A recent preclinical study from Weill Cornell Medicine researchers suggests that three-dimensional gene hubs may promote brain cancer. The findings, published in Molecular Cell, offer a new way to think about cancer beyond gene mutations and highlight the importance of understanding DNA organization in tumor cells.
Researchers analyzed massive audio recordings to create a dictionary of short melodies in English-language prosody, assigning functions and meanings. They discovered hundreds of basic patterns with linguistic functions, including conveying attitudes such as curiosity or surprise, and identified syntactic rules governing their order.
University of Oklahoma researchers create bioactive sugars to develop novel antibiotics against multi-drug-resistant infections in cancer patients. By using abundant, inexpensive, iron or metal-free, non-toxic blue light, the team can more easily and rapidly synthesize these important carbohydrates.
The American Heart Association funds research teams to investigate how risk factors for cardiovascular and kidney diseases impact women differently. The project aims to understand the biological significance of certain life cycles and societal factors on disease development.
A mysterious parasite is devastating fish farms globally, causing £50 million in losses annually. Researchers have discovered a new gene regulation process that could lead to the development of gene-based vaccines.
At NUTRITION 2025, experts will share the latest research on how genetics impact nutrition, the importance of early childhood feeding, and innovative strategies for managing obesity and promoting healthy aging. Researchers will also explore the role of diet in cancer prevention and control.
A study published in the Journal of Medical Entomology found a gene mutation in bed bugs that may contribute to their resistance to insecticides. The researchers, led by Warren Booth, discovered the mutation in 134 unique populations of bed bugs collected from North America between 2008-22.
Researchers at UT Arlington's CIHI are developing innovative solutions to address complex health needs in children with disabilities, behavioral health issues, and medical conditions. The projects aim to improve healthcare services, enhance quality of life, and promote healthier aging through cutting-edge research and model organisms.
Researchers at Tulane University identified a potential new way to treat idiopathic pulmonary fibrosis (IPF) using an FDA-approved cancer drug. The treatment works by blocking the CTLA4 protein, which blocks overactive T cells, allowing the immune system to clear out damaged cells that cause lung scarring.
A recent study found that people with plaque in their neck arteries have higher amounts of tiny plastic particles compared to those with healthy arteries. The concentration of these plastics was significantly higher in individuals who had experienced a stroke, mini-stroke, or temporary vision loss due to clogged blood vessels.
Bacteria use tactile sensors to detect surfaces and trigger biochemical signals for colonization. Understanding mechanosensing is crucial for improving gut health and preventing biofouling in industries.
The Colorectal Cancer Alliance is strengthening its commitment to Project Cure CRC, a nonprofit dedicated to ending the disease through innovative research and patient navigation. The organization has awarded three new grants and will present two poster sessions at the AACR Annual Meeting.
A team of researchers has identified a novel oncometabolite that accumulates in tumors and impairs immune cells' ability to fight cancer. The study highlights how the metabolic environment of tumors influences T cell function, opening new possibilities for improving cancer immunotherapy by targeting tumor metabolism.
Researchers from Penn Medicine will present data on latest advances in cancer science and medicine at AACR Annual Meeting 2025. Several experts, including Shelley Berger, will deliver presentations and Minisymposia talks.
Researchers developed a new method that uses simple grayscale eye photos to predict anemia in children. The technique analyzes patterns and textures in the conjunctiva of the eye, avoiding problems caused by different light conditions or camera models.
A UT Health San Antonio-led discovery could redefine drug discovery by turning IV medications into orally administered treatments for brain cancer, Alzheimer’s disease, and other complex conditions. The new strategy uses a protein receptor called CD36 to efficiently deliver large molecules into cells.
Researchers at Columbia University have discovered over a dozen new quantum states in twisted molybdenum ditelluride, which can be created without an external magnet. These states hold promise for building topological quantum computers with unique properties that could reduce errors and improve performance.
Researchers developed a quantum cooling engine that manipulates energy flow without feedback control, relying solely on quantum measurements. The engine successfully reversed heat flow, with entanglement found to influence the energy exchange between the working substance and measurement apparatus.
Researchers at CNRS have discovered that chemical intermediates of the citric acid cycle can form spontaneously in interstellar ice. This finding suggests that the raw materials necessary for life could be present in space and potentially delivered to Earth.
SourceCNRS·JournalProceedings of the National Academy of Sciences·DateApr 21, 2025
Chemists have confirmed a 67-year-old theory about vitamin B1 by stabilizing a reactive molecule in water. The discovery opens doors to more efficient ways of making pharmaceuticals using cleaner solvents.
A new study found that prenatal stress alters the expression of tiny RNA molecules in newborn blood, particularly in female children, affecting key enzymes in the brain's stress-regulation system. This may explain why some children are more vulnerable to developmental or psychiatric challenges.
A new study by Texas A&M University researchers has revealed insights into Mars' geological history and potential for ancient life. The team analyzed diverse volcanic rocks in the Jezero Crater, providing a window into the planet's distant past and signs of altered olivine.
John N. Weinstein, MD, PhD, chair of Bioinformatics and Computational Biology at MD Anderson Cancer Center, has been elected Fellow of the American Association for Cancer Research (AACR) Academy. He made significant contributions to advancing our knowledge of molecular profiles of cancer through multi-omic studies and data analysis.
Robert B. Hallock, a renowned physicist at UMass Amherst, has been awarded the Fritz London Memorial Prize for his pioneering work on superfluid and solid helium. He was recognized for his innovative achievements in liquid helium films and his groundbreaking discovery of giant isochoric compressibility.
A study published by UC Davis Professor Hugh Safford found Jeffrey pines growing above 12,657 feet elevation, surpassing previous records. This discovery suggests that climate change is allowing trees to move higher up mountains at an alarming rate, with the birds carrying seeds being a key factor.
The Extant Life Volumetric Imaging System (ELVIS) will test a new holographic microscope on the International Space Station to analyze the adaptability and resilience of microorganisms. The system aims to reveal how life might persist on distant moons and planets, significantly enhancing our search for life outside Earth.
Engineers at Duke University have demonstrated a method to create stable optical knots using laser beams, which could be used to transmit encoded information or measure turbulence in pockets of air. The team found that by adding more squiggles to the knot's features, they could make it stable for longer and resist degradation.
A study by the University of Konstanz found that individual bees within a colony exhibit different stinging behaviors, with some defending and others remaining calm. Social factors play a role, but personality is a key factor in determining group dynamics.
Research reveals DHX36 plays a crucial role in normal chromatin architecture and rRNA homeostasis during oocyte growth. DHX36 deficiency impairs meiotic maturation, post-fertilization embryonic development, and disrupts ribosome assembly.
Researchers with City of Hope will present more than 74 sessions on emerging technologies in cancer research, advances in natural killer cells, new clinical trial results, and precision medicine. The presentations will explore the use of artificial intelligence and multiomics to improve cancer care.
Researchers at the University of California San Diego have made a groundbreaking discovery about how our brains learn new information. Using sophisticated imaging techniques, they found that individual neurons follow multiple rules during learning, rather than one set of uniform rules as previously thought. This new understanding has s...
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center are presenting new findings on combination therapies for liver and pancreatic cancers, including a new organoid model for personalized head and neck cancer treatment. Additionally, they are discussing the potential of liquid biopsies for cancer detection and monitoring.
Researchers at MIT have discovered that a genetic variant can lead to defects in transfer RNA molecules, causing embryonic face cells to fail to fuse properly. This study sheds light on the molecular mechanisms underlying cleft lip and cleft palate formation.
Researchers employed a deep-learning-based method to detect footprints of DNA-protein interactions, allowing them to pinpoint disease-causing variants in non-coding regions. This approach could inform novel treatments for common diseases.
Researchers at MD Anderson Cancer Center have discovered that adding copper-loaded agents to radiotherapy can overcome radioresistance in preclinical models of thoracic cancer. A novel blood-based biomarker, OSMR, has also been identified in patients with acute myeloid leukemia (AML), which shows prognostic potential and can help ident...
A study by University of Arizona researchers found that nearly half of the time American children spend with their grandparents involves interacting with or watching media on a screen. Grandparents may want to watch along with their grandchildren or just want to understand what the children are watching.
A study co-authored by an Iowa State University professor identified a single protein that triggers chemical signals called effectors in cyst nematodes, which hijack plant cells. Disrupting this protein could severely reduce nematode infections, making it a powerful method for reducing crop damage.
A new machine learning model accurately predicts the fitness of AAV capsids based on their amino acid sequence, enabling more efficient and cost-effective gene therapies. The model's robustness and generalizability have been demonstrated through tests on independent datasets, offering a promising tool for capsid engineering.
Hongyou Fan, a Sandia scientist, has been recognized as an Outstanding Researcher by the Federal Laboratory Consortium for Technology Transfer. He is being hailed for his work on Disinfectant 2.0, a product that kills viruses, bacteria, and fungi for long periods.
Researchers at King's College London and Harvard University develop a detector that can identify axions, leading potential candidates for dark matter. The Axion Quasiparticle (AQ) technology has the potential to discover dark matter in five years with further development.
Researchers analyzing data from NASA's Perseverance rover uncover mineral-forming events beneath the Martian surface, bringing scientists closer to answering if life existed on Mars. Two separate generations of calcium-sulphate minerals are found in different regions, hinting at multiple potential windows for life to have existed.
Researchers developed fluorescent polyionic nanoclays that can be customized for medical imaging, sensor technology, and environmental protection. These tiny clay-based materials exhibit high brightness and versatility, enabling precise tuning of optical properties.
Researchers from HKUMed identified early mutations and risk factors for stomach cancer, laying the foundation for improved prevention and early detection. The study also developed a biobank of 'intestinal metaplasia' organoid models to study early cancer development.
The University of Missouri is partnering with a consortium to design and license a new research reactor, NextGen MURR, which will produce critical medical isotopes for cancer treatment. The project aims to enhance Missouri's role as a leader in nuclear science and medical research.
Dr. Sabine Ehrt takes the helm of microbiology and immunology at Weill Cornell Medicine, aiming to build on the department's reputation in tuberculosis research and expand into other areas. She seeks to foster cross-disciplinary collaborations and boost junior faculty mentorship.
A new genomics tool, refget Sequence Collections, streamlines genomic research by standardizing reference sequences. This enables scientists to compare data more efficiently and accelerate medical breakthroughs.
Dr. Rhonda Winegar investigates the effectiveness of music therapy in supporting neurological care, including its ability to reduce anxiety and depression in Alzheimer's patients. Her research also highlights its potential to regulate heart rate and blood pressure, as well as improve motor function in individuals with Parkinson's disease.
Researchers have developed a new method to detect gunshot residue at crime scenes, offering exciting opportunities for crime scene investigations. The innovative light-emitting lead analysis method is faster, more sensitive, and easier to use than current alternatives.
The Mount Sinai Fuster Heart Hospital cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, a leading patient experience organization. The hospital ranks among the top 5% of healthcare providers in delivering patient experience over three years.
Researchers discovered that gut bacteria can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling. These microbially modified bile acids antagonize the androgen receptor, driving anti-tumor immunity in mice with bladder cancer.
Researchers have developed a novel oxide material that exhibits autonomous spin orientation control in response to magnetic fields, allowing for the detection of both field direction and strength. The 'semi-self-controlled' spinning enables advanced angle-resolved spintronic devices with strong potential for next-generation technologies.
Researchers at Max Planck Institute use AI to design novel interferometric gravitational wave detectors, discovering dozens of top-performing designs that surpass known human solutions. These findings have the potential to improve detectable signal range by over an order of magnitude.
The UMass Amherst team, led by Stéphane Willocq, made significant contributions to particle physics, including studies of rare processes and Higgs boson properties. Their work explores the deepest questions about our universe and prepares for the High-Luminosity LHC upgrade.
Researchers have discovered antiferromagnetism in a real quasicrystal for the first time, exhibiting long-range magnetic order and opening new avenues for spintronics and magnetic refrigeration. The discovery aligns with sustainable development goals, building energy-efficient electronics.
Using intravascular imaging (IVI) to guide stent implantation reduces death, stent thrombosis, and repeat procedures in severely calcified lesions. IVI outperforms conventional angiography in improving patient outcomes.
A new study finds that a millisecond magnetar could have triggered the flashes of GRB 230307A, an extremely bright GRB detected in March 2023. The observation suggests that the magnetar model is consistent with the features of the prompt emission and the long-lasting X-ray plateau.
Scientists developed a nutritionally complete feed to sustain honey bee colonies, containing all necessary nutrients. The new food source thrived in field trials, reducing colony mortality and increasing survival rates.
Dr. Gadhamshetty, a leading expert in environmental engineering, brings over 25 years of experience to the role. He aims to expand the journal's influence and promote transformative research that addresses critical environmental challenges.
A new study provides unprecedented light on the Transpolar Drift's transport system and factors controlling its dynamics. The findings indicate that warmer temperatures could increase the spread of human-made pollutants in the Arctic.
Researchers will examine the link between cellular senescence and Parkinson's disease onset and progression. The team aims to find new ways to slow disease progression and establish senescence as a novel target for treatment.