News on the use of animals, and their alternatives, in biomedical research. Covers animal models, primate studies, tissue chips, research ethics, and disease modeling.
Two new species of poisonous birds have been discovered in New Guinea's rainforest, containing a neurotoxin similar to that found in South American poison dart frogs. Genetic changes in these bird species allow them to tolerate and store the toxin in their feathers, potentially serving as a defensive mechanism.
Researchers found that bats lose their hearing in old age due to exposure to high noise levels in their colonies. The study suggests that bats may have evolved adaptations to cope with these noisy environments, which could provide insights into human age-related hearing loss.
Scientists have discovered the origin of congenital coronary fistulae, a condition where abnormal connections form between blood vessels and heart chambers. This study may help improve early diagnosis and treatment of this condition, which affects up to 0.2% of patients undergoing medical examination.
Researchers at Tel Aviv University recorded and analyzed plant sounds emitted under stress, identifying specific identifiable sounds. The study suggests that plants may communicate with other plants and animals through these sounds.
The funding will support preclinical research using genetically modified pigs, aiming to improve compatibility and reduce immune rejection in xenotransplantation. The goal is to enable human clinical trials and address the organ shortage crisis.
A study by UConn researchers found a significant improvement in shod horses, with better movement and reduced lameness scores. Shoeing with plain stamp shoes improved maximum hock angles and gait quality, indicating potential benefits for athletic performance.
A study of over 65,000 Japanese infants found that those exposed to indoor pets during fetal development or early infancy had fewer food allergies. Children exposed to indoor dogs and cats were significantly less likely to experience specific allergies, while hamster exposure unexpectedly increased the incidence of nut allergies.
A new study from the University of Exeter finds that a vegan diet rich in mycoprotein can support muscle growth during resistance training to the same extent as an omnivorous diet. The study shows comparable increases in muscle mass and strength in response to both diets.
A team of researchers from South Africa has discovered exceptional trace fossils that provide insight into the locomotion of ancient giant amphibians. The fossils, found on a rock surface once part of a tidal flat or lagoon, suggest these animals propelled themselves through water with continuous side-to-side tail motions.
Researchers have found lab-made antibodies that can strengthen the body's fight against yellow fever, a disease with no current treatment. The monoclonal antibody infusions were able to remove all signs of infection from research animals, offering potential hope for a cure.
Researchers used thermal video and image analysis to measure heart and respiration rates in exotic wildlife species in controlled settings. The study validated the accuracy of this technology for future use in wild populations, especially threatened species.
A study of bird poop reveals a unique relationship between birds and their microbiomes, which differ from those found in mammals. The researchers found that the types of bacteria present in the birds' gut microbiomes change over short time periods, rather than being tied to specific host species.
Researchers at Cornell University have discovered that female giant African pouched rats can undergo 'unusual' reproductive organ transformations. The study, published in Current Biology, explores how traits once considered fixed in adult animals may become variable under specific pressures.
A new study has confirmed that chronic THC use can negatively impact male reproductive health, including testicular function and sperm quality. Discontinuing use of THC for at least four months can partially restore these effects, providing a critical window for family planning and conception.
A University of Illinois study finds that two human-grade vegan diets provide adequate nutrition for dogs, with benefits including lower blood triglycerides and cholesterol. The research also shows positive changes in the fecal microbiome and reduced stool, indicating a potential shift towards improved gut health.
Researchers discovered that mechanical loading can exacerbate inflammation in aged muscles, hindering healing. However, combining mechanotherapy with anti-inflammatory treatment significantly improves healing in aged muscles.
Researchers developed a neural implant that restored limb function to amputees and paralysed individuals by integrating with the brain and nerve. The biohybrid device combines electronic components with reprogrammed muscle cells, preventing scar tissue formation and improving signal extraction.
A new mosquito species, Culex lactator, has been found in Florida, with thriving populations reported in three counties. Scientists are concerned about the potential for this species to transmit diseases, particularly given the lack of research on its disease risk.
Two species, South American sea lion and fur seal, are primarily involved in interactions with fisheries and aquaculture activities. The economic losses to fisheries related to sea lion depredation are low, while incidental capture and mortality of seals remain unknown.
The Cinereous Vulture has been reintroduced to Bulgaria after being extinct for 36 years. The successful re-introduction campaign, led by Green Balkans and other organizations, involved importing 72 birds from Spain and European zoos. The team recommends the aviary method and delayed release for establishing a new core population, and ...
A recent study published in Communications Biology used thermal imaging to capture the social dynamics of 'pee-shy' mice, revealing that males adjust their urine marking behavior based on their past interactions. The research provides insight into how animals manage their social signaling, a crucial aspect of their survival and evolution.
A new study has uncovered the brain's internal compass, which helps it navigate changing environments. The research found that the brain uses a mechanism called 'network gain' to reorient itself after being disoriented, allowing for rapid recovery of its sense of direction.
Researchers developed an AI tool called SILIC to identify 169 species, including 137 birds, from bird sounds in Yushan National Park. The dataset provides detailed acoustic activity patterns of wildlife across short and long temporal scales.
Researchers have shed light on the molecular mechanisms allowing beetles to absorb water rectally, a property enabling them to survive in extremely dry environments. This knowledge could be used to develop more targeted and eco-friendly methods to combat beetle species that destroy food production.
A new study found that artificial light at night increases top-down pressure on caterpillars, leading to higher mortality rates. The research used clay models of caterpillars to demonstrate the impact of light on predators in a forest ecosystem.
A study found that human-caused mortality is the leading source of death for mountain lions in California, primarily driven by conflicts with humans over livestock and collisions with vehicles. The research also suggests that human tolerance plays a crucial role in conserving large carnivores in landscapes shared with humans.
Researchers have developed a high-speed, 3D gigapixel microscope that stitches together dozens of cameras to capture life in unprecedented detail. The device enables the recording of differences in pitch and depth, allowing scientists to study zebrafish behavior and developmental biology without harming the animals.
A study by University of Utah researchers found that birds eat fewer invertebrates in coffee plantations than in forests, threatening their survival. The disturbance of ecosystems significantly impacts dietary options, leading to reduced survival and population declines.
A research review found that COVID-19 lacks canine data, fueling concerns about the risk of pet animals serving as virus reservoirs. The lack of testing has made it difficult to understand the susceptibility of dogs to the new variants.
Researchers have developed a new technique that combines real-time images with short-wave infrared light to differentiate between cancerous tumours and healthy tissue. This innovation has the potential to improve treatment outcomes for neuroblastoma patients by allowing surgeons to remove cancerous cells more precisely.
A team of researchers at Kyoto University has established a method to identify individual inbred medaka killifish by analyzing the characteristic patterns of dark spots on their heads. This identification method may contribute to biometrics for medical and drug discovery research.
New research directly measures human muscle contractile properties, revealing that extrapolating animal data to humans based on size is inaccurate. The study finds that human muscle fiber-specific tension is 24% smaller than traditionally used in small mammals.
Researchers at the University of California - Riverside have discovered a way to deactivate mosquito sperm, preventing them from swimming to or fertilizing eggs. This breakthrough could help control populations of Culex mosquitoes that transmit infectious diseases like encephalitis and West Nile Virus.
Archaeologists have discovered evidence of ritualistic belief and economic factors intertwined for Neolithic people in northwest Arabia. Excavations at a mustatil east of AlUla revealed animal offerings, human interment, and suggest repeated pilgrimages, challenging previous understandings of the region's culture.
A study led by UNSW Sydney found that Tasmanian devils in human-modified landscapes have limited diets compared to those in undisturbed environments. The researchers analyzed stable isotopes in whisker samples to determine the devils' prey, finding they fed on smaller animals and less varied food items in altered habitats.
A new study published in Current Biology found that the hippocampus and prefrontal cortex must synchronize their neural assemblies to support memory encoding, maintenance, and recall. Disruption of this synchronization leads to memory loss, presenting a viable target for therapeutic interventions.
A new University of Alberta study found that untreated moderate fever helped fish clear their bodies of infection rapidly and repaired damaged tissue. The research suggests that waiting before reaching for medications may be beneficial for humans.
Researchers found that dogs with anxiety have altered brain connectivity, particularly between the amygdala and hippocampus. The study used fMRI to characterize abnormal neural networks in anxious dogs, providing insight into anxiety disorders in both animals and humans.
Researchers at Houston Methodist discovered a way to reverse infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein. The study showed that this protein, called serum opacity factor, lowered HDL cholesterol levels by over 40% in three hours and restored fertility in the mice.
A study found that high winds increased Campylobacter prevalence in outdoor chicken farms, with 26% of individual chickens infected. Farmers are advised to consider windbreaks and monitor weather patterns to reduce exposure.
A new study reveals that whooper swans thrive in UK nature reserves, with survival rates significantly higher and population growth up to 6% annually. This could lead to a doubling of the species' wintering population in the UK by 2030.
Cambridge researchers observe Unio crassus mussels squirting water jets up to a meter away from the riverbed to increase the chances of their larvae attaching to specific host fishes. This behavior has never been seen in any other mussel species and may be crucial for the endangered species' survival.
Research at Kobe University reveals that endogenous retrovirus activation increases a fetus's susceptibility to autism, leading to differences in brain structure and behavior. The study identifies BTBR/R mice as a more accurate model of autism, exhibiting autistic-like behaviors without reduced learning ability.
Researchers at IISc found that grazing by livestock leads to lower carbon storage in soil compared to wild herbivores due to antibiotic use. Re-wilding soils and quarantining animals could help offset the damage.
Researchers at the University of California - San Diego found that honey bees use a 'waggle dance' to communicate the location of food sources, and that this behavior is improved by learning and culturally transmitted. The study demonstrates the importance of early social signal learning in non-human spatial referential communication.
Research reveals island-dwelling mammal species face higher extinction risks, with those experiencing extreme size changes being particularly endangered. Human arrival on islands multiplies the probability of extinction by 16, contributing to a 'protracted extinction event' spanning over 100,000 years.
New research from Harvard Medical School reveals that female mice display more consistent exploratory behavior despite hormonal fluctuations. This finding highlights the importance of including both sexes in neuroscience experiments to gain a deeper understanding of the brain and its functions.
Researchers found that newborn chicks prefer stimuli moving upward against gravity, even without prior experience. This innate preference suggests that animals are born with a predisposed knowledge of sensitivity to simple features guiding behavior from birth.
The Center for C. elegans Anatomy is receiving $2.6 million in funding from the NIH to expand WormAtlas, a resource for researchers studying C. elegans and other nematodes. The expansion aims to incorporate new nematode species into the atlas, enabling comparisons between C. elegans and less-studied species.
A new study highlights the importance of grassroots data collection in reducing bird-window collisions, which kill an estimated 365 million to nearly one billion birds annually. The study emphasizes the need for better data collection methods and increased funding to support citizen science efforts.
A team of scientists has developed a novel, implantable drug delivery system that can be controlled by external light sources and is absorbable by the body. This technology has promising implications for treating various medical conditions, including pain management and cancer treatment.
A study from the University of Georgia found that less than half of bald eagle nests in coastal Georgia successfully fledged at least one chick in 2022, a 30% decrease below average. The highly infectious H5N1 avian influenza virus is killing off unprecedented numbers of mating pairs of bald eagles, with the number of infected wild bir...
The University of Missouri will receive a $10 million grant from the USDA National Institute of Food and Agriculture to double cover crop seed production in the US by 2030. The project aims to educate farmers about new varieties of cover crops, examine their performance with root growth, and distribute them nationwide.
Researchers explore cellular senescence's complex relationship with growth stimulation and cell cycle arrest, revealing potential anti-aging drug targets. Understanding these mechanisms is crucial for developing new treatments for age-related diseases.
Researchers investigated how seabird flight characteristics vary among different species in response to cyclone-strength winds. Birds living in windier environments are faster fliers, while tropical species use strategies to cope with extreme events. Some albatrosses even avoid strong winds by flying into the eye of the storm.
A study by Dr. Maria M. Georgi and colleagues found that mulching times of forest meadows have a negative impact on both insect larvae and flower-visiting insects. Mulching in September was shown to protect the latter, while mulching in June had a negative effect.
Researchers discovered that woodcock tail feathers reflect up to 55% of light, 30% more than any other bird feather, due to their unique structure and arrangement. This enhanced reflectance allows them to attract attention in dimly lit environments.
A study published in PLOS ONE analyzed a Bronze Age debris deposit in Mycenae, Greece, revealing the types of animals that lived there and how they were used as a source of subsistence. The analysis of animal remains and associated artifacts provides clues to the social dynamics of ancient settlements and responses to natural disasters.
A study by the University of Exeter found that flamingos form groups based on their individual personalities, with birds of similar traits spending more time together. This complex social behavior could help improve the welfare of captive flocks and provide insights into the evolution of bird societies.
A new snake family, Micrelapidae, was identified through an international study led by Tel Aviv University researcher Prof. Shai Meiri. The family includes only three species, two in Africa and one in Israel, and diverged from the rest of the evolutionary tree about 50 million years ago.