Engineers have developed a pill that releases microscopic robots to treat inflammatory bowel disease (IBD) in mice. The treatment significantly reduces IBD symptoms and promotes the healing of damaged colon tissue.
Researchers at IBS have developed a damage-free dry transfer printing technique for flexible electronic devices, overcoming existing challenges such as the use of toxic chemicals and mechanical damage. The new method allows for high-quality electronic materials to be transferred to flexible substrates without damage.
Xiaohu Xia's research focuses on enhancing diagnostic efficacy of enzyme-linked immunosorbent assay (ELISA) testing using specially tailored nickel-platinum nanoparticles. His goal is to improve disease detection accuracy by more than 300 times, enabling early diagnosis of cancers like prostate and colorectal cancer.
Researchers at Brigham and Women's Hospital have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The therapy shows promising results in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care...
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Researchers developed microscopic robots that swim through lungs to deliver cancer-fighting medication directly to metastatic tumors. The approach inhibited tumor growth and spread, improving survival rates compared to control treatments.
Scientists at Hokkaido University have created a new technique for building nanoparticles using enzymes, enabling the production of various nanomaterials with controlled size and properties. This method has potential applications in technology, medicine, and quantum computing.
Research suggests nanoparticles can disrupt placental function and affect embryonic development, leading to potential health issues such as low birth weight and respiratory diseases. The study used human placentas and found that nanoparticles can inhibit blood vessel formation via messenger substances.
Researchers at UTEP have developed a new therapeutic approach to treat skin and lung fibrosis by targeting and rehabilitating cells responsible for the disease. The nanoparticles successfully modified the cells to stop producing excess collagen, offering hope for improved treatments and enhanced quality of life.
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Researchers highlight strategies for improving agriculture with nanotechnology, including targeted delivery of pesticides and herbicides, and digital twin simulations. These approaches aim to reduce environmental pollution and increase crop resilience.
Researchers have discovered that a platinum nanoparticle catalyst can assemble and disassemble itself during reaction and post-reaction conditions. This reversible process may offer clues to the catalyst's stability and recyclability, with potential benefits for controlling long-term stability.
Researchers have developed a new perovskite-based camera inspired by the structures and functions of bird's eyes, specializing in object detection. The camera features an artificial fovea and multispectral image sensor that detects UV and RGB light, providing greater motion detection capabilities than conventional cameras.
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Researchers have designed a method to 'cloak' proteins for targeted delivery into cells, utilizing lipid nanoparticles. The cloaked proteins can be captured by the nanoparticles and exert their therapeutic effect once inside the cell. This approach shows promise for repurposing antibodies and other proteins for cancer treatment.
The review highlights the superior safety and efficacy of nanoparticle vaccines, which have shown potential in protecting against diseases like foot-and-mouth disease and swine fever. These nanovaccines harness the power of nanotechnology to revolutionize vaccine design and implementation.
The study reveals sulfur trioxide can form acid sulfuric anhydride products with organic and inorganic acids, contributing to atmospheric new particle formation. These findings improve aerosol formation prediction models, aiding in managing air pollution and mitigating climate change impacts.
Researchers at Rice University developed a new material that mimics skin elasticity and motion types while preserving signal strength in electronics. The material, made by embedding ceramic nanoparticles into an elastic polymer, stabilizes radio-frequency communication and minimizes energy loss.
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Researchers apply hydrophilic polymer coating to nanoparticles, reducing accumulation and toxicity in Caenorhabditis elegans. The coating mitigates NP bioavailability, promoting eco-friendly nanomaterials for environmental remediation.
A plant virus treatment, composed of cowpea mosaic virus nanoparticles, has shown remarkable success in improving survival rates and suppressing the growth of metastatic tumors across various cancer models. The treatment was effective even after surgical removal of tumors, indicating its potential to prevent metastasis.
Researchers at Oregon State University discovered that the shape and surface chemistry of silver nanoparticles significantly impact their environmental toxicity. The study, published in Nanomaterials, found that certain formats can preserve beneficial properties while limiting negative effects.
The study found that an 80% concentration of zirconium dioxide (ZrO2) and specific solvents leads to the highest pattern transfer efficiency. The conversion efficiency reaches impressive levels in the ultraviolet spectrum, paving the way for commercial viability of metasurfaces.
Researchers at Gwangju Institute of Science and Technology develop a new nanotechnology method that enables the creation of uniform, wafer-scale nanoparticle assemblies in just seconds. The 'mussel-inspired' technique accelerates assembly by introducing excess protons to increase electrostatic attraction.
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Scientists discovered that Cu nanoparticles supported on γ-Al2O3 surfaces can redisperse spontaneously at room temperature due to hydroxylation and formation of Cu-OH species. The O2 and H2O led to the transformation of Cu atoms into single atoms, enhancing catalytic activity in RWGS and CO-PROX reactions.
Researchers at Sylvester Comprehensive Cancer Center have developed a nanoparticle that can penetrate the blood-brain barrier, potentially targeting both primary breast cancer tumors and brain metastases in one treatment. The method shows early promise in preclinical models, where it shrinks breast and brain tumors.
Researchers at Oregon State University have developed a novel device that can improve the delivery of gene therapy for patients with inherited lung diseases such as cystic fibrosis. The device uses aerosolization technology to carry messenger RNA to patients' lungs, reducing shear stress and improving precision.
Researchers developed a new 'proactive vaccinology' approach to build vaccines before disease-causing pathogens emerge. The Quartet Nanocage vaccine trains the immune system to target specific regions of eight coronaviruses, providing broad protection against known and unknown strains.
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Researchers analyzed asteroid Ryugu samples to study magnetic and physical bombardment environment in interplanetary space. The investigation revealed changes likely caused by micrometeoroid bombardment, providing insights into the solar system's early stages.
Researchers have discovered that rice bran-derived nanoparticles exhibit strong anticancer effects, selectively targeting cancer cells while sparing healthy tissue. The nanoparticles reduced tumor growth and inhibited metastatic cell growth in mice models.
Researchers from the Institute for Basic Science created QLEDs using a ternary nanocomposite film that enhances carrier delivery to quantum dots, resulting in optimal device performance. The devices exhibit high brightness and low threshold voltage, with no damage when stretched up to 1.5 times.
A new 'rechargeable nanotorch' allows researchers to track the movement of cell-based microrobots in real-time, using afterglow luminescence imaging. The nanotorches can be recharged non-invasively with near-infrared light, enabling long-term tracking and potential applications in cancer treatment.
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Researchers have developed protein-based nanoparticles that target and destroy specific cancer cells, providing a more efficient treatment option. This technology uses natural secretory granules found in the endocrine system to deliver proteins over an extended period.
Purdue University researchers create biocompatible nanoparticles modified with ATP that slowly release anti-cancer drugs and recruit immune cells to fight tumors. In mouse studies, these nanoparticles improved the effectiveness of paclitaxel against various types of cancers, including those in distant locations.
Researchers at Stanford University have successfully 3D printed tens of thousands of Archimedean truncated tetrahedrons, a geometry predicted to produce promising new materials that can change form in an instant. These nanoparticles can shift between states rapidly by rearranging particles into new geometric patterns.
Researchers developed a self-cleaning wall paint using waste-valorized titanium oxide nanoparticles, which can bind and break down pollutants, and then degrade them when exposed to sunlight. The paint combines several advantages, including air pollutant removal, longer durability, and reduced production costs.
A new study by Duke University researchers provides fundamental insights into autoimmune diseases, including systemic lupus erythematosus. They developed a system to test how DNA attached to nanoparticles interact with the immune system, revealing that larger nanoparticles provide more protection for DNA.
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The Indian Institute of Science team developed a novel technique to fabricate structurally colored films with a liquid gallium metal and polydimethylsiloxane substrate. These films change color in response to mechanical deformation, showing potential applications in smart bandages, movement sensors, and reflective displays.
Researchers developed nanoparticles that effectively halt amyloid beta aggregation and toxicity using ultra-low-energy X-rays. The innovative treatment strategy shows promise in delaying disease progression by up to 36% in preclinical models.
A new nanoparticle-based therapy using Luminol-conjugated cyclodextrin (LCD) nanoparticles has shown significant improvements in treating severe burn-induced intestinal barrier disruption. The therapy promotes the repair and regeneration of tight junction structures, reducing inflammation and oxidative stress.
Scientists have created a new approach for treating tendon-bone injuries by combining manganese silicate nanoparticles with cells to create an immunomodulatory scaffold. This innovation promotes integrated regeneration and functional recovery in patients, offering a promising solution for improving life quality.
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Researchers developed a GPS nanoparticle platform that can home in on cancer cells to deliver gene-editing tools, targeting the protein implicated in tumor growth and spread. The technique may offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
The Access to Advanced Health Institute (AAHI) has received $12.7 million to develop a novel immune-stimulating adjuvant formulation, NanoAlum, which aims to improve vaccine protection against complex diseases like tuberculosis and influenza.
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Researchers at MIT have developed a new type of nanoparticle that can both deliver vaccines and act as an adjuvant to generate a strong immune response. The particles, called metal-organic frameworks (MOFs), were shown to be effective in delivering the SARS-CoV-2 spike protein and boosting the immune system's response.
Rice University researchers have developed a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures. This allows for modifying the structure of the oxide layer, making the nanoparticles versatile tools for different applications.
Researchers are developing minimally invasive techniques to repair and regenerate tissue in aortic aneurysms using actively targeted, drug-releasing nanoparticles. The team found that rod-shaped particles with high aspect ratios were selectively taken up by diseased endothelial cells, leading to improved therapy outcomes.
Researchers have made a breakthrough in developing genetic treatments for hereditary conditions like cystic fibrosis and inherited vision loss. They created a new type of lipid nanoparticle, called Thio-lipids, that can deliver therapeutic payloads to the lungs and retina.
Researchers demonstrate a way to amplify interactions between particles to overcome environmental noise, enabling the study of entanglement in larger systems. This breakthrough holds promise for practical applications in sensor technology and environmental monitoring.
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Researchers at the University of Pennsylvania have developed a new method to efficiently determine which lipid nanoparticles are likely to bind to the lungs, rather than the liver. This breakthrough enables targeted delivery of mRNA therapeutics beyond the liver, offering new hope for treatments of cystic fibrosis and lung cancer.
Researchers at the University of Pennsylvania School of Engineering and Applied Science have invented a new way to synthesize key components of lipid nanoparticles, simplifying their manufacture while boosting efficacy. The new method involves combining three chemicals to create branched lipidoids that promote mRNA delivery to target c...
A novel chemotherapy approach uses patient's own cells as Trojan horses to deliver targeted cancer-killing drugs to lung cancer cells. The method has shown promise in reducing tumor size and improving treatment efficacy with minimal collateral damage to healthy tissues.
Scientists create 'μkiss' technique for precise delivery of materials to individual cells, offering new possibilities in single-cell science and next-generation therapeutic applications. The method provides full control over location, time, and scale of material application, enabling detailed studies of cellular processes.
A new study aims to enhance and prolong vaccine effectiveness by delivering adjuvants to white blood cells using lipid nanoparticles. The research, led by WVU professor Sharan Bobbala, has the potential to provide broader protection against evolving viruses and multiple diseases.
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The VPNVax platform utilizes a modular approach to create viromimetic polymer nanoparticle vaccines with enhanced surface valence, demonstrating improved immune stimulatory effects. The research offers new insights into designing the next generation of VLP vaccines with increased durability and versatility.
Researchers have discovered a new way to target chemotherapy-resistant ovarian cancer cells by depriving them of cholesterol, leading to significant tumor growth reduction. The nanoparticles starve the cells of cholesterol, triggering cell death through oxidation of lipids in the cell membrane.
Researchers at São Paulo State University developed a novel technique using lipid nanoparticles to administer lupeol, killing Leishmania protozoan parasites. The therapy eliminated parasites from organs in animal tests, reducing spleen and liver parasite numbers by 99.9% with minimal side effects.
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A Husker research duo has won a $25,000 prize in the NIH’s Targeted Genome Editor Delivery Challenge. They will advance development of universal milk exosomes capable of transporting gene editors to any location in the body, overcoming a significant challenge in using gene editing to treat disease.
Researchers have developed a novel catalyst platform that enhances the selectivity of catalytic reactions by trapping nanoparticles to prevent agglomeration. The distance between particles plays a crucial role in determining the product yield, with increased separation leading to more efficient production of intermediate chemicals.
USC researchers have designed nanoparticles that can target and highlight cancer cells in lymph nodes, allowing for earlier detection of metastasis. The particles work by hitchhiking on immune cells to reach the lymph nodes, where they can amplify the signal detected by MRI scans.
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Researchers from Pohang University of Science & Technology employ linker ions to pioneer three-dimensional microprinting technology applicable to inorganic substances and other various materials. The team successfully crafts inorganic porous structures with dimensions below 10 μm without specialized equipment.
A team of researchers has developed a novel mixing device that produces nanomedicines directly at the point of care, enabling rapid and cost-effective synthesis of personalized vaccines. The technology has potential implications for cancer therapies and infectious diseases.
Researchers have identified nanoplastics in ocean water off the coasts of China, South Korea, and the US, with surprising diversity in shape and chemical composition. The tiny plastic particles, originating from consumer products, were found to be more toxic than larger plastic particles due to their small size.
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A new technique developed at INRS pushes back some of the limits of infrared imaging for rare-earth doped nanoparticles. The SWIR-PLIMASC system enables high-sensitivity and high-speed imaging, allowing for accurate information to be derived from photoluminescence lifetimes.