Articles tagged with Pharmaceutical Industry
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Professor Rasmus Bro receives the first Nils Foss Excellence Prize for his groundbreaking work in process analytical technology (PAT) in the food industry. He has developed methods to analyse complex fluorescence data, revolutionizing water quality measurement.
A new study analyzed industry payments to 8,333 dermatologists in 2014, finding that the top 10% collected at least $3,940 and the top 1% received over $93,622. The majority of payments were for speaker fees, consulting, or research activities.
The John Innes Centre has developed a comprehensive online training hub for wheat researchers, providing essential information on experimental protocols, genomics tools, and cultivation techniques. The platform aims to break down barriers to wheat research, enabling new scientists to transition into the field.
The global seaweed industry is driving growth with valuable uses in food, fertilizer, pharmaceuticals, and industrial products. However, rapid expansion poses ecological and societal risks, including disease outbreaks and environmental degradation.
A study found that nearly nine out of ten physicians and researchers who developed leading cancer care guidelines in the US reported financial ties to the pharmaceutical and medical device industries. The majority of payments were within limits set by the NCCN, but eight guideline authors exceeded them.
Researchers at John Innes Centre discover a key 'twist' in producing heteroyohimbine compounds, which could lead to new and effective pharmaceuticals. The study reveals the importance of specific amino acid sequences in controlling stereoselectivity during compound synthesis.
Researchers have discovered a way to custom-build valuable triterpenes using 'chemical origami', a process inspired by the ancient Japanese art of origami. By modifying an enzyme called SAD1, they can produce different triterpene scaffolds and building blocks, leading to new medicines and industrial chemicals.
The 2016 Blavatnik National Awards recognize David Charbonneau's exoplanet discoveries, Phil Baran's natural product synthesis research, and Michael Rape's fundamental discoveries in ubiquitylation. The three Laureates receive $250,000 cash awards to support their future work.
A study found that physicians who received pharmaceutical industry-sponsored meals were more likely to prescribe certain brand-name drugs, with the rate increasing with the number and cost of meals. The study highlights concerns about the potential influence of industry payments on prescribing patterns.
The National Cell Manufacturing Consortium has developed a national roadmap for advanced cell manufacturing, aiming to increase the production of high-quality living cells for cell-based therapies. The consortium, established by Georgia Tech and industry partners, aims to establish the US as a leader in cell therapy manufacturing.
Researchers at ETH Zurich successfully upgraded methane into methyl bromide, a base material for fuels and chemicals, through oxybromination chemistry. The new catalyst, vanadium phosphate, enables closed-bromine recycling, making the process more efficient and environmentally friendly.
York University researchers have received a $1.7 million grant to develop a platform that rapidly determines detailed information about biologic drug candidates. The project aims to accelerate and improve the quality of pharmaceutical companies' drug discovery and development processes.
Scientists at Scripps Research Institute have developed a new electrochemistry-based method for allylic oxidation reactions, which are used in pharmaceuticals, flavor, and fragrance industries. The new method uses inexpensive, safe chemicals and is scalable, producing better yields and reducing toxic waste.
A new study from the University of Sydney found that medical device and pharmaceutical companies interact with nurses, who have significant influence over hospital purchasing decisions. Nurses reported receiving gifts, product samples, and paid travel, and most acknowledged benefits in working with industry representatives.
Patients undergoing parathyroid surgery experienced fewer hip fractures and fractures of any type compared to those receiving bisphosphonates. Surgery also improved bone mineral density, while bisphosphonates had no impact on fracture risk.
Researchers at RMIT University have developed a method to grow nanostructures that degrade organic matter when exposed to light, directly onto textiles. The technology has the potential to create fully self-cleaning textiles that can spontaneously clean stains and grime with minimal effort.
Researchers from the University of Surrey have discovered a new physical mechanism that separates particles according to their size during the drying of wet coatings. This 'self-layering' process creates two layers with independent properties, which could improve the performance of coatings across industries.
Researchers at the University of Huddersfield have pioneered sugar-powered catalysis, which could revolutionize industries such as agro-chemistry and pharmaceuticals. By harnessing the reducing potential of renewable sugars, scientists have developed a cost-effective and environmentally friendly method for catalysis.
A study by Temple University researchers found that pharmaceutical companies can improve their performance by investing in commercial innovation and aligning their culture of execution. The study, published in the Journal of Medical Marketing, analyzed data from 26 large and medium-sized pharmaceutical companies.
Researchers have developed new humidity sensors with antibacterial properties to prevent biofilm formation and biofouling in high-humidity environments. The sensors combine nanotechnology and fibre optics, offering biocompatibility, low cost, and long-distance measuring capabilities.
The TPP may drive up pharmaceutical prices in low-income countries, diminishing access to essential medications. The agreement also raises concerns about individual country litigation against multi-national pharmaceutical companies.
Researchers at MIT Portugal have created eco-friendly green detergents using biosurfactants derived from lignocellulosic biomass, offering advantages in bio-degradability and non-toxicity. The technology reduces costs of raw materials and environmental impact on production, providing a cleaner alternative for home and industrial use.
The number of NIH-funded trials decreased by 328, while industry-funded trials increased by 1,965, during the period. The total number of newly registered trials increased by 5,410, with industry-funded trials accounting for the majority of growth.
Scientists have identified the 3D structure of iridoid synthase, an enzyme crucial for producing anticancer and antimalarial compounds from plant natural products. The discovery provides insights into the biosynthesis process, shedding light on the unique mechanism used by this enzyme to generate core iridoid structures.
A new study reveals that nearly 1 in 10 healthcare company board positions are held by top academics from renowned medical institutions. These directors receive significant compensation, including annual payments of $193,000 and stock options, posing major individual and institutional conflict of interests.
The MIT, Broad Institute Foundry aims to revolutionize genetic engineering by enabling the rapid design, testing, and fabrication of large sequences of genetic information. The facility collaborates with academic and industrial partners to develop innovative pipeline tools for efficient and precise DNA design.
Researchers at the John Innes Centre found that Euglena gracilis has over 32,000 active protein-encoding genes, significantly more than humans. The single cell algae can produce various natural compounds, including vitamins, essential amino acids, and a sugar polymer with anti-HIV effects.
Researchers at Queensland University of Technology (QUT) have developed a new genetic technique using CRISPR-Cas9 to improve the nutritional value of feed for livestock. The method generates specific yeast that combine protein with digestive enzymes, reducing the need for supplements.
A Maine algal cluster will be formed to capitalize on growing business opportunities in the sustainable energy and food industries. The cluster aims to develop an implementation roadmap to grow the industry and promote a Maine Algae brand.
Yale University chemists have developed a family of new palladium-based catalysts, expected to lower production costs and boost sustainability. These catalysts create a better infrastructure for catalysis, reducing the need for expensive metals.
The pharmaceutical industry's regulatory system is criticized for lacking accountability and being evidence-based, resulting in high NHS costs and inefficient use of technology appraisal work. The Cancer Drugs Fund is also singled out for criticism due to its inequitable allocation of funds and discrimination against other diseases.
Researchers at the Austrian Centre of Industrial Biotechnology successfully produced large quantities of Nootkatone, a natural flavoring substance used in soft drinks and cosmetics. The substance was produced from sugar using genetic engineering in yeast cells, offering an environmentally friendly alternative to chemical synthesis.
The Austrian Centre of Industrial Biotechnology has developed the world's first continuous purification method for recombinant antibodies from clarified CHO cultures. This breakthrough technology is expected to significantly reduce production costs for highly valued drugs, such as cancer treatments and autoimmune disease therapies. The...
A study published in PLOS Medicine found that pharmaceutical industry self-regulation in the UK and Sweden had significant violations, with nearly 20% of cases being serious breaches. The researchers analyzed complaints and rulings to find that charges incurred by companies were a small percentage of annual sales revenue.
Public health scientists receiving funding from companies like Coca-Cola and Mars have also advised on nutritional guidance, raising questions about bias and conflict of interest. Research funded by the sugar industry has been linked to obesity crisis solutions.
A recent study found that the US rate of investment in medical research declined from 2004 to 2012, while global investment increased, especially in Asia. The share of US medical research funding from industry grew from 46% to 58%, favoring biotechnology and pharmaceutical industries.
The pharmaceutical industry has stepped up its efforts to improve access to medicine in developing countries, with many companies introducing innovative access-oriented business models and expanding generic version production. Despite progress, some companies lag behind, including Sanofi and Pfizer, which fell down the rankings signifi...
Scientists from the John Innes Centre are developing a new business concept to revive heritage lines of barley for brewing, offering greater choice and added value to farmers and brewers. The venture aims to provide sustainable production and high-quality malting barley, capitalizing on the demand for unique beer ingredients.
A Roundtable Discussion explores the application of novel toxicology models to predict adverse health effects and environmental exposures. The discussion covers human cell models, high-throughput screening methods, and three-dimensional tissue culture models.
As global poverty rates decrease, new challenges emerge in addressing rising healthcare costs and demands. Hans Rosling argues that verifiable data and statistics are essential for strategic decisions, and innovative solutions like generic drug production can make treatment more affordable for all.
A Purdue study reveals that reducing corn's growing conditions by 2 hours a day can lower its height by 9-10% and reduce stalk diameter by 8-9% while maintaining its seed yield. This technique could enable controlled environment agriculture in mines and caves for growing high-value transgenic crops.
According to a study published in JAMA, approximately 40% of pharmaceutical company board members also held leadership positions at academic medical centers (AMCs), receiving an average compensation of $312,564. This raises concerns about the potential for conflicts of interest between AMC leaders' fiduciary responsibilities and their ...
A recent study by Concordia University suggests that family CEOs may struggle in innovative industries, where constant innovation and adaptability are key. In contrast, traditional industries with a focus on quality and reputation may benefit from family leadership.
Researchers at Fraunhofer-Gesellschaft have developed systems to process large amounts of industrial data, increasing plant availability and reducing energy consumption. By analyzing data in real-time, operators can quickly identify and eliminate disruptions, optimizing production processes.
ScanDrop, developed by Northeastern University professor Tania Konry, is a single instrument that conducts wide range of biological scans in reduced time and cost compared to industry standard equipment. The tool uses ultra-sensitive detection methods and less material to detect biomarkers signaling diseases such as diabetes or cancer.
A new analysis found that industry-sponsored inventions yielded patents and licenses more frequently than federally sponsored ones, with results consistent across technical fields. Industry-funded inventions generated an average of 12.8 forward citations compared to 5.6 for federally sponsored inventions.
A new analysis of 63 animal studies found that industry-sponsored studies had less favorable results than non-industry funded studies. This highlights the role of selective reporting and methodological problems in communicating research findings.
A systematic review found that non-physician clinicians regularly interact with pharmaceutical sales representatives, receiving gifts and samples. Most reported favorable views of these interactions, with some concerns about potential bias and conflict of interest.
John Jelesko, an associate professor of plant pathology and physiology at Virginia Tech, has been recognized as an AAAS Fellow for his distinguished contributions to the field of plant specialized metabolism. His research has led to a better understanding of plant metabolism with significant implications for the pharmaceutical industry.
This year's AAPS Fellows were recognized for their research and scholarly contributions in various fields of pharmaceutical sciences, including immunology, drug delivery, and clinical pharmacology. Notable recipients include Sathy Balu-Iyer, who developed a mechanistic model to understand immunogenicity of biotherapeutics.
A new standard provides confidence that results from handheld Raman spectrometers can be compared accurately. The standard corrects differences in peak intensities reported by different instruments, enabling consistent measurements in emergency response situations.
Despite progress, most US medical schools still lag behind national standards in managing clinical conflicts of interest (CCOI). A new study reveals that institutions are improving, but nearly a third lack policies on industry ties.
The University of Washington is partnering with OceanGate to develop a five-person deep-sea manned submarine that can reach depths of over 9,842 feet. The Cyclops submarine features a carbon-fiber hull and advanced control systems, allowing for increased safety and efficiency in ocean research and exploration.
The American Chemical Society's presidential symposium discusses various career paths for scientists, including academia, business and industry, government, societies and associations, and venture capital. The symposium aims to provide career advancement opportunities for chemists and scientists.
Researchers propose a rigorous evidence-based approach to identify what works and doesn't work in collaborations, aiming to improve the efficiency of drug development. Thousands of organizations have come together in over 100 multi-stakeholder collaborations to solve specific problems.
A new computational technique developed by researchers at the University of Kansas allows industry regulators and consumers to predict whether a given compound will be toxic even at low doses. The method combines QSAR principles with statistical analysis, achieving higher prediction accuracy than previous approaches.
Researchers have discovered a bacterium in South America that produces poly-beta-hydroxybutyrate (PHB), a biodegradable compound used in the food, pharmaceutical, and cosmetic industries. The strain, Bacillus megaterium Uyuni S29, produces large amounts of PHB, making it a promising natural substitute for petroleum-based plastics.
The lack of transparency in clinical trials has been criticized by Ben Goldacre, who calls for the sharing of Clinical Study Reports to ensure informed decisions about medicines. The problem of missing trials is one of the greatest ethical challenges facing medicine today.
The NIH is funding collaborations between academia and industry to explore new uses for existing compounds in eight disease areas, including Alzheimer's disease and schizophrenia. The initiative aims to accelerate the development of new treatments by leveraging existing research and development.
A new report suggests that breaking up the relationship between physicians and drug companies could lead to improved healthcare and cost savings. Researchers from Oregon State University found that avoiding conflicts of interest and replacing industry-funded information with peer-reviewed sources can help physicians make more informed ...