Articles tagged with Pharmaceutical Industry
A study found that up to 80% of US medical doctors leading influential professional associations had financial relationships with industry. The largest payments flowed to leaders of the American Society of Clinical Oncology and the American College of Cardiology. Researchers call for policy reform and greater independence from industry.
A recent study published in the Journal of Thoracic Oncology found that lung cancer clinical trials funded by the pharmaceutical industry demonstrate no more bias compared to studies funded by other sources. The analysis, led by Dr. Pedro Aguiar, assessed 477 studies and found that pharmaceutical-backed trials had stronger evidence, ev...
A recent study highlights large gaps in the cannabis genome, with less than 50% accurately mapped and 10-25% unmapped. The research aims to develop a molecular breeding program for cannabis comparable to other crops, with potential applications in human and animal health.
Experts debate nationalizing the pharmaceutical sector to improve public health priorities, address extortionate pricing, and ensure patient access to new advanced drugs. Mariana Mazzucato and Henry Lishi Li propose a government-provided quality-assured medicine option that co-exists with private sector products.
The pharmaceutical and health product industry spent approximately $3.8 billion on lobbying and campaign contributions in the US from 1999 to 2018. This observational study used federal- and state-level data to track the industry's spending over two decades.
The new approach makes the screening process hundreds of times faster and accelerates solvent retrieval. It can determine a solvent's efficiency in as little as three minutes using image processing, running multiple samples simultaneously.
A team of European scientists developed a micro-particle size analyser using AI and consumer electronics. The device measures particle size with precision comparable to commercial light-based analysers, but is much smaller, lighter, and cheaper.
A new method using bubble-attracting sheets of specially textured mesh can significantly reduce or eliminate foamy bubbles in industrial processes. The system works by attracting and shedding bubbles, allowing them to dissipate quickly and reducing the need for chemical additives.
In 2019, the pharmaceutical industry approved 48 new medicines, including treatments for various cancers, sickle cell disease, and migraines. The majority of these drugs had novel mechanisms of action, such as antibody-drug conjugates and small interfering RNA.
A systematic review of observational studies found that industry funding of patient groups is common, with estimates ranging from 20% to 83%. Few patient groups have formal policies governing corporate sponsorship, and financial transparency is inadequate. The researchers call for greater transparency in reporting industry funding and ...
University of Seville researchers successfully printed a 3D image using stabilised gold nanoparticles and biodegradable polymer systems. This breakthrough has significant implications for the pharmaceutical industry, particularly in the development of personalized biosensors.
The American Chemical Society forecasts a year marked by environmental improvements, such as reducing plastic use and recycling. Regulatory actions are also expected, including updated chemical risk assessments and classification of PFAS as hazardous materials.
Researchers have developed a method to produce astaxanthin, a natural antioxidant, in a faster and more efficient way than previous methods. The new process uses the fast-growing marine cyanobacterium Synechococcus sp. PCC7002 as a host and requires only water, light, and CO2 to produce the valuable substance.
Researchers found that particles in microgravity develop strong electrical charges and stick together, forming large aggregates. This process helps explain how asteroids and planets form in outer space. The study also identifies new approaches for controlling fine particle aggregation in industrial processing.
Researchers at Graz University of Technology and Austrian Centre of Industrial Biotechnology have discovered the mechanism behind Apiose production, a key factor in plant robustness. The enzyme UAXS selectively catalyzes four reaction steps, enabling plants to build strength properties.
A new analysis finds that large drug manufacturers would still be the most profitable industry sector even with $1 trillion in lower sales. This is despite the pharmaceutical industry having among the highest profit margins and returns of any industry group. The researchers found that large drug companies could lose significant revenue...
Dr. Martha A. Brumfield, a renowned leader in pharmaceutical development and regulatory science, has been awarded the Jon W. McGarity Arizona Bioscience Leader of the Year honor. Her contributions to accelerating medical product development and building collaborative solutions have significantly benefited patients and their families.
A recent study demonstrates the use of Generative Tensorial Reinforcement Learning (GENTRL) to design and validate a novel drug candidate against fibrosis and cancer. The AI process accelerated the development from 46 days, reducing the time estimate by approximately 94%.
The project, 'Accelerated Innovation in Manufacturing Biologics (AIM-Bio)', aims to develop new manufacturing processes and train a generation of scientists and engineers. NC State will collaborate with DTU to establish nine research projects focusing on technologies critical to biopharmaceutical manufacturing.
Researchers at Indiana University created the first global map of labor flow in collaboration with LinkedIn, revealing skills and industries in high demand across the U.S. and globally. The study also identified growing industries such as pharmaceuticals and oil and gas, while others like retail and telecommunications are declining.
A commentary by UCSF experts highlights the need for radical reform in addressing dental decay, citing the sugar industry's influence on dental research and professional bodies. The authors recommend policies to manage financial conflicts of interest and promote public trust.
Researchers at Insilico Medicine have developed a new molecular descriptor, MCE-18, which estimates molecular complexity and defines the evolution of small molecules in medicinal chemistry. The study reveals that modern drug development is becoming more qualitative and smarter, with higher degrees of 3D complexity.
A recent analysis found that the UK drug industry donated over £57 million to patient organisations between 2012 and 2016. The majority of this funding was directed towards commercially high-profile conditions such as cancer and diabetes, with companies prioritising public involvement, research engagement, and advocacy.
Researchers developed a new fluorescence-based test for Lewis acidity, simplifying existing methods and providing accurate measurements. The innovation could lead to improved and cheaper processes in the pharmaceutical and chemical industries.
An investigation by The BMJ found that many NHS trusts are keeping secret details of their partnerships with drug companies, despite official guidance for transparency. Joint working arrangements between the NHS and industry have spent over £7.5m on projects such as ADHD medication reviews and age-related macular degeneration treatments.
Researchers at Kobe University have successfully produced xylitol and cellulose nanofibers from Kraft pulp using a modified yeast strain that displays enzymes on its cell surface. This breakthrough reduces the need for costly commercial enzymes, making the process more cost-efficient and environmentally friendly.
A new study found that US-based patient advocacy organizations received 74% of total contributions from the world's 10 largest pharmaceutical companies in 2016. The study highlights inconsistent reporting and disclosure across countries, impeding transparency of pharma contributions to patient advocacy groups.
A NYU Tandon team has designed a novel reactor that uses solar energy and plant waste to produce adiponitrile, a precursor material for Nylon production. The technology employs organic electrosynthesis, which can be generated via renewable energy sources like solar or wind power.
Certara has published four peer-reviewed papers on MIPD, outlining the vision and practical path for making individualized dosing a reality. MIPD uses computer modeling to predict optimal drug doses for patients based on their unique characteristics, especially those in vulnerable populations.
Scientists are creating new receptor-molecules and nanostructures to detect and destroy industrial pollutants like pesticides, herbicides, and pharmaceuticals. The goal is to develop a more effective technology for cleaning the environment, addressing a major issue due to the 'chiral' nature of these pollutants.
A study found that increased opioid marketing to physicians was associated with higher prescribing rates and subsequent overdose deaths. The analysis, which analyzed industry marketing data and national opioid prescribing and death data, reported $40 million in targeted marketing efforts across over 2,200 counties.
A new study found that increased marketing of opioid products to physicians is associated with higher opioid prescribing rates and elevated overdose deaths in the US. The research suggests that even low-value payments or subtle marketing tactics can influence physician prescribing patterns, leading to more overdose deaths.
Researchers from the University of Sydney develop a new X-ray method called X-ray rheography, which allows scientists to see flowing grains within opaque materials. The technique uses Sudoku-style puzzle-solving to gather information and has helped uncover unique patterns and waves in granular flows.
Scientists at John Innes Centre and University of Queensland have improved space-inspired speed breeding technique to breed disease-resistant, climate-resilient crops. By using enhanced LED lighting and day-long regimes, they can grow six generations of wheat per year, compared to two generations using traditional breeding methods.
A study by the University of Zurich found that even small gifts can significantly increase sales, particularly when given to the boss. In a controlled experiment, sales representatives gave customers six tubes of toothpaste worth around 10 francs, leading to orders almost twice as high.
A University of Sydney review of corporate influence on research agendas reveals industry prioritization of profitable product-focused research, compromising public health policies. The study also exposes Coca-Cola's attempts to shift attention from sugar-sweetened beverages to sedentary behavior.
Researchers from Ruhr-University Bochum have developed new phosphine ligands that enhance gold catalysts' activity and stability. These findings allow for more efficient reactions at lower temperatures with reduced catalyst quantities, promising economic benefits in industries.
A new study shows that combining machine learning and quantum chemistry can help chemical engineers at Rice University and Penn State find fundamental correlations in large amounts of data. This allows them to narrow down their search and design more efficient catalysts, which can translate into millions of dollars for companies.
A group of 21 physicians published a comprehensive proposal for universal access to safe, innovative, and affordable medications. The plan outlines seven critical areas for reform, including establishing national formularies, negotiating with manufacturers, and increasing transparency in clinical trials.
A study found that nonresearch payments from pharmaceutical industry marketing of opioid products were associated with higher opioid prescribing rates. The research used two U.S databases to identify all nonresearch payments and gather information on opioid prescriptions written by physicians for Medicare beneficiaries in 2015.
A study from Cass Business School reveals that Western Internet Firms (WIFs) fail in China due to cultural and competitive differences. CIFs' use of ancient Chinese military strategies and tactics gave them an advantage in competition, while WIFs' limited understanding of the local market hindered their success.
Professor William Lee's research uses mathematical modeling to investigate topics such as Guinness bubbles and filter coffee machines. His work has led to the development of a mathematical model for coffee brewing that can aid machine design, and he is now exploring the link between strength and flavor in espresso.
Researchers at Tufts University created a genetically modified yeast that can efficiently consume xylose, enabling faster growth and higher cell densities. The new synthetic regulon, dubbed XYL, preserved a natural interaction between feeding and survival genes, leading to improved survival of the xylose-eating yeast organism.
A new study found that medical expansion and increased specialization are associated with longer life expectancy and less mortality, but pharmaceutical industry growth is linked to negative health effects. The study suggests that the growing drug industry may be contributing to the rising costs of healthcare.
A team of researchers has developed a novel reaction to insert nitrogen into C-H bonds, creating useful ring-shaped molecules. The breakthrough synthesis uses inexpensive feedstock hydrocarbons as substrates, offering a new solution to the long-standing challenge in pharmaceutical and chemical industries.
Scientists at University of Limerick are teaming up with Enterprise Ireland to commercialize continuous nanomanufacturing technology. The project aims to tackle the biggest challenge facing the pharmaceutical industry today, which is that seven out of ten drugs never reach patients due to poor solubility.
Researchers at KAUST and TUM have successfully identified and characterized an enzyme from a brine pool in the Red Sea, which shows promising characteristics for commercial use. The study uses single-amplified genomes to produce proteins and provides a roadmap for mining molecular riches of extreme environments.
Clinical commissioning groups in England received over £3.7 million in payments from drug companies that were not disclosed to patients and the public. The findings show that only two-thirds of payments and a quarter of their value were listed in registers or declarations published by CCGs.
The 2017 WRIB White Papers cover topics such as LCMS small molecules, hybrid LBA/LCMS biotherapeutics, and immunogenicity assays. An interactive Decennial Index of the White Papers provides a decade-long overview of recommendations on bioanalysis and biomarkers.
Researchers at RUDN University have developed a way to produce benzofurans, a key component in various pharmaceutical substances, from cheap agricultural and woody waste. The new approach uses salicyl alcohols derived from low-cost chemicals, enabling the creation of new benzofuran-based drug substances.
A study by University of Toronto professors found that approximately half of the editors of influential medical journals received payments from the pharmaceutical and medical device industry in 2014. The authors believe that similar policies for journal editors should be implemented to address conflicts of interest.
The Science/Science Careers' 2017 Top Employers Survey ranked Regeneron the top biopharmaceutical employer, followed by Biogen and Pfizer. The survey received over 6,950 responses from employees in biotechnology, biopharmaceutical, and pharmaceutical companies worldwide.
The Center for Biorenewable Chemicals (CBiRC) at Iowa State University has introduced a new model for developing biorenewable technologies. By identifying 'bioprivileged molecules' with unique properties, researchers aim to create value from biomass and expand the bioproduct horizon beyond petrochemicals.
A research team led by Professor Bhesh Bhandari has discovered that small fat globules can impart stability to cream and give cold butter a softer texture. The breakthrough uses nanoemulsions to create innovative dairy ingredients with potential to increase the return on investment for dairy manufacturers.
The special focus issue of Bioanalysis examines models and trends in outsourcing, featuring insights from key opinion leaders. The issue highlights the rapidly evolving aspect of drug discovery and development.
A new study by UC San Francisco researchers found that tobacco companies knew NRT hardly ever works without counseling, but now sell it over-the-counter to complement smoking. The 'Tobacco Papers' reveal how industry documents show a shift in perception toward nicotine.
Researchers at ETH Zurich have created a new type of silica particle that can stabilize both oil-in-water and water-in-oil emulsions using a single type of emulsifier. The particles' rough surface reduces their mobility, allowing them to form a stabilizing armour around droplets.
Rippleshot uses machine learning and data analytics to detect payment-card fraud, identifying at-risk cards and suggesting counteractions to prevent loss. The Innovate Indiana Fund investment will help expand the company's technical team and product offerings for merchants and banks.
A recent survey found that 65 percent of respondents had visited a physician who accepted industry payments, while only 5 percent knew if their own doctor received such favors. The study highlights the need for greater transparency in medical practices.
A new study found that 65% of patients visited a doctor who received payments from pharmaceutical or medical device companies within the last year. Only 5% of those surveyed knew about their doctor's payments, highlighting a need for transparency and patient awareness.