Articles tagged with Pharmaceutical Industry
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Researchers at the University of Illinois Urbana-Champaign have developed a new method for synthesizing thermally stable Ni(I) compounds that opens new avenues for building complex molecules. The new catalysts exhibit rapid ligand substitution, exceptional performance in key reactions, and chemo-selectivity.
Research from Bentley University's Center for Integration of Science and Industry shows public companies with price negotiable drugs under IRA were more profitable than comparable companies in the S&P500. The study also found that revenues from these drugs exceeded normal returns on investment before price negotiations began.
A national clinical trial found that abemaciclib, an oral cancer drug, may slow tumor growth in patients with aggressive meningiomas with specific genetic mutations. The trial showed promising results, with a median progression-free survival of 10 months and a median overall survival of 29 months.
A 2025 survey found that U.S. adults view opioid overdose as a serious problem, with differing opinions on who is responsible for reducing overdose rates. The study suggests varying preferences for future actions to address overdose among conservatives, moderates, and liberals.
A new clinical trial, PAGODA, seeks to minimize treatment interruptions and help patients complete their chemotherapy as planned. The trial will test a structured plan to guide doctors in making small, proactive changes to chemotherapy doses to prevent treatment delays.
BGI Genomics convened its 2025 European Partnership & Networking Summit in Budapest, fostering innovation, collaboration, and growth. The event introduced its comprehensive NGS solution, Gensiro, integrating AI and automation to streamline laboratory workflows.
The article highlights the mismatch between psychedelics and economic drug development principles. Pharmaceutical companies are developing short-acting compounds and neuroplastogens to engineer trips out of the experience altogether. Dr. Sandy Hager's research suggests investors should remain cautious due to weak intellectual property ...
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A new national quality framework has been developed to evaluate medication management and clinical services provided by pharmacists in residential aged care. The PHARMA-Care National Quality Framework promotes a transparent, person-centred approach to medication management, aiming to reduce risks linked to polypharmacy.
Three new Cochrane reviews found GLP-1 drugs result in clinically meaningful weight loss, but evidence on longer-term outcomes and side effects is limited. The wider use of these drugs should consider social and commercial determinants to avoid deepening existing health inequities.
The US economy is expected to grow at 1.8% in 2026, with AI and energy infrastructure investments playing a key role. Despite this, job creation will not be strong enough to keep unemployment rates from rising to 4.8%, with the nation's economy facing uncertainty around trade policy.
A new analytical tool using Raman spectroscopy enables rapid monitoring of vaccine quality and quantity, with results in 30 seconds or less. The tool operates on the production line, saving time and money in vaccine production.
The Science/Science Careers' 2025 Top Employers Survey ranked the top companies in biotechnology, biopharmaceuticals, and pharmaceuticals based on employee responses. The survey found that companies with strong reputations as employers prioritized innovation, leadership, and work culture.
A new RNA-based therapy targeting Marfan syndrome shows promise in treating the genetic disorder, which can lead to aortic aneurysms and be fatal. The therapy, developed by Mizzou researcher Dunpeng Cai, aims to correct mutated RNA for those with Marfan syndrome.
A new study shows that direct-to-consumer pharmacy pricing can offer lower total costs (431% lower) compared to commercial pharmacies for insured patients. Out-of-pocket neurologic drug costs are 75% higher, but most medications cost less than $635 per year.
Conventional treatment methods used by municipal wastewater treatment facilities are ineffective at removing common pharmaceuticals like Prozac, fluoxetine, and loratadine from wastewater. These drugs are discharged into lakes, rivers, and streams, posing risks to aquatic organisms.
A portable device using machine learning can detect signs of concussions in real-time, providing a more objective way to assess injuries. The Mizzou Point-of-Care Assessment System combines a force plate, depth camera and interface board to track movement, balance and reaction times.
The global market for AI in pharmaceuticals is projected to reach $13.4 billion by 2035, driven by Insilico Medicine's innovative use of generative AI. The company will share its achievements at a satellite forum during BIOHK2025, showcasing significant efficiency boosts compared to traditional methods.
A study of Medicare database payments found that nearly 80% of US neurologists prescribing multiple sclerosis (MS) drugs received industry payments, with higher volume prescribers more likely to be beneficiaries. Recipients were also more likely to prescribe the company's drugs, especially if payments were larger and sustained.
Climate-related disasters pose significant disruptions to US drug manufacturing facilities, affecting nearly two-thirds of production sites. Researchers assessed the impact of disaster events on counties with US drug production facilities and found that nearly two-thirds were located in areas affected by at least one disaster declaration.
Researchers at North Carolina State University have developed a controlled evolution technique that dramatically increases plasmid DNA (pDNA) production in E. coli bacteria. This breakthrough could significantly reduce the cost of gene therapies and expedite research, making pDNA resources more accessible.
The new handbook provides a practical approach to harnessing zebrafish as a model organism for biomedical research, covering drug efficacy evaluation and disease mechanisms. It offers step-by-step experimental protocols and theoretical grounding for researchers of all levels.
The book explores innovative computing technologies transforming healthcare delivery, diagnostics, and monitoring. It covers topics like artificial intelligence, machine learning, IoT, wearable devices, and real-time communication systems.
The journal is seeking original research, viewpoints, and tutorials exploring the use of AI-driven documentation in clinical settings. Submissions should address practical applications, challenges, and future directions of AI-facilitated clinical documentation.
A new gene therapy delivery device called NANOSPRESSO could revolutionize how hospitals treat rare diseases by allowing them to create personalized nanomedicines in-house. This democratized approach to precision medicine could boost access to low-cost bespoke gene and RNA therapies, especially in low-resource settings.
Scientists at Xi'an Jiaotong-Liverpool University developed a new nanoparticle capable of carrying high doses of chemotherapy drugs while staying stable for extended periods. This innovation could make treatments more effective and reduce side effects.
Scientists have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia) during migraines. By disrupting the normal balance of nerve signaling and pain regulation, NEAT1 makes nerves more sensitive to light.
Researchers at Indiana University discovered a new way acetaminophen targets pain by inhibiting an enzyme that produces endocannabinoids. Reduced levels of these compounds may lead to decreased pain relief, providing a potential target for designing safer pain medications.
The University of Texas at Arlington offers pre-health students valuable hands-on experience through an innovative collaboration. Students in SCIE 4304 participate in immersive clinical simulation lab at the UTA Smart Hospital, developing rudimentary clinical skills and overcoming imposter syndrome.
A new study suggests that European member states must work together and provide better incentives to develop new medicines. The research highlights the need for faster approval times and stronger support for innovative drugs to attract leading pharmaceutical companies.
Imperial scientists launched a miniature laboratory into Earth orbit to engineer microbes that can produce food, pharmaceuticals, fuel, and bioplastics in microgravity. This partnership aims to create environmentally friendly and affordable non-animal foods, reducing the cost of space travel.
Three NSF-funded investigations are launching on NASA's SpaceX CRS-32 mission to ISS National Laboratory. Investigations aim to advance pharmaceutical manufacturing, develop new materials, and study active matter in microgravity environment.
Researchers created an anchoring-borrowing strategy to form artful single-atom catalysts, overcoming traditional oxidative addition steps in cross-coupling reactions. The new catalysts achieve high yields, excellent stability, and set a benchmark for turnover numbers.
A new class of antibiotic has been shown to be effective in treating MRSA infections, with a daily dose of epidermicin NI01 demonstrating equal efficacy to the current standard of care. The findings justify further pre-clinical development and could lead to new gel-type therapies for skin infections.
The updated Maurer, Meyer, Helfer, Weber: LC-HR-MS/MS Library contains over 5,500 mass spectra for parent drugs and poisons, along with their metabolites. This comprehensive dataset enables scientists to confidently identify unknown compounds and assess toxic substance risks.
ARDD 2025 to feature Nobel laureates and pharmaceutical executives discussing latest advancements in aging research. Maxwell Biosciences will showcase its CLAROMER technology enhancing innate immune system, promoting healthy longevity.
Insilico Medicine has secured a $110 million Series E financing to accelerate the advancement of its AI-driven drug discovery pipeline and platform developments. The funds will focus on refining AI models and algorithms, as well as advancing clinical validation of its flagship candidate for idiopathic pulmonary fibrosis treatment.
CrySyst's QbC framework addresses crystallization monitoring, modeling and control using research from Purdue University. The software provides guided experiment selection, semiautomated model development and reliable solutions to reduce time and material usage.
Hunter Medical Research Institute has formed a memorandum of understanding with Novartis (Aust & NZ) to explore future research projects focused on improving cardiovascular health. The partnership aims to accelerate innovation and enhance patient care through collaborative research initiatives.
Biomedical engineers at Duke University have developed a new technique that traps together cellular machinery to increase protein production rates. This approach uses synthetic disordered proteins to form compartments called biological condensates, which enhance the rate of protein production by bringing together biomolecular machinery...
The Young Institute Pharmaceutical Manufacturing Consortium aims to pioneer advances in pharmaceutical manufacturing with a focus on sterile injectables and innovative aseptic manufacturing technology. The collaboration will develop disruptive technologies, autonomous systems, and smart AI and digital technology.
Biofilm produced by Pseudomonas alcaligenes has unique structural properties and thermal stability, exhibiting antioxidant, emulsification and flocculation activity. The EPS can be used as a natural additive for the pharmaceutical and food industries with potential applications in developing sustainable or ecofriendly additives.
Researchers used drum mills to manufacture kilograms of ibuprofen-nicotinamide, a formulation that improves therapeutic efficacy and stability. The study demonstrates the possibilities of drum mills for large-scale synthesis of pharmaceutical co-crystals.
A new analysis reveals critical gaps in the UK's self-regulated system for disclosing payments from drug companies to healthcare professionals and organisations. The study finds billions of pounds in untraceable research payments and non-research payments lack clarity, with significant breaches by major companies. Researchers are calli...
A new study highlights the risk of patient organizations losing independence due to funding from pharmaceutical companies. Researchers propose establishing a single database to track payments made to patient groups, doctors, and hospitals to improve transparency.
Researchers from Institute of Science Tokyo successfully developed a multi-element perovskite catalyst that selectively oxidizes light alkanes to alcohols with high yield and selectivity. The breakthrough catalyst operates under mild conditions and exhibits excellent stability and reusability.
Researchers developed a platform to produce mature, uniform organoids using a three-dimensional engineered membrane. This breakthrough enables consistent quality and improved efficiency for practical applications in clinical trials and drug development.
A study found that 64% of clinical trials for the top 30 highest-revenue medicines had their data accessible to researchers, a significant improvement over prior assessments. Companies using independent platforms achieved higher eligibility rates than those relying on internal processes.
A recent Stanford University study has identified 33 current faculty members from Binghamton University as among the top 2% of all researchers worldwide in their fields. The researchers were ranked based on their career-long or single-year output and citation metrics, indicating their significant impact on their respective fields.
The university introduces Bachelor of Engineering in Robotics and Double Major Bachelor of Engineering Science in Process Engineering and Synthetic Chemistry to address global demand for roboticists. The programs incorporate AI-related elements and are designed to provide students with a unique skill set.
Researchers propose utilizing human 3D skin models to assess drug binding properties across different skin types. Genetic variations among minority groups can lead to starkly different drug responses across races and ethnicities.
Researchers from Tokyo University of Science have developed a new type of micelle that can effectively dissolve dyes, paving the way for more efficient and cost-effective formulations. The micelles were created using block copolymers and showed improved dye solubilization capacity compared to random copolymers.
Recent research highlights microwave-induced synthesis as a transformative potential in drug discovery and development. This efficient technique enables rapid preparation of diverse N-heterocycles, including biologically active molecules such as pyrimidines, thiazoles, and quinolines.
A recent study reveals that pharmaceutical industry sponsors dominate US cancer research, with a substantial increase in industry-sponsored clinical trials over the past decade. Federally funded studies have been underinvested and have missed opportunities for scientific advancements.
The European capacity for antibiotic research and development requires sustained investment to combat growing resistance. Collaboration and risk-sharing can help keep companies in anti-infective drug development, as a temporary funding strategy may lead to lost efforts.
Researchers at KIT develop new NMR spectroscopy method to directly measure chiral molecular structure. This enables accelerated drug screening and simplifies the search for active ingredients in pharmaceuticals. The breakthrough could lead to significant improvements in drug development.
A team of chemists has developed a novel tool to streamline the drug-making process, enabling researchers to create new molecules quickly and efficiently. The discovery of stable nickel complexes can help reduce the time to market for life-saving medicines while increasing drug efficacy and reducing side effects.
Researchers at the California Institute of Technology have successfully developed a method to recycle samarium diiodide, a crucial reagent in synthesizing molecules that can lead to new pharmaceuticals. This breakthrough enables large-scale industrial production, making it possible to create essential compounds like taxol, an anticance...
Researchers developed a one-pot process to transform aromatic ketones into esters, simplifying the reaction process, reducing reaction times, and minimizing purification steps. The method enables seven different chemical transformations and has shown notable stability and reusability, making it scalable for industrial applications.
Five pioneering firms in agriculture, manufacturing, and pharma retail have demonstrated businesses can catalyze social and environmental change. They address complex issues using scientific methods, partner with NGOs, and prioritize purpose alignment.