Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have identified a gene, CBFA1, essential for bone-forming cells to arise in the embryo. Disruption of this gene causes cleidocranial dysplasia, a developmental disorder that stunts bone growth.
University of Pennsylvania researchers discover three-dimensional atomic structure of vancomycin using X-ray diffraction analysis. The advance provides detailed knowledge about the vancomycin molecule to help design new antibiotics effective against vancomycin-resistant bacteria.
A recent NIH study suggests that a significant number of people, particularly those with a specific genetic variant, may require increased folate intake to compensate for their genetic deficiency. This finding has implications for the recommended daily allowance and may lead to reviews of dietary reference values.
Scientists have identified a new factor regulating lymphatic vessel growth, which may lead to ways of repairing damaged vessels and better understanding of certain types of cancer. The discovery of VEGF-C could also improve healing after lymph node removal in breast cancer surgery or prevent tumors affecting the lymphatic system.
Darrel Snyder's expertise helps state and federal agencies monitor and bolster populations of threatened species by identifying days-old fish. He has confirmed spawning sites for endangered razorback sucker and Colorado squawfish, providing crucial clues for their survival.
Researchers at UPMC and Carnegie Mellon University identified brain regions responsible for learning through subconscious awareness, potentially impacting disorders like OCD and addiction. This discovery may reveal a new perspective on how the brain learns and adapts to change.
Research reveals grapefruit juice increases CYP3A4 enzyme levels, affecting drug metabolism; this finding narrows the search for responsible substance, enabling safer medications. Consistency is key: individuals taking affected drugs should consult physicians if adding grapefruit juice to their diet.
Researchers have found that penguins from the Punta Tombo reserve in southern Argentina travel more than 300 miles to find food, a significant increase from previously thought foraging ranges. The depletion of squid and other preferred foods is attributed to commercial fisheries and climate change.
Preeclampsia occurs when cytotrophoblasts fail to invade the uterine wall and mimic blood vessel cells, leading to high blood pressure and potential complications. Early detection through testing could save lives and prevent birth defects.
Scientists found that both drugs stimulate release of glutamate, triggering brain cell activity to control mood swings in bipolar disorder. This additive effect may explain the clinical observation that using two drugs together produces better results.
Researchers have identified a key protein in the telomerase enzyme that is selectively activated in many cancer cells. The discovery may lead to the development of new anti-cancer agents, including variants of existing pharmaceuticals.
Researchers from Northwestern University demonstrate a robot called Scooter that is programmed to refuse to go past a virtual surface. This innovation is part of a new class of collaborative robots called cobots, which are designed to work with humans safely and efficiently.
Researchers found significant brain tissue loss in individuals with bipolar and unipolar depression, which may help understand the causes of mood disorders. The study's findings provide new information for developing more effective treatments.
The NIH team identified the MEN1 gene, a tumor suppressor gene that inhibits abnormal cell growth. This discovery enables easier screening for families at risk of MEN1 and provides a target for designing drugs to prevent or treat endocrine tumors.
Researchers at University at Buffalo demonstrate strongest evidence yet for reentrant superconductivity, a phenomenon where magnetic fields enhance superconductivity rather than destroy it. The findings have potential practical applications in energy storage and magnetic resonance imaging.
Researchers at Johns Hopkins have modified established drugs to stimulate nerve growth without suppressing the immune system, a critical step toward treating neurodegenerative diseases. The new compounds were able to regenerate lost branches of nerve cells and cause recovery of functions in lab animals.
Researchers found that black children are nearly 2.5 times more likely than white children to receive hemodialysis versus peritoneal dialysis. The disparity was observed across different age groups, with younger black children being most likely to opt for hemodialysis.
A team of geophysicists has found a partially molten granite pool beneath southwestern Tibet, which could have absorbed India's impact and lifted the plateau. The discovery uses seismic profiling techniques to detect deep earth structures and suggests that the Indian subcontinent's thrust into Asia may have created this zone.
Research on nematodes led to the discovery of potential anti-cancer drugs and antibiotics. The substances, called xenorxides, have proven more effective than traditional anti-cancer drugs in some test settings.
Researchers at Brown University have discovered a novel method for delivering drugs orally using tiny, biocompatible beads that stick to intestinal tissues and slowly erode to release drugs. The technique has shown promise in treating inflammatory bowel disorders such as ulcerative colitis and Crohn's disease.
Researchers at Indiana University launched a full-scale expedition to explore ancient Taino Indian sites in the Dominican Republic. The underwater site has yielded over two dozen artifacts, providing valuable information about the tribe's culture and interactions with Europeans.
Researchers visualize calcium stored deep within intact muscle and brain cells, discovering tiny, discrete compartments that can be opened or closed by drugs or natural chemicals. This finding could lead to a better understanding of physiological mechanisms underlying high blood pressure, heart failure, stroke, and aging.
A recent report from SPRU reveals that British companies are making significant contributions to scientific research, publishing over 41,000 articles between 1981 and 1994. This has led to a reevaluation of the role of industry in advancing science, with findings suggesting that companies are driving innovation across various sectors.
Researchers have discovered that different strains of HIV may exploit distinct immune cells through chemokine coreceptors, potentially explaining the sudden collapse of the immune system in full-blown AIDS patients. The findings could lead to new treatments by targeting these receptors.
Researchers at Stanford University have developed a process to make polypropylene, a stiff plastic, that can flex like a rubber band. The elastic polymer has potential applications in various industries, including the production of disposable diapers and automotive dashboards.
Most young molecular biologists (91%) are satisfied with their career choice despite facing challenges in the field. They believe effective gene therapy and a cure for AIDS will be significant breakthroughs in the next decade.
At the Seattle Science Meeting, USGS researchers will present on various topics including Martian exploration, integrated watershed studies, and geochemical backgrounds in Alaska and the Pacific Northwest. The meeting features several presentations by renowned scientists, including Dr. Michael Carr and Dr. David Howell.
Scientists at Stanford University have developed a system to work with millions of cell-sized squares composed of artificial membranes, offering new possibilities for experiments. The micro-membranes are stable, isolated, and retain their properties for several weeks, making them suitable for applications such as determining the struct...
A new research program using Arabidopsis as a model aims to improve plant branching patterns through DNA manipulation. This could lead to higher-quality wood and reduced harvesting time for eucalyptus and poplar trees, benefiting the paper and construction sectors.
A recent study reveals that in 24 out of 28 cases involving Americans released from prison based on DNA evidence, eyewitnesses made false identifications from photo spreads and lineups. New research is helping to understand the circumstances leading to these errors and find ways to reduce their occurrences.
A new study predicts prostate cancer up to six years earlier than current methods by analyzing the ratio of free to total prostate-specific antigen (PSA) in a man's blood. The research, published in 1996, showed that men with high total PSA levels may have prostate cancer or benign prostatic hypertrophy.
Yale University has granted an exclusive license to ArQule Inc. for the development of patent-pending discoveries that could help fight various diseases, including AIDS and emphysema. The Yale chemists' method allows rapid synthesis of alpha-ketoamide-based compounds, which have shown potential in blocking key enzymes called proteases.
Researchers discovered a genetic mutation in the TIE-2 gene responsible for venous malformations, the most common type of birthmark. The mutation disrupts the normal molecular dialog between endothelial cells and their environment, leading to abnormal blood vessel formation.
Researchers at University of Rochester and NIH discover new HAT that plays critical role in transcription, providing strong evidence for chromatin-unfolding mechanism of gene activation. The finding has significant implications for understanding cell survival, proper development, and evolution.
A new University of North Carolina at Chapel Hill study reveals that women with non-ischemic heart failure have a significantly higher survival rate than men, even after accounting for differences in age and other factors. In contrast, men with ischemic heart failure were more likely to die prematurely.
A multinational team of researchers, led by Syracuse University's K. Douglas Nelson, has discovered a partially molten crust beneath the Himalaya and Tibetan Plateau using seismic reflection and other techniques. This finding challenges traditional views of plate tectonics and may explain the flatness of the Tibetan Plateau.
Scientists have discovered that randomness in lubricants is a major contributor to friction at the molecular level. This finding could lead to reduced wear and tear on machinery. By understanding how lubricants fracture and heal, researchers may develop new methods to control friction and minimize wear.
A UC Davis researcher has discovered that damage to the insula region is a crucial impediment to motor control necessary for words and sentences. The insula, located deep within each hemisphere, is about two inches wide and contains a small area critical for coordinating speech sounds.
Scientists have identified a major gene, HPC-1, that predisposes men to prostate cancer, located on chromosome 1. The gene is believed to contribute to at least a third of familial prostate cancer cases.
Scientists at the University of Georgia have discovered a three-dimensional structure of a fluorescent protein found in jellyfish that resembles a glowing green lantern. This discovery could help make it easier to use the protein as a biomarker for studying gene expression and cell lineage.
Researchers localized the gene responsible for Parkinson's disease to a small region of chromosome 4, marking a significant advancement in understanding the disease. This finding is based on a large family study with multiple cases of Parkinson's disease over several generations.
A new technique called laser capture microdissection enables researchers to extract and analyze small clusters of cells from tissue samples in as little as eight seconds. This allows for immediate analysis of gene and enzyme activity, revolutionizing the understanding of cancer's molecular basis.
Scientists have identified a human protein that allows herpes simplex virus to penetrate into lymphocytes, a key step in understanding recurrent herpetic disease. This breakthrough discovery may lead to the development of new classes of antiviral drugs.
Researchers discover native weevil that targets Eurasian watermilfoil, slowing growth and potentially providing a natural control method. The weevil lays eggs on the plant's tips, which hatch and eat their way through the stem, reducing milfoil's spread.
Scientists have discovered a gene in rye that enables wheat to resist toxins in aluminum often found in acid soils. This breakthrough has the potential to increase wheat yields worldwide, particularly in regions where millions of acres are currently unsuitable for cultivation due to acidic soil conditions.
A newly discovered gene, MAD2, acts as a checkpoint in the cell cycle, ensuring chromosomes are ready to separate properly before cell division. Blocking the gene's activity can lead to tumor growth due to haphazard cell division and missing chromosomes.
The Variegated Glacier surged hundreds of yards by the end of summer, surprising scientists with an early start. Researchers believe the glacier will follow similar surge-and-rest patterns in the future.
Researchers have developed software that can analyze ion-channel activity with remarkable efficiency and speed, enabling researchers to discover key information about protein structures and behavior. This breakthrough has the potential to improve our understanding of genetic diseases such as cystic fibrosis and neuromuscular disorders.
Scientists have discovered a unique organelle-like structure, dubbed the dumposome, which breaks down 15-20% of an organism's DNA during reproduction. This process is thought to be essential for streamlining genetic material and may be more common in other organisms than previously thought.
Breast-cancer researchers at the University of Illinois have identified four critical amino acids in the binding of estrogen and anti-estrogen hormones to receptor proteins. This discovery may lead to the development of more tissue-selective therapies for breast cancer treatment, addressing resistance to current treatments like tamoxifen.
Researchers from Harvard University and Duke Comprehensive Cancer Center discovered a protein called RGS10 that turns off G proteins, which transmit chemical signals within cells. This finding may lead to new ways to regulate cell activity and treat conditions like cancer, heart disease, and neurological disorders.
Tiny laboratory tornadoes may hold clues to detecting tornadoes earlier, a potential breakthrough in warning systems. Researchers have discovered an inverse relationship between vortex size and sound wave frequency.
Researchers have identified a second gene associated with hereditary multiple exostoses, a rare bone disorder characterized by the proliferation of benign tumors. The discovery provides insight into the disease's causes and potential tumor suppressor function.
A CU-Boulder research team has identified two yeast genes, SAS2 and SAS3, closely linked to a family of human genes associated with severe leukemia and HIV-1. The discovery may help researchers better understand the causes of acute myeloid leukemia and AIDS.
Researchers at Eli Lilly have discovered a new pathway through which estrogen affects various organs, including the bones and cardiovascular system. The study provides a potential explanation for how estrogen regulates body functions in different tissues.
A biological 'switch' has been discovered in plants that controls their leaf movements, opening them at dawn and closing them at dusk. This discovery could lead to new applications such as preventing crop wilting during drought or altering the time of flowering.
The USDA has developed Z-Trim, a low-cost agricultural byproduct-based fat substitute with a smooth mouth feel. It can supply important texture qualities in foods like cheese products and baked goods, reducing calories by up to 700 per day.
Researchers at the University of Washington have created a genetic mutation in mice that prevents them from storing fat even on a high-fat diet. The study suggests a potential new approach for treating obesity by targeting the cells' internal signaling pathways.
Researchers investigated nausea in a study of 1,695 Penn State students, discovering 17 descriptors that define the feelings associated with nausea. These descriptors were clustered into three groups: somatic, gastrointestinal, and emotional distress, highlighting the variability in nausea experiences among individuals.
Researchers found that some algal cells can grow and survive in near-normal conditions without Photosystem I, a key component of traditional photosynthesis. This discovery may challenge our understanding of plant biology and suggest new avenues for studying photosynthesis.