Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study published in PLOS Biology suggests that male birds contribute less to helping their families because they prioritize scouting for new habitats and breeding opportunities. This trade-off with dispersal may explain why one sex invests more in family help than the other across various animal societies.
A study by a University of Mississippi professor found that the vocalizations of baby chickens, known as 'peeps' and 'whistles', can indicate stress levels in avian animals. This breakthrough could improve animal welfare in the poultry industry and lead to more humane practices.
A study across 292 species found that neoplasia (uncontrolled growth) rates decrease with longer gestation times, while malignancy rates increase with higher adult masses. This contradicts Peto's paradox and suggests complex interactions between life history traits.
Fossils from over 600,000 years ago show a shift in animal communities between warm and cold climate fluctuations. The Notarchirico site provides evidence of the emergence and disappearance of species such as cave lions, straight-tusked elephants, and red deer.
A new parasite, Pachysentis canicola, has been discovered on the Channel Island fox, causing severe intestinal damage and inflammation in infected individuals. The study highlights the importance of biosecurity in the Channel Islands National Park and underscores the impact of human activity on isolated ecosystems.
A new tracking method using mobile phone networks and Bluetooth technology provides reliable high-frequency tracking data for urban living animals. Field testing with birds demonstrated the feasibility of this approach to study movements and social networks.
The study found that uneven distribution of resources gives some individuals more access to play than others. Wildlife is a major draw for nature-based tourism, but human recreation has unintended consequences for biodiversity. To coexist with wildlife, it's essential to follow common-sense rules and minimize disturbance.
Researchers at USC Dornsife discover that mifepristone increases mitophagy to the same extent as rapamycin, potentially extending lifespan. The study found that combining the two drugs does not offer additional benefits and slightly reduces lifespan, suggesting they act through the same biological pathway.
Researchers at SFSU have created three-dimensional molecular and anatomical maps of the inner neuronal circuitry of octopus arms. These 3D reconstructions revealed that cells at the tip of an arm are different from those at the base, allowing for new questions to be posed about how cells communicate with one another.
Researchers used a mouse model to assess the impact of senolytic agents dasatinib and quercetin on pelvic organ prolapse. The study found that D+Q injections did not result in significant differences in prolapse development but reduced cellular senescence markers.
The international project will analyze temperature-sensitive proteins in animals adapted to different thermal environments to understand how they perceive temperature changes. The study aims to uncover the molecular mechanisms underlying cold perception in animals, enabling them to initiate physiological responses crucial for survival.
A new study by researchers from The Hebrew University of Jerusalem challenges conventional beliefs about decomposition processes in arid environments. Larger insects such as termites and beetles play a crucial role in decomposition, with peak rates during the summer in arid sites.
A KAUST-led global study found that livestock management and climate explain woody species coverage in arid environments. Managing grazing pressure and type of herbivore can allow for more sustainable production in these ecosystems.
Histomonosis, a deadly parasite that decimates turkey flocks, is being studied for its transmission routes and potential treatments. Researchers aim to understand how the parasite survives and spreads, with a focus on fecal-oral transmission via contaminated feces or cecal droppings.
A research team, led by Francesco Ferretti, located signs of white sharks at four sites in the Sicilian Channel, a stronghold of the endangered species. The team used improved methods and technologies, including eDNA sampling and camera traps, to detect the presence of the sharks.
Researchers from UT Arlington sequenced RNA genes of pythons, discovering conserved pathways in humans that are activated uniquely by these snakes. This knowledge helps explain intestinal regeneration and metabolism changes, offering potential therapeutic targets.
Dr. Wai Hong Lo, PhD, has been appointed as the new Editor-in-Chief of ASSAY and Drug Development Technologies, succeeding Dr. Bruce Melancon. Dr. Lo aims to enhance online accessibility, incorporate visuals, and increase social media engagement to reach a broader audience.
Researchers found Edaravone inhibits growth of brain tumor stem cells and prolongs survival in mice with glioblastoma. The study suggests repurposing Edaravone as a potential treatment for this aggressive brain cancer.
Providencia rustigianii carries a type III secretion system and cytolethal distending toxin virulence gene, increasing its pathogenicity, similar to Salmonella.
Glioblastoma, the most malignant primary brain tumour, has an 18-month median survival rate despite treatment. New research from the University of Ottawa suggests a drug used to slow ALS progression may also suppress glioblastoma's self-renewing cancerous stem cells.
A new study found that artificial nests outperform natural nests in boosting African penguin breeding success by 16.5%, but each type of nest has strengths and weaknesses. Colony-specific conservation strategies are needed to address the unique threats faced by each colony.
Researchers developed a new algorithm to decode neural signals representing hand postures, enabling more precise control of neuroprostheses. The study, conducted on rhesus monkeys, shows that posture-related activity in the primate grasping circuit is crucial for accurate control.
A recent study employs zebrafish to model Nager syndrome, revealing the role of sf3b4 mutations in facial development and apoptosis. The research suggests that FGF8 plays a critical role in disease pathogenesis and provides a potential therapeutic strategy.
A study has revealed that the cpb2 gene enhances the persistence of C. perfringens in swine, with potential implications for disease management. The researchers found that cpb2 is associated with host species-specific adaptations, particularly favoring the porcine intestinal environment.
A study published in Biology Letters reveals that harbor seals in Alaska's Iliamna Lake are genetically isolated from other seal populations across the Pacific. The researchers found significant differences between the lake seals and marine populations, suggesting they may be a unique endemic form of harbor seal.
Researchers detected microplastic particles in the breath of wild bottlenose dolphins, suggesting inhalation may be a key route of exposure. The study supports the idea that dolphins could be exposed to potentially harmful microplastics through this pathway.
Wildlife rangers from the Uganda Wildlife Authority successfully monitored lion populations in the Murchison Falls Nile Delta, estimating a density of 13.91 lions per 100 km². The study highlights the cost-effectiveness and value of rangers' skills in conservation efforts.
An international team of researchers has discovered seven new species of tree frogs in Madagascar, characterized by their high-pitched whistling calls. The unique vocalizations are believed to serve as self-promotional advertisement calls to convey information about the male frog's suitability as a mate.
Researchers found that male mice deescalate aggressive encounters by running over to a female mouse to distract the aggressive male mouse. This 'bait-and-switch' tactic reduces further conflict and helps maintain social hierarchy in groups of mice.
A recent study led by University of Wyoming scientists found that managing free-roaming horses within the Bureau of Land Management's maximum appropriate management levels would benefit sage grouse populations. Grazing by wild horses can reduce shrub density, vegetation cover, and abundance of key forbs used by sage grouse.
In a study published in Journal of Evolutionary Biology, researchers found that mountain chickadees sing differently than their close relatives, the black-capped chickadee. The birds' unique songs help them distinguish between friends and foes, reducing interbreeding and competition.
Researchers at University College Cork found that wild birds' gut microbiome impacts their growth, weight, and survival. The study manipulated the birds' microbiome by feeding them beneficial bacteria Lactobacillus kimchicus.
A novel nanoparticle therapy targets fat absorption in the small intestine, showing significant potential to prevent diet-induced obesity. The treatment involves inhibiting an enzyme called Sterol O-acyltransferase 2 (SOAT2), which plays a critical role in fat absorption.
In a 30-year experiment, scientists witnessed rapid evolution of marine snails in response to pollution and climate change. The snails' adaptation was driven by genetic diversity and gene flow from neighboring populations, allowing them to rapidly adapt to their new environment.
Researchers investigate how liver necroptosis triggers inflammation in both organs, leading to cognitive impairment. Studying aging mouse models, they found that liver necroptosis causes systemic inflammation affecting brain function.
Carl-Philipp Heisenberg, a developmental biologist, has received a five-year €1M NOMIS grant to investigate the role of cytokinesis in early embryo development. His research aims to challenge the current understanding and uncover the mechanisms that shape complex life forms.
Researchers used fluorescein angiography to visualize neural blood flow in rats and rabbits with chronic nerve compression neuropathy, correlating findings with electrodiagnostic testing. The study showed promising results for the method's potential to improve diagnosis and treatment outcomes in carpal tunnel surgery.
Researchers have developed a cell culture platform to form two distinct, interconnected vascular networks, replicating human physiology and reducing animal testing costs. This breakthrough enables the study of cellular interactions in vascularized tissues.
A new study uses insect evidence from illegally killed rhinos to determine the post-mortem interval. This technique has been used to construct cases against poachers and has led to a rebound in rhino populations over the past 30 years.
A new University of Colorado Boulder study sheds light on why paternal mitochondrial DNA is eliminated during development. The research found that delaying this process can lead to lasting neurological and behavioral problems in adults. Treatments such as Vitamin K2 may offer new hope for preventing or treating these disorders.
A study published in Scientific Reports found that rats' social structures are more complex than previously thought, with varying patterns of dominance and coexistence. The researchers' findings suggest that psychiatric medications may need to be re-evaluated due to the complexity of rat social dynamics.
A recent study by The Jackson Laboratory reveals that reducing calorie intake can significantly extend the lifespan of mice, with the most robust animals living the longest. However, the researchers found that losing weight on these diets had a negative impact on lifespan in humans.
A new study published in Journal of Biogeography finds that malaria-like blood parasites increase in prevalence with the number of bird species present, highlighting the importance of host diversity. The research also shows that parasites can spread more rapidly when they specialize in closely related or functionally similar bird species.
A recent study by Imperial College London has found that dogs swimming in contaminated ponds are releasing harmful levels of two pesticide medications. The chemicals, imidacloprid and fipronil, were used as flea and tick treatments for cats and dogs, posing a significant threat to aquatic life.
New research from Binghamton University reveals that Mexican jumping bean larvae respond differently to various lighting conditions, with red light stimulating the most vigorous jumps. However, damage to their 'bean' hosts hinders their ability to jump away from stressors.
Researchers at Rice University have developed adhesive bacteria and proteins that can help efficiently decompose PET, a notoriously resistant type of plastic. The engineered microbes demonstrate a 400-fold increase in adhesion to PET surfaces, making them a potential solution for tackling plastic pollution.
Researchers identified AM-101 as a potential new way to enhance radiation therapy for patients with lung cancer that has spread to the brain. The drug's ability to activate GABA(A) receptors increases autophagy in lung cancer cells, making them more sensitive to radiation treatment.
Researchers found that geckos utilize the saccule, a part of their inner ear traditionally linked to balance, to detect low-frequency vibrations. This 'sixth sense' plays a complementary role in the geckos' normal hearing and sensory perception.
Researchers at Michigan Medicine have discovered a new subtype of aggressive prostate cancer and identified a potential degrader to target it. The study found that a genetic alteration in the CDK12 gene drives cancer development, and a degrader targeting this gene shows promise in destroying cancer cells.
A study from Goethe University Frankfurt reveals that venomous crustaceans, specifically remipede crabs in Mexican cenote caves, contain a variety of toxins with pharmacological potential. The xibalbines peptides effectively inhibit potassium channels and activate signaling pathways involved in pain sensitization.
A new publication provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. Regular narrative reviews are prone to biases, but systematic reviews follow a rigorous and transparent methodology, helping researchers make sense of conflicting reports and identify gaps in the field.
A new study explores a promising combined therapy for multiple sclerosis, using tolerogenic dendritic cells modified with myelin antigens. Researchers found that these cells from patients have a persistent pro-inflammatory signature, making them less effective compared to those derived from healthy individuals.
A new study reveals that ant agriculture and fungus farming originated 66 million years ago, with colonies of ants beginning to cultivate fungi in the aftermath of the asteroid impact. This partnership has evolved over time, with some fungal crops becoming completely reliant on ants 27 million years ago.
Researchers have developed a promising new drug, RI-AG03, that successfully targets and blocks both major aggregation-promoting 'hotspots' of the Tau protein. The peptide-based approach shows significant potential in preventing the build-up of Tau proteins and neurodegeneration, addressing a critical gap in current treatments.
Researchers have created the largest and most complete map of the fruit fly brain, detailing over 50 million connections between neurons. The study provides critical information about brain wiring and underlying signals, paving the way for future studies on larger-brained animals.
Researchers discovered a cache of rare monkey fossils in the Dominican Republic, providing new insights into the anatomy and ecology of the extinct Antillothrix bernensis. The study suggests that male and female monkeys were monomorphic and weighed up to five pounds, with a diet mainly consisting of fruit.
A team of scientists has successfully mapped the entire brain of Drosophila melanogaster, a fruit fly, using electron microscopy dataset and connectome analysis. The complete map will help researchers understand how different circuits work together to control behaviors like motor control, courtship, and decision-making.
Researchers create a complex model of nematode worm behavior, accurately mimicking its movements and offering insights into animal behavior. The findings have significant implications for medical research, particularly in the study of movement disorders like Parkinson's disease, and could also improve robotics.
Researchers at La Jolla Institute for Immunology have developed six lines of humanized mice to study human cases of COVID-19, shedding light on SARS-CoV-2's movement through the body and varying symptoms. The models help understand how different genetic backgrounds influence disease progression.
A study by University of Potsdam researchers analyzed the data of 1585 wild animals fitted with GPS collars, finding that 30 species changed their behavior significantly after release. The animals generally recovered within four to seven days, with larger ones and those in human-influenced habitats returning more quickly.