Articles tagged with Fluorescence
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers develop novel technique that combines fluorescent dyes and human skin cells to analyze toxic chemicals. The method provides high accuracy and could reduce the use of laboratory animals in biomedical research.
A study by London researchers found that standard radiation margins may not be large enough for all patients with non-melanotic skin cancer. Using protoporphyrin fluorescence, the team was able to determine more precise treatment volumes, resulting in improved patient outcomes and reduced recurrence rates.
Researchers develop a simple, single-component fluorescence system that glows in response to microscopic damage, allowing for early detection. The method works for various materials and types of damage, including small cuts, and could reduce inspection costs.
Researchers at Northwestern University discovered that DNA naturally fluoresces under certain conditions, allowing for label-free super-resolution imaging without the need for toxic fluorescent stains. This breakthrough could revolutionize the understanding of biological processes by providing more accurate images of living cells.
Researchers developed a new method to capture three views simultaneously, producing more detailed perspectives of bacteria and living cells. The technique improved volumetric resolution by up to 235nm, doubling the resolution of traditional methods.
Researchers at Caltech use DNA origami to precisely place glowing molecules within microscopic light resonators, creating a microscopic reproductions of Vincent van Gogh's The Starry Night. By mapping out a checkerboard pattern of hot and cold spots, they can position fluorescent molecules to make lamps of varying intensity.
Biologists from Moscow State University found new luminescent creatures in the Red Sea, with unique fluorescent patterns that can help identify different species. The study published in PLOS ONE reveals insights into the role of glow in attracting prey and exploring symbiotic relationships.
The Molecular Spectroscopy Group has created new multifunctional materials that mimic the photosynthetic organisms of plants. These materials capture a broad spectral range of light and convert it into chemical energy. They have been applied in various photonic applications, including tunable lasers and light modulators.
MIT researchers develop a low-cost biomedical imaging system using fluorescence lifetime imaging and Fourier transform analysis, enabling accuracy comparable to expensive lab equipment.
Scientists at ITbM developed a new fluorescent dye, C-Naphox, with enhanced photostability to enable continuous live cell imaging by STED microscopy. The dye has demonstrated extreme photoresistance and no significant toxicity towards cells, opening doors to real-time biological event observation for extended periods.
Researchers at UC Santa Cruz and Brigham Young University have developed a novel method for multiplex fluorescence detection on a small chip, enabling the rapid detection and identification of different flu virus subtypes. The technique uses wavelength division multiplexing to create distinctive signals in an optical waveguide.
Researchers at EPFL have created a groundbreaking DNA stain called SiR-Hoechst, which enables the safe imaging of living cells for extended periods. This innovation allows biologists to track biological processes such as cell division in real-time, paving the way for further breakthroughs in bioimaging.
Researchers at the Howard Hughes Medical Institute's Janelia Research Campus have developed new imaging techniques that dramatically improve spatial resolution in living cells. The new methods offer extraordinary visual detail of structures inside cells with unprecedented clarity and speed.
Researchers have induced structures within cells to produce laser light, emitting specific wavelengths that allow for precise labeling and measurement of individual cells. This technology has the potential to tag up to a trillion cells, matching the estimated number of human body cells, enabling applications in basic research and disea...
Researchers from the University of Southampton and international partners discovered glowing corals with a range of fluorescent colours in deep waters of the Red Sea. The team hopes that these pigments could be developed into new imaging tools for medical applications.
Scientists at Northwestern University invented fluorescent inks that can be used as multicolored barcodes to authenticate products. The inks are invisible under normal light but visible under ultraviolet light, making them difficult for counterfeiters to mimic.
Researchers used X-ray fluorescence to visualize structural damage in lithium-ion batteries due to fast charging cycles, leading to reduced storage capacity. The study found that even a few charging cycles cause damage to the inner structure of the battery material.
Researchers at Tel Aviv University have developed a novel DNA-peptide structure that can be used to produce thin, transparent, and flexible screens. The new material is light, organic, and environmentally friendly, emitting a full range of colors in one pliable pixel layer.
Researchers found that fluorescent properties of edible food colors increase with the viscosity of surrounding fluids, suggesting they could act as embedded sensors for food's physical consistency. This could provide a less invasive and more accurate way to test food quality, potentially revealing changes in spoilage or consistency.
Duke University researchers have developed a way to increase the photon emission rate of fluorescent molecules, reaching record levels. This breakthrough has significant implications for ultrafast LEDs and quantum cryptography, enabling secure communication that could not be hacked.
Researchers developed a technique that uses fluorescence lifetime measurements to automatically sort plastics, reducing contamination levels and increasing re-use efficiency. The new method can process up to 1.5 tons of plastic per hour, meeting industrial scale requirements.
Researchers deciphered structural components of fluorescence brightness in a primitive sea creature, known as lancelets or amphioxus. The study found that changes in stiffness around the chromophore pocket enable the animal to emit different brightness levels.
Researchers at EPFL create two powerful probes for the imaging of cytoskeletal proteins with unprecedented resolution. These probes provide a significant improvement over existing techniques, enabling easier and higher quality imaging of cells with minimal toxicity.
Scientists have discovered molecules that may block the accumulation of a toxic eye protein leading to early onset glaucoma. The researchers identified two compounds with potential for future drug development to treat this condition, which affects several million people from childhood to age 35.
Scientists have developed a new type of molecular motor made of DNA that can transport nanoparticles along the length of a carbon nanotube. The motor uses energy from RNA molecules to fuel its movement, which is controllable and adaptable to changes in the local environment.
Researchers developed a fluorescent caffeine detector that lights up like a traffic light to indicate the amount of caffeine in drinks. The sensor can help prevent caffeine overdoses and is useful for detecting pollution in natural water systems.
A study published in PLOS Biology reveals how death spreads through an organism like a wave, using blue fluorescence as a visual cue. The researchers found that a specific chemical pathway called necrosis is responsible for this process, which is dependent on calcium signalling.
Coral reefs are evaluated using fluorescence levels which decrease with stress and increase before bleaching, making it a non-invasive early indicator of coral health. This novel method improves on current testing technologies and could aid in reef conservation efforts.
The new device uses a polymer sheet with fluorescent particles to capture incoming light and channel it to an array of sensors. This allows for the creation of high-resolution images without any internal components or electronics. The technology has potential applications in user interface devices that can respond to gestures alone.
Scientists at Wake Forest University have developed a flicker-free and shatterproof lighting solution using field-induced polymer electroluminescent (FIPEL) technology. The new lights produce soft white light without the yellowish tint of fluorescents or bluish tinge of LEDs.
Researchers at Harvard's Wyss Institute engineer a new kind of DNA barcode that can come in an almost limitless array of styles, allowing for vastly more vital information to be gathered from cell samples. The method harnesses the natural ability of DNA to self-assemble, enabling low-cost and robust cellular imaging.
A new device developed by researchers in Israel can reveal vital medical information from a single drop of blood in real-time. Using spectrally encoded confocal microscopy, the device creates high-resolution images of individual blood cells flowing through veins without the need for fluorescent dyes.
Researchers have created a new cyan fluorescent protein (CFP) called mTurquoise2, which triples the fluorescence efficiency of existing proteins, enabling improved cellular imaging with unprecedented sensitivity. This breakthrough allows scientists to study protein-protein interactions in living cells with increased accuracy and detail.
Micro-cavity arrays, pioneered by Air Force research, utilize micro-plasmas for efficient and environmentally friendly lighting. The technology boasts high utilization efficiency, is fully dimmable, and has a high Color Rendering Index, approaching sunlight quality.
Experiments tested sweetpotato whitefly preference for cucumber seedlings grown under fluorescent lamps with high red:far red ratio or metal-halide lamps. The results showed that FL seedlings were less attractive to the whiteflies and had higher chlorophyll content and thicker leaves than ML seedlings.
Researchers at Vanderbilt University discovered that parathyroid glands emit a unique fluorescent signature in the near-infrared region, which can be used to identify them during endocrine surgery. This innovation has the potential to reduce the risk of damage to these tiny organs and their life-long effects on patients' health.
A new FRET-based sensor has been developed for real-time imaging of intracellular redox dynamics, allowing for the quantification of redox state. The sensor's dynamic range is improved, enabling better discrimination between redox states in complex biological specimens.
A new near-infrared fluorescence agent has been developed to detect deep vein thrombosis, a potentially deadly cardiovascular disease. The agent uses a biomarker that targets fibrin, a protein involved in blood clot formation, and has shown high-resolution imaging capabilities in phase II clinical trials.
Scientists from NASA's Goddard Space Flight Center have produced groundbreaking global maps of land plant fluorescence, providing a more direct window into the inner workings of photosynthesis. The maps show sharp contrasts in plant fluorescence between seasons and demonstrate the feasibility of measuring fluorescence from space.
A team of MIT chemical engineers has created a new detector that can pick up a single molecule of an explosive such as TNT, surpassing the sensitivity of existing explosives detectors. The sensor uses protein fragments to recognize nitro-aromatic compounds and can identify unique 'fingerprints' for different explosives.
Mark Bates has been awarded the GE & Science Prize for Young Life Scientists for his novel research on high-resolution imaging of biological cells and tissues. His technique, known as stochastic optical reconstruction microscopy, enables researchers to see previously hidden aspects of life with unprecedented detail.
Boston University School of Medicine researchers are developing a portable fluorescent lamp to produce vitamin D in patients with fat malabsorption syndromes. The study aims to determine the effectiveness of this device in increasing blood levels of 25-hydroxyvitamin D, with initial results expected in the spring of 2011.
Researchers developed a novel fluorescence anisotropy method to study large protein complexes in real time in live cells. The technique resolves the state of order or disorder of individual protein domains within these complexes, providing new insights into their dynamics and function.
Researchers from Helmholtz-Zentrum Berlin für Materialien und Energie (HZB) used X-ray absorption spectroscopy to observe electron transfer in biochemical substances. They discovered a 'dark channel' where excited electrons remain longer, preventing fluorescent light emission.
Researchers replaced hydrogen with deuterium in fluorescent probes to increase stability and detect smaller concentrations of reactive oxygen species. The new probes showed improved detection ability and reduced degradation by air and light, making them more accurate for imaging and analysis.
Researchers develop fluoromodules, dye-protein complexes that provide alternatives to GFP with a wider selection of colors and increased photostability. This technology enables real-time monitoring of biological activities in living cells.
The team created fluorescence quenching microscopy (FQM) to image graphene, which overcomes previous limitations in seeing these materials. FQM can be used on a variety of surfaces and requires minimal equipment, making it a promising method for quality control and research.
Scientists have recorded live vesicle fusion on the nano-scale using Fluorescence Resonance Energy Transfer (FRET). This breakthrough allows for real-time measurement of vesicle shape and properties, opening up new avenues for understanding neurological and infectious diseases.
Researchers developed a cell phone microscope, CellScope, that captures color images of malaria parasites and tuberculosis bacteria labeled with fluorescent markers. The system uses compact microscope lenses attached to a cell phone and achieves a spatial resolution of 1.2 micrometers, comparable to standard light microscopes.
Researchers have analyzed ocean plant health using a NASA satellite, detecting red light emitted by phytoplankton and assessing their productivity. The findings provide insights into the impact of climate change on ocean ecosystems and can help track long-term trends.
Scientists at the University of California, San Diego, have developed a new class of infrared-fluorescent proteins (IFPs) that can be expressed in mammalian cells. These proteins are suitable for whole-body imaging in small animals and may provide a prototype for future studies in animal models.
Researchers at Vanderbilt University have developed the world's smallest periscope, allowing for multi-vantage-point imaging of cells and micro-organisms. This technology enables scientists to study dynamic processes within cells in three dimensions, providing a high resolution form of microscopy.
A Yale University study finds that compact fluorescent lighting can increase mercury emissions in certain countries and US states, offsetting energy conservation gains. The switch to CFLs may reduce emissions in some areas, such as Estonia and China, but increase them in others, like South America and parts of Europe.
Research published in BMC Ecology reveals at least 32 reef fish species exhibiting red fluorescence, a previously unknown signaling mechanism. The authors speculate that this phenomenon may serve as a private communication system among fish, allowing for attraction and presence detection.
Researchers at Scripps Research Institute have discovered the mechanism behind the bright blue glow of fluorescent monoclonal antibodies, which could lead to the development of novel biosensors. The study found that a specific charge recombination between an electron hole and stilbene creates this effect.
A new technique called Fluorescence Diffuse Optical Tomography has been developed to image breast cancer in patients with high contrast. The method uses fluorophore molecules that re-radiate fluorescent light, providing richer information about tumor physiology.
Scientists at Vanderbilt University have overcome a major obstacle in producing fluorescent nanotubes, which can be used as contrast agents in cells and tissues. The breakthrough allows for the creation of trillions of nanotubes with high quantum efficiency, making them suitable for medical applications such as anti-cancer treatments.
Researchers at the University of Illinois have developed microcavity plasma lamps that produce bright light with high efficiency, surpassing traditional incandescent and fluorescent lighting. The panels are lightweight, thin, and can be packed into a single panel containing over 250,000 individual lamps.
Researchers at UC Davis have created luminescent, magnetic nanoparticles that can be used for tests of environmental pollution and contamination in food products. The particles can also be labeled with antibodies or DNA for genetic analysis, and have the potential to revolutionize medical diagnostics.
Researchers at Weizmann Institute create ultra-miniaturized keypad locking mechanism using fluorescent probes and iron ions. They achieve distinguishable outputs by controlling the logic gate within a reaction time frame.