Articles tagged with Publishing Industry
Researchers found that NSD2 helps maintain MM cell identity by reorganizing DNA and influencing gene activity. This discovery could shape future treatment approaches for patients with t(4;14) myeloma.
Researchers discovered senolytics can target Alzheimer's disease-associated brain enzymes AChE and BChE without affecting healthy ones. This selective approach may lead to safer treatments that improve memory and reduce inflammation in older adults.
All articles with at least one author based in Africa can now be submitted to the platform and will no longer require funding from a partnering research funder. This expansion aims to increase publication efficiency and improve the experience of African authors, while promoting the rapid sharing and discovery of high-quality research.
Researchers at Cornell University discovered that the FGR protein can induce cell differentiation in leukemia cells similar to retinoic acid treatment. The presence of FGR alone was enough to make these cells mature, producing well-known markers of maturation and expressing inhibitor of the cell cycle p27.
The MIT Press has funded the open publication of 320 books through its Direct to Open framework, which shifts from market-based purchase models to collaborative library-supported open access. This approach has shown significant usage and citation increases for Humanities and STEAM books, with a notable impact on global readership.
A new review highlights how breast cancer cells change their communication and growth patterns, helping tumors survive, spread, and resist treatment. The review explores disrupted signaling pathways, including PI3K/Akt/mTOR and RAS/RAF/MEK/ERK, which can promote tumor progression and resistance to treatment.
A new study found that treating aged mice with montelukast improved retinal health by reducing inflammation and boosting proteasome activity. This approach may offer a promising new way to slow age-related vision loss and protect eye health in older adults.
The company will use AI translation tools to publish books in multiple languages, making them accessible to a broader audience. This initiative aims to promote better understanding between cultures and accelerate awareness of knowledge required to meet today's challenges.
Scientists at POSTECH and University of Montpellier successfully synthesized wafer-scale hexagonal boron nitride (hBN) with an AA-stacking configuration using metal-organic chemical vapor deposition (MOCVD). This achievement introduces a novel route for precise stacking control in van der Waals materials.
This study found that aging impacts the gut microbiome composition and metabolites differently in male and female rats, influenced by biological sex and mitochondrial DNA. The researchers analyzed fecal samples from genetically diverse rats to assess bacterial changes with age, revealing more significant shifts in females.
Breast cancer survivors experience accelerated aging due to detrimental effects of BC and its treatments, particularly systemic therapies. The study highlights the need for ongoing monitoring and potential strategies to slow down aging in cancer survivors.
Impact Journals is proud to exhibit at the AACR Annual Meeting 2025, featuring its esteemed journals Aging-US, Oncotarget, Oncoscience, and Genes & Cancer. The meeting highlights significant advancements in cancer research, aligning with Impact Journals' mission to disseminate impactful scientific research.
Recent research suggests that some invasive cancers diagnosed in early-stage breast cancer may not need immediate surgery, highlighting the importance of more precise screening methods for DCIS. The COMET trial found that at least half of invasive breast cancers take years to progress or may never progress at all.
Research from the Long Life Family Study found individuals from long-lived families have significantly better vascular health than the general population. The study identified key risk factors and four genomic regions linked to PAD risk, providing novel insight into underlying mechanisms.
Genetic changes triggered by environmental factors like pollution, diet, and stress can increase cancer risk. Nearly everyone is exposed to cancer risk factors daily, highlighting the need for public awareness and policy action to reduce exposure.
Researchers found that PRP treatment increased gene expression related to metabolism, cell survival, and communication between cells in cumulus cells. This suggests that PRP may help support egg development and fertility in women with poor ovarian response.
Daniel G. Graham, author of 'Ethical Hacking', has contributed expertise to the new edition of 'Metasploit: The Penetration Tester's Guide'. This comprehensive resource covers key topics such as penetration testing in cloud environments and advanced evasion techniques.
Researchers have discovered several novel downstream p53 targets that could lead to improved cancer therapies. The study highlights the critical role of p53 in preventing cancer and identifies two new genes, ALDH3A1 and NECTIN4, as potential targets for cancer treatment.
A new test called EpiAgePublic estimates biological age using only three DNA sites in the ELOVL2 gene, simplifying traditional methods while maintaining accuracy. The study found that EpiAgePublic accurately tracks aging patterns and can identify factors accelerating the aging process.
A research team at POSTECH developed a synthesis method that precisely controls the size and shape of perovskite nanocrystals using liquid crystalline antisolvents. The method produces uniformly sized particles without additional purification processes, accelerating commercialization of optoelectronic devices.
A study found that pro-inflammatory molecules contribute to benign prostatic hyperplasia (BPH) in aging men, especially those with metabolic syndrome. Men with BPH had higher levels of pro-inflammatory markers and lower anti-inflammatory substances, suggesting a link between inflammation and prostate conditions.
A report by University of Cambridge experts highlights the risks of unregulated AI use on UK's thriving creative sector. The researchers argue that forcing creatives to 'opt out' of AI training could compromise their livelihoods, particularly those just starting out.
A rare case of adenomyosis in an 81-year-old postmenopausal woman closely resembles invasive endometrial cancer, emphasizing the challenges of diagnosing this condition. Further studies are needed to refine diagnostic protocols and determine risk factors for postmenopausal patients.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
Osteosarcoma cells often have extra copies of the SETDB1 gene, making the cancer more aggressive and harder to treat. Blocking SETDB1 may help the immune system recognize and attack osteosarcoma cells, offering a promising new way to treat this type of bone cancer.
A rare case report highlights the association between systemic mastocytosis and severe osteoporosis in a young adult patient, emphasizing the importance of early diagnosis and consideration of SM as an underlying cause. The study aims to raise awareness about this underrecognized condition and its potential impact on bone health.
A study found that DNA methylation clocks used in forensic science and epigenetics are less reliable when applied to non-blood tissues, such as lungs, colon, and kidneys. The researchers suggest that organ-specific epigenetic clocks may be needed to improve biological age prediction.
A new research paper found that physical activity (PA) is associated with better sleep quality in older adults during social isolation. Reduced levels of PA had a negative association with the quality of sleep in four studies, while one study found improved sleep patterns among active individuals.
A new genetic mutation, RUFY1-RET fusion, was discovered in a patient with stage IV CD-74-ROS1 fusion NSCLC who developed resistance to lorlatinib. The finding highlights the importance of ongoing genetic testing to guide therapy decisions.
A large study found pregnant women with cervical cancer face higher health risks during pregnancy and childbirth, including premature birth and cesarean sections. However, the babies' health is largely unaffected, with no significant differences in birth defects or stillbirths.
A study found clear differences in brain health between Hispanic and non-Hispanic White older adults, with Hispanic participants scoring lower on tests of memory, attention, and problem-solving despite similar mental health. Researchers emphasize the importance of considering social, economic, and cultural factors when developing progr...
Researchers discovered that a topical ABT-263 treatment effectively reduces aged skin senescence markers, priming the skin for improved subsequent wound healing. The treatment also triggered inflammation, which surprisingly helped the healing process by 'waking up' the skin's repair systems.
A team of researchers has developed a novel model of the Blood-Brain Barrier, which mimics the complex structure of cerebral blood vessels. This breakthrough enables scientists to study neuroinflammation and develop new therapeutic strategies for Alzheimer's disease and other neurodegenerative disorders.
Researchers found a genetic change, pR552*, that could give the RB1 gene a new function leading to cancer growth. This challenges the common belief that both copies of the RB1 gene must be damaged for cancer to develop.
Aging cats with chronic kidney disease (CKD) have lower levels of key kidney transporter genes, leading to impaired waste removal. Monitoring these transporters and toxin buildup may help detect CKD early and improve treatment options.
Researchers tracked cfDNA levels before, during, and after colorectal cancer surgery, revealing significant increases associated with age, comorbidities, and surgical manipulation. The study suggests that cfDNA could serve as a non-invasive biomarker to monitor patient outcomes and evaluate surgical effectiveness.
A report by Tel Aviv University highlights the establishment of new museums in Muslim countries, including Indonesia, Dubai, and Albania, which showcase the Holocaust and heroism. These museums provide a counter-narrative to antisemitic propaganda and promote education and awareness about the Holocaust.
Researchers found that pomalidomide enhances key immune cells, such as T cells and natural killer cells, which helps the body recognize and destroy cancer cells. This leads to improved immune profiles in patients with myeloma, resulting in longer progression-free survival periods.
Researchers explore HER2-low breast cancer, a new clinical subtype that benefits from novel treatments and personalized care. Current testing methods are not always accurate, calling for better detection methods to correctly identify patients who can benefit from these new therapies.
Researchers discovered that removing arginase-II gene can slow down muscle aging in mice, leading to improved muscle health and reduced inflammation. This finding suggests targeting the Arg-II gene could help maintain muscle strength and mobility in older adults.
A new study published in Oncotarget discovered an anti-correlation between PD-1 and KLRG1 expression in human tumor infiltrating CD8 T cells. This finding suggests the potential for combination therapy to enhance cancer treatment by targeting both markers simultaneously, which could lead to more significant and long-lasting benefits.
A study found that a simple blood test could predict breast cancer risk in older women by measuring biological aging via DNA methylation changes. Lifestyle factors, such as obesity and hormone replacement therapy, also influenced epigenetic aging and breast cancer risk.
A new study published in Aging found that pioglitazone reduced the frequency of skin ulcers in Werner syndrome patients. The research suggests that pioglitazone's anti-inflammatory properties may help wounds heal faster and prevent ulcers from forming.
Dr. Blagosklonny's work introduced a new theory and promoted the use of rapamycin to slow aging and extend healthy life by targeting the mTOR pathway, leading to improved immune responses, heart protection, and potential cancer prevention.
Researchers identified early cellular changes associated with Mandibular Hypoplasia, Deafness, Progeroid Features, and Lipodystrophy (MDPL) syndrome, a rare genetic aging disorder. MDPL syndrome is characterized by premature aging of mesenchymal stem cells, which can form tissues like bone and fat.
A University of Houston study found that different genotypes of hemp have unique microbial communities that impact CBD production and fiber quality. The research, published in Nature, highlights the potential for microbiome diversity to inform more sustainable farming practices.
GetFTR has integrated Taylor & Francis eBooks platform, enabling researchers to access books with real-time entitlement checks. The integration directs eBook requests to the eBooks platform and journal article requests to Taylor & Francis Online.
The partnership aims to enhance publication and dissemination of eDNA research, increasing visibility and impact. Pensoft will support SeDNAs conferences and publish special issues in its Metabarcoding and Metagenomics journal.
Researchers found that brown adipose tissue enhances exercise endurance and supports healthy aging by improving blood circulation and reducing cellular stress. The study suggests that treatments mimicking BAT's benefits could lead to innovative therapies for improved energy levels and heart health.
The accumulation of nuclear lipid droplets (nLDs) is linked to metabolic conditions such as fatty liver disease, obesity-related disorders, and premature aging. Lifestyle interventions like caloric restriction can reduce nLD buildup, suggesting a potential therapeutic target for slowing cellular aging.
Dr. Marco Demaria joins Aging-US as Editor-in-Chief with expertise in cellular senescence and aging research. He aims to develop new therapeutic approaches to mitigate age-related diseases.
Chung-Ang University researchers have developed self-powered tactile sensors for robotics and wearables by introducing novel manufacturing strategies for piezoelectric and triboelectric sensors. These advancements aim to create high-performance sensors capable of multi-modal sensing and real-time interaction.
A new study reveals that anti-defense genes near the DNA entry point enable plasmids to overcome CRISPR system, promoting genetic transfer between bacteria. This discovery could pave the way for developing tools to address antibiotic resistance and genetic manipulation methods.
A POSTECH research team developed a groundbreaking strategy to enhance LLO material durability, extending battery lifespan by up to 84.3% after 700 cycles. The breakthrough addresses capacity fading and voltage decay issues.
A new study from Tel Aviv University finds minimal environmental pollution resulting from ancient copper production in King Solomon's Mines, with pollution levels confined to smelting furnaces. Researchers also contradict previous claims of widespread industrial pollution, citing low levels of lead and other metals in soil samples.
The team developed a Synthetic Translational Coupling Element (SynTCE) that enhances the precision and integration density of genetic circuits in synthetic biology. This allows for more efficient gene circuit integration, minimizing interference between biological parts and enabling precise control over multiple genes.
A recent study published in Social Science & Medicine reveals the complexities of conducting cannabis research in Canada, where researchers face structural barriers and concerns about scientific integrity. The study suggests key solutions to increase public funding, enhance transparency, and promote independence in research.
A new study found that heat therapy positively modulates multiple physiological parameters in APP/PS1 mice, with improved memory in males and worsening effects on females. This highlights the importance of personalized treatments based on sex-specific responses to therapy.
Researchers found that soil contains antibiotic resistance genes that can be transmitted to humans, making it a pressing public health threat. The study reveals how these genes spread through the environment and highlights the importance of understanding soil ecosystems to control antibiotic resistance.
CEOs innovate based on stock recommendations and analyst feedback, which can foster explorative activities like R&D. However, many sacrifice long-term sustainability for immediate returns, incentivized by their compensation packages.