Scientists have characterized lipid nanoparticles' internal shape and structure, which correlates with how well they deliver therapeutic cargo. The research provides a blueprint for engineering more effective RNA therapies by matching LNP designs to specific therapies and tissues.
SourceUniversity of Pennsylvania School of Engineering and Applied Science·JournalNature Biotechnology·TypeExperimental study·DateOct 23, 2025
Regional mesylate anticoagulation in centrifugation artificial liver support systems is safe for liver failure patients at risk of bleeding. Adjusting the mesylate dose based on pre-R and pre-MA enhances safety.
SourceXia & He Publishing Inc.·JournalJournal of Clinical and Translational Pathology·DateApr 10, 2025
Researchers developed a microfluidic device to alleviate limitations of conventional blood-filtering machines used in treating hyperleukocytosis in children. The new device separates blood cells by size without platelet loss or adverse effects, enabling safe leukapheresis procedures.
SourceUniversity of Houston·JournalNature Communications·DateMar 19, 2025
Researchers at NTU Singapore have created a chip that can directly isolate blood plasma from a tube of blood in just 30 minutes, removing over 99.9% of blood cells and platelets. The device, called ExoArc, enables high-quality plasma for disease screening and research, improving diagnosis accuracy and reducing waiting times.
SourceNanyang Technological University·JournalACS Nano·TypeRandomized controlled/clinical trial·DateMar 21, 2024
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new method, EPISENS-S, has been developed to measure SARS-CoV-2 in wastewater with high sensitivity. This allows for the estimation of COVID-19 prevalence, including asymptomatic cases. The method was found to be approximately 100 times more sensitive than existing methods.
SourceHokkaido University·JournalScience of The Total Environment·TypeExperimental study·DateSep 28, 2022
A new method has been developed using a microchip device that sorts sperm based on their swimming potential, allowing for faster and cheaper selection of viable sperm. This technology may improve IVF success rates, especially in women under 35 who have low chances of successful fertilization.
Researchers studied knotted steel chains in a viscous fluid, reproducing Kelvin's vortex atoms. The chains formed stable, toroidal structures with intertwined loops that swirled around each other.
SourceUniversity of Warsaw, Faculty of Physics·JournalPhysical Review Letters·DateSep 25, 2018