News on early, curiosity-driven science that opens new directions. Covers materials discovery, AI-guided research, pediatric research standards, and energy science.
Alice Rossi, Angeliki Spathopoulou, and Gareth D. Chapman received the ISSCR Outstanding Poster Award for their innovative work on quiescent neural stem cells, neural stem/progenitor cell populations, and epigenetic dysregulation in Tatton-Brown-Rahman-Syndrome.
The International Society for Autism Research (INSAR) will hold its 24th Annual Meeting in Seattle, featuring 1600 posters, 28 oral sessions, and keynotes on topics such as daily challenges faced by the autism community and implementation science aimed at enhancing systems of care.
The collaboration aims to advance research on brain health with a focus on Alzheimer's disease. Initial projects will use CAS Content Collection and advanced technologies, including AI models and quantum computing to build and train disease-specific models.
A new web platform, AutoSolvateWeb, developed at Emory University enables chemists of all levels to configure and execute complex quantum mechanical simulations through chatting. The free platform uses cloud infrastructure and automates software processes on the backend.
The Greater Mouse-Tailed Bat uses its long tail as a dynamic sensing tool to avoid obstacles and orient itself in complex environments, especially when vision and echolocation are limited. The study found that the bats' ability to navigate decreased significantly when their tail was numbed.
Researchers at Nagoya University have discovered a unique sound stimulation technology that alleviates motion sickness, reducing symptoms by up to a minute of stimulation. The device stimulates the inner ear with a specific wavelength of sound, activating the vestibular system and improving balance.
Researchers have discovered that planarians can regenerate body parts and even grow new heads, reversing signs of aging such as lost neurons and muscle mass. This finding has implications for understanding age-related decline in mammals, including humans.
The Precision Omics Initiative Sweden (PROMISE) aims to integrate research with healthcare to boost both fields. The initiative leverages Sweden's strengths in genomic analysis, public healthcare system, and technology platforms to create new clinically relevant research results that can be reported back to benefit patients.
Researchers have gained detailed insights into RBP3's structure and mechanism of action, shedding light on its role in protecting the retina from diseases. The study suggests potential therapies to slow or stop retinal degeneration, including RP and myopia.
A study from Michigan Medicine researchers reveals that X-carrying and Y-carrying sperm compete for binding to Spindlins, influencing gene expression and the sex ratio. The findings suggest that this competition is crucial for maintaining the optimal balance of female and male offspring in mice.
Researchers developed a novel approach to understanding how transcription factors determine genetic programs in cells. They used CRISPR to knock out individual transcription factor functions across many blood cells at once and identified key genes and regions responsible for blood cell development.
A University of Maryland study reveals that young plants face a hidden trade-off between fighting disease and growing, leading to reduced reproductive fitness. Plants with stronger disease resistance as seedlings produce fewer flowers and seeds over their lifetime.
The Ralph L. Sacco Scholarships in Brain Health support research into vascular disease's impact on cognitive decline, dementia, and brain health. Researchers Hortense Triniac and Katy Walsh will study protein interactions to reduce stroke risk and investigate cerebral amyloid angiopathy.
Researchers created a bacterial evolutionary map that tracks plasmid gene exchange and identifies barriers to treatment. The study reveals new insights into the co-evolution of plasmids and E. coli strains, paving the way for targeted therapies against antibiotic-resistant infections.
Researchers discovered a mechanism that harnesses immune cells to produce opioids, potentially alleviating chronic pain. Estrogen and progesterone drive this process, which could lead to more effective treatments for women experiencing pain after menopause.
The Playbook Workflow Builder simplifies data analysis and streamlines collaboration for biomedical researchers. Researchers can design custom workflows using pre-built analytical components, removing a major barrier to data-driven discovery.
Researchers have successfully reprogrammed part of the large intestine to function like the nutrient-absorbing small intestine, reversing malnutrition in a preclinical study. The technique, which deletes the colon gene SATB2, restored nutrient absorption and improved survival rates in mice with short bowel syndrome.
The study found that solar wind radiation plays a dominant role in space weathering on the lunar farside, differing from the nearside. The Chang'e-6 samples showed less melt drops and no nanophase metallic iron particles, indicating variations in the space environment.
The National Comprehensive Cancer Network (NCCN) has awarded four early-career oncologists with $150,000 in funding to tackle pressing challenges in cancer care. The recipients will support studies aiming to improve cancer outcomes through molecular residual disease-guided adjuvant therapy and electronic symptom monitoring.
A novel circular RNA, circTP63-N, generated by back-splicing exons 2–4 of the TP63 gene is significantly downregulated in nasopharyngeal carcinoma (NPC) tissues. Restoring its expression effectively inhibits NPC cell proliferation and metastasis via engagement with HSP90AB1 to modulate the YAP1/Hippo signaling pathway.
The Ontario Institute for Cancer Research has announced support for five research teams developing new cancer drugs with improved efficacy and reduced side effects. The funded projects will focus on harnessing new insights about cancer biology to stop cancer from spreading and overcome treatment resistance.
Dr. Leanne Redman, a leading authority on body weight regulation, has received the prestigious E.V. McCollum Award for her translational research on maternal nutrition and energy regulation, with significant impact on public health. The award recognizes her dedication to advancing research that improves women's and families' health.
A research team has identified a previously unknown defense mechanism in Pseudomonas syringae, enabling the bacterium to produce chemical compounds that attract amoebae, which are then killed by toxic substances produced by the bacteria. This 'chemical radar' system also helps the bacteria infect plants in the presence of predators.
The Human Frontier Science Program has awarded 2025 Research Grants and Accelerator Awards to 104 of the world's most innovative scientists, spanning 30 nations. The grants support research on epigenetics, tick-borne diseases, and other life science topics.
A new study by McGill University researchers sheds light on the disruption of calcium transport in the brain's AMPA receptors, linking it to autism and intellectual disability. The findings could pave the way for treatments targeting these receptors, offering hope for patients with related neurological disorders.
Researchers at UTA uncovered how the flowerpot snake repairs its DNA and prevents harmful mutations, shedding light on genetic repair mechanisms that could deepen our understanding of human gene evolution. The study also reveals surprising findings about reproductive strategies and immune-related genes in reptiles.
Researchers have discovered a protective cloaking mechanism in jumbo phages that shield their genetic material from the host's immune system. This innovation could lead to new therapies for antibiotic-resistant infections.
Researchers have developed a new approach to personalize treatments for young cancer patients by growing tumors in chicken eggs and analyzing proteins. The technique, which combines genomics and proteomics, was successful in identifying a treatment option for a patient with a rare pediatric cancer.
A team of chemists from Virginia Tech found a way to visualize the intricate structure and chemical reactions of battery interfaces using an X-ray beam line. This breakthrough enables researchers to gain better control over these critical surfaces, potentially leading to cheaper, higher performance batteries.
Researchers discovered senolytics can target Alzheimer's disease-associated brain enzymes AChE and BChE without affecting healthy ones. This selective approach may lead to safer treatments that improve memory and reduce inflammation in older adults.
A novel AI-based method called scNET combines gene expression data with networks of possible gene interactions to identify biological patterns in response to drug treatments. The system reveals complex mechanisms underlying cellular behavior, providing insights for new therapeutic approaches.
The UK public considers the mobile phone the second most important invention of all time, with 52% viewing it as indispensable. Meanwhile, the wheel tops the list at 31%, ahead of electricity and penicillin.
Researchers Schmidt and Selvin will explore the connections between cardiovascular disease and diabetes, with a focus on large white blood cells and wearable continuous glucose monitors. Their work aims to develop new treatment therapies and improve health outcomes for people with diabetes.
A preclinical study found that linoleic acid, an omega-6 fatty acid, activates a major growth pathway in tumor cells, particularly in triple-negative breast cancer subtypes. A high-linoleic-acid diet enhanced tumor growth in mice with triple-negative breast cancer.
Recent technological advancements have expanded understanding of oceanic mesoscale eddies, regulating ocean energy distribution and material transport processes. The researchers identified four potential hotspots for future research, including eddy stability and air-sea interactions.
The University of Rochester's Wilmot Cancer Institute has been named the nation's 73rd designated cancer center by the National Cancer Institute. This prestigious designation recognizes the institute's excellence in cancer research, patient care, and community outreach.
A University of Minnesota Medical School study identified a key heart marker predicting ischemic stroke and dementia, which could lead to improved patient outcomes. The left atrium's ability to stretch was found to be the most accurate predictor.
Jennifer L. West, UVA Engineering Dean and Saunders Family Professor of Engineering, has been awarded the 2025 Pierre Galletti Award for her innovative research in biomaterials and nanomedicine. Her work has led to breakthroughs in treating cancer with precision, offering new hope to patients battling hard-to-treat cancers.
New research reveals mammals were shifting toward a more ground-based lifestyle several million years before the dinosaurs' mass extinction event. Analyzing small-fossilized bone fragments, scientists found signs of locomotory habit in end of limb bones from marsupial and placental mammals.
A USC Stem Cell mouse study has identified shared genes involved in regenerating cells in the ear and eye, which could lead to new treatments for hearing and vision loss. The researchers discovered that inhibiting a specific protein, p27Kip1, can encourage regeneration in both organs.
Researchers at UCalgary have discovered a protein called CD2AP that may hold the key to reducing Alzheimer's disease risk. Levels of this protein are lower in patients with AD, and its absence affects memory function, particularly in males. The study suggests a sex-dependent link between vascular system health and brain function.
All articles with at least one author based in Africa can now be submitted to the platform and will no longer require funding from a partnering research funder. This expansion aims to increase publication efficiency and improve the experience of African authors, while promoting the rapid sharing and discovery of high-quality research.
A study suggests that children were involved in creating prehistoric cave art due to their unique mental and cognitive traits, which allowed them to communicate with entities from the beyond. Children were believed to be liminal beings, bridging the gap between worlds, and delivering messages to non-human entities.
Cells dynamically adjust nuclear pore complexes like a retail store opening more checkout lines to regulate genome access. Research findings suggest that protein creation and disposal systems control the amount of NPCs in cells.
A recent study identified a quasi-conversion reaction on the cathode surface during discharging, leading to accelerated battery degradation. High nickel content exacerbates this effect.
Researchers developed new AI models, InstaNovo and InstaNovo+, to vastly improve accuracy and discovery in protein science. These models excel in tasks such as de novo peptide sequencing, identifying microorganisms, and discovering novel peptides, with implications for personalized medicine, cancer immunology, and beyond.
A team of scientists discovered a method to produce a stable and conductive bioelectric material without the need for a chemical crosslinker. The new process uses high heat to stabilize the material, producing devices with three times higher electrical conductivity and more consistent stability.
In extremely thin films of niobium diselenide (NbSe₂), superconductivity becomes confined to the surface when thinner than six atomic layers. This discovery challenges previous theories and could have important implications for understanding superconductivity and developing advanced quantum technologies.
Researchers have discovered that common anticancer drugs can reduce vascular growth in patients with PTEN Hamartoma Tumour Syndrome, offering new hope for treatment. These findings were made possible by the development of a mouse model and clinical trials using rapamycin and capivasertib inhibitors.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
A complete Quina technological system, used for making tools, was discovered in southwest China dating back 50,000 to 60,000 years. This finding disputes the widely held belief that development in China was sluggish during most of the Paleolithic period.
The ALL ALS Consortium has recruited over 300 participants across two studies, ASSESS and PREVENT, aiming to disrupt traditional ALS research by making data and samples available worldwide. The consortium seeks to discover new drug targets and approaches for effective treatments.
William Murphy, a genomicist at Texas A&M University, was named the 2025 SEC Professor of the Year. He studies genome structure, function and evolution to understand genetic basis of species traits and diseases.
The University of Malaga will coordinate an international consortium, 'X-SeeO2', aiming to hasten the use of cements as carbon dioxide sinks. The €4 million project aims to reduce CO2 emissions and promote the circular economy by upcycling waste.
The Endocrine Society expresses concern over the administration's plan to reorganize HHS, slashing federal funding and staff, which will hinder medical discoveries and approve new treatments. The society warns that politicization of scientific grants will harm millions of people needing medical care for endocrine conditions.
Researchers at Karolinska Institutet have developed a new method to diagnose COPD by analyzing protein levels in nasal lavage. The study found that elevated IL-26 levels can indicate an early phase of the disease, and may lead to new treatment strategies targeting this cytokine.
The American College of Cardiology is recognizing five primary authors with the William W. Parmley Young Author Achievement Award for their exceptional research papers published in JACC. The award highlights remarkable first-author publications by trainees in JACC and aims to elevate trainee-led research in the journal.
Dr. Rita Okoroafor's research integrates geochemistry, geomechanics, and reservoir engineering to improve understanding of fluid-rock interactions in subsurface technologies. Her work enhances hydrogen storage efficiency, optimizes geothermal reservoir performance, and improves CO2 storage security.
Four UT faculty members, Albrecht von Arnim, Alison Buchan, Susan Kalisz, and David White, were honored as AAAS Lifetime Fellows for their pioneering research in protein synthesis, marine microbes, and biogeochemical cycles. Their work has significant implications for agriculture, nutrition, and the environment.
A team of researchers has developed a groundbreaking high-temperature copper alloy with exceptional thermal stability and mechanical strength. The novel bulk Cu-3Ta-0.5Li nanocrystalline alloy exhibits remarkable resistance to coarsening and creep deformation, even at temperatures near its melting point.