Articles tagged with Nanoparticles
Researchers have developed a novel nanoparticle delivery system that enhances the effectiveness of neuroprotectant NA1 in treating stroke. The study found that nanoparticles carrying NA1 reduced stroke size by 69.8% and brain swelling by 60.3%, leading to improved survival rates.
Scientists have developed a new technique to manipulate nanoparticles with the same refractive properties as their background environment, overcoming a fundamental technical challenge. This breakthrough has huge potential in fields like medicine, enabling precise manipulation and measurement of microscopic objects inside cells.
Kytai Nguyen's research aims to reduce complications and improve quality of life for PAD patients by delivering plasmids that protect cells and promote new blood vessel growth. The project has the potential to offer hope to millions worldwide affected by this common malady.
Researchers successfully filmed and restored the 3D structure of nanoparticles that share structural similarities with viruses using X-ray free electron laser (XFEL) and machine learning. This breakthrough enables high accuracy and speed imaging of viruses, opening new avenues for understanding their structures.
Researchers at UC San Diego have created coronavirus-like nanoparticles to serve as positive controls for COVID-19 tests, ensuring reliability and accuracy. These new controls can be used with existing tests or adapted to newer assays, making them a valuable tool for mass testing in underserved areas.
Researchers have developed a new technique using bowl-shaped nanoparticles to study Alzheimer's disease amyloid beta protein aggregates. The findings confirm multiple forms of these aggregates co-exist and not all convert into brain plaques, opening possibilities for diagnostic and treatment applications.
A new virus detection method has been developed by KAUST researchers using magnetic nanoparticles, allowing for fast, safe and cheap testing of viruses in clinical and wastewater samples. The method rivals commercial viral-RNA extraction kits while lowering the risk of handling potentially infectious samples.
A research team led by Berkeley Lab has captured high-resolution videos of nanoparticles forming solid-like layers at the interface between oil and water. The findings could help optimize liquid structures for advanced biomedical applications such as drug discovery and targeted cancer treatment.
A new isolated lymphatic vessel lumen perfusion system was developed to evaluate the interaction between nanoparticles and lymphatic vessels. The system enables detailed examinations of nanomaterial movements and biological safety, paving the way for safe clinical applications.
Researchers developed a new strategy to destroy cancer cells using magnetic nanoparticles and constant magnetic fields. The combined effect of nanoparticles and magnetic fields reduced the viability of leukemia cells while sparing healthy cells, suggesting a selective therapeutic effect.
Researchers developed a next-generation nanotherapy that specifically targets injured regions of arteries in mouse models mimicking angioplasty. The nanoparticles containing an microRNA switch offer promising biotechnology to advance the fight against atherosclerotic cardiovascular disease.
Scientists have developed a technology for obtaining magnetic nanoparticles using sweet flag extract, which exhibits antioxidant and antimicrobial properties. The new nanoparticles show antifungal activity against various species of fungi, demonstrating potential applications in agriculture and medicine.
Researchers uncovered dynamic details of a platinum-based catalyst's active site, resolving earlier conflicting reports. They found that only certain platinum atoms play an important role in the chemical conversion, which may lead to designing more efficient and cost-effective catalysts.
Scientists at NIST and University of Delaware developed a new method to create nanoparticle gels, which have potential uses in water filtration and smart windows. The resulting gel has a spongelike structure with interconnected microscopic channels, offering advantages for filtration and chemical reactions.
Scientists at Martin-Luther-University Halle-Wittenberg have fully determined the internal structure of single-chain nanoparticles (SCNPs) for the first time. The study reveals a 'nano-pocket' that protects dye or other molecules, enabling new imaging techniques and biomedical applications.
A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors. Researchers found that the polymer-based nanoparticles activate STING even without a small molecule activator, causing a more sustained effect on the protein.
Researchers found that a previously overlooked phenomenon in chemical reactions can boost efficiency and reduce waste. The discovery, led by University of Illinois researcher David Flaherty, involves the formation of an organic residue that acts as a surface redox mediator, increasing reaction rates and hydrogen peroxide production.
Researchers found that silver nanoparticles in antimicrobial plastic can form in foods and beverages, especially in sweetened products. The study suggests that long-term storage of these packaged items could lead to the transfer of silver ions into food and drinks, potentially harming human health.
Researchers at Yale University have developed an injection treatment for skin cancer that uses polymer-based nanoparticles carrying chemotherapy agents. The treatment's bioadhesive properties allow it to kill cancer cells and stimulate the immune system, potentially eliminating the need for surgery.
Physicists have developed a new material for water desalination that can accelerate evaporation up to 2.5 times and detect hazardous substances. The material, made of titanium dioxide nanoparticles decorated with gold nanoclusters, absorbs light across the entire visible spectrum, converting it into heat.
Researchers have developed a unique combination of microscopy techniques to study the biological effects of nanoparticles and their interaction with human plasma. This approach allows for an unprecedented view of the nanoparticle's 'corona', also known as its biological 'crown', which contains clues about how nanoparticles interact wit...
Researchers at Ruhr-University Bochum have developed a method to control the direction of nerve fiber growth using magnetic nanoparticles. The team successfully implanted functionalized nanoparticles into model neurons, allowing them to guide axon growth and potentially promote regeneration in Parkinson's patients.
Researchers at Columbia University have developed the first nanomaterial that demonstrates photon avalanching, a process with extreme nonlinear optical behavior and efficiency. The realization of this phenomenon in nanoparticle form opens up new applications in sensing, imaging, and light detection.
A new class of crystalline material called avalanching nanoparticles (ANPs) overcomes the diffraction limit without heavy computation or a super-resolution microscope. ANPs enable real-time high-resolution bioimaging of cells' organelles and proteins, as well as ultrasensitive optical sensors and neuromorphic computing.
A new nanoparticle vaccine platform has been developed to protect against many strains of coronaviruses, including SARS-CoV-2. The vaccine, called a mosaic nanoparticle, presents the immune system with multiple different coronavirus variants at once, generating a diverse antibody response.
Researchers developed nanoparticles displaying SARS-CoV-2 RBD with diverse bat and pangolin betacoronavirus RBDs, eliciting cross-reactive immune responses in mice. The approach showed promise as a candidate vaccine against COVID-19 and emerging coronaviruses
Researchers at the University of Illinois Chicago developed a new catalyst made from 10 elements that can lower methane combustion temperatures by half. This could lead to a significant reduction in harmful greenhouse gases produced by burning natural gas in households, power turbines, and cars.
Researchers at NTU Singapore have developed oral insulin nanoparticles that can carry large amounts of insulin, making them a potential alternative to painful injections. The nanoparticles are stable and able to pass through the intestinal wall into the bloodstream, offering a promising solution for diabetic patients.
Researchers have developed a nanoparticle vaccine that elicits a virus-neutralizing antibody response in mice after just one dose. The spike/ferritin nanoparticles may be a viable strategy for single-dose vaccination against COVID-19, suggesting potential improvements over current two-dose regimens.
Researchers at Stanford University have created a nanoparticle vaccine candidate for COVID-19 that shows promise in inducing immunity after just one dose. The vaccine uses nanoparticles studded with the virus's surface spikes to trigger an immune response, offering a potential alternative to traditional viral-based vaccines.
Researchers from University of Illinois Chicago and Argonne National Laboratory developed alloy nanoparticles with high entropy, showing exceptional stability and durability during chemical reactions. These findings have potential applications in energy storage and conversion technologies, such as fuel cells and solar cells.
A novel nanoparticle platform facilitates therapeutically effective delivery of encapsulated agents to the brain, opening possibilities for treating neurological disorders. The technology showed three times more accumulation in brain than conventional methods and was therapeutically effective in mouse models.
The authors review future directions of nanomedicine development focusing on the mechanism of nanoparticle entry into tumors. Designing better nanoparticles to achieve efficient clinical transformation can be informed by a deep understanding of the mechanism of nanoparticle entry or the mode of action.
Researchers developed a new microscopy method to visualize the building blocks of 'smart' materials being formed at the nanoscale. The technique, called VC-LCTEM, allows scientists to see the reaction taking place in real time, enabling them to understand how to speed up and control the process.
Researchers from Siberian Federal University found that nanoparticles can dramatically change rock wettability characteristics, leading to increased oil recovery. The study showed that even small amounts of nanoparticles added to the liquid improved oil production efficiency by weakening capillary forces and reducing interfacial tension.
Researchers at Duke University have created a new method to concentrate and separate nanoparticles using sound waves, working in under a minute instead of traditional centrifugation methods which take hours or days. The technique can be used for precision bioassays, cancer diagnosis, and more.
Researchers have developed nanoparticles that can breach cell barriers and kill tumor cells, reducing tumor sizes by 40-70% in mice. The highly selective toxicity of the particles offers new hope for treating aggressive cancers.
Scientists create tiny Janus balls that change color under a magnetic field, potentially used in inks for anti-counterfeiting tags. The technology could help manufacturers stay one step ahead of sophisticated counterfeiters.
Researchers from SUTD and MIT developed a procedure to link large-scale assembly processes to molecular simulations, allowing them to study the movement and interactions of atoms and molecules. They successfully simulated a large-scale virus, M13, with nanoparticles for fifty nanoseconds, overcoming previous limitations.
Researchers have developed a new technique to analyze the properties of individual cobalt oxide particles, enabling more efficient catalysts for hydrogen production. The method allows for the selection of particles under an electron microscope and their placement on a nanoelectrode for electrochemical analysis.
Chemists from RUDN University synthesized biopolymers based on chitin from crab shells, forming effective catalysts for organic reactions. The new catalysts can be reused over ten times without reducing yield or damaging nanoparticles.
Researchers from RUDN University have synthesized new chitin-based antibiotics with enhanced antibacterial activity, outperforming existing compounds like ampicillin and gentamicin. The newly created substances also exhibit non-toxicity and potential as catalysts in organic synthesis.
Optical tweezers have been extended to trap nanoscale particles by exploiting a particular property of light diffraction at the interface between a glass and a liquid. The device uses 'Arago spots' and 'total internal reflection' to confine particles in a donut-shaped wave, enabling precise manipulation without physical contact.
KAIST researchers have synthesized nanoparticles that emit multiple wavelengths of light from a single particle, allowing for the control of these particles' properties and creation of environmentally responsible displays and lighting. The discovery also sheds new light on the mechanisms governing the optical properties of carbon dots.
A Penn State research team conducted field tests on three commonly used mineral-based aerosol sunscreens, finding trace nanoparticles but at safe levels. The study suggests that the canister design and active ingredients are unlikely to produce vastly different amounts of nanoparticles.
Researchers have demonstrated a way to control nanoparticles to lase at low power, producing sharp signals for biosensing and bio-imaging. This breakthrough reduces tissue damage and improves the accuracy of sensing indicators, holding promise for early-stage disease detection.
Researchers at Harvard have developed an ionic forcefield coating that allows nanoparticles to bypass the immune system's first line of defense. In mouse experiments, coated nanoparticles survived longer in the body and reached their target location with increased efficiency.
Researchers developed an animal-free method to predict nanoparticle toxicity, enabling safer industrial materials production and reducing environmental risks. The new approach identifies key cellular events triggering inflammation, allowing for high-throughput testing and connectable with in silico modeling.
The study introduces a new generation of multifunctional materials created by adding carbon nanoparticles to polymer matrices, allowing for self-sensing properties. This technology has the potential to replace sensors in weight-critical systems and manufacture electrically conductive materials for various applications.
Scientists create technique to remotely manipulate heat sources and associated fluid flows using laser light. This enables new functionalities in optofluidics, such as selective delivery of nano-objects and analytes. The method also demonstrates programmable control over optical propulsion forces and fluid streams.
Researchers at Duke University have developed a simplified method to calculate the attractive forces between nanoparticles, allowing for faster simulations and potentially leading to breakthroughs in fields like solar energy and catalysis. The new approach has been shown to be accurate within 8% of the actual results.
A Brazilian company developed a plastic film that eliminates 79.9% of SARS-CoV-2 particles in three minutes and 99.99% in up to 15 minutes, making it a promising material for food packaging protection against the novel coronavirus. The film contains silver and silica nanoparticles and has been successfully tested in laboratory settings.
A new optical imaging technology called PANORAMA has been developed to detect and study nanoscale objects as small as 25 nanometers in diameter. This technology uses unscattered light to monitor changes in transmission and determine the target's characteristics, making it possible to view nanoparticles directly without labeling.
Researchers have developed a novel method to synthesize sub-nanoparticles (SNPs) with controlled composition and size, enabling the discovery of unique properties. The team found unusual electronic states and oxygen content in SNPs with an indium-to-tin ratio of 3:4, leading to different optical properties.
The University of Connecticut has licensed its groundbreaking continuous manufacturing technology for pharmaceutical nanoparticles to DIANT Pharma Inc. This technology offers several advantages over conventional batch manufacturing approaches, including highly controlled particle size, high-throughput production, and a smaller footprin...
Researchers demonstrate a solvent-assisted ligand exchange-hydrogen reduction strategy for selective encapsulation of ultrafine metal nanoparticles within the shallow layers of MOF. This approach reduces mass transfer resistance and enhances metal dispersion, promoting highly efficient hydrogenation reactions.
A new study has identified the coral skeleton growth mechanism, revealing that controlling water temperature is crucial for restoring reefs. The research suggests that corals regulate their internal ion concentrations by pumping calcium and carbonate ions from seawater through coral tissue.
Researchers have developed nanoparticles that can cross the blood-brain barrier and be captured by neuronal cells, enabling direct drug delivery to the brain. This breakthrough finding holds promise for improved treatment of neurodegenerative diseases affecting millions of Canadians.
A new ultrapotent COVID-19 vaccine candidate, designed via computer, has been shown to produce virus-neutralizing antibodies in mice at levels ten times greater than those seen in people who have recovered from COVID-19 infections. The vaccine candidate also elicited a strong B-cell response after immunization.
Researchers have developed a novel method to convert carbon dioxide to carbon monoxide at room temperature using localized surface plasmons. This process eliminates the need for high heat, reducing energy requirements and costs in industrial production.