated lymphatic vessel lumen perfusion system was developed to evaluate the interaction between nanoparticles and lymphatic vessels. The system enables detailed examinations of nanomaterial movements and biological safety, paving the way for safe clinical applications.
Researchers developed a new strategy to destroy cancer cells using magnetic nanoparticles and constant magnetic fields. The combined effect of nanoparticles and magnetic fields reduced the viability of leukemia cells while sparing healthy cells, suggesting a selective therapeutic effect.
Scientists have developed a technology for obtaining magnetic nanoparticles using sweet flag extract, which exhibits antioxidant and antimicrobial properties. The new nanoparticles show antifungal activity against various species of fungi, demonstrating potential applications in agriculture and medicine.
Researchers uncovered dynamic details of a platinum-based catalyst's active site, resolving earlier conflicting reports. They found that only certain platinum atoms play an important role in the chemical conversion, which may lead to designing more efficient and cost-effective catalysts.
Scientists at NIST and University of Delaware developed a new method to create nanoparticle gels, which have potential uses in water filtration and smart windows. The resulting gel has a spongelike structure with interconnected microscopic channels, offering advantages for filtration and chemical reactions.
Researchers developed a next-generation nanotherapy that specifically targets injured regions of arteries in mouse models mimicking angioplasty. The nanoparticles containing an microRNA switch offer promising biotechnology to advance the fight against atherosclerotic cardiovascular disease.
A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors. Researchers found that the polymer-based nanoparticles activate STING even without a small molecule activator, causing a more sustained effect on the protein.
Scientists at Martin-Luther-University Halle-Wittenberg have fully determined the internal structure of single-chain nanoparticles (SCNPs) for the first time. The study reveals a 'nano-pocket' that protects dye or other molecules, enabling new imaging techniques and biomedical applications.
Researchers found that a previously overlooked phenomenon in chemical reactions can boost efficiency and reduce waste. The discovery, led by University of Illinois researcher David Flaherty, involves the formation of an organic residue that acts as a surface redox mediator, increasing reaction rates and hydrogen peroxide production.
Researchers found that silver nanoparticles in antimicrobial plastic can form in foods and beverages, especially in sweetened products. The study suggests that long-term storage of these packaged items could lead to the transfer of silver ions into food and drinks, potentially harming human health.
Researchers at Yale University have developed an injection treatment for skin cancer that uses polymer-based nanoparticles carrying chemotherapy agents. The treatment's bioadhesive properties allow it to kill cancer cells and stimulate the immune system, potentially eliminating the need for surgery.
Physicists have developed a new material for water desalination that can accelerate evaporation up to 2.5 times and detect hazardous substances. The material, made of titanium dioxide nanoparticles decorated with gold nanoclusters, absorbs light across the entire visible spectrum, converting it into heat.