Articles tagged with Nanoparticles
Researchers at the University of Pennsylvania designed a new recipe for mRNA vaccines by adding phenol groups, which reduce inflammation and improve vaccine effectiveness. The modified lipids improved vaccine performance in various diseases, including COVID-19, cancer, and genetic diseases, with enhanced efficacy and reduced side effects.
Researchers detected nanoplastic particles smaller than 1 µm in all depths analysed across the 12 measurement sites, with PET, PS, and PVC being the most common types. The study estimates around 27 million tonnes of nanoplastic are stored in the uppermost water layer of the North Atlantic.
Researchers found that sewage spills from land to sea coincided with winds of at least 6.5m/s on 178 days within a two-year period, potentially sending microplastics into the air. The study suggests that coastal towns and cities may be exposed to billions of airborne microplastic particles.
Researchers at Case Western Reserve University have received an NSF CAREER Award to develop synthetic DNA nanoparticles with potential applications in gene therapy. The program aims to study how these particles behave inside cells and potentially design therapeutics for genetic diseases.
Scientists developed a method to use ultrasound to chemically activate drugs, selectively targeting tumors and stimulating immune cells. This approach achieved a 99% tumor suppression rate in colon cancer models without harming healthy tissues.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
Scientists at Xi'an Jiaotong-Liverpool University developed a new nanoparticle capable of carrying high doses of chemotherapy drugs while staying stable for extended periods. This innovation could make treatments more effective and reduce side effects.
Researchers have developed a technique to observe phonon dynamics in nanoparticle self-assemblies, enabling the creation of reconfigurable metamaterials with desired mechanical properties. This advance has wide-ranging applications in fields such as robotics, mechanical engineering, and information technology.
A new study reveals how nanoparticles can interfere with photosynthesis in plants, reducing their ability to convert sunlight into food. The research team found that nanoparticles undergo changes in pH and pick up lipid coatings from plant membranes, boosting their binding to RuBisCO and impairing its function.
Researchers developed self-propelled ferroptosis nanoinducers to enhance cancer therapy by inducing programmed cell death. The nanotherapeutics exhibited enhanced diffusion and deep tumor penetration while maintaining biocompatibility.
Researchers at NYU Abu Dhabi have developed a breakthrough paper-based diagnostic device that can detect COVID-19 and other infectious diseases in under 10 minutes. The Radially Compartmentalized Paper Chip (RCP-Chip) is a fast, affordable, and portable solution for on-site screening of infectious diseases.
Researchers have developed a material that can collect moisture from the air and release it onto surfaces without external energy input. The material works through capillary condensation, where water vapor condenses inside tiny pores at lower humidity levels, creating a feedback loop of water harvesting.
A team from The University of Osaka has developed an efficient non-precious metal catalyst for converting biomass-derived furfural to tetrahydrofurfuryl compounds, achieving high yields under mild conditions.
Scientists from the University of Tokyo have created a filter that can capture nanoparticles such as viruses while maintaining air flow, resulting in improved user comfort. The filter uses nanosheets with porphyrin molecules and is capable of achieving a particle filtration efficiency of 96%, exceeding N95 mask requirements.
Researchers found that nanoplastics with positively charged surfaces caused physiological stress in E. coli O157:H7, leading to increased Shiga-like toxin production. The bacteria's ability to colonize and multiply was also impaired.
A recent study identifies LPCAT1 as a critical culprit in TNBC's aggressive behavior, which can be silenced with siRNA-delivering nanoparticles. This approach starves tumors of their energy supply, dramatically reducing tumor growth and lung metastasis.
Researchers created a new nanoparticle that combines focused ultrasound and chemotherapy to destroy tumors more precisely and prevent recurrence. The treatment shows promising results in preclinical models, offering a potential breakthrough in cancer therapy.
Researchers found four types of aircraft engine exhaust particles, including soot, volatile particles, and onion-like structures. The onion-like particles are composed of organic compounds and have unique internal structures that may affect their volatility and interaction with the human respiratory tract.
The researchers developed a next-generation AI electronic nose that can distinguish scents like the human olfactory system and analyze them using artificial intelligence. The device uses a laser to process a thin carbon-based material and incorporates a cerium oxide nano catalyst to create a sensitive sensor array.
Researchers create silk iron microparticles that can be guided using a magnet to deliver drugs and treatments precisely to sites in the body. The development has potential applications in regenerative medicine, cancer therapies, and cardiovascular disease treatment.
Researchers at JAIST have developed a low-dose imaging technique that maps the three-dimensional atomic structure of titanium oxyhydroxide nanoparticles without damaging them. This breakthrough enables safer analysis and opens possibilities for designing materials with enhanced functionality.
Researchers at UCLA developed a novel catalyst design that shields platinum from degradation, enabling fuel cells to power heavy-duty trucks reliably for up to 200,000 hours. This breakthrough could make hydrogen fuel cells a more viable clean energy source for long-haul trucking.
Researchers develop nanoparticle-based therapy combining hydroxyl-enriched fullerenol and mTOR inhibitors to disrupt cancer cells' organelle communication system. The approach triggers a synergistic "nanomaterial + metabolic modulation" anticancer strategy, establishing a new hope for treating aggressive cancers.
Researchers at Michigan Medicine have created nanodiscs that can target cholesterol levels in glioblastoma, starving cancer cells and increasing survival rates of treated mice. The combined treatment with radiation therapy was able to preserve normal brain structure and elicited an immunological memory.
Researchers developed a novel anode material combining hard carbon with tin, enhancing energy storage and stability. The composite structure shows excellent performance in lithium-ion and sodium-ion batteries, promising applications in electric vehicles and grid-scale energy storage.
The companies have created a microfluidic device-based LNP production system that enables precise control over particle size, addressing previous productivity issues. The system can produce various types of LNPs in small-batch or mass quantities, from personalized medicine to vaccines for infectious diseases.
Researchers developed a dual-action nanotherapy that converts white fat into beige fat and reduces obesity-related inflammation, significantly improving metabolic health without detectable toxicity.
Researchers found that nanoplastics in soil exhibit varying behavior depending on soil type and pH levels, affecting their aggregation and adsorption onto soil particles. Understanding these interactions is crucial for developing effective strategies to mitigate plastic pollution.
A new study by Columbia University researchers reveals that 75-80% of plastics, known as semicrystalline polymers, break down into hazardous micro- and nanoscopic fragments. These fragments can persist in the environment for centuries and cause significant damage to living things.
Researchers have found that oxalic acid can generate nanoparticles of the toxic metal gadolinium in human tissues, which has been associated with serious health problems such as nephrogenic systemic fibrosis. This discovery may lead to a possible way to mitigate some of the risks associated with MRI scans.
Researchers at MIT have developed a method to mass manufacture nanoparticles that target cancer cells, eliminating the need for manual polymer mixing and streamlining production. This approach integrates good manufacturing practice (GMP)-compliant processes, making it suitable for large-scale production of cancer treatments.
Researchers developed bacteria-enhanced graphene oxide nanoparticles that effectively destroy tumors through a three-pronged mechanism. The nanocomposites combine chemotherapy, immune activation, and photothermal heating to suppress tumor growth and activate strong immune responses in mice.
A new class of zwitterionic phospholipids, DOPE-Cx, enhances the functional delivery of mRNA via lipid nanoparticles, overcoming endosomal escape and improving mRNA expression. This breakthrough paves the way for advanced therapeutic applications, including mRNA vaccines, cancer treatment, and protein replacement therapy.
Researchers at University of Nottingham use transmission electron microscopy to observe real-time growth and contraction of Palladium nanoparticles. The study reveals a unique cyclic process where nanoparticles grow, dissolve, and re-grow, potentially leading to the development of new efficient catalysts.
Researchers developed a strategy to regulate hydrogen bond networks at electrolyte-electrode interfaces, accelerating proton transfer in CO2 reduction reactions. The approach involves introducing extra catalytic centers, such as cubic phase molybdenum carbide, to enhance water dissociation and facilitate proton generation.
Conjugated small molecular nanoparticles (CSMNs) have shown promise in near-infrared phototheranostics (NIR PTs) for imaging, therapy, and synergistic treatment. Strategies to improve performances and extend absorption wavelengths are crucial for their clinical translations.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
Researchers at Oregon State University have developed uniquely shaped, fast-heating nanoparticles that can effectively treat ovarian tumors. The nanoparticles exhibit exceptional heating efficiency when exposed to an alternating magnetic field, raising temperatures by 3.73 degrees Celsius per second.
A new bacterial protein, BeeR, has been identified and its structure is being used to develop protein nanoparticles for targeted cancer drug delivery. The protein forms a hollow tube with a cavity capable of containing drug molecules.
A new study found that adding green-synthesised iron nanoparticles (G-nFe) to pig manure neutralises bioavailable copper, reducing environmental risks. The process reduces exchangeable cooper by 66.8%, carbonate-bound copper by 47.5%.
Researchers at the University of Birmingham have developed a new method for rapid scalable preparation of uniform nanostructures directly from block polymers, significantly reducing processing time from weeks to just minutes.
A study by Pusan National University uncovers the impact of nanoplastic exposure on red blood cell maturation in zebrafish embryos. Exposure to polystyrene nanoparticles disrupts normal blood cell development, leading to an increase in immature RBCs and a decrease in mature RBCs.
Researchers have developed an innovative acoustofluidics-based approach for delivering biomolecular cargos into cells, overcoming limitations of traditional methods. The new method enables controlled contact between cells and nanoparticles, enhancing membrane permeability and improving delivery efficiency.
Magnetic nanoparticles are guided to tumors using a magnet and heated by a laser to destroy cancer cells. Researchers developed nanoparticles that outperform conventional photothermal agents, killing cancer cells with high efficiency.
Researchers developed a nanoparticle that delivers an mRNA vaccine targeting a KRAS antigen, boosting the immune response against pancreatic cancer. Experiments in mice showed inhibited and prevented tumor growth, as well as long-term protection against recurrence.
Core-shell nanoparticles offer effective drug encapsulation, shielding from degradation, and controlled release. This innovation enables targeted drug delivery, improving treatment outcomes and reducing side effects. The versatility of these nanoparticles allows for tailored materials to suit different therapeutic needs.
The study resolves a long-standing challenge in observing nanostructures and enables real-time tracking of three-dimensional atomic structural changes in individual nanoparticles. Researchers successfully captured the precise moments when surface atoms detached, rearranged, or reattached in three dimensions.
Researchers have developed an AI method to illuminate nanoparticle behavior, revealing key dynamics and instabilities. The technique combines electron microscopy with AI to capture atomic-level structural changes at unprecedented time resolution.
Researchers have discovered a way to trap iodine in perovskite solar cells using alumina nanoparticles, enhancing lifespan and stability. The modified solar cells maintained high performance for over two months under extreme conditions.
Researchers used molecular modeling techniques to understand nanoplastic interactions with natural organic matter in aquatic ecosystems. The study found that aged nanoparticles form stable aggregates through a combination of intermolecular forces, including hydrogen bonding and cation bridging.
Researchers developed new photon avalanching nanoparticles that exhibit high nonlinearities, overcoming challenges in realizing intrinsic optical bistability at the nanoscale. The breakthrough paves the way for fabricating optical memory and transistors on a nanometer scale comparable to current microelectronics.
Scientists at Nagoya University developed a nanoscale video game that manipulates nanoparticles in real-time, enabling interaction between virtual and physical objects. The 'nano-mixed reality' system has potential applications in nanotechnology and biomedical engineering, including 3D printing and targeted virus killing.
Deep Nanometry enables high-speed analysis of nanoparticles, detecting even trace amounts of rare particles like extracellular vesicles indicative of colon cancer. This technique has potential applications in various fields including vaccine development and environmental monitoring.
Researchers have developed a novel LiMn₂O₄ electrode material with improved lithium extraction capacity and cycle stability. The SnO₂ nanoparticle island-modified LMO electrode material shows good selectivity and stability for lithium ions, enabling efficient electrochemical salt lake lithium extraction.
University of Queensland researchers have successfully introduced genetic material into plants via their roots using nanoparticle technology, enabling rapid crop improvement. This innovative approach could lead to the development of new crop varieties with improved yield and quality without traditional breeding methods.
A new study published in Nature Materials demonstrates a lipid nanoparticle system capable of delivering messenger RNA to the brain via intravenous injection. The technology could pave the way for future treatments for conditions like Alzheimer's disease and drug addiction.
Researchers unveil Ba-Si orthosilicate oxynitride-hydride as a transition metal-free catalyst, offering a more sustainable approach to ammonia production. The novel catalyst demonstrates exceptional stability and higher activity than conventional ruthenium-loaded MgO catalysts.
Researchers detect nanoplastic particles on glaciers in France, Italy, and Switzerland, suggesting sea pollution as the source. The concentrations of nanoplastics varied between locations, with wind direction affecting their accumulation.
Researchers at the University of Konstanz developed an AI system to speed up nanoparticle measurements, reducing time from hours to minutes. The system, based on Meta's open source AI technology, can accurately count complex particles and measure individual particles with high precision.
The Terasaki Institute for Biomedical Innovation has announced the recipients of its inaugural Keith Terasaki Mid-Career Innovation Award. Dr. Liangfang Zhang and Dr. Aydogan Ozcan were recognized for their innovative approaches to translating groundbreaking research into real-world impact.