Articles tagged with Discovery Research
Researchers at Rockefeller University have developed a method to trigger a potent immune response in humans using mature dendritic cells, which lasts for months. The technique shows promise as a new way to fight cancers and chronic infections like HIV.
Researchers confirm presence of fullerenes in Allende meteorite, which could have played a role in early Earth's history and origin of life. The discovery provides insights into the formation of the solar nebula and presolar dust.
Coral reefs are experiencing extensive bleaching due to gradual warming of ocean temperatures. A new study found that heat damage to symbiotic algae is degrading their ability to convert light into utilizable energy. The damaged algae, including the D1 protein, impair photosynthesis and lead to coral expulsion.
A study found that pine cones' spines hinder finches' ability to access seeds, encouraging seed dispersal. Researchers discovered a link between spine growth and the length of time seeds remain on pine cones.
Researchers at USC and UC Irvine have discovered two independent brain pathways that process visual information, highlighting the importance of integrating color and motion. The 'Third Order' system is found to be critical for detecting pure color motion, allowing humans to perceive movement in 'isoluminant' images.
Researchers developed a method to identify high-risk individuals with Parkinson's disease using SPECT brain imaging and beta CIT radiopharmaceutical. They differentiated between Parkinson's patients and controls, as well as relatives of Parkinson's patients, with reduced drug binding.
Researchers have identified principles for insect flight that will help design and construct tiny robotic flies. The Micromechanical Flying Insect project aims to develop a robotic fly that can fly short distances and maintain stable hover
Researchers have successfully eliminated human brain tumors grown in mice using a toxin produced by E. coli bacteria, providing a potential breakthrough in treating astrocytoma and glioblastoma, two common types of brain cancer. The next phase of research will focus on preliminary clinical trials in older children and adults.
A new species of deer, the leaf deer, has been identified in remote mountain regions of Southeast Asia. The species was confirmed through DNA sequencing and represents a significant discovery in conservation biology.
A team of scientists has found a critical interaction between two brain proteins that could help explain the death of nerve cells in Alzheimer's disease. The discovery reveals that normal APP provides a protective function against cell death, while mutant forms do not.
A team of researchers from Case Western Reserve University has discovered a new species of human ancestor, Australopithecus garhi, in the Afar Desert of Ethiopia. The fossils, dated to 2.5 million years ago, exhibit a unique combination of traits that were unexpected and fill a major gap in our understanding of human evolution.
Researchers discovered oscillations in individual heart cells causing beat-to-beat alternations, leading to fibrillation and death. A new test highlights this pattern for easier detection, potentially saving thousands of lives annually from sudden cardiac arrest.
Researchers from the University of Iowa have identified a feedback loop mechanism that could explain the prolonged nature of migraines. The discovery reveals that inflammatory agents released during a migraine stimulate certain neurons to increase calcitonin gene-related peptides (CGRP) secretion, leading to persistent pain.
A newly discovered gene family, Morc, regulates important biological processes and may play a role in cell division in all tissues. The researchers also believe that the Morc family members may malfunction in cancer cells.
Researchers used the One-Ångstrom Microscope to create unprecedented images of columns of carbon atoms in diamond lattices and nitrogen atoms in gallium nitride at atomic resolution. The technique overcomes challenges of resolving light elements in crystal lattices, enabling new discoveries in superhard materials, high-temperature supe...
Researchers found a protein called GON-1 that regulates organ shape in Caenorhabditis elegans, a microscopic worm. This discovery could lead to the development of inhibitors to slow or stop cancer cell spread and may one day enable growing human organs in labs.
Researchers at Lawrence Berkeley National Laboratory have discovered two new superheavy elements, 116 and 118, using an intense beam of high-energy krypton ions. The discovery was made possible by the newly constructed Berkeley Gas-filled Separator, which allows for unprecedented efficiency and background suppression.
Dr. Colleen Wilson-Hodge, a NASA astrophysicist, has discovered two new X-ray pulsars using the Burst and Transient Source Experiment on NASA's Compton Gamma Ray Observatory. The pulsars are powered by accretion of material from companion stars and have strong gravity that pulls matter toward their surfaces.
The first 3D topographic images of the lunar polar regions have been revealed by Cornell University researchers, indicating potential sites for water ice deposits. The new images obtained through radar interferometry show five large craters in the south polar region that could contain significant amounts of water ice.
Researchers have found evidence of chlorine emissions in the atmosphere of Io, a Jupiter moon with high volcanic activity. The discovery suggests that salt may be present on Io's surface due to chemical reactions or geological processes.
Researchers have found surprising variation in nicotine withdrawal symptoms, with many experiencing intense spikes months after quitting. The study suggests that the duration or pattern of withdrawal symptoms is more difficult to overcome than the initial intensity.
A team of astronomers has discovered a unique cluster of young stars, approximately 8 million years old, located 97 parsecs from Earth. The cluster, centered around eta Chamaeleon, is one of the nearest to our planet and exhibits unusual characteristics.
Researchers at Schering-Plough Research Institute have made the first atomic view of a promising new class of cancer-fighting drugs. The discovery may lead to faster, better refinement of the drugs and the development of more potent, less toxic treatments.
Scientists at University of Wisconsin-Madison uncover new process to produce lovastatin, a natural substance that lowers cholesterol in humans. The discovery may lead to more potent and affordable drugs through genetic engineering.
Researchers at University of North Carolina at Chapel Hill and Rockefeller University have discovered that mammalian chromosomes end in loops, also known as telomeres. This finding has significant implications for our understanding of cell aging and cancer, providing a new way to think about molecular mechanisms.
Scientists discover cytosolic catalase enzyme protects cells from oxidative damage in long-lived worms, offering insight into aging process and potential therapy for nervous system diseases. The study suggests that increasing cellular health through antioxidant measures could extend lifespan, rather than relying on genetic regulation.
Rockefeller University scientists Dr. Arnold J. Levine and Dr. Robert G. Roeder have been recognized by the General Motors Cancer Research Foundation for their groundbreaking work on cancer research and gene transcription. Their discoveries are paving the way for new diagnostics and therapies, with p53 abnormalities associated with ove...
A research team at MGH and Harvard University identified a molecule called TRP2 that may play a crucial role in the process of converting chemical signals into nerve impulses in rats. This discovery suggests that humans might process pheromones through a different mechanism than most other mammals.
Researchers at Cedars-Sinai Medical Center have made two groundbreaking discoveries. Firstly, they found that magnesium boosts cell proliferation in neural cells, potentially revolutionizing neural development. Secondly, a study identified a key receptor in human cells that may contribute to septic shock's immune response, offering new...
Researchers are investigating the role of cyclic ADP-ribose (cADPR) in cell death pathways associated with oxidative stress, including heart attack, stroke, and cancer. The study aims to identify proteins that synthesize cADPR and develop new therapeutic agents to treat these diseases.
Rudolph's application of physiology to congenital heart disease significantly advanced understanding of normal and abnormal heart development in newborn humans. His research led to the development of new diagnostic and treatment methods for congenital heart defects.
The discovery of Australopithecus garhi provides crucial information about the evolution of humans, revealing a species that walked on human-like legs and used stone tools to strip meat from bones. The fossils also suggest that this species may have been the immediate predecessor of humans.
Researchers at the University of Toronto have discovered a 50-million-year-old association between an antibiotic-producing bacterium and fungus-growing ants. The study suggests that this symbiotic relationship may provide valuable new insights into the identification, production, and use of antibiotics.
Researchers discovered that mammalian support cells can proliferate when an enzyme inhibitor is absent, paving the way for potential hair-cell regeneration. This breakthrough offers hope for restoring hearing in humans and other mammals who suffer from noise-induced hearing loss.
The 90th Annual Meeting of American Association for Cancer Research will showcase groundbreaking research in translational cancer research, including anti-angiogenesis agents, cancer vaccines, gene therapy, and molecular targeted therapy. The meeting will feature over 5,000 abstracts and 200 invited presentations from leading experts.
Researchers at the University of Michigan discovered that folic acid effectively lowers homocysteine levels in blood plasma, reducing the risk of heart attacks and strokes. The study found that folic acid supplementation can also benefit people with normal MTHFR enzymes by protecting them against heat-induced enzyme inactivation.
Researchers at De Montfort University discovered a porous version of silicon with potential for biocompatibility, allowing for the transmission of signals between mechanical devices and human tissue. This breakthrough could lead to innovative applications in sensing and prosthetics.
Beta catenin disrupts cell regulation by synthesizing cyclin D1, allowing cells to proliferate out of control. The finding offers a potential new target for drug therapy in colon and other cancers.
Researchers create microscopic patterns on surfaces using microcontact printing, then build up layers of a polymer material over the pattern. The technique enables complex pattern creation and automation of the patterning process.
Researchers at Cornell University have developed a technique to grow pure, defect-free single crystals of almost any material on any substrate by bonding thin films at a misaligned angle. The new method has the potential to revolutionize electronics manufacturing by overcoming current limitations.
Researchers have identified a receptor protein in rodents and humans that can detect temperatures above 120 degrees Fahrenheit, expanding the range of temperatures for which nerve receptors are known. The discovery holds promise for better understanding pain and developing drugs to block pain.
Scientists have developed a new method to study sprites, the high-altitude companions of lightning strikes, using radio signals. By analyzing these signals, researchers can now estimate the number of sprites spawned by a single thunderstorm with greater accuracy.
A new way to immunize against the Pseudomonas aeruginosa bacterium has been developed, providing a fresh alternative to antibiotics in fighting this deadly microbe. The antibody blocks the toxin delivery system, allowing lung cells to mount a defense and prevent delivery of toxins.
A recent study found that women's social support is more effective than men's in reducing both men's and women's blood pressure under stress. The researchers discovered that female listeners provided a modest systolic blood pressure increase of 25mmHg, while male listeners caused an average increase of 32mmHg.
Researchers found that estrogen activates neurotransmitter receptors, increasing neuronal activity and long-term potentiation, a process linked to memory and cognitive function. The study suggests estrogen may play a key role in delaying the onset of Alzheimer's disease.
Researchers at UCSF discovered a molecular trigger that initiates uncontrolled mucus production, affecting millions worldwide. They suggest targeting this messenger to develop strategies to control mucus production and prevent airway blockage.
Duke University researchers found that angiostatin works by depleting the chemical energy needed for blood vessel cells to grow. This discovery offers a novel insight into the body's use of ATPsynthase as a power pack and suggests a new route to developing drugs to block tumor growth.
Researchers at Weizmann Institute identify protein IL-18BP, which blocks production of interferon-gamma in T cells, a major substance released by immune cells under the influence of interleukin 18. This discovery may lead to new treatments for autoimmune diseases and organ transplants.
Researchers discover a gene, mahogany, that regulates obesity in mice, linking it to the immune system. The protein, made inside cells, passes through membranes to detect hormones, potentially leading to new treatment options for obesity.
Scientists at Georgia Tech create a device that can accurately measure the mass of small particles by inducing resonance in individual carbon nanotubes. This technique has potential for weighing viruses and other sub-micron scale particles.
Researchers discovered a genetic mutation responsible for a rare form of treatable dwarfism, affecting 105 family members in northeastern Brazil. The study suggests the mutation could be used as a prenatal screening test for the disorder.
A new chemical sequence has been uncovered, casting doubt on long-held equilibrium theory and clearing the way for kinetic chemistry. The finding breaks the strong bond between carbon and oxygen atoms under intense radioactivity conditions.
Researchers found that snakes use vision to locate places and rely on visual cues to escape a maze-like arena. Younger snakes are more adaptable, while older ones focus on visual cues.
Research reveals that the AIDS virus in cerebrospinal fluid evolves independently of the virus in the blood, leading to two genetically distinct forms. This finding suggests that drugs effective against HIV-1 in blood may not be effective in the central nervous system, and vice versa.
The discovery of the Hephaestin gene offers insight into a cause of iron-deficiency anemia, revealing an intimate relationship between copper and iron metabolism. The protein facilitates transport of iron from the intestines to the body's circulatory system.
University of Pittsburgh researchers isolated bone-precursor cells from skeletal muscle and genetically altered them to produce bone growth. Injecting these cells into mice showed they could form bone inside the animals. This discovery may lead to targeted treatments for incomplete fractures.
Marie Filbin's research discovery reveals a way to overcome the inhibiting function of MAG and other molecules that prevent axon regrowth after injury. By priming neurons with neurotrophins, she reverses inhibition and enables regeneration.
Dr. Keith Wailoo, a UNC associate professor, has been awarded a $1 million James S. McDonnell Centennial Fellowship to study disease and biomedicine in the 20th century. He will investigate how people's ideas about illnesses like breast cancer and sickle cell anemia have changed over time.
Scientists have discovered that laboratory rats fed soy meal develop less pain after nerve injury than those on a soy-free diet. The research suggests that diet could be an important factor in the expression of nerve-injury pain in rats, and may offer possibilities for understanding individual differences in pain perception.
Researchers discovered a link between the dopamine transporter gene (SLC6A3-9) and cigarette smoking behavior. Individuals carrying this gene were less likely to start smoking before age 16 and more likely to quit smoking, with an average of one and a half times greater success rate.