Articles tagged with Pharmaceutical Industry
A significant increase in illicit ketamine seizures in the US has raised concerns about the risks of non-medical and recreational use, as well as the presence of fentanyl. The study found a 349% rise in seizures from 2017 to 2022, with the highest numbers reported in Tennessee, Florida, and California.
A novel method combines biosensors and microfluidics to quickly identify mutant bacterial strains that produce industrially useful proteins. The approach enables the extraction of high-performing strains in a fraction of the time required by traditional methods.
A Pharmacy PhD student from the University of Huddersfield has won a prestigious award to present her research on how community pharmacies can contribute to preventing suicide in low and middle-income countries, particularly in Nigeria. She aims to raise awareness of suicide and train pharmacists to recognize signs and risk factors.
A new study from Cornell University found that the pharmaceutical industry can significantly reduce its environmental impact. The study analyzed the full life cycle of the HIV antiretroviral drug Tenofovir Disoproxil Fumarate (TDF) and found that energy usage is the biggest contributor to carbon emissions, accounting for up to 45% of t...
Dr. Vesna Najdanovic from Aston University won a $25,000 grant to develop greener analytical methods using ethyl lactate as a solvent for liquid chromatography. This environmentally friendly alternative reduces carbon footprint and pollution in the pharmaceutical industry.
Researchers at Nagoya University have successfully developed an ultrafast and simple synthetic method for producing indole derivatives. The new microflow synthesis method enables precise control of short reaction times, limiting unwanted dimerization/multimerization and increasing the yield of desired products.
A Bentley University study shows that the National Institutes of Health (NIH) invests similarly to the pharmaceutical industry in bringing new drugs to market. The NIH spent $187 billion on research related to FDA-approved drugs between 2010-2019, with an average investment per approved drug of $1.7 billion.
A pharmacy PhD student from Iraq has won the Best Oral Presentation award at a major international conference for pharmaceutical sciences. Haja Muhamad's prize-winning talk explored the effects of prandial dosing on dosage forms using imaging and spectroscopic analysis.
A new study found that acquisitions in the biopharmaceutical industry can disrupt trust and knowledge exchange routines between companies, leading to a higher risk of alliance termination. The odds of termination for exposed alliances are 11% greater than for unexposed ones.
Researchers from Kyushu University found that the single mechanosensitive protein VGLL3 induces fibrosis, thickening and scarring tissue. The study suggests targeting this protein could lead to new treatments against fibrosis.
A study found that having opioids at home increases the risk of overdose for those living with them, emphasizing the importance of proper disposal and education. Household prescription opioids are associated with a higher likelihood of overdose for others in the household, even if they don't have their own prescription.
A KAIST research team has developed an advanced AI-based drug interaction prediction technology that analyzed the interaction between Paxlovid ingredients and other prescription drugs. The study identified potential drug-drug interactions and alternative drugs with low adverse effects, which can aid in developing new treatments.
Researchers developed an acid-based electrochemical process to convert CO2 captured from emission sources or air into multicarbon products such as ethylene and ethanol. The new method improves energy efficiency by twofold compared to previous benchmarks.
The five finalists of the Bright SCIdea Challenge will compete for a £5,000 prize by pitching their scientific business ideas that could benefit society. The project ideas include burn treatments and environmental calculators.
Research by the University of the Basque Country found that gluten-free products often lack essential nutrients like fibre and protein. Gluten-free pasta, for example, is now made from millet instead of rice flour, improving nutrition.
The IMPACTIVE project aims to develop a sustainable alternative to traditional pharmaceutical production methods. By leveraging mechanochemistry, the team hopes to reduce waste and emissions in the industry. The initiative has already shown promising results, with potential cost savings of up to 12%.
The 6th Annual Meeting of the Labroots Drug Discovery & Development Virtual Event Series will bring together specialists to discuss ongoing research in drug discovery and development. Keynote speaker Professor Kevin Pfleger will present novel pharmacology findings, while attendees can earn free CE credits.
A University of Houston engineer has made a groundbreaking discovery that could improve pharmaceuticals by controlling the growth of ammonium urate crystals. By manipulating tautomers, researchers found that a small fraction can control crystal growth, potentially preventing crystallization and related health issues.
A £5.4 million project, backed by Innovate UK, aims to develop a new value chain to convert industrial waste gases into sustainable materials for consumer products. The consortium, including Unilever and BASF, will seek to demonstrate how the UK can cut 15-20 million tonnes of carbon dioxide emissions per year.
Researchers at Northwestern University developed a sustainable biorefinery that turns organic waste, including lignin, into valuable products. The process involves a microbial electrolysis cell that breaks down lignin into aromatic compounds with medicinal properties.
Researchers developed a new photo-oxidation method to efficiently synthesize pharmaceutical intermediates and polyurethane from perchloroethylene, a common dry cleaning solvent. The method yields high-quality compounds with minimal environmental impact, offering a promising alternative for sustainable chemical recycling.
The researchers aim to create a set of tools to help other chemists select and produce the right crystal structures for new drugs, potentially saving time and cost. By understanding how molecules crystallize, they hope to speed up the development process and lower costs.
Researchers uncover how changing trends in interorganizational deals in the pharmaceutical industry are improving drug discovery and R&D productivity. The study found that M&A-related deals drive revenue growth for large pharmaceutical companies, and academia-owned spinouts of advanced technology are increasing.
Using genetically modified Aspergillus fungi, researchers have successfully converted polyethylene plastics into pharmacologically active compounds. The process breaks down the plastics quickly and efficiently, producing commercially viable yields of asperbenzaldehyde, citreoviridin, and mutilin.
A study shows that pharmacies can offer a safe starting point for patients with opioid use disorder, leading to higher rates of retention in treatment. The pharmacy-based model increases access to buprenorphine, a lifesaving medication, for diverse patient populations and promotes racial and economic equity.
Researchers at Rice University have developed a photochemical process that simplifies the manufacture of essential precursors for drugs and agricultural chemicals. By illuminating reagents with visible light, they can form diazides in conditions far gentler than current industrial processes.
A new paper highlights the need for globally harmonized probiotic regulatory approaches, emphasizing the importance of comprehensive genomic characterization. It proposes a risk-tier system based on strain history and genome analysis, recommending more extensive testing for innovative strains before marketing.
Patent thickets and evergreening strategies hinder generic competition, leading to higher brand name drug prices. Generic entry can drop prices by 90%, affecting patient welfare. Patent expert Sean Tu advocates for a balanced patent system that promotes innovation while preventing monopolies.
A Nagoya University study found that increased use of pharmaceuticals and medical supplies during the COVID-19 pandemic contributed to a 27% increase in hospital carbon emissions. Despite reduced electricity and gas consumption, the overall carbon footprint rose due to longer hospital stays and increased intensive care needs.
A new flow photo-on-demand synthesis system using chloroform as a precursor has been successfully developed by researchers at Kobe University. The system achieves high conversion rates and can synthesize various chemical products continuously in large quantities, offering a safe, inexpensive, and environmentally friendly alternative to...
A comparison of two cancer drugs reveals that life cycle management strategy is crucial for a drug's commercial success. The research found that product sales are closely linked to the number of approved indications and inter-organizational alliances.
Researchers developed a computational protocol called MACH that can quickly determine whether a given compound will form a crystal hydrate. The tool uses rules to systematically determine where water would likely be inserted into a crystal, providing essential knowledge for drug development and formulation.
Pharmaceutical contamination poses significant risks to ecosystems due to the widespread use of medicines in humans and animals. Researchers emphasize the need for greener drug design, improved wastewater management, and responsible use of drugs.
A search of the Cambridge Structural Database found nearly 1,800 conglomerate crystal structures with spontaneous enriched chirality, augmenting synthetic building blocks for medicinal chemists. This discovery introduces a new pool of chiral molecules outside of natural sources, potentially leading to more effective treatments.
Researchers at KAUST have identified thermophilic bacteria with potential to degrade oil contamination. The study reveals that certain bacteria can secrete surfactants and absorb emulsified petroleum into their cells for degradation via enzymatic activity.
The COVID-19 pandemic led to a decline in marketing payments, while research payments remained stable despite clinical trial suspensions. Pharmaceutical and medical device companies adapted by incorporating virtual study visits and remote outcome measurement.
Researchers at NJIT have developed a new lab technique that could speed up drug discovery and development of therapeutic proteins and vaccines. The electrochemistry-based approach allows for safety and quality testing to be done at a fraction of the time required by conventional methods.
Researchers found no link between R&D costs and high drug prices in the US, contradicting industry claims. Despite $83 billion spent on R&D in 2019, drug prices are driven by market demand rather than investment costs.
Monon Bioventures has received a grant to develop a novel glioblastoma treatment using armed natural killer cells. The treatment, created by Purdue University researcher Sandro Matosevic, shows promise in preclinical proof of concept and aims to manufacture the therapeutic for clinical studies.
Researchers at Kobe University have developed a new method to synthesize fluoroalkyl carbonates, which are environmentally friendly alternatives to toxic precursors. These carbonates exhibit high reactivity and can be used to create pharmaceutical intermediates and other substances.
The Critical Path Institute (C-Path) has established a public-private partnership with the FDA and NIH to advance treatments for rare neurodegenerative diseases. The partnership will leverage C-Path's expertise in data management, quantitative analytics, and regulatory science to accelerate medical product development.
A new mid-infrared sensor chip can accurately monitor liquid concentrations in real-time, enabling precise monitoring of chemical reactions. The sensor combines customized infrared technology and chemical robustness to deliver data within fractions of a second.
New polymer-based membranes developed at KAUST enable greener separation of simple to complex hydrocarbon mixtures, reducing energy consumption and CO2 emissions in crude oil refineries. The membranes' stability and selectivity can be tuned by thermal crosslinking, allowing for higher purity components and removal of byproducts.
A team of Japanese researchers used reinforcement learning to study fluid mixing during laminar flow, achieving exponentially fast mixing without prior knowledge. The method also enabled effective transfer learning, reducing training time for new mixing problems, and has potential applications across various industries.
A team of researchers has identified two compounds that target DNMT3A complexes in cancer cells, offering a safer and more targeted treatment for leukemia patients. The findings provide hope for reducing off-target toxicity associated with current leukemia therapies.
Researchers at KAUST have developed a new type of carbon molecular sieve membrane that overcomes drawbacks of existing polymer membranes. The membrane, made from 6FDA-DMN, exhibits high rejection of small molecules and exceptional stability in various organic solvents.
The workshop will discuss recent advances, perspectives, and applications of medical cannabis and cannabinoids. Researchers will explore their chemistry, pharmacology, analysis, influence on mitochondria, and potential use as anticancer agents.
A multi-national study found that over half of clinical trials leading to FDA-approved anticancer medicines are not available for independent scrutiny. The lack of transparency hinders the use of data for further research into the safety and efficacy of medicines.
Researchers developed a mathematical model to predict the efficiency of nanoparticle delivery into cells, particularly in stem cells. They found that nanoparticles become trapped in bubble-like vesicles, preventing them from reaching their targets.
The CREATE CARES and NTUitive initiative aims to accelerate the development of nanomaterials for various industries, reducing experimental workload and improving quality. The Accelerated Manufacturing Platform for Engineered Nanomaterials (AMPLE) project will utilize Industry 4.0 practices to scale up nanotechnology production.
A new study from the University of Texas at Austin found that companies with high levels of inventor collaboration are better off when collaborating with universities, as it creates a knowledge protection effect. This strategy helps organizations hedge against rivals discovering company secrets while still benefiting from academic part...
A new NJIT-led center aims to tackle complex challenges in drug development, including improved solubility, affordability, and accessibility. Researchers will investigate particle properties and develop digital tools to predict behaviors, enabling more efficient formulations and manufacturing processes.
The UK's Joint Committee on Vaccination and Immunisation advises that COVID vaccines should be offered to 5–11-year-old children, but deem immunization as non-essential. Dr Hamid Merchant explains why current vaccines are not suitable for children due to efficacy and safety concerns.
Researchers at Waseda University demonstrate a novel zirconocene-catalyzed epoxide ring-opening reaction under visible light, expanding the reaction scope and regioselectivity. The approach enables accessible synthesis of elusive alcohol products with improved efficiency and environmental sustainability.
Researchers at Rutgers University have created an automated tool to monitor biologic drugs during production, allowing for real-time quality control and enabling the production of biosimilars. The N-GLYcanyzer system can track changes in protein glycosylation and detect potential issues, improving drug safety and efficacy.
A recent study published in Journal of the American Pharmacists Association found that pharmacists are at a higher risk of suicide compared to the general population, with a rate of 20 per 100,000 pharmacists versus 12 per 100,000 in the general population.
A study found that regular pharmacist visits reduced medicine-related problems by 60% and improved cognition scores. The research highlights the need for personalized pharmaceutical support within the aged-care sector to prevent harm from medicines.
North Carolina State University researchers have developed a faster and less expensive technique for producing hindered amines, a class of chemicals used in various products. The new method uses continuous flow reactor technologies to produce hindered amines within 30 minutes, with minimal byproducts.
More than half of Michigan pharmacies offer naloxone, a life-saving medication for opioid overdose, without requiring a prescription. The standing order allows pharmacists to dispense the drug in emergency situations.
Researchers have successfully visualized crystal nucleation, a crucial stage in crystallization, using Raman microspectroscopy and optical trapping. This breakthrough enables better understanding of molecular dynamics and may lead to the development of purer and more stable crystals for pharmaceuticals and other industries.