Researchers have developed a unique combination of microscopy techniques to study the biological effects of nanoparticles and their interaction with human plasma. This approach allows for an unprecedented view of the nanoparticle's 'corona', also known as its biological 'crown', which contains clues about how nanoparticles interact wit...
Researchers at Ruhr-University Bochum have developed a method to control the direction of nerve fiber growth using magnetic nanoparticles. The team successfully implanted functionalized nanoparticles into model neurons, allowing them to guide axon growth and potentially promote regeneration in Parkinson's patients.
Researchers at Columbia University have developed the first nanomaterial that demonstrates photon avalanching, a process with extreme nonlinear optical behavior and efficiency. The realization of this phenomenon in nanoparticle form opens up new applications in sensing, imaging, and light detection.
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A new class of crystalline material called avalanching nanoparticles (ANPs) overcomes the diffraction limit without heavy computation or a super-resolution microscope. ANPs enable real-time high-resolution bioimaging of cells' organelles and proteins, as well as ultrasensitive optical sensors and neuromorphic computing.
Researchers developed nanoparticles displaying SARS-CoV-2 RBD with diverse bat and pangolin betacoronavirus RBDs, eliciting cross-reactive immune responses in mice. The approach showed promise as a candidate vaccine against COVID-19 and emerging coronaviruses
A new nanoparticle vaccine platform has been developed to protect against many strains of coronaviruses, including SARS-CoV-2. The vaccine, called a mosaic nanoparticle, presents the immune system with multiple different coronavirus variants at once, generating a diverse antibody response.
Researchers at NTU Singapore have developed oral insulin nanoparticles that can carry large amounts of insulin, making them a potential alternative to painful injections. The nanoparticles are stable and able to pass through the intestinal wall into the bloodstream, offering a promising solution for diabetic patients.
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Researchers at the University of Illinois Chicago developed a new catalyst made from 10 elements that can lower methane combustion temperatures by half. This could lead to a significant reduction in harmful greenhouse gases produced by burning natural gas in households, power turbines, and cars.
Researchers have developed a nanoparticle vaccine that elicits a virus-neutralizing antibody response in mice after just one dose. The spike/ferritin nanoparticles may be a viable strategy for single-dose vaccination against COVID-19, suggesting potential improvements over current two-dose regimens.
Researchers at Stanford University have created a nanoparticle vaccine candidate for COVID-19 that shows promise in inducing immunity after just one dose. The vaccine uses nanoparticles studded with the virus's surface spikes to trigger an immune response, offering a potential alternative to traditional viral-based vaccines.
Researchers from University of Illinois Chicago and Argonne National Laboratory developed alloy nanoparticles with high entropy, showing exceptional stability and durability during chemical reactions. These findings have potential applications in energy storage and conversion technologies, such as fuel cells and solar cells.
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A novel nanoparticle platform facilitates therapeutically effective delivery of encapsulated agents to the brain, opening possibilities for treating neurological disorders. The technology showed three times more accumulation in brain than conventional methods and was therapeutically effective in mouse models.
The authors review future directions of nanomedicine development focusing on the mechanism of nanoparticle entry into tumors. Designing better nanoparticles to achieve efficient clinical transformation can be informed by a deep understanding of the mechanism of nanoparticle entry or the mode of action.
Researchers developed a new microscopy method to visualize the building blocks of 'smart' materials being formed at the nanoscale. The technique, called VC-LCTEM, allows scientists to see the reaction taking place in real time, enabling them to understand how to speed up and control the process.
Researchers from Siberian Federal University found that nanoparticles can dramatically change rock wettability characteristics, leading to increased oil recovery. The study showed that even small amounts of nanoparticles added to the liquid improved oil production efficiency by weakening capillary forces and reducing interfacial tension.
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Researchers have developed nanoparticles that can breach cell barriers and kill tumor cells, reducing tumor sizes by 40-70% in mice. The highly selective toxicity of the particles offers new hope for treating aggressive cancers.
Researchers at Duke University have created a new method to concentrate and separate nanoparticles using sound waves, working in under a minute instead of traditional centrifugation methods which take hours or days. The technique can be used for precision bioassays, cancer diagnosis, and more.
Researchers from SUTD and MIT developed a procedure to link large-scale assembly processes to molecular simulations, allowing them to study the movement and interactions of atoms and molecules. They successfully simulated a large-scale virus, M13, with nanoparticles for fifty nanoseconds, overcoming previous limitations.
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Scientists create tiny Janus balls that change color under a magnetic field, potentially used in inks for anti-counterfeiting tags. The technology could help manufacturers stay one step ahead of sophisticated counterfeiters.
Researchers have developed a new technique to analyze the properties of individual cobalt oxide particles, enabling more efficient catalysts for hydrogen production. The method allows for the selection of particles under an electron microscope and their placement on a nanoelectrode for electrochemical analysis.
Researchers from RUDN University have synthesized new chitin-based antibiotics with enhanced antibacterial activity, outperforming existing compounds like ampicillin and gentamicin. The newly created substances also exhibit non-toxicity and potential as catalysts in organic synthesis.
Chemists from RUDN University synthesized biopolymers based on chitin from crab shells, forming effective catalysts for organic reactions. The new catalysts can be reused over ten times without reducing yield or damaging nanoparticles.
Optical tweezers have been extended to trap nanoscale particles by exploiting a particular property of light diffraction at the interface between a glass and a liquid. The device uses 'Arago spots' and 'total internal reflection' to confine particles in a donut-shaped wave, enabling precise manipulation without physical contact.
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KAIST researchers have synthesized nanoparticles that emit multiple wavelengths of light from a single particle, allowing for the control of these particles' properties and creation of environmentally responsible displays and lighting. The discovery also sheds new light on the mechanisms governing the optical properties of carbon dots.
A Penn State research team conducted field tests on three commonly used mineral-based aerosol sunscreens, finding trace nanoparticles but at safe levels. The study suggests that the canister design and active ingredients are unlikely to produce vastly different amounts of nanoparticles.
Researchers have demonstrated a way to control nanoparticles to lase at low power, producing sharp signals for biosensing and bio-imaging. This breakthrough reduces tissue damage and improves the accuracy of sensing indicators, holding promise for early-stage disease detection.
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Researchers at Harvard have developed an ionic forcefield coating that allows nanoparticles to bypass the immune system's first line of defense. In mouse experiments, coated nanoparticles survived longer in the body and reached their target location with increased efficiency.
Researchers developed an animal-free method to predict nanoparticle toxicity, enabling safer industrial materials production and reducing environmental risks. The new approach identifies key cellular events triggering inflammation, allowing for high-throughput testing and connectable with in silico modeling.
The study introduces a new generation of multifunctional materials created by adding carbon nanoparticles to polymer matrices, allowing for self-sensing properties. This technology has the potential to replace sensors in weight-critical systems and manufacture electrically conductive materials for various applications.
Scientists create technique to remotely manipulate heat sources and associated fluid flows using laser light. This enables new functionalities in optofluidics, such as selective delivery of nano-objects and analytes. The method also demonstrates programmable control over optical propulsion forces and fluid streams.
A Brazilian company developed a plastic film that eliminates 79.9% of SARS-CoV-2 particles in three minutes and 99.99% in up to 15 minutes, making it a promising material for food packaging protection against the novel coronavirus. The film contains silver and silica nanoparticles and has been successfully tested in laboratory settings.
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Researchers at Duke University have developed a simplified method to calculate the attractive forces between nanoparticles, allowing for faster simulations and potentially leading to breakthroughs in fields like solar energy and catalysis. The new approach has been shown to be accurate within 8% of the actual results.
A new optical imaging technology called PANORAMA has been developed to detect and study nanoscale objects as small as 25 nanometers in diameter. This technology uses unscattered light to monitor changes in transmission and determine the target's characteristics, making it possible to view nanoparticles directly without labeling.
The University of Connecticut has licensed its groundbreaking continuous manufacturing technology for pharmaceutical nanoparticles to DIANT Pharma Inc. This technology offers several advantages over conventional batch manufacturing approaches, including highly controlled particle size, high-throughput production, and a smaller footprin...
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Researchers have developed a novel method to synthesize sub-nanoparticles (SNPs) with controlled composition and size, enabling the discovery of unique properties. The team found unusual electronic states and oxygen content in SNPs with an indium-to-tin ratio of 3:4, leading to different optical properties.
Researchers demonstrate a solvent-assisted ligand exchange-hydrogen reduction strategy for selective encapsulation of ultrafine metal nanoparticles within the shallow layers of MOF. This approach reduces mass transfer resistance and enhances metal dispersion, promoting highly efficient hydrogenation reactions.
Researchers have developed nanoparticles that can cross the blood-brain barrier and be captured by neuronal cells, enabling direct drug delivery to the brain. This breakthrough finding holds promise for improved treatment of neurodegenerative diseases affecting millions of Canadians.
A new study has identified the coral skeleton growth mechanism, revealing that controlling water temperature is crucial for restoring reefs. The research suggests that corals regulate their internal ion concentrations by pumping calcium and carbonate ions from seawater through coral tissue.
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Researchers have developed a novel method to convert carbon dioxide to carbon monoxide at room temperature using localized surface plasmons. This process eliminates the need for high heat, reducing energy requirements and costs in industrial production.
A new ultrapotent COVID-19 vaccine candidate, designed via computer, has been shown to produce virus-neutralizing antibodies in mice at levels ten times greater than those seen in people who have recovered from COVID-19 infections. The vaccine candidate also elicited a strong B-cell response after immunization.
Researchers at University at Buffalo have discovered a method to convert a coronavirus protein into a nanoparticle, which could lead to more effective vaccines against COVID-19. High antibody levels were induced in laboratory mice and rabbits after immunization with the RBD particles.
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Researchers from China University of Petroleum have designed ultra-small hollow alloy nanoparticles that exhibit excellent electrocatalytic activity and stability for the hydrogen evolution reaction. The unique structure provides abundant active centers, reducing the cost of platinum-based electrocatalysts.
Researchers developed a plastic film containing silver-silica nanoparticles that inactivates the novel coronavirus on contact, reducing SARS-CoV-2 particles by almost 100%. The film is made by Brazilian company Nanox and has been approved as a PPE mask for COVID-19 protection.
Researchers have developed an ultra-sensitive hybrid nanothermometer that can detect small temperature changes in ambient conditions. The device uses a nitrogen-vacancy center in diamond and a magnetic nanoparticle to measure thermal signals with a precision of 76 microkelvin per second.
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Researchers developed tiny optically powered machines that self-assemble and can manipulate tiny cargo for applications like nanofluidics and particle sorting. The machines use circularly polarized light from a laser to create a nanoparticle array acting like a gear, influencing nearby particles to orbit the array.
University of Delaware researchers develop tiny cargo-carrying systems that can selectively bind to degrading collagen, providing site-specific medicine delivery over longer periods. These nanoparticle carriers have the potential to improve treatment for diseases like osteoarthritis and rheumatoid arthritis.
Researchers discovered markers of Alzheimer's, Parkinson's and motor neurone disease in the brains of young Mexico City residents exposed to dirty air, linked to particulate pollution. Tiny nanoparticles were also found, which can cause inflammation and oxidative stress.
Researchers discover a new method for making nanoparticles that can efficiently capture over 95% of proteins, DNA, or small molecule drugs. The process uses a self-assembling polymer to create a nanonet that collapses into nanogels, trapping therapeutics with high efficiency.
A new study reveals that nanoparticles can damage human cells when combined, even if individual types do not cause harm. Researchers call for more studies on the effects of lifelong exposure to nanoparticles, which are used in various products and manufacturing processes.
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Researchers used zebrafish embryos to visualize the interactions between nanoparticles and cells, revealing that protein coronas can make nanoparticles appear non-self to cells. This understanding could lead to improved targeted drug delivery systems.
Researchers from Peter the Great St. Petersburg Polytechnic University successfully created silver nanoparticles in an ion-exchanged glass using infrared nanosecond laser pulses. The nanoparticles demonstrate surface plasmon resonance, enabling signal enhancement of up to 10^6 times in Raman spectroscopy.
Researchers at TU Wien and DESY discovered a material that can be switched between two states: one is catalytically very active, the other less so. The switching is controlled by tiny iron nanoparticles on the surface, which change between metallic and oxidic states depending on the voltage applied.
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This study investigates the antimicrobial effect of rosemary and ginger essential oil-based nano-sized formulations on colistin-resistant K. pneumonia clinical isolates. The results show that oil-loaded chitosan nanoparticles exhibit high antimicrobial and antibiofilm activity, inhibiting the expression of the biofilm gene mrkD.
Scientists at Tokyo Institute of Technology create alloyed metal nanoparticles using the atom hybridization method, achieving superior catalytic activity and stability. The sub-nanoparticles (SNPs) exhibit high reactivity even under mild conditions, producing unique compounds and hydroperoxides.
Researchers at Ohio State University have discovered that RNA nanoparticles exhibit elastic and rubbery properties, enabling them to target tumors by slipping through tumor blood vessels. The particles are also excreted from the body quickly via urine, reducing toxicity.
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Scientists at Argonne National Laboratory developed a new nanocatalyst that uses gold to eliminate platinum dissolution, increasing fuel cell durability. The discovery is a breakthrough for PEMFC-powered transportation, offering a solution to the current performance limitations.
Researchers developed a non-toxic nanofluid using commercially available sodium, achieving 80% oil recovery in lab tests. The nanofluid works through multiple mechanisms, including generating heat and reducing viscosity, making it a game-changing technology for oil recovery.
Researchers are co-developing a new, rapid-acting, long-lasting disinfectant spray that instantly kills viruses without harsh chemicals. The spray uses UCF-developed cerium oxide nanoparticles, which have shown therapeutic properties against various diseases.
Researchers at Skoltech have developed a simple and efficient method to convert silicon wafers into nanoparticles in an aqueous solution, providing a new source of sustainable materials. The process enables controlling particle sizes and has implications for optics, photonics, medicine, and other fields.
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A researcher has received a five-year, $1.8 million grant to develop and improve oral drug delivery systems for poorly water-soluble molecules. The goal is to increase the effectiveness of these drugs, which currently have limited technology options.