Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The American Association for Anatomy (AAA) has announced the recipients of its 2025 Spring Awards, honoring excellence in various fields of study. The awards include the Henry Gray Scientific Award, A.J. Ladman Exemplary Service Award, and others.
A team of researchers from Florida Atlantic University, San Diego Natural History Museum, and SeaWorld San Diego collaborate to digitize a rare vaquita skeleton, providing a valuable resource for conservation efforts. The scans resulted in three terabytes of data and will be used to create replicas for public display and education.
Two non-retinoid compounds were identified that improve cell surface expression of rhodopsin in 36 genetic subtypes of retinitis pigmentosa and protect against retinal degeneration in mice with the disease. The treatment showed improved overall retina health and function, prolonging photoreceptor survival.
A comprehensive survey predicts that 36% of anurans' habitats worldwide will be threatened by rising temperatures and water scarcity. The Amazon and Atlantic Rainforest, home to the most diverse anuran species, will face devastating effects from drought events.
A new study reveals that delta opioid receptor agonist KNT-127 has a rapid and effective antidepressant effect with minimal side effects. The research highlights the molecular mechanisms underlying its action, including mTOR signaling pathways and Akt activation in the medial prefrontal cortex.
A team of researchers from UniTrento examined how ants manage traffic congestion using pheromone trails and observed individual ant movements. Their findings could provide a model for optimizing autonomous vehicle traffic flow, reducing congestion and emissions.
Researchers will focus on novel non-plastic materials used for oyster reef restoration, evaluating their impact on surrounding marine habitats. The project aims to find solutions that bring the natural environment back after degradation from storms or human impact.
Lekking, a mating system where males display for females without forming lasting bonds, is found to be remarkably stable and rarely evolves into other systems. In contrast, resource-defense polygamy is identified as fragile and frequently reverts to monogamy, often associated with higher extinction rates.
A new self-destructing vaccine provides improved safety and protection against TB in macaque monkeys, outperforming the standard BCG vaccine. The 'kill switch' mechanism eliminates the risk of accidental infection, offering a safer vaccination option for immunocompromised individuals.
Researchers at the University of Parma and Sant'Anna School in Pisa developed a new approach to understand how the brain controls spontaneous movements in natural situations. The study used telemetric devices to record hundreds of neurons from the brains of monkeys, revealing complex synergies between individual neurons that allow for ...
Cricket frogs use a combination of underwater push and leg movement to propel themselves out of the water, resulting in a 'belly flop' motion. This discovery could lead to advancements in bio-inspired robotics and water testing systems.
Researchers have identified a 177-gene signature common to metastasis across cancers, allowing for personalized risk assessment and potential therapies. The discovery could lead to broader treatment options, faster drug access, and improved patient outcomes.
Researchers at the University of Gothenburg have discovered an antibody-like molecule, E10, that can protect mice from various influenza viruses. The molecule targets a conserved part of the virus's surface protein shared across multiple influenza types, providing effective protection against seasonal epidemics.
Researchers argue that zoos should adopt a rational approach to population management, balancing education and conservation goals with the reality of animal mortality. Planned culling can help maintain self-sustaining populations and reduce carbon footprint by utilizing in-house meat supplies.
Researchers found that carrots can enhance the body's ability to regulate blood sugar and positively influence the composition of gut bacteria. The study used mice with type 2 diabetes and found improved glucose tolerance after consuming carrot powder.
Scientists at Yale University have discovered that electrical synapses play a crucial role in filtering sensory information, enabling animals to make context-appropriate choices. The study, published in Cell, demonstrates how a specific configuration of electrical synapses enables animals to prioritize relevant details and focus on the...
Macronucleophagy helps maintain cell viability in nitrogen-starved yeast by modulating micronucleophagy. Uncontrolled micronucleophagy causes cell death, but a critical role for macronucleophagy was found to prevent this.
Researchers have reconstructed the evolutionary origin of the complex configuration of multiple sex chromosomes in echidnas using their nearly gapless genome sequence. The high-quality data helped trace genetic events that led to this remarkable chromosomal arrangement, including chromosome fusion and fission events.
The University of Texas at Arlington's Amphibian and Reptile Diversity Research Center (ARDRC) has expanded its library with a donation of over 10,000 rare items, including books, scientific journals, and reports. This addition will provide scientists worldwide with access to a wealth of literature on reptiles and amphibians.
A team of scientists at USDA and Iowa State University used generative AI to identify compounds that can reduce enteric methane emissions in cows. Bromoform, a naturally occurring compound found in seaweed, showed promise in reducing methane production by 80-98% when fed to cattle.
Researchers developed a novel inhalable therapeutic delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by marine mussels. The approach leverages the adhesive properties of mussel proteins to enable selective payload release and minimize adverse effects.
A study by Osaka Metropolitan University experts found that male medaka can mate up to 19 times a day, releasing more than 50% of their daily sperm output in the first three matings. The fertilization rate decreases significantly after this point, with some cases showing no fertilization.
Researchers found significant functional variations between rodent and human PD-1 due to evolutionary divergence. The study reveals a unique motif present in most mammals but missing in rodents, leading to uniquely weaker rodent PD-1.
A new NIH-funded study uses advanced genetic analysis tools to map how aging affects different brain cell types. The results show that some cells, like hormone-controlling cells, undergo more age-related changes in genetic activity than others.
Neuroscientist Professor Raz Yirmiya reveals a vital link between inflammation and depression through groundbreaking research. His work suggests that both activation and suppression of the immune system can trigger depressive symptoms, highlighting the need for personalized treatment approaches.
Researchers at POSTECH developed an innovative injectable adhesive hydrogel that regenerates bone using harmless visible light. The hydrogel addresses limitations of existing treatments by simultaneously achieving cross-linking and mineralization without separate bone grafts or adhesives.
The BfR2GO issue highlights Campylobacter as a common pathogen behind foodborne infections in Germany, emphasizing proper food handling. The magazine provides an overview of kitchen hygiene and includes a pull-out poster with essential tips.
A collaborative study reveals distinct mechanisms of plant and animal response to climate change in their life-cycle phenology. The research team compiled a global phenological dataset, showing that plants' late-season phenophases advance more significantly than animals', potentially due to increased plant productivity.
Researchers at OIST have developed a customizable method for studying detailed dental characteristics of living fish and vertebrates without harming them. This approach allows for non-destructive examination of tooth replacement and development over time, revealing valuable information on feeding habits and comparative anatomy.
Scientists develop novel MST detection method using CrAss-like phages (CLPs) to detect human fecal contamination, showing high efficacy and accuracy. The method uses PCR to detect CLP DNA, offering a cost-effective and selective approach to monitoring water quality.
A new study found that a unique population of large fish-eating herring has evolved in the Baltic Sea, exhibiting faster growth rates and lower levels of pollutants. These herring have adapted to the brackish water by switching from plankton-eating to a fish diet, with potential benefits for human consumption.
Researchers used bioacoustics to identify individual leopards through their vocalisations, which proved 93.1% accurate in identifying each leopard's distinct 'sawing roar'. This technique has the potential to aid in population estimates and mitigate human-wildlife conflicts.
Researchers developed biodegradable polymeric nanoparticles that selectively target cancer cells with two approved drug pairs for skin and breast cancers. The treatment showed significantly enhanced therapeutic effects, reduced tumor size, and prolonged median survival in mice.
A comprehensive analysis of medical AI technologies highlights their potential in improving diagnostic accuracy and customizing treatments. However, challenges such as data collection and analysis, biases, and patient privacy concerns need to be addressed through standardized evaluation protocols and effective collaborations.
Scientists investigated the role of ancient VR type-1 (ancV1R) receptor in pheromone detection using knockout mice. The study found that ancV1R-deficient female mice had impaired pheromone detection and exhibited abnormal sexual behavior.
Researchers discovered a novel vulnerability in prostate cancer cells that starves them of critical nutrients called amino acids. By inhibiting two proteins, GCN2 and p53, the team found a way to effectively destroy prostate tumors.
Researchers at Cornell University have created mini virtual reality (VR) headsets called MouseGoggles, which allow mice to navigate virtual environments with greater immersion and accuracy. The technology has the potential to reveal insights into spatial navigation and memory function, shedding light on disorders like Alzheimer's disease.
Scientists at the University of Plymouth are creating a humanised meningioma model to study interactions between immune cells and tumour cells, enabling the development of effective therapies for NF2-related schwannomatosis. The model will be made available worldwide to test new treatments and reduce clinical trial delays.
A study by Durham University found that bonobos orphaned by the illegal trade in bushmeat and pets can develop social abilities despite early life trauma. Researchers observed 83 bonobos at different stages of their lives, finding that female bonobos' social skills increased with age, while males' decreased, similar to wild interactions.
A six-year study examining 38 clinical isolates of Cryptococcus found genes and gene alleles associated with disease severity. The research aims to develop new treatments targeting these genetic variations, predicting disease outcomes and improving patient care.
A new study highlights how small grants to local projects worldwide can yield success in advancing global ocean conservation and equity. The research examines the effectiveness of the Marine Conservation Action Fund (MCAF) in promoting social equity and supporting local leaders in addressing ocean health challenges.
A genomic analysis reveals eight different sex chromosomes in 11 species of the frog, indicating unique and newly evolved genes for male or female sexual differentiation. This unexpected variation allows researchers to explore rapid evolution in sex determination, with possible 'on-off switch' genes orchestrating sexual differentiation.
A new study suggests that the northern muriqui monkey population remains at risk despite being almost four times larger than it was in 1982. Habitat disturbances are thought to be a contributing factor to the population decline, with predation and environmental stressors such as climate change also playing a role.
Researchers developed a near-infrared light-responsive implant surface that accelerates bone-to-implant integration by reducing acute inflammation and promoting mesenchymal stem cell recruitment. Bone-to-implant integration was accelerated from 28 days to just 14 days, doubling the speed in animal experiments.
A new study detects pre-malignant pancreatic lesions using Diffusion Tensor Imaging (DTI), a form of MRI, which could enable early diagnosis and effective therapies. The detection was successful in both transgenic mice and human samples, opening the way to non-invasive diagnostic tools for PanINs.
Humpback whales' reproductive success is linked to maternal characteristics and energy balance. Researchers found fetal growth rates increased with maternal length and energy demands peaked in the final third of pregnancy, coinciding with fasting and migration. This study highlights a vulnerable period for pregnant humpback whales and ...
The ARC will promote research groups and consolidate others to control greening, especially in areas not currently covered. The center aims to mitigate the disease's impact on citrus production, which has declined by 36.5% and fruit production costs are approximately 20% higher.
Researchers found that giraffes prefer flat terrain and avoid steep slopes of more than 20° due to energy requirements and risk of falling. This limits their access to habitats in protected reserves, with nearly half of Namibia's habitat being unusable for giraffes.
Researchers at Nagoya University have discovered a unique motor control system in frogfish's first dorsal fin, enabling their 'fishing' behavior. The study reveals how motor neurons changed location as their function shifted from swimming to hunting.
A new UC Berkeley study analyzed over 60,000 animal observations and found no conclusive evidence of inequity aversion in non-human species. However, the researchers suggest that some animals may exhibit disappointment or social protest when their expectations are not met.
Researchers discovered that serine inhibits the cell wall remodeling necessary for Clostridium perfringens to form spores, preventing food poisoning. The study provides insights into the underlying mechanism of spore formation and may lead to new strategies for preventing foodborne illnesses.
Researchers found that rutting calls of Siberian wapiti stags reflect their harem-holding status and individual characteristics. The study suggests that these acoustic displays enable females to assess a male's quality from a distance, while also signaling to rivals whether it's worth challenging him.
Researchers analyzed human remains from a settlement site in Kosenivka, Ukraine, providing insights into the lives of ancient people. The study found that meat made up less than 10% of their diets, with plant-based foods being the primary source of nutrition.
Increasing serotonin levels in the gut epithelium improves symptoms of anxiety and depression in animal studies, suggesting a new therapeutic approach. The study also highlights the risk of digestive issues in children exposed to antidepressants during pregnancy.
A study by Tulane University researchers found that tumors in female fruit flies grew 2.5 times larger than those in male fruit flies due to sex-based differences in immune response. The stronger innate immune response in females accelerated tumor growth.
A new study has linked the diversity of a wild bird's gut microbiome with its ornamentation and body condition. Researchers found that a cardinal's gut microbiome can be predicted by its body condition, and the quality of its ornamentation, such as red plumage and beak. This discovery has important applications for conservation biology.
A new animal study published in the Journal of the Endocrine Society found that early life exposure to polychlorinated biphenyls (PCBs) may lead to behavioral problems in rats. PCBs, which have been banned for decades, can reprogram a developing neuroendocrine system and cause developmental and hormonal changes.
A study from Tulane University found that a low-protein diet in one generation can lead to lower birthweights and smaller kidneys in offspring across multiple generations. The findings suggest that food scarcity or malnutrition may result in decades of adverse health outcomes.
A new study highlights the devastating impact of illegal ritualistic hunts in West Bengal, India, where over 5,000 animals are estimated to be killed annually. The research reveals that these large-scale events target more than 90 species, including those at risk of extinction.
Renowned researcher Iain Couzin has received the 2024 Fyssen International Prize for his groundbreaking work on collective behaviour across species. His research, which explores how coordinated patterns emerge from individual behaviours in diverse animal systems, significantly advances our understanding of group dynamics.