Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study by Duke University researchers reveals that pups of dominant female meerkats, exposed to higher levels of testosterone in the womb, tend to carry more gut parasites and have weaker immune systems. Blocking a matriarch's testosterone improved the health of her pups, leading to stronger natural defenses against infection.
A new study uses hyperspectral imaging to quantify the colorful plumage of birds-of-paradise, a rare hybrid species. The research reveals that the hybrid's appearance is a precise blend of colors from its parent species, with detailed ultraviolet images capturing patches invisible to humans.
A new study suggests that chimpanzees exhibit complex behaviors involving the production of elaborate sequences, including planning and adjusting action sequences on the fly. This research provides further evidence that chimpanzees possess human-like technical flexibility.
A new study has discovered that close spatial proximity serves as an indicator of friendship in feral female buffalo, with individual personalities playing a key role. The research found that buffalo with similar social tension, vigilance, and general dominance traits tended to spend more time together.
Researchers discovered a neural mechanism that governs fish embryo hatching through the neurohormone TRH. This finding reveals that embryos are not passive but actively make life-or-death decisions, offering new insights into neurobiology and environmental adaptation.
A new gene therapy has shown promise in reversing a condition that causes significant stillbirths and premature deliveries globally. The therapy, developed by University of Florida Health researcher Helen N. Jones, successfully boosted placental function and delivered normal-weight offspring in guinea pig models.
Researchers at Tokyo University of Science have developed a new, highly selective and efficient method for synthesizing anti-cancer compounds. The innovative approach uses isopropyl magnesium bromide as a base to improve selectivity and scalability.
Researchers at Sanford Burnham Prebys found that pancreatic cancer cells rely on a specific nutrient, glutamine, to fuel their unchecked growth. The study identified two enzymes, aPKC zeta and iota, that play a regulatory role in the process of macropinocytosis, allowing cancer cells to scavenge alternative resources.
Researchers found that EZH2 inhibition boosts T-cell immunotherapies' effectiveness by making cancer cells more visible and reducing immunosuppressive regulatory T-cells. This combination therapy showed improved survival rates in mice with lymphomas, suggesting a potential new approach to treating certain cancers.
A recent study published in Nature found that mother fleas can transmit the plague to their offspring, posing a significant threat to prairie dog colonies and other rodent populations. This discovery highlights the importance of understanding the role of animals in the dissemination of the disease.
Researchers have developed a non-invasive strategy that assesses blood flow through skeletal muscle to detect early signs of sepsis. The technique, combining hyperspectral near-infrared spectroscopy and diffuse correlation spectroscopy, was tested in rodents and detected sepsis before vital organs were affected.
Researchers observed 34 male African savannah elephants in Etosha National Park, identifying five types of behavior that were consistently different between individuals. Younger males were more similar in temperament than older males, suggesting that their unique personalities develop as they age.
A new study reveals that glyphosate exposure in mice can cause lasting brain inflammation and accelerate Alzheimer's disease-like pathology, even after a significant pause from exposure. The herbicide's byproducts have been found to accumulate in brain tissue, raising serious concerns about its safety for human populations.
The American Heart Association warns hunters about the increased risk of heart attack and stroke due to exertion, cold temperatures, and excitement. Hunters should recognize symptoms, take breaks, and have a plan in case of emergencies. Learning Hands-Only-CPR can also save lives.
A study by Weill Cornell Medicine researchers found that SARS-CoV-2 virus infection causes significant damage to mitochondria in infected cells, leading to an overactive renin-angiotensin-activation-system (RAAS) and associated blood clotting. This damage contributes to the multi-organ damage seen in severe COVID-19.
Researchers discovered that heart cockle shells have translucent areas with hair-thin strands that deliver specific wavelengths of light into the bivalves' tissues. This natural system filters out bad wavelengths and channels in optimal wavelengths for photosynthesis, benefiting the clams' symbiotic algae.
A study published in the Journal of Raptor Research found that turkey vultures in southern California are still exposed to anticoagulant rodenticides, even with recent bans in place. The researchers recommend continued monitoring and adherence to legislation regarding rodenticide use.
Researchers found that female locust's digging valves wear down significantly despite being used only 3-4 times in a lifetime. The study demonstrates the 'good enough' principle in evolution, where extra resources are not invested in organs with specific purposes performed adequately.
A new study published in Nature Aging details the changes in muscle regeneration over time, finding that immune cells exhibit differences in abundance and reaction time between age groups. The research also identifies altered stem cell states, leading to discoordination in the process of muscle repair in older mice.
Drones offer a hands-off option for surveying raptor nests, providing an efficient and safer alternative to traditional methods. Researchers found minimal impact on raptors and higher safety for both humans and birds compared to approaching nests by foot.
Researchers found that urban Red-shouldered Hawks exhibit stronger aggressive defense behaviors when nesting close to the ground. The study highlights the importance of understanding individual personality traits and environmental factors in determining nest defense behavior.
Researchers discovered that sea anemones reshape their entire bodies to maintain the same overall form after injury, contrary to other regenerating animals. This process involves molecular changes across the body, including the activation of metalloproteases, to restore proportionate shape and function.
This special issue of Calcified Tissue International presents a collection of critical reviews and original research articles on osteogenesis imperfecta (OI), covering essential aspects of the condition, including its nosology, genetics, and clinical presentation. The contributions also discuss treatment strategies for both children an...
Dr Bøsch's work explores betalains' potential to impact blood pressure, diabetes, cardiovascular health, and gut microbiota. The award highlights the significance of her research in advancing functional food and feed applications with implications for human and animal health.
Researchers at Uppsala University analyzed fossilized feces of dinosaurs, revealing undigested food remains and plants, which helped recreate the structure of ecosystems during the Late Triassic period. The study suggests that early herbivorous dinosaurs' love for plant shoots was crucial to their evolutionary success.
Archaeologists have discovered that early North Americans made needles from the bones of fur-bearers, including foxes, hares, and cats, which were likely used to create garments for warmth. The findings provide strong evidence for tailored garment production using bone needles and fur-bearing animal pelts.
New research from the University of Georgia suggests that turkeys are adapting their behavior in response to hunter activity, making them harder to detect and harvest. Hunters may need to adopt more creative and patient strategies to succeed in the future.
Under-ice species in the Arctic are facing significant threats as sea ice melts at a faster rate than anywhere else on Earth. Researchers studying microbial organisms in four environments found that the under-ice mix of species was the least diverse, composed mainly of specialist plankton and microbes adapted to harsh conditions.
A fossilized skeleton found in Bristol has been identified as Cryptovaranoides microlanius, a tiny lizard with sharp teeth, and dated to the Triassic period. The discovery shifts the origin of the Squamata group back by 35 million years, confirming its relationship to modern anguimorphs.
A team of scientists has pinpointed a critical neural circuit for female sexual rejection, revealing how the brain integrates signals to shape behavior. The ventromedial hypothalamus, specifically progesterone-sensitive neurons in the anterior VMH, play a crucial role in determining whether a female accepts or rejects mating attempts.
A long-term study found that warmer winters driven by climate change reduce the number of offspring raised annually by the federally threatened Florida scrub-jay by 25% since 1981. This is due to snakes becoming a primary nest predator in warmer weather, leading to increased reproductive effort but lower success rates.
Researchers developed a platform to produce mature, uniform organoids using a three-dimensional engineered membrane. This breakthrough enables consistent quality and improved efficiency for practical applications in clinical trials and drug development.
Researchers discovered that bats can navigate through obstacles even with their critical auditory pathway temporarily blocked. The bats adapt by changing their flight path and vocalizations, suggesting an innate ability to launch a Plan B in times of diminished hearing.
Researchers discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body. This finding paves the way for simpler and cheaper drugs to control obesity and weight gain.
A 16-year study on Seychelles warblers found significant correlations between rainfall fluctuations and the likelihood of 'divorce' in pair bonds. This research highlights the impact of environmental factors on social dynamics and reproductive strategies in wildlife, particularly in species vulnerable to climate change.
Researchers are developing a novel vaccine and exploring the use of bile acids to fight necrotic enteritis, a preventable intestinal disease in poultry that costs the industry up to $6 billion annually. The vaccine, known as MEFA, targets multiple virulence points of the disease-causing pathogen, providing better protection against inf...
Researchers at Osaka Metropolitan University found that suppression of Pcdh8 is essential for proper notochord elongation in zebrafish embryos. This study may lead to novel tumor therapies in humans due to the gene's role in controlling cell proliferation.
Researchers explore adapting agricultural techniques, such as integrated pest management, to treat cancer. By managing cancer as a chronic condition, adaptive therapy aims to overcome treatment resistance and improve patient outcomes.
Researchers identified critical proteins involved in animal stem cell regulation, including SOX and POU transcription factors, which existed in single-celled organisms over 700 million years ago. These ancient proteins retained functional properties that enabled them to induce stem cell reprogramming in mouse cells.
Researchers created an animal model with a targeted mtDNA mutation to advance understanding of mitochondrial genetic disorders. The study found significant changes in brain structure and function, as well as metabolic abnormalities, linking mitochondrial dysfunction to cognitive-metabolic impairments.
Researchers found chimpanzees of all ages displayed contagion of grooming and playful behaviors, with younger chimps more susceptible to play contagion. This behavioral contagion may help strengthen social bonds by reinforcing friendly behaviors.
Researchers at Tokyo University of Science have developed a novel co-culture system that facilitates cultivating multiple indigenous skin bacteria in a balanced state. This breakthrough allows for detailed analysis of the biology of indigenous skin bacteria, which can lead to new treatments for skin diseases and improved quality of life.
Researchers suggest that manatees may have only become a permanent fixture in Florida after Europeans colonization began, contradicting the common assumption of their long history in the state. The study suggests that warming waters and human activities may have encouraged the manatees to stay and breed.
Researchers at the Salk Institute identified a specific brain circuit responsible for slowing anxious breathing, connecting the frontal cortex to the brainstem. This discovery may offer a scientific explanation for the beneficial effects of practices like yoga and mindfulness on alleviating negative emotions and could lead to the devel...
A team of researchers has developed Janus crystals that capture humidity from the air with high efficiency, enabling a spontaneous and energy-free process for collecting potable water. The discovery could provide an endless source of clean water, addressing global water scarcity issues.
Iain Couzin, a pioneer in collective behaviour research, has been honoured on the prestigious Global Highly Cited Researchers list by Clarivate Analytics. His work seeks to uncover core principles behind collective behaviour in nature, using cutting-edge technologies such as virtual reality and imaging hangars.
Researchers aim to shed light on how hearing impairment affects auditory perception, particularly in complex environments. They will use animal models to examine neural mechanisms contributing to difficulties in sound localization.
A study of paper wasps found that species near the equator tend to be larger than those at higher latitudes. The researchers analyzed 429 specimens from 39 species and found a direct correlation between latitude and body size.
A new Harvard study finds humans possess higher metabolic rates than primates and apes, allowing for bigger brains, longer lifespan, and increased reproduction. Humans have 'escaped a tradeoff' between resting and active metabolism due to unique sweating ability.
Researchers at Uppsala University developed a mathematical model to understand how seabird species coexist on isolated islands. The model shows that different species use distinct fishing zones, maximizing energy intake based on traits like wing length and diving depth.
Researchers from UC Riverside have identified the oldest known ecdysozoan, Uncus dzaugisi, dating back to the Precambrian period. This discovery fills a significant gap in understanding the origins of this diverse animal group, which includes nematodes, arthropods, and scalidophora.
Research highlights edoxaban's effectiveness in reducing stroke and blood clots for patients after bioprosthetic heart valve replacement. Edoxaban was found to be equally or more effective than warfarin, with a predictable pharmacokinetic profile and reduced burden on patients.
A team of researchers analyzed historical marking data from the Discovery Marking Program to investigate Antarctic blue whale population structure. They found frequent mixing among ocean basins, indicating a single circumpolar population. This study provides valuable insights into the conservation of this endangered species.
Researchers from ETH Zurich developed an AI-powered method for mouse behavior analysis, reducing the need for more animals while maintaining meaningful results. The new approach focuses on transitions between patterns of behavior, providing a single, robust statistical value.
Researchers discovered that NMDA receptors set the baseline level for neural network activity, helping maintain stable brain function. The study's findings suggest potential innovative treatments for diseases linked to disrupted neural stability.
Researchers at Niigata University successfully generated rat offspring from ovarian oocytes transplanted into mice, overcame previous challenges in producing fertilized eggs and embryos.
New research reveals that 'cool' white lights used in modern car headlights cause moths to fly erratically and be more likely to collide with cars. By switching to warmer-coloured LEDs or different LED technology, the impact on moths can be dramatically reduced.
A new combination of immunotherapy and epigenetic drug may transform resistant pancreatic tumors into susceptible ones, according to a study by Johns Hopkins Medicine researchers. The treatment showed promise in a subset of patients, with tumor shrinkage and durable responses observed over several months.
Researchers have successfully transplanted human stem cell-derived heart cells into monkeys with a rare heart condition, offering a potential treatment for congenital heart defects. The study demonstrated the safety and integration of these cells into the host myocardium, paving the way for future clinical applications.
Researchers developed a cheap Bluetooth beacon to track animals in urban areas using mobile phones. The device provides regular updates on animal movements and social networks, helping unlock secrets of urban wildlife.