Articles tagged with Discovery Research
The Ontario Institute for Cancer Research has announced support for five research teams developing new cancer drugs with improved efficacy and reduced side effects. The funded projects will focus on harnessing new insights about cancer biology to stop cancer from spreading and overcome treatment resistance.
Dr. Leanne Redman, a leading authority on body weight regulation, has received the prestigious E.V. McCollum Award for her translational research on maternal nutrition and energy regulation, with significant impact on public health. The award recognizes her dedication to advancing research that improves women's and families' health.
A research team has identified a previously unknown defense mechanism in Pseudomonas syringae, enabling the bacterium to produce chemical compounds that attract amoebae, which are then killed by toxic substances produced by the bacteria. This 'chemical radar' system also helps the bacteria infect plants in the presence of predators.
The Human Frontier Science Program has awarded 2025 Research Grants and Accelerator Awards to 104 of the world's most innovative scientists, spanning 30 nations. The grants support research on epigenetics, tick-borne diseases, and other life science topics.
A new study by McGill University researchers sheds light on the disruption of calcium transport in the brain's AMPA receptors, linking it to autism and intellectual disability. The findings could pave the way for treatments targeting these receptors, offering hope for patients with related neurological disorders.
Researchers at UTA uncovered how the flowerpot snake repairs its DNA and prevents harmful mutations, shedding light on genetic repair mechanisms that could deepen our understanding of human gene evolution. The study also reveals surprising findings about reproductive strategies and immune-related genes in reptiles.
Researchers have discovered a protective cloaking mechanism in jumbo phages that shield their genetic material from the host's immune system. This innovation could lead to new therapies for antibiotic-resistant infections.
Researchers have developed a new approach to personalize treatments for young cancer patients by growing tumors in chicken eggs and analyzing proteins. The technique, which combines genomics and proteomics, was successful in identifying a treatment option for a patient with a rare pediatric cancer.
A team of chemists from Virginia Tech found a way to visualize the intricate structure and chemical reactions of battery interfaces using an X-ray beam line. This breakthrough enables researchers to gain better control over these critical surfaces, potentially leading to cheaper, higher performance batteries.
Researchers discovered senolytics can target Alzheimer's disease-associated brain enzymes AChE and BChE without affecting healthy ones. This selective approach may lead to safer treatments that improve memory and reduce inflammation in older adults.
A novel AI-based method called scNET combines gene expression data with networks of possible gene interactions to identify biological patterns in response to drug treatments. The system reveals complex mechanisms underlying cellular behavior, providing insights for new therapeutic approaches.
The UK public considers the mobile phone the second most important invention of all time, with 52% viewing it as indispensable. Meanwhile, the wheel tops the list at 31%, ahead of electricity and penicillin.
Researchers Schmidt and Selvin will explore the connections between cardiovascular disease and diabetes, with a focus on large white blood cells and wearable continuous glucose monitors. Their work aims to develop new treatment therapies and improve health outcomes for people with diabetes.
A preclinical study found that linoleic acid, an omega-6 fatty acid, activates a major growth pathway in tumor cells, particularly in triple-negative breast cancer subtypes. A high-linoleic-acid diet enhanced tumor growth in mice with triple-negative breast cancer.
Recent technological advancements have expanded understanding of oceanic mesoscale eddies, regulating ocean energy distribution and material transport processes. The researchers identified four potential hotspots for future research, including eddy stability and air-sea interactions.
The University of Rochester's Wilmot Cancer Institute has been named the nation's 73rd designated cancer center by the National Cancer Institute. This prestigious designation recognizes the institute's excellence in cancer research, patient care, and community outreach.
A University of Minnesota Medical School study identified a key heart marker predicting ischemic stroke and dementia, which could lead to improved patient outcomes. The left atrium's ability to stretch was found to be the most accurate predictor.
Jennifer L. West, UVA Engineering Dean and Saunders Family Professor of Engineering, has been awarded the 2025 Pierre Galletti Award for her innovative research in biomaterials and nanomedicine. Her work has led to breakthroughs in treating cancer with precision, offering new hope to patients battling hard-to-treat cancers.
New research reveals mammals were shifting toward a more ground-based lifestyle several million years before the dinosaurs' mass extinction event. Analyzing small-fossilized bone fragments, scientists found signs of locomotory habit in end of limb bones from marsupial and placental mammals.
A USC Stem Cell mouse study has identified shared genes involved in regenerating cells in the ear and eye, which could lead to new treatments for hearing and vision loss. The researchers discovered that inhibiting a specific protein, p27Kip1, can encourage regeneration in both organs.
Researchers at UCalgary have discovered a protein called CD2AP that may hold the key to reducing Alzheimer's disease risk. Levels of this protein are lower in patients with AD, and its absence affects memory function, particularly in males. The study suggests a sex-dependent link between vascular system health and brain function.
All articles with at least one author based in Africa can now be submitted to the platform and will no longer require funding from a partnering research funder. This expansion aims to increase publication efficiency and improve the experience of African authors, while promoting the rapid sharing and discovery of high-quality research.
A study suggests that children were involved in creating prehistoric cave art due to their unique mental and cognitive traits, which allowed them to communicate with entities from the beyond. Children were believed to be liminal beings, bridging the gap between worlds, and delivering messages to non-human entities.
Cells dynamically adjust nuclear pore complexes like a retail store opening more checkout lines to regulate genome access. Research findings suggest that protein creation and disposal systems control the amount of NPCs in cells.
A recent study identified a quasi-conversion reaction on the cathode surface during discharging, leading to accelerated battery degradation. High nickel content exacerbates this effect.
Researchers developed new AI models, InstaNovo and InstaNovo+, to vastly improve accuracy and discovery in protein science. These models excel in tasks such as de novo peptide sequencing, identifying microorganisms, and discovering novel peptides, with implications for personalized medicine, cancer immunology, and beyond.
A team of scientists discovered a method to produce a stable and conductive bioelectric material without the need for a chemical crosslinker. The new process uses high heat to stabilize the material, producing devices with three times higher electrical conductivity and more consistent stability.
In extremely thin films of niobium diselenide (NbSe₂), superconductivity becomes confined to the surface when thinner than six atomic layers. This discovery challenges previous theories and could have important implications for understanding superconductivity and developing advanced quantum technologies.
Researchers have discovered that common anticancer drugs can reduce vascular growth in patients with PTEN Hamartoma Tumour Syndrome, offering new hope for treatment. These findings were made possible by the development of a mouse model and clinical trials using rapamycin and capivasertib inhibitors.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
A complete Quina technological system, used for making tools, was discovered in southwest China dating back 50,000 to 60,000 years. This finding disputes the widely held belief that development in China was sluggish during most of the Paleolithic period.
The ALL ALS Consortium has recruited over 300 participants across two studies, ASSESS and PREVENT, aiming to disrupt traditional ALS research by making data and samples available worldwide. The consortium seeks to discover new drug targets and approaches for effective treatments.
William Murphy, a genomicist at Texas A&M University, was named the 2025 SEC Professor of the Year. He studies genome structure, function and evolution to understand genetic basis of species traits and diseases.
The University of Malaga will coordinate an international consortium, 'X-SeeO2', aiming to hasten the use of cements as carbon dioxide sinks. The €4 million project aims to reduce CO2 emissions and promote the circular economy by upcycling waste.
The Endocrine Society expresses concern over the administration's plan to reorganize HHS, slashing federal funding and staff, which will hinder medical discoveries and approve new treatments. The society warns that politicization of scientific grants will harm millions of people needing medical care for endocrine conditions.
Researchers at Karolinska Institutet have developed a new method to diagnose COPD by analyzing protein levels in nasal lavage. The study found that elevated IL-26 levels can indicate an early phase of the disease, and may lead to new treatment strategies targeting this cytokine.
The American College of Cardiology is recognizing five primary authors with the William W. Parmley Young Author Achievement Award for their exceptional research papers published in JACC. The award highlights remarkable first-author publications by trainees in JACC and aims to elevate trainee-led research in the journal.
Dr. Rita Okoroafor's research integrates geochemistry, geomechanics, and reservoir engineering to improve understanding of fluid-rock interactions in subsurface technologies. Her work enhances hydrogen storage efficiency, optimizes geothermal reservoir performance, and improves CO2 storage security.
Four UT faculty members, Albrecht von Arnim, Alison Buchan, Susan Kalisz, and David White, were honored as AAAS Lifetime Fellows for their pioneering research in protein synthesis, marine microbes, and biogeochemical cycles. Their work has significant implications for agriculture, nutrition, and the environment.
A team of researchers has developed a groundbreaking high-temperature copper alloy with exceptional thermal stability and mechanical strength. The novel bulk Cu-3Ta-0.5Li nanocrystalline alloy exhibits remarkable resistance to coarsening and creep deformation, even at temperatures near its melting point.
Dr. Bing Ren, a renowned expert in genomics and epigenetics, joins the New York Genome Center as its new scientific director and CEO. His groundbreaking contributions will focus on translating genomic research into actionable insights for improving human health.
The Protein Society recognizes five award winners in 2025 for their groundbreaking research in protein science and technology. Professor Jan Steyaert receives the Christian B. Anfinsen Award for pioneering nanobody technology, while Dr. Brian Kuhlman wins the Emil Thomas Kaiser Award for novel protein design and structural modeling.
The Weill Cancer Hub East will unite world-class experts in cancer biology, immunology, nutrition and metabolism to drive pioneering research. The hub aims to improve the effectiveness of immunotherapy, a promising approach for many types of cancers.
Researchers have identified a copper-free superconducting oxide that exhibits high-temperature superconductivity above 30K, expanding the understanding of unconventional superconductivity. The new material has significant implications for modern electronics and energy-efficient technologies.
Researchers at MD Anderson Cancer Center made several key discoveries, including the spatial organization of cancer-associated fibroblasts across various cancers and a study on treatment resistance in SMARCA4-mutant lung cancer. These findings highlight the importance of investigating cell populations in their spatial context to better...
Yali Dou, a molecular biologist at Keck School of Medicine of USC, has been elected as an AAAS fellow for her groundbreaking work in understanding leukemia and cancer. Her research on mixed-lineage leukemia proteins has led to the development of potential cancer treatments and a deeper understanding of epigenetics.
The American Heart Association and University of North Carolina Chapel Hill are building virtual care resources together. They share common priorities in advancing telehealth programs through evidence-based research and education.
University of Missouri researchers have been recognized by the American Association for the Advancement of Science (AAAS) for their distinguished contributions to multiple fields. Four Mizzou faculty members - Donald Burke-Agüero, Felix Fritschi, Scott H. Holan, and Richard Sherwood - were named AAAS fellows in 2024.
Researchers discovered TBX2 drives therapy resistance by shifting signaling from the androgen receptor to the glucocorticoid receptor. The study identified a strategy to target this switch, potentially predicting patient risk and offering new treatment approaches.
Researchers at Waseda University developed a new technique using terahertz imaging to visualize the internal structure of the mouse cochlea with high resolution. The study successfully demonstrated the potential of THz imaging as a non-invasive diagnostic tool for auditory disorders and other medical applications.
New research reveals that Duchenne muscular dystrophy profoundly affects the brain, leading to cognitive and behavioral challenges. The study found that some changes could be reversible, opening the door for targeted therapies.
A new method has been developed for engineering specific mtDNA deletions in human cells, providing a powerful tool to model disease-associated mtDNA deletions. This approach uncovers mechanisms of histiocytosis-associated neurodegeneration and investigates how mutant stem cells co-opt regeneration to make tumors grow.
A team of engineers at the University of Texas at Dallas has developed a new surface design that collects and removes condensates rapidly, challenging conventional theory. The discovery reveals a limitation in existing heat transfer models and inspires a new theory to explain the phenomenon.
A study using NHANES data found that inflammation, rather than diet and exercise, has the strongest association with telomere shortening. Managing chronic inflammation may be key to preserving telomere length and promoting healthy aging.
Researchers developed a sensor platform that tracks multiple metabolites continuously, offering a window into disease onset and health status. The technology harnesses natural biochemical processes, enabling reliable detection of over 800 metabolites, with potential applications in diagnosing metabolic disorders and optimizing fitness.
A team of scientists has created a new method to selectively modify specific proteins in complex biological environments. They achieved this using aptamers and deoxyoxanosine, allowing precise conjugation of desired sites on target proteins. This breakthrough technology has the potential to revolutionize cancer diagnosis and treatment.
Researchers have identified a novel mechanism of intercellular communication involving mRNA transfer between different types of stem cells. This phenomenon enables cell fate conversion and reverts human pluripotent stem cells to an earlier embryonic stage.
Researchers at UT Health San Antonio have discovered a way to delay or even block recurrence of the deadliest brain cancer after radiation by targeting senescent cells with experimental 'senolytic' drugs. This approach shows promise in preventing tumor growth and improving patient survival.
The ISS National Lab's new podcast, 'Between a Rocket & a Hard Space', offers exclusive insights from scientists, engineers, and visionaries on the future of space research. The first episode explores the groundbreaking science happening on the International Space Station, including its impact on medicine, technology, and industry.
Researchers at the University of Houston College of Pharmacy have identified a potential therapeutic target to repair injured muscles. They discovered that fibroblast growth factor–inducible 14 (Fn14) plays a crucial role in regulating satellite cell stability and function, which are responsible for muscle growth, repair, and regenerat...