Articles tagged with Optical Microscopy
Researchers tested two portable handheld microscopes and found they could rule in infections, but the CellScope missed low-burden infections. The devices were effective in rural settings after minimal training of community laboratory technicians.
A novel on-chip microscope made from consumer electronics enables simultaneous measurement of nanometer-thick changes over a large volume in transparent objects. The device utilizes phase-shifting interferometry and offers unprecedented field-of-view and depth-of-field capabilities, making it suitable for point-of-care applications.
Scientists used X-rays to discover the microscopic structures on butterfly wings reflect light, creating brilliant colors. Researchers found photonic crystals with tiny crystal irregularities that enhance light-scattering properties.
Chinese researchers have developed a new in situ transmission electron microscopy (TEM) technique that offers powerful functionality to understand atomic-scale structure and its correlation with physical and chemical properties. The technique has potential applications in smart windows, energy management, and environmental protection.
Researchers at Colorado State University have developed a technique to simultaneously image with multiphoton fluorescence and second-harmonic generation, achieving nanoscale resolution. This breakthrough enables the observation of previously inaccessible structures in living tissue, opening up new avenues for biological research.
Researchers at ORNL have developed a new method that provides unprecedented detail on energy flow in nanometer scale, enabling the improvement of solar cells' performance. The technique uses femtosecond transient absorption microscopy to extract images with single-pixel precision.
Researchers at CU-Boulder have developed an ultrafast optical microscope that captures real-time, slow-motion movies of light interacting with electrons in nanomaterials. The technique enables the visualization of matter on its natural time and length scale.
A team at HZB has developed an alternative method for representing microstructures in polycrystalline materials, utilizing Raman microspectroscopy. This non-invasive technique allows for orientation distribution mapping without specimen preparation, enabling analysis under ambient conditions.
Researchers have developed a new method to calibrate high-tech microscopes, enabling the tracking of single molecules in 3D at the nanoscale. This breakthrough has exciting implications for understanding key biological processes such as signaling, cell division, and neuron communication.
A new hybrid optical microscope/mass spectrometry-based imaging system developed at ORNL provides sub-micron resolution for chemical analysis and differentiates between polymers and cells. The technology enhances understanding of material interactions, drug transport, disease progression, and response to treatment.
Researchers at Einstein and Berkeley will develop new instruments to image genes and proteins in living cells, enabling visualization of gene regulation processes. The grant aims to create powerful microscopes and fluorescent probes to reveal mechanisms controlling gene expression.
The IsoView light sheet microscope produces high-resolution images of entire organisms in all three dimensions at sub-second temporal resolution and sub-cellular spatial resolution. This breakthrough enables scientists to monitor brain activity, track cell movement, and study developmental processes with unprecedented clarity.
Researchers at EPFL have created a groundbreaking DNA stain called SiR-Hoechst, which enables the safe imaging of living cells for extended periods. This innovation allows biologists to track biological processes such as cell division in real-time, paving the way for further breakthroughs in bioimaging.
Researchers developed a novel approach using liquid crystals to detect neuro-degenerative diseases by detecting the protein fibers implicated in their development. The system shows extremely high sensitivity and could enable earlier detection at a lower cost.
Researchers have imaged ultraslow pulse propagation and backward propagating waves in deep subwavelength-scale thick slabs of boron nitride, a natural hyperbolic material. The study provides insights into the behavior of light inside these materials, laying the foundations for future nanophotonic devices.
A team of researchers has developed a novel optical technique to resolve individual components of spindle pole body (SPB) duplication in living yeast cells, uncovering surprising facts about this nanoscale process. The study reveals that SPB duplication begins near the end of mitosis and forms structures not previously seen.
Researchers at the Howard Hughes Medical Institute's Janelia Research Campus have developed new imaging techniques that dramatically improve spatial resolution in living cells. The new methods offer extraordinary visual detail of structures inside cells with unprecedented clarity and speed.
Researchers at University of Illinois develop a data-based method to diagnose breast cancer using spatial light interference microscopy, promising fast and accurate results. The technique uses quantitative imaging parameters to analyze breast tissue lesions, overcoming limitations of manual inspection.
A new technology, SR-STORM, enables high-resolution imaging of multiple components and local chemical environments inside a cell. It allows scientists to examine cell structures and study diseases using unprecedented spectral and spatial resolution.
Scientists at HZDR and TU Dresden create compact camera that enables precise filming of dynamic processes at the nanometer scale. The instrument combines advantages of two methods, allowing high spatial and temporal resolution.
Scientists developed a technique to enhance nanoparticle signals using an optical microcavity, achieving near fundamental diffraction limit resolution. This enables the study of individual nanoparticles' optical properties, promising potential breakthroughs in biology, chemistry, and nanoscience.
Researchers at the Niels Bohr Institute have discovered a way to design nanowires for LEDs that use less energy and provide better light. By using X-ray microscopy, they can pinpoint the optimal structure of these tiny wires, leading to more efficient core/shell designs.
Researchers have developed a new microscope technique using holographic images and machine-learning software to identify bacterial species at the single bacterium level. The approach has shown high accuracy in distinguishing between pathogenic and non-pathogenic bacteria, promising to reduce treatment time and improve patient outcomes.
Researchers at Berkeley Lab develop CLAIRE, a technique for noninvasive nanoscale imaging of soft matter. This allows for high-resolution observation of dynamics behind nano-sized components in biomolecules, accelerating the development of technologies such as artificial photosynthesis and photovoltaic cells.
A team of MIT physicists has developed a laser-based technique to trap and freeze fermions in place, allowing for the simultaneous imaging of over 95% of potassium gas fermions. This breakthrough enhances our understanding of fermion behavior, particularly that of electrons.
Researchers at Texas A&M University demonstrate a bright, speckle-free strobe light source using random Raman lasing emission, enabling rapid imaging of microscopic forms of life. The new laser-like light source has a low level of spatial coherence and can produce high-speed images with improved quality.
Researchers developed an optical sectioning–3D reconstruction method using compound fluorescence light microscopes to image plant cells without damaging them. This approach allows for bulk processing of samples, clear imaging months after collection, and higher resolution than SEM.
KAIST researchers create a novel technique for precisely tracking the 3D positions of optically trapped particles with complicated geometry. The Optical Diffraction Tomography (ODT) method measures 3D images in high speed, enabling the visualization and analysis of particles in various fields.
Researchers have developed a new approach to sharpen nanoscale microscopy by precisely determining the light source's location, overcoming diffraction limit challenges. This innovation enables super-resolution imaging with accuracy, correcting for image-dipole distortions and improving spatial resolution.
A new compound based on rare earth ions has been developed to measure oxygen concentrations in living tissue with high precision. The compound works by emitting coloured light that varies in colour with the amount of oxygen present, making it possible to measure oxygen using optical microscopes already present in hospitals.
NYU's Materials Research Science and Engineering Center (MRSEC) received a six-year, $14.4 million NSF grant to expand its research and exploration of fundamental organizing principles of matter. The Center aims to create new materials with unique properties and advance technology sectors.
Researchers from Ohio State University and the University of Georgia collaborate to visualize cellular processes at a nanometer scale. The QSTORM project aims to enhance microscopy resolution for sub-cellular imaging, enabling scientists to make molecular movies of muscle contraction.
Researchers used microscopic fossils to date sedimentary layers and shed light on the origin of the Canary Islands. The study supports the mantle plume model, suggesting oceanic volcanoes formed from an anomalously hot plume of molten rock from the Earth's mantle.
Researchers discover cluttered jumble of randomly oriented nanocrystallites at interface, impeding charge-carrier mobility and device performance. A novel microscopy technique reveals the role of solution-processing methods in creating optimal film structures.
Researchers from UCLA have created a device that can accurately detect cancer and cell abnormalities like pathology lab microscopes. The lens-free microscope uses holograms to create 3D images, making it easier to spot any issues.
The new lattice light sheet microscope collects high-resolution images rapidly, minimizing damage to cells. It enables biologists to visualize the three-dimensional activity of molecules, cells, and embryos in fine detail.
Scientists at USC have developed CALM technology, allowing for high-resolution imaging of single molecules in living animals. The technique revealed that dystrophin regulates calcium channel fluctuations in muscle cells, leading to impaired muscle activity in muscular dystrophy patients.
Researchers at Berkeley Lab set a new record for X-ray microscopy, achieving resolutions of five nanometers using soft X-rays and ptychography. This breakthrough enables the visualization of chemical phase transformations and mechanical consequences at the nanoscale.
Scientists are developing new technologies at the atomic scale to create ultra-low-power electronics. This breakthrough has the potential to revolutionize the electronic industry, enabling smaller, more efficient devices that can be powered by longer-lasting batteries.
The HZB team has developed novel 3D X-ray optics, enabling sharper imaging with improved resolution. The new optics capture more light and can be stacked on top of each other to achieve even better results.
Scientists have developed a new imaging system that reveals neural activity throughout the brains of living animals in 3-D. The technique allows for simultaneous imaging of every neuron in the worm Caenorhabditis elegans and the entire brain of a zebrafish larva, providing a more complete picture of nervous system activity.
Researchers have developed a new process to create high-quality lenses at a low cost, making them suitable for various applications including disease detection, scientific research, and education. The lenses were created using a simple method involving the hanging and curing of droplets of transparent silicone polymer.
The Biotechnology and Biological Sciences Research Council (BBSRC) is investing £10M in advanced scientific research instruments. This funding supports world-leading research in various fields, including plant biology, microscopy, and protein interactions.
Researchers at Berkeley Lab have developed a technique to image individual carbon nanotubes, allowing for the characterization of their electronic and optical properties. This breakthrough enables the identification of specific species of nanotubes in functional devices, crucial for advancing nanotube technology.
Researchers have developed two new microscopes that capture fast-moving cells in 3-D and reduce light exposure to preserve cell health. The iSIM microscope enables real-time super resolution imaging of small structures at high speed.
Researchers have developed a new Spinning Disk Statistical Imaging (SDSI) system that allows for deeper imaging of cellular structures, including viruses and parts of the nucleus. The technique combines super-resolution microscopy with fluorescent probes to produce high-speed focused images.
Researchers at MIT have developed a new concept for a microscope that uses neutrons to create high-resolution images, enabling the probing of internal structures in metal objects and biological materials. The device could improve existing neutron imaging systems by a factor of 50, allowing for sharper images and smaller instruments.
A Harvard team has developed a new microscopy method using DNA nanotechnology to overcome the diffraction limit and visualize tiny molecules in cells. The method, called DNA-PAINT, creates 'imager strands' that bind to target molecules, making them appear to blink and enabling sharper images than traditional methods.
Scientists at Queen Mary University of London developed a new technique to measure electrical activity in synapses, enabling three-dimensional visualisation of neuronal networks. This breakthrough opens a new window into understanding brain function at the nanometre scale.
Researchers at the University of Warwick have developed a way to control the speed and direction of motion of microscopic structures in water using chemotaxis. By adding a chemical catalyst, they can propel matchstick particles towards a specific location, demonstrating a versatile method for directing colloidal motion.
Arizona State University researchers have received a $1.6 million grant to develop advanced microscopy methods that can capture molecular-scale phenomena in living systems. The technique, called plasmonic resonance, allows for the imaging of proteins and other molecules within cells with enhanced contrast and temporal resolution.
Researchers create a method to convert conventional microscopes into high-resolution imaging systems that outperform standard microscopes. The new system combines the field-of-view advantage of a 2X lens with the resolution advantage of a 20X lens, producing images with 100 times more information.
A new microscopy technique called Through-Focus Scanning Optical Microscopy (TSOM) can detect tiny differences in the three-dimensional shapes of circuit components. This enables the semiconductor industry to improve chips for the next decade or more by measuring features as small as 10 nanometers across.
A new microscopy technique developed by NIST researchers uses cathodoluminescence to image nanoscale features with high resolution. The technique combines the benefits of optical and scanning electron microscopes, evading traditional limitations such as diffraction and sample preparation requirements.
Visikol, a polychlorinated alcohol mixture, effectively clears organisms for viewing under microscopes without the need for federal regulation. Developed as a replacement for chloral hydrate, it offers safety and cost benefits while maintaining high-quality microscopic images.
Researchers at Purdue University have developed a new super-resolution optical microscopy technique that can image synthetic nanostructures and molecules without the need for fluorescent dyes. The technique, called saturated transient absorption microscopy (STAM), uses a trio of laser beams to selectively illuminate molecules, allowing...
Researchers at Berkeley Lab's Advanced Light Source are transforming X-ray microscopy into a widely available form of high-resolution imaging. State-of-the-art instruments can create three-dimensional images with elemental and/or chemical sensitivity, allowing for unprecedented insights into biological systems.
Researchers used a super-resolution microscope to study protein distribution in human T-cells, revealing the dynamic opening and closing process of kinase molecules. This discovery could provide insights into immune disorders and cancer by understanding how signaling processes are controlled.
Researchers from China have devised a universal method using just an optical microscope to measure graphene and other two-dimensional materials' thickness. The technique exploits the reflected light's red, green, and blue components, increasing contrast with sample thickness.
A team of scientists has developed integrated arrays of optical vortex beams on a silicon chip, which can be used to transmit multiple streams of information. This breakthrough could enable the creation of compact and high-density devices for applications such as sensing and microscopic particle manipulation.