Articles tagged with Nanoparticles
Researchers have created ultra-uniform nanodiamonds using a new chemical process that mimics the conditions found in natural diamond formation. The tiny crystals are crucial for drug delivery, sensors, and quantum computer processors. With this breakthrough, scientists can now control single atoms within larger structures.
Researchers at the University of Illinois created quantum dots to visualize macrophages in fat tissue, shedding light on chronic inflammation's role in diseases. The new technology enables accurate cell counting and tracking over time, offering a potential diagnostic tool for insulin resistance and metabolic syndrome.
Researchers have created a new type of colon tattoo ink that is more biocompatible and less prone to diffusion than existing inks. The ink uses metal-derived nanoparticles and polymers to adhere to the submucosal surface in the colon, allowing for better identification and removal of complex polyps and tumors.
Engineer Thomas Senftle at Rice University has won a prestigious NSF CAREER Award to improve catalysts through machine learning. He will develop open-source models to speed up the development of catalysts with optimized particle/support combinations, aiming to reduce unwanted molecules in water.
Scientists develop first system allowing two unrelated organisms to communicate via chemical signals, with potential applications in disease treatment and cell behavior modification. The nano-translator uses silica nanoparticles to react with glucose and phleomycin, enabling bacteria and yeast to exchange messages.
Researchers review current status of nanoparticle-enhanced photothermal therapy and photodynamic therapy, combining the two techniques to achieve highest treatment efficiency. Nanoparticles can deliver drugs or antibiotics to inaccessible sites, creating a more powerful treatment method.
Physicists simulate acoustic propulsion of freely orientable nanoparticles by traveling ultrasound waves, finding that particle orientation affects propulsion. The study reveals important properties of acoustically propelled nanoparticles suitable for biomedical applications.
Researchers at Massachusetts General Hospital found that using nanomedicines at lower, more frequent doses can normalize the tumor microenvironment and improve cancer treatments. The study showed that this approach can help correct abnormalities that protect tumors and improve blood vessel function and immune activation within a tumor.
A biodegradable nanoparticle has shown promise in reducing skin and lung scarring in mice with scleroderma. The treatment targets specific immune cells responsible for the disease's chronic inflammation and scarring.
Scientists have created a supramolecular template using dendron-assembled structures to synthesize quasi-sub-nanoparticles with controlled atomicity. This approach offers a cost-effective and versatile method for producing a variety of nanostructures.
Scientists have created a 'greener' way to clean wastewater treatment filters by using glucose-based nanoparticles, which effectively remove contaminants without destroying the membrane. The new system is more cost-effective and environmentally friendly than traditional methods.
Researchers from Osaka University report a new technique for tracking the synthesis of core–shell bimetallic nanoparticles in real time, allowing for fine-tuning of nanomaterial preparation. The technique uses a piezoelectric resonator to monitor particle shape changes and track interdiffusion of metals.
Scientists have developed a simple methodology for synthesizing novel β-SiC nanoparticle-based anode materials for lithium-ion batteries. These materials exhibit high current density, rated capacity and promising compatibility for reversible lithium-ion storage.
Researchers at RIKEN CSRS have developed a non-transgenic method to modify plant genes using a bioactive molecule spray, which can be used to improve crop yield and resistance to pests. The technique has shown promising results in improving economically desirable quality traits in crops.
Scientists at Japan Advanced Institute of Science and Technology have created nanoengineered bacteria for photothermal cancer immunotheranostics. The synthesized nanoparticles showed powerful photothermal conversion, high biocompatibility, and excellent tumor selectivity, facilitating clear fluorescent tumor visualization.
Researchers at UCSC developed a simple method to make aluminum nanoparticles that split water and generate hydrogen gas rapidly. The gallium-aluminum composite creates aluminum nanoparticles that react with water at room temperature, yielding large amounts of hydrogen.
Researchers at MIT have performed a systematic study on how different-sized polymer nanoparticles circulate in the body and interact with platelets to stop bleeding. They found that intermediate-sized particles (150 nanometers) were the most effective, with less likelihood of accumulating in off-target sites.
Rice University's Gang Bao receives $1 million CPRIT grant to develop a three-pronged strategy combining magnetic nanoparticles, free radical generation, and immune checkpoint blockade to kill cancer cells. The approach aims to increase the efficacy of cancer therapy, potentially leading to a clinical trial.
Scientists at Tufts University create nanoparticles that carry genetic instructions to specifically target the lungs, reducing tumors in a preclinical model of a rare genetic lung disease. The breakthrough could lead to improved treatment options for patients with lymphangioleiomyomatosis.
Researchers at Tokyo University of Science have developed bionanoparticles derived from corn that selectively target and inhibit the growth of cancer cells, inducing tumor necrosis factor-α release. These findings suggest a novel, economical, and safe anti-cancer therapy approach.
Researchers have developed a new system called Species Agnostic Nanoparticle Delivery Screening (SANDS) that improves the screening process for drug-delivering nanoparticles. SANDS allows for simultaneous testing of nanoparticles in mouse, primate, and human cells, enabling more accurate predictions of delivery in humans.
A team of researchers has reprogrammed the tumor microenvironment of liver cancer by using mRNA nanoparticles, restoring the function of the p53 master regulator gene. The approach increased antitumor immune responses in hepatocellular carcinoma laboratory models and shows promise for treating HCC and other cancers.
Researchers found nanoparticles from human activities rapidly grow in atmosphere and influence cloud formation, affecting raindrop formation and changing rainfall regime. The study provides new insights into the impact of small aerosols on precipitation and improves climate change studies based on mathematical models.
A study published in Nature Communications reveals that Schwann cells in the peripheral nervous system generate pain signals during migraines. Blocking these signaling pathways using nanoparticles offers promise for novel migraine treatments.
Researchers have designed a nanoparticle system that can deliver fluorescent dyes to diagnose and treat pancreatic cancer tumors. The system overcomes the challenge of reaching cells deep within dense tumor masses, enabling detailed images of tumor structures and potentially targeted therapies.
Researchers have identified the impact of protein corona formation on nanoparticles' physiochemical and biological properties. This knowledge can be used to optimize carriers for nanomedical applications, improving the efficiency and effectiveness of biopharmaceutical delivery.
The novel vaccine combines immune focusing and self-assembling nanoparticles to elicit a strong protective response. In animal studies, it showed higher levels of neutralizing antibodies than existing vaccines and protected mice from death in lethal challenge experiments.
Scientists at UC Riverside and UCLA have engineered nanoparticles to serve as 'molecular traps' that bind to SARS-CoV-2, preventing it from attacking macrophages and inducing inflammation. The findings suggest potential therapeutic strategies for treating COVID-19-associated diseases.
A new intranasal flu vaccine constructed with nanoparticles has been shown to offer strong protection against different influenza virus strains in mice. The vaccine elicited multifaceted immune responses, leading to robust cross-protection and long-lasting defense.
Researchers have developed a novel combination of two drugs delivered in nanoparticles that extend the survival of mice with medulloblastoma. The treatment targets the mTOR pathway and reduces off-target toxicity, making it a potential less toxic alternative to current treatments.
Researchers detected 43 trillion miniature plastic particles in Switzerland every year, with estimates suggesting up to 3,000 tonnes of nanoplastics covering the country annually. The study reveals that nanoplastics originate primarily from urban areas and global emissions, posing potential health risks when inhaled.
Janus particles, with two distinct physical chemical properties, exhibit unique behavior in simulations. Their shape significantly influences their orientation at interfaces and mobility, impacting rheology and processing schemes.
Researchers at TTUHSC developed novel hydrophilic nanoparticles that target bacterial membranes, killing pathogens while sparing mammalian cells. The nanoantibiotics' size-dependent activity reveals a new blueprint for developing non-toxic and environmentally friendly antibiotics.
Researchers have created a new, simpler way to fabricate SERS nanostructures with superior stability and performance at low cost. By using a heat-resistant polymer called polyimide (PI), they can produce nanosurfaces with nanopillars that enhance signal intensity for efficient chemical detection. The new fabrication method has the pote...
Researchers developed a novel polymeric nanoparticle that selectively binds to fibrinogen in human plasma, offering a simpler and less expensive way to manufacture fibrinogen concentrate. This breakthrough could lead to the creation of more efficient fibrinogen-specific affinity reagents for drug development.
Researchers at Penn Medicine have discovered a new method to prevent the body's proteins from attacking treatment-carrying nanoparticles, allowing for more effective delivery of therapies. By coating nanoparticles with natural suppressors of complement activation, such as Factor I, the team has shown improved protection against immune ...
Scientists develop hairy cellulose nanocrystals to capture and remove excess chemotherapy drugs from the blood. The nanocrystals effectively removed over 6,000 milligrams of doxorubicin per gram, increasing DOX capture by two to three orders of magnitude compared to existing methods.
Researchers at Japan Advanced Institute of Science and Technology develop a novel strategy to quickly separate intact lysosomes with high purity using magnetic-plasmonic hybrid nanoparticles. The technique allows for rapid extraction of lysosomes from cells, reducing the time required compared to existing methods.
Researchers developed a color-coded test that quickly signals whether medical nanoparticles deliver their cargo into target cells. The tool, tested in mouse cells and living mice, assesses nanoparticle formulations on their ability to escape cellular defenses and reach the cell's interior.
Researchers developed a method to enhance the conductivity of metal nanowire electrodes by using plasmon-enhanced laser nanosoldering. The technique involves irradiating silver nanoparticles with a high-intensity laser, creating hot spots that increase the contact area between particles and improve conductivity.
Researchers at Penn Medicine have developed a structural blueprint for nanoparticles that can target and deliver treatment to white blood cells, such as neutrophils, that contribute to acute lung inflammation. The findings represent a significant step in understanding the condition and function of the immune system.
Researchers have created nanoparticles that can store hydrogen, reducing the need for pressurized tanks and cooling. The discovery could enable climate-friendly fuels and production methods for airplanes, ships, and steel.
The discovery of electroferrofluids with nonequilibrium voltage-controlled magnetism has the potential to control pattern formation and structures, providing valuable insights into dissipative systems. This system can be used to study transition into dissipative systems and understand how external influences interact with the system.
Scientists at Japan Advanced Institute of Science and Technology developed a novel method to create liquid metal nanoparticles using biomolecules and quantum beam radiation. The resulting nanoparticles exhibited unique structural and physicochemical traits, enabling NIR bioimaging and photothermal activation for cancer treatment.
The project aims to decorate DNA sequences with colourful nano-lights to enable faster read/write processes and novel data encoding concepts. By using unique recognition capabilities of single DNA strands, the consortium plans to develop novel nanomaterials, algorithms, and reader devices for efficient data storage.
Researchers at NIST developed new standards and calibrations for optical microscopes, enabling accurate measurement of microdroplet volumes smaller than 100 trillionths of a liter. They combined microscopy with gravimetry to verify results, linking their findings to fundamental constants of nature.
Researchers have discovered a nanoparticle therapeutic that enhances cancer immunotherapy and treats malignant pleural effusion. The treatment targets the immune system to recognize and eliminate cancer cells, improving survival rates and quality of life for patients.
Recent preclinical study results demonstrate the Spike Ferritin Nanoparticle (SpFN) COVID-19 vaccine developed by WRAIR elicits potent immune responses and offers broad protection against SARS-CoV-2 variants and other coronaviruses. The SpFN vaccine uses a ferritin platform to present multiple copies of the coronavirus spike protein, i...
Researchers developed nanoparticles that activate key cancer fighters by driving up immunity at the tumor site, improving interactions with antibody therapies. The technique left six of 10 mice with lymphoma tumor-free and was effective in melanoma when combined with existing immune response amplifiers.
Researchers at Vanderbilt University Medical Center have identified a nanoparticle called a supermere, which carries enzymes, proteins, and RNA associated with multiple diseases. The discovery provides new insights into the role of extracellular vesicles and nanoparticles in disease transmission.
Scientists have created a new material using nanometer-scale ceramic particles decorated with polymer strands that exhibit enhanced toughness. The material's unique property allows it to dissipate energy from impacts rapidly, making it suitable for applications such as body armor and bulletproof glass.
Researchers have developed smart transformable nanoparticles that can alter their size and shape in response to physiological conditions, improving particle circulation, biodistribution, and targeted therapy for cancer theranostics. These particles promise enhanced tumor diagnoses and treatment by adapting to the physiology of tumors.
Researchers have designed a new nanoparticle adjuvant that significantly improves antibody production following vaccination against HIV, diphtheria, and influenza. The adjuvant speeds up lymph flow to lymph nodes, helps antigens reach B cells before breaking down, and activates inflammatory cytokines for a stronger response.
Scientists at UC San Diego create nanoparticles that mimic the flu virus's ability to escape endosomes, enabling efficient delivery of mRNA into cells. This breakthrough could lead to improved delivery of mRNA vaccines and therapies.
A simple change in the way donor cells are processed can maximize a single cell's production of extracellular vesicles, which are small nanoparticles naturally secreted by cells. The finding offers new avenues for research around cellular therapies, where transplanted cells are used to help the body heal or work better.
Researchers developed a nickel-cobalt metal dimer on nitrogen-doped carbon that can catalyze electrolysis under both acidic and basic conditions. The new system exhibits comparable overvoltage to commercial Pt-based catalysts and shows significant activity enhancements compared to individual single-atom catalysts.
Scientists at the University of Southampton have created nanoparticles that can target and kill deadly bacteria hiding in human cells. The breakthrough could lead to a new treatment method using injectable or inhalation-based antibiotic-laden capsules, potentially saving thousands of lives annually.
Researchers developed a new membrane-based separation technology using MOF nanoparticles, which consumes up to 90% less energy than traditional methods. The technology overcomes interfacial adhesion problems by fabricating compatible MOF fillers, improving membrane performance.
A new imaging technique called single-shot photoluminescence lifetime imaging thermometry (SPLIT) measures temperature in 2D, without contact, and in real-time. This technology could improve photothermal therapy and help detect skin cancers.
Researchers at St. Petersburg State University develop a new method for synthesizing nanoparticles from metal-organic frameworks, enabling detection of heavy metal ions in water with significantly lower limits of detection. The synthesized particles can also be used as luminescent sensors to detect Cu2+, Cr3+, and Fe3+ ions.