Articles tagged with Fluorescence
Researchers demonstrate simultaneous imaging of up to 6 subcellular targets with low crosstalks and high temporal resolutions. They achieve full-frame high sensitivities in quantifying mitochondrial matrix pH and intracellular macromolecular crowding.
Osaka University researchers used a photostabilizer to modulate fluorescence blinking in biochemical assays, allowing for the detection of a cancer RNA biomarker at ultralow concentrations. The technique increases fluorescence and eliminates blinking, providing a clear means to diagnose diseases in early stages.
Researchers at ETH Zurich have developed an approach to generate a broad palette of colours by adjusting the chemical structure of molecules themselves. By varying the chain length of fluorescent organic polymers, they can produce polymers with different colours, including yellow, green, and blue.
Researchers at Hokkaido University have developed a technique to manipulate nanodiamonds with fluorescent centers using opposing lasers. This breakthrough enables the independent control of resonant and non-resonant nanodiamonds, which can be sorted based on their optical properties.
A new recurrent neural network framework enables fast and efficient 3D imaging of fluorescent samples, reducing scan times by ~30-fold. The approach uses few 2D images to reconstruct 3D images, mitigating photo-bleaching challenges in live sample experiments.
Scientists used laser imaging and fluorescent particles to study water flow in tire grooves, finding vortices and bubbles that can contribute to hydroplaning. The study's findings may help improve tread designs to counteract this phenomenon.
Researchers discovered that photobleaching can transform fluorescent dyes into new molecules with altered fluorescence spectra, affecting microscopy results. Simple buffer additions can prevent or even exploit this effect for targeted tracking of specific particles.
A new plasmonic metasurface achieves unprecedented centimeter-scale efficiency, boosting absorption and emission of light. This design overcomes limitations of nanoscale properties, enabling practical applications in ultrafast optoelectronics devices and fluorescence-based biosensors.
Scientists from Japan develop a novel approach to acquire fluorescence lifetime images without scanning, using optical frequency combs and high-speed single-point photodetectors. This method offers superior speed and high spatial resolution for simultaneous imaging of multiple samples.
Researchers at Umeå University discovered a photosynthetic shortcut in pine trees that allows them to stay green year-round. This mechanism, called spill-over, enables the transfer of energy directly between photosystems I and II, protecting the plant from damage caused by excess light energy.
Researchers have discovered a new class of fluorescent dyes that can convert visible light into ultraviolet light, overcoming one of the biggest challenges to harnessing sunlight for energy. This breakthrough could enable more efficient solar-powered water splitting and other high-energy reactions.
A new study by UCL researchers used quantum sensing abilities of nanodiamonds to improve the sensitivity of paper-based diagnostic tests, enabling earlier detection of diseases such as HIV. The tests can detect lower viral loads and may be adapted for COVID-19 and other diseases.
Researchers from Tokyo Institute of Technology developed a method to measure polymer breakdown using a fluorescent molecule, enabling the estimation of resistance to mechanical stress. This breakthrough allows for the evaluation of polymer performance and specificity, paving the way for improved material design.
Scientists have created extremely stable fluorescent molecular switches that can be controlled electrochemically, using a particular redox active anion. These systems show large reversible fluorescence modulation and are soluble in many organic solvents, making them suitable for applications in biosensing, imaging, and drug delivery.
Researchers aim to understand how electrical stimulation affects glia and vasculature in the brain, with potential implications for treating neurological diseases. They'll use two-photon microscopy and optogenetics to investigate inner workings of the brain.
Researchers developed a novel γ-radiation intensity sensor using polymethylmethacrylate and polyvinyl chloride membranes. The sensor changes color in response to increasing radiation intensity, allowing for quick and easy measurement.
A new microendoscope combining photoacoustic and fluorescent imaging has been developed, enabling the measurement of blood dynamics and neuronal activity simultaneously. This innovation could advance our understanding of the brain's structure and behavior in specific conditions.
Researchers at the University of Notre Dame created a new class of near-infrared fluorescent dyes by introducing a voluminous shield to protect against photobleaching. The dye, called s775z, provided stable fluorescence and was quickly cleared from the body, making it suitable for biomedical imaging applications.
Researchers at Duke University use plasmonics to boost fluorescence in diagnostics, increasing test brightness by over 150 times. The approach could make point-of-care diagnostics more widespread and affordable.
Researchers have identified a new fluorescent compound in scorpion exoskeletons that could help guard against parasitic infections. The compound, a phthalate ester, was found to have antifungal and anti-parasitic properties, suggesting a potential defense mechanism for scorpions.
A study reveals biofluorescence is widespread among amphibians, including salamanders and frogs, which may aid in finding each other and avoiding predators. The phenomenon's mechanisms are linked to the presence of fluorescent proteins and compounds in skin, secretions, and bones.
Researchers used ghost imaging to enhance the speed of super-resolution microscopy, achieving nano-scale resolution in just 10 image frames. The new approach resolves structures with spatial and temporal resolutions at which biological processes take place.
A Chinese research team has developed a new technique that enables super-resolution microscopy of living cells with unprecedented speeds and resolutions. The approach, which combines ghost imaging and compressive imaging, can capture processes in living cells on millisecond time-scales with spatial resolution of tens of nanometers.
Researchers have developed ultrasensitive nanoscale optical probes to monitor the bioelectric activity of neurons and other excitable cells. The new technology could enable scientists to study neural circuits at an unprecedented scale, leading to powerful brain-machine interfaces.
Research at Earlham Institute reveals that plant clocks oscillate faster as plants age, with wheat exhibiting more rapid oscillations under constant darkness. The study uses delayed fluorescence to measure daily patterns in crops, enabling breeders to select optimal clock rhythms for improved yields.
Researchers from the University of Helsinki developed a new method to measure chlorophyll fluorescence in trees, revealing information on plant performance and structure. The technique uses LED technology to light up the forest at night, allowing for easier interpretation of data.
Scientists have developed a new charge transfer and separation process called Twisted Intramolecular Charge Shuttle (TICS) that enables faster energy conversion in solar cells and photosynthesis. TICS molecules exhibit a bidirectional, role switching phenomenon, paving a new avenue for chemists to construct unique fluorescent probes.
Researchers developed a first-of-its-kind elastic polymer blend that displays white fluorescence when deformed and then goes dark after relaxing. The material's color can be tailored by using different fluorescent rings, enabling the creation of a white-light-emitting polymer.
Researchers found that tiny Brazilian frogs, called pumpkin toadlets, have fluorescent patterns on their backs and heads when exposed to UV light. These patterns are created by bony plates beneath a thin layer of skin, allowing the frog's skeleton to glow under UV illumination.
Researchers have developed tiny 'blinkers' that can image single molecules of RNA or protein inside cells simultaneously, opening up new possibilities for diagnostics and treatments. The approach uses fluorescent probes that blink with variable duration and frequency to detect dozens of biomolecules at once.
Researchers at NIST have developed a new imaging technique that can observe the effects of strain at the single-molecule level, allowing for better design of composite materials. The technique uses super-resolution optical microscopy to track the alignment of molecules in response to applied force.
Scientists have created a novel tool that can both control and visualize serotonin receptor signals in neural cells using light. The tool, called Camello, uses fluorescent proteins to indicate activated signalling pathways and receptor trafficking in specific domains.
Researchers developed a method using fluorescent compound AggTag to identify intermediate forms of proteins that misfold and aggregate in live cells, which are believed to contribute to neurodegenerative diseases such as Alzheimer's and Parkinson's. The method allows for simultaneous detection of multiple proteins with distinct colors.
Researchers discovered that corals emit green fluorescence, attracting symbiotic dinoflagellates and potentially aiding coral recovery after bleaching. This biological signal enhances the chances of meeting new symbionts, suggesting a possible mechanism for corals to recover from heat stress-induced losses.
Researchers discovered that corals use green fluorescent light to signal the presence of Symbiodinium, a type of mobile microalgae critical to the establishment of a healthy partnership. The study found that this 'positive phototaxis' mechanism enables corals to attract Symbiodinium, which provide essential nutrients via photosynthesis.
Reef-building corals use green fluorescent protein to lure in photosynthetic symbionts. The study found that corals emit green light, which attracts Symbiodinium algae, increasing their density by 10-fold.
Researchers from Wuhan University developed a new type of upconversion nanocrystal that can display full-color patterns and multiple encoding levels. The material has excellent upconversion fluorescence properties under near-infrared laser excitation, making it suitable for high-security anti-counterfeiting applications.
A team of researchers discovered that flowering plants exhibit a morning peak of gene activity, contrary to the previously established evening peak theory. The study, conducted in natural environments, suggests that artificial growing conditions used in labs may have influenced earlier findings.
A new patch developed at Washington University in St. Louis increases fluorescence intensity by 100 times, making it easier to visualize and diagnose low-abundance analytes. The plasmonic patch is a cheap fix that can be applied to existing diagnostic tests without requiring any protocol changes.
ORNL's invisible micro-taggant technology uses an infrared marker for identification, providing a unique coding system that can identify item source, type, production, and composition. The taggant can be implemented in various products, including textiles, with a low production cost per taggant.
Researchers at Oregon State University discovered that bees are attracted to blue fluorescent light, particularly within a specific wavelength range of 430-480 nanometers. This finding has significant implications for bee population assessment and manipulation, such as attracting large numbers of bees for crop pollination.
Researchers found that TMS facilitates the reorganization of neuronal connections in the visual cortex, which could be beneficial for therapies. A short visual training after TMS treatment can remodel the maps and incorporate biases in information content.
A new surgical imaging instrument using Scanning Fiber Endoscope (SFE) technology has been developed to detect the fluorescent glow of malignant brain tumors. This allows neurosurgeons to visualize the tumor more accurately, enabling them to remove more tissue and potentially improve patient outcomes.
Scientists have created an ultra-thin fiber-based endoscope that can image neurons firing in living mice, offering new insights into brain function. The device is five times thinner than the smallest commercially available microendoscopes and allows for deeper brain imaging without damaging tissue.
Chameleons' bony tubercles on their heads emit blue fluorescent light when exposed to UV, creating distinct patterns that aid in species recognition. This phenomenon was previously unknown and is believed to play a role in mate attraction.
Researchers at Kyushu University developed a method to tune the fluorescence wavelength of carbon nanotubes by tethering organic molecules. This enables fine control over the emission wavelength, with potential applications in biomedical devices and bioimaging.
Researchers at Kyushu University used spectro-electrochemistry to investigate the frequency shifts in infrared fluorescence of modified carbon nanotubes. They found that the gaps between electron energy levels depend on the elements bonded to the exterior of the nanotubes.
A new technique for synthesizing thiophene derivatives has been developed, offering a convenient and effective two-step procedure. The compounds exhibit promising photophysical properties, including fluorescence, making them suitable for various applications, including OLEDs and potential biomedicine uses.
North Carolina State University researchers have developed a novel microfluidic platform called NanoRobo, which can collect up to 30,000 spectrographic information points per day. This technology enables the rapid discovery and screening of colloidal semiconductor nanocrystals, such as perovskite quantum dots, used in LEDs.
Researchers from MSU and Denmark have discovered the mechanism behind green fluorescent protein's sensitivity to light exposure. They found that an isolated chromophore group can emit light outside the protein environment, while the protein enhances its fluorescent properties.
Researchers at the Hebrew University of Jerusalem created a nanophotonic chip system using lasers and bacteria to observe fluorescence emitted from a single bacterial cell. The system enables efficient and portable on-chip sensing applications, including detecting chemicals in real-time.
Hybrid materials combining organic and inorganic components show promise for various applications, including optics and biomedicine. The materials display enhanced photophysical properties, such as anisotropic response to polarized light and artificial antenna effects.
Researchers at Osaka University developed artificial fluorescent membrane lipids that mimic sphingomyelin and interact with proteins, enabling the study of complex cellular processes. The findings reveal dynamic behavior of SMs associated with CD59 and plasma membranes, offering insights into modifying molecular interactions.
A new study by University of Notre Dame researchers has led to the development of a test kit for detecting influenza using fluorescent light. The test kit emits red fluorescence when exposed to infected patient samples, indicating the presence of the virus.
Researchers have developed a simple, low-cost device that can detect oil spills in water and pinpoint the type of oil involved. The device uses fluorescence spectrum analysis to identify five types of oil tested in the study.
Researchers have developed a non-destructive imaging technique to accurately determine the sex of baby chickens within four days of hatching, promising to reduce animal welfare concerns. The technique uses optical spectroscopy to identify gender-specific biochemical differences in embryonic blood, with an accuracy rate of 93%.
The new method minimizes waste generation and energy consumption, allowing for the recycling of rare-earth metals at a higher rate. By pairing specific ions, the researchers can filter out individual metal cations, enabling their separation and recovery.
A new polarization-dipole azimuth-based super-resolution technique has been proposed, addressing a long-standing debate on the role of fluorescence polarization in super-resolution imaging. The technique uses SDOM technology to improve spatial resolution and detection accuracy, revealing interesting findings in biological samples.
Researchers at the University of Chicago created a new tool to view the spectrum from specific structures within samples. The instrument, a spatially selective microscope, allows users to zero in on the spectrum from specific regions of interest and capture standard fluorescence images of the whole field of view.
Scientists at MIT and Harvard University developed a new imaging technique called LASE microscopy, which uses tiny particles to create sharper images of deep tissue and cells. The particles emit laser light when stimulated by a laser beam, resulting in higher-resolution images.