The study investigates the atomic flow behavior during joint formation, exploring processing time, temperature, and stress distribution on nanojoints. The results reveal that local stress and capillary interactions significantly impact joint quality, leading to advances in industrial applications of Ag nanowire interconnect networks.
Corneal graft rejection can be as high as 10% due to poor patient compliance with medications, which require frequent eyedrop administrations. Researchers at Virginia Commonwealth University developed nanoparticles to encapsulate eye medication, decreasing graft rejection while requiring fewer and smaller doses. The approach reversed s...
Georgia Institute of Technology researchers have developed a new treatment for lymphedema using nanoparticles that can repair lymphatic vessel pumping. The approach delivers a drug to help lymphatic vessels pump, targeting the problem rather than regrowing new vessels.
A team of researchers developed a novel cancer therapeutic combining antibody fragments with molecularly engineered nanoparticles, permanently eradicating gastric cancer in treated mice. The 'hit and run' drug delivery system targets HER2 proteins associated with gastric cancer.
A team of researchers has discovered a simple way to deliver cancer therapeutics to tumor cells by fluidizing the cell membrane using lipid nanoparticles containing EDTA. The mechanism is independent of metal chelation properties and involves changing the characteristics of the cell membrane to promote nanoparticle uptake.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateMar 16, 2023
A team of researchers at KAUST has developed a biological method to produce size-controlled palladium nanoclusters anchored on the surface of Geobacter sulfurreducens, outperforming benchmark catalysts in water-splitting reactions. This eco-friendly approach could provide a sustainable solution for high-performance catalysis.
Researchers from Swansea University and Université Grenoble Alpes demonstrate the effectiveness of selenium nanoparticles in killing ovarian cancer cell models. The study reveals a novel biological mechanism underlying the anti-cancer effect, involving histone methylatransferases and epigenetic processes.
Researchers from ETH Zurich have achieved groundbreaking cooling of a glass nanoparticle along two directions of motion, overcoming the 'Dark Mode Effect'. This breakthrough enables the creation of fragile quantum states and paves the way for ultrasensitive gyroscopes and sensors.
A new approach using nanoparticles has been shown to transport drugs across the blood-brain barrier in mice with medulloblastoma. The nanoparticles target a protein called P-selectin, which binds naturally to cancer cells, and trigger transcytosis to deliver drugs to brain tissue.
Gene therapy using CRISPR-Cas9 lipid nanoparticles has been shown to be highly effective in reducing target protein expression in mice. The new delivery system increases the efficiency of in vivo gene therapy, paving the way for safe and effective treatment.
Scientists at Universitat Autonoma de Barcelona have created spherical nanoparticles inspired by amyloid proteins that bind to the SARS-CoV2 spike protein with high affinity, preventing cell infection. The biocompatible and stable nanostructures also show great potency in blocking viral particles.
Researchers have designed a solar harvester with enhanced energy conversion capabilities using self-assembling nanoparticles. The device achieves high absorbance and suppressed thermal emissivity, enabling the transformation of sunlight into thermal energy.
Carolina researchers have engineered silicon nanowires that can convert sunlight into electricity, splitting water into oxygen and hydrogen gas. This innovative design enables the production of a greener alternative to fossil fuels, making it more competitive with traditional energy sources.
A novel method has been developed to produce platinum-based alloy nanoparticles for efficient hydrogen fuel cells. The nanocatalysts exhibit enhanced power performance and stability, with high specific rated power of 5.9 kW/g Pt, surpassing 2025 targets set by the U.S. Department of Energy.
Researchers at Berkeley Lab have developed a new technique that captures real-time movies of copper nanoparticles as they convert carbon dioxide into renewable fuels and chemicals. The study reveals that metallic copper nanograins serve as active sites for CO2 reduction, paving the way for advanced solar fuel technology.
Researchers at Cornell University have discovered that metal oxide nanoparticles commonly used as food coloring and anti-caking agents can damage parts of the human intestine. The study, led by Elad Tako, found negative effects on key digestive proteins in chickens injected with the nanoparticles.
Researchers at the University of Sheffield have discovered that epoxy-functionalized nanoparticles can significantly reduce friction on stainless steel surfaces. The nanoparticles adhere strongly to metal surfaces due to chemical adsorption, leading to a notable reduction in friction. This finding has potential implications for next-ge...
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateFeb 1, 2023
Researchers at the University of Florida have found that silver nanoparticles and aminoglycosides work together synergistically to combat antibiotic-resistant bacteria. The combination reduces the amount of antibiotic needed by 22-fold, making it more potent and potentially reducing side effects.
Researchers discovered the most efficient way to produce ammonia through electrochemical synthesis, increasing its sustainability. The D5 step site on ruthenium nanoparticles was found to be the most active site for the nitrogen reduction reaction.
Scientists at MIT have designed a novel nanoparticle platform that can deliver optimal ratios of multiple cancer drugs, leading to enhanced efficacy and reduced side effects. The bottlebrush-shaped particles can be loaded with varying concentrations of drugs, enabling the precise delivery of synergistic combinations.
Scientists at Rice University, Stanford University, and UT Austin have developed a mechanism to generate solvated electrons through plasmon resonance, making it easier to turn light into these clean, zero-byproduct chemicals. This breakthrough could lead to new ways of driving chemical reactions and reducing greenhouse gas emissions.
Researchers developed a novel acid-resistant nanofiltration membrane for efficient treatment of acidic wastewater. The membrane shows high permeation for H+ while maintaining high retention for organics, making it beneficial for 'zero discharge' in strongly acidic organic wastewater reclamation.
Researchers at Hokkaido University have discovered a new pathway to forming presolar grains, which could help scientists better understand the interstellar environment and develop more efficient nanoparticles. The study suggests that these grains formed through a non-classical nucleation pathway, involving three distinct steps.
A genetically engineered bacterium has enabled the biosynthesis of melanin nanoparticles with excellent biocompatibility, stability, and photothermal conversion efficiency. The resulting nanoparticles showed strong absorption in the near-infrared region and high antitumor efficacy for photoacoustic imaging-guided photothermal therapy.
A team of researchers from Erlangen and Würzburg developed a method to bind specific molecules in samples and serums to iron oxide particles, allowing for their identification using an inexpensive and compact detector. This method enables highly sensitive measurements in a short time with little technical outlay.
A new approach to gene therapy for inherited blindness uses lipid nanoparticles to deliver mRNA inside the eye, targeting light-sensitive cells and creating proteins that edit vision-harming gene mutations. The technology has shown promising results in animal studies, including mice and nonhuman primates.
Researchers have made a key breakthrough in developing a new treatment for hereditary blindness by using lipid nanoparticles to deliver messenger RNA to the photoreceptor cells. The technology, inspired by COVID-19 vaccines, shows promise in animal models for treating blindness associated with rare genetic conditions.
A team at City University of Hong Kong has developed a novel approach to converting environmental temperature fluctuations into clean chemical energy using pyroelectric catalysis. By combining pyroelectric materials with localized plasmonic heat sources, the researchers achieved significantly faster and more efficient pyro-catalytic re...
Researchers at Ruhr-University Bochum develop base metal oxide nanoparticles that improve the water splitting process for green hydrogen production. Cubes outperform spheres as catalyst particles, increasing activity and efficiency.
Researchers at Washington University in St. Louis found that nanoplastics from polystyrene can produce reactive oxygen species when exposed to light, which can harm wildlife and the aquatic ecosystem. The study suggests that smaller particle sizes of nanoplastics may be more reactive and decompose faster under light.
Researchers have developed a novel near-infrared light detection method using core-shell lanthanide nanoparticles to convert weak near-infrared light to visible light with high efficiency. This achievement promotes the proposal of a new resource- and energy-saving near-infrared light detection method, improving optical sensor sensitivi...
Researchers at Kyoto University have developed nanoantennas that significantly increase the efficiency and photoluminescence of white LEDs by replacing aluminum with titanium dioxide. This breakthrough enables the creation of intensely bright yet energy-saving solid-state lighting solutions.
A new rapid test developed by the University of Würzburg uses magnetic nanoparticles to detect antibodies against SARS-CoV-2 with high sensitivity. The test takes only a few seconds to produce reliable results, enabling faster diagnosis and treatment of infectious diseases.
A recent study published in Scientific Reports found ultrafine magnetic iron oxide particles in London Underground air pollution, with average diameter of 10 nanometres. The authors propose that improved air pollution monitoring and efforts to reduce pollution levels could help mitigate health risks associated with exposure to these pa...
The São Paulo School of Advanced Science on Nanotechnology, Agriculture and Environment will cover topics such as nanotechnology innovation, sustainability, and biological applications. The event will feature renowned scientists as speakers and provide hands-on experiments, technical visits, and didactic activities.
Researchers at Notre Dame have discovered a way to enhance the effectiveness of existing drugs using a new 'raspberry-shaped' nanoparticle. By varying the loading procedure, they can create particles that release drugs at different rates.
A review suggests that inorganic nanoparticles can cross the placental barrier and enter breastmilk, potentially predisposing babies to food allergies. The study highlights the need for further research on the impact of nanoparticle exposure on children's health during a critical window of susceptibility.
Engineers at Duke University developed a device that separates and sorts tiny biological nanoparticles from blood using 'virtual pillars' created by sound waves. The technology, dubbed ANSWER, shows promise for diagnostics and treatments, with accuracy rates of up to 96%.
Researchers at Scripps Research developed nanoparticles that target only the immune cells driving an autoimmune reaction, delaying or preventing severe disease in a mouse model of arthritis. The treatment boosts regulatory T cell populations and reduces anti-self-antigen antibody production.
Researchers have discovered that nanodiamonds can emit solvated electrons in water when exposed to visible light, a crucial step towards using them as photocatalysts. This discovery could lead to the development of inexpensive and metal-free processes for converting CO2 into valuable hydrocarbons or converting N2 into ammonia.
Researchers at Bar-Ilan University have created functional, multi-layered neural networks that mimic elements found in the brain of mammals. The 'mini-brains' were generated through magnetic manipulations of neural progenitor cells in a three-dimensional collagen substrate.
Scientists at the University of Illinois have created a new strategy to build materials with unique properties by organizing nanoparticles into pinwheel shapes. The pinwheel lattice exhibits chirality, a property that can be seen in nature's examples such as DNA and human hands.
Researchers at University of Pittsburgh have designed novel nanoparticles that co-deliver a chemotherapy drug and a novel immunotherapy, shrinking tumors in mouse models of colon and pancreatic cancer. The therapy silences a gene involved in immunosuppression by blocking Xkr8 protein distribution on the cell membrane.
Nucleic acid therapies aim to treat genetic disorders and diseases, but delivering therapeutics is a significant challenge. Researchers are investigating nanoparticle delivery systems to target specific cells and sub-cellular compartments for effective delivery.
SourceWiley·JournalWiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology·DateNov 23, 2022
Researchers developed a nanoparticle-based approach that uses photoacoustic imaging and infrared light to detect and potentially treat ectopic pregnancies. The technology shows promise in mice studies and may offer a non-invasive and effective way to improve diagnosis and treatment of the condition.
Ectopic pregnancies are non-viable and the leading cause of maternal death in the first trimester, affecting 2% of all pregnancies worldwide. Researchers have developed a new method using light-sensitive nanoparticles to detect growing placentas and end ectopic pregnancies more effectively.
The study analyzed experimental parameters, nanomaterial types, and plant exposure duration. It found that many studies lacked positive controls and had short durations compared to crop lifecycles.
A new injectable hydrogel has been developed with enhanced shear-thinning properties, improved cellular biocompatibility, and significantly reduced clotting times. The biomaterial was created by adding sodium phytate to a gelatin-based compound, promoting even greater cohesion and triggering the initiation of blood coagulation.
Researchers at City University of Hong Kong found that tailoring cobalt concentration in high entropy alloys prevents nanoparticles from coarsening at high temperatures. This strategy opens a pathway for designing novel thermally stable chemically complex alloys for various engineering fields.
Researchers at Oregon State University have developed new, heat-efficient magnetic nanoparticles capable of reaching temperatures in cancer lesions of up to 50 degrees Celsius. The particles can be exposed to an alternating magnetic field, weakening or destroying cancer cells without causing harm to surrounding tissue.
Researchers in Singapore, Saudi Arabia, and Finland achieved first insights into engineering crystal growth by atomically precise metal nanoclusters. They synthesized gold clusters consisting of 25 atoms, regulating their size and concentration to form well-defined crystals with unique morphology.
Researchers at the University of Wisconsin-Madison develop nanoparticles to neutralize molecules implicated in IBD, significantly improving treatment outcomes. The probiotic bacteria are equipped with nano-backpacks that target reactive oxygen species, reducing inflammation and promoting weight gain and colon length restoration.
Researchers will develop a new model to describe complex soot particles in the atmosphere, improving accuracy in predicting climate warming caused by soot. The project aims to reduce uncertainty over soot's impact on climate change and air quality.
Researchers have developed a transport nanoparticle to deliver an anti-inflammatory drug, Necrosulfonamide (NSA), directly into macrophages to combat inflammatory overactivation. The mesoporous silica nanoparticle is fully biodegradable and non-toxic, showing remarkable efficacy in reducing inflammation.
Scientists at Ural Federal University have developed a sensor device that determines cholesterol levels without using enzymes. The system uses copper chloride, making the process cheaper, easier, and faster than traditional methods.
Researchers at Washington State University developed a new method to measure residual herbicides in fruits, vegetables, and their products using nanoparticles. The test is sensitive enough to detect chemicals down to maximum acceptable levels and is validated using traditional testing methods.
Researchers from Johannes Gutenberg University Mainz developed ceria nanoparticles to silence bacteria by modifying signaling molecules, preventing biofilm formation. This approach mimics nature's defense system and has potential for creating antibacterial surfaces without resistance.
Advanced nanoparticles carrying a bacterially derived compound target the STING pathway, disrupting blood vessels and stimulating an immune response. This approach suppresses tumor growth and metastasis in several types of cancers.
Oregon State researchers have engineered inhalable lipid nanoparticles that effectively deliver messenger RNA to the lungs, prompting lung cells to manufacture a protein needed to thwarts the disease. The therapy shows promise in treating cystic fibrosis, a progressive genetic disorder affecting 30,000 people in the US.
A research team at UNIST has developed a perovskite-silicon tandem solar cell with a special textured anti-reflective coating, increasing its power conversion efficiency to 23.50%. The device maintains its initial efficiency for 120 hours, outperforming existing devices which drop to 50% after 20 hours.