Affinity Chromatography

In a preclinical study, a new jararaca antivenom serum was three times more effective than the standard one

Researchers developed a new, three times more effective version of the antibothropic serum used to treat snake venom poisoning. The improved serum had increased neutralizing antibodies and fewer proteins associated with side effects, resulting in greater potency and reduced risk of adverse reactions.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Proteome Research·DateApr 15, 2025

A method to purify proteins with light: Gentler and more efficient than previous procedures

Researchers at TUM have developed a novel method to purify proteins using short-wave UV light, eliminating the need for chemical reagents. The 'Azo-tag' system changes shape under light exposure, allowing for targeted purification of proteins in a more efficient and gentler manner.

SourceTechnical University of Munich (TUM)·JournalNature Communications·TypeExperimental study·DateMar 5, 2025

Clearing the way for faster and more cost-effective separations

Researchers at Case Western Reserve University found that manufactured separation materials don't function as intended due to blocked pores, leading to inefficient and expensive separations. Single-molecule microscopy technique revealed the behavior of individual molecules, allowing for predictive performance and design improvements.

SourceCase Western Reserve University·JournalScience Advances·DateFeb 14, 2025

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

High-throughput genotyping, protein purification featured in Cold Spring Harbor Protocols

The article features laboratory methods for high-throughput genotyping, including single-nucleotide polymorphism (SNP) genotyping and next-generation sequencing. The tandem affinity purification (TAP) procedure is also presented as a method for protein purification.

SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateNov 2, 2009