Articles tagged with Optical Microscopy
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new scanning microscopy technique, SPIM, combines high spatial resolution with sensitivity to subtle electrical activity, enabling the visualization of both electronic and physical patterns in devices. The method has been successfully validated by comparing its images with atomic force microscopy scans.
A new 'superlens' has been integrated into a microscope to visualize two-dimensional objects, such as holes in gold films. This innovation increases the resolution beyond the wavelength of light, allowing for previously impossible imaging of ultra-small objects.
A new light microscope allows scientists to peer deep inside cells and study protein organization at a molecular level. This technology, called photoactivated localization microscopy (PALM), has the potential to unlock secrets of intracellular dynamics and provide new insights into cellular structures and proteins.
A new type of microscopy developed by Xiaowei Zhuang at Harvard University resolves objects as small as 20 nanometers, enabling the first ultra-resolution imaging of living biomolecules and cells. The technique, called stochastic optical reconstruction microscopy, uses glowing molecules to create high-resolution images in real-time.
Scientists have developed a new light microscope that can image cellular proteins with near-molecular resolution, surpassing conventional optical microscopes. This technique, called photoactivated localization microscopy (PALM), allows researchers to discriminate molecules separated by as little as two to 25 nanometers apart.
Researchers at Rice University have developed a method to visualize individual carbon nanotubes using standard optical microscopes and fluorescent dyes. The technique reveals the harmonic bending of nanotubes in liquids, providing insights into their behavior and potential applications in life sciences.
Scientists have visualized individual synaptic vesicles and proteins using Stimulated Emission Depletion (STED) microscopy, resolving the diffraction barrier. They found that synaptotagmin molecules remain together after fusion, enabling efficient neurotransmitter release.
A new nanoparticle sensor developed at the University of Rochester can detect individual flu viruses and particles, setting a high bar for detection techniques. Meanwhile, researchers from the University of Twente have found that thin grooves with sharp edges can speed up drying even in humid conditions.
Gold bowties may allow for the production of detailed images of proteins, DNA molecules, and synthetic nano-objects. The device amplifies near-infrared light into a concentrated speck of light, improving resolution by a factor of 10 compared to conventional microscopes.
Researchers at NIST found a significant difference between white light interferometric microscopes and phase shifting interferometers in measuring surface roughness, with discrepancies peaking at 100 nanometers. The study evaluated five instruments from three vendors and compared them to stylus profiling instruments.
Researchers at Max Planck Institute in Germany have developed Stimulated Emission Depletion (STED) microscopy, enabling resolutions of up to 16nm with conventional optics. This breakthrough surpasses the long-held resolution limit imposed by Abbe's law.
Researchers at NIST develop a novel optical imaging technique that uses structured illumination to reveal details as small as 40 nanometers. This breakthrough could transform chip-making and other industries by enabling the creation of nanometer-scale features.
The new SPIM microscope allows scientists to study live systems from multiple angles in real conditions, with minimal disruption. This enables the capture of high-quality images that would have been impossible with traditional microscopes.
Researchers developed a novel imaging process using neutrons, providing better resolution and penetration than visible light. The microscope has potential applications in biology, particularly with samples containing hydrogen.
PNNL scientists have found a new way to see beyond the 'diffraction limit' of optical microscopes, revealing the structure of DNA molecules. By combining FLIM with AFM techniques, they've produced sharp images of DNA and nanobeads.
The University of Toronto has developed technology using laser-sensitive dyes to foil document fraud, providing high data encryption and relatively low-cost production. This innovative approach could offer a speedy alternative to current security checks, enabling authorities to verify documents more efficiently.
Researchers at CU-Boulder created more efficient 'soft' x-ray light in the water-window region using a femtosecond laser, making it possible to build compact microscopes for biological imaging. This advance could visualize processes within living cells and understand how pharmaceuticals function.
Scientists have found that Bacillus spore size changes with environmental conditions, potentially allowing for rapid detection of anthrax. The discovery could enable a test to identify anthrax spores in seconds to minutes.
Researchers have developed the STED-4Pi-Microcope, which uses stimulated emission to narrow the focal spot of the fluorescence microscope, allowing for resolutions below 50 nm. This technique enables the imaging of features on a molecular level, advancing biological and medical research.
Researchers at the University of Michigan developed a new technique combining coherent nonlinear optical spectroscopy and near-field microscopy to detect quantum coherence in extended structures. This breakthrough enables sub-wavelength resolution, bringing nanotechnology closer to sophisticated devices.
Scientists at Max Planck Institute break Abbe's diffraction limit in focusing light microscopes using two laser beams and stimulated emission. The new microscope achieves sub-Abbe resolution, enabling imaging of intact transparent specimens in three dimensions.