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How evolution can change science for the better

Researchers developed an agent-based model to analyze the priority rule in science, finding that excessive rewards for priority can lead to lower-quality research. However, reforms like scoop protection can help mitigate this issue. To further improve science, measures like preregistration and criticism of research plans can encourage ...

SourceArizona State University·JournalNature Human Behaviour·DateJan 28, 2021

No limit to cardiovascular benefits of exercise, study finds

A new study published in PLOS Medicine found a significant inverse association between physical activity and the occurrence of cardiovascular disease, with participants in highest quartiles showing substantial risk reduction. The study used data from 90,211 UK Biobank participants and found no threshold for this association.

SourcePLOS·JournalPLOS Medicine·DateJan 12, 2021

New statistical method exponentially increases ability to discover genetic insights

Researchers have developed a new statistical method called Sum-Share that exponentially increases the ability to discover genetic insights. The method uses summary-level data from multiple sites to generate significant insights, outperforming existing methods in detecting genetic variations associated with cardiovascular conditions.

SourceUniversity of Pennsylvania School of Medicine·JournalNature Communications·DateJan 8, 2021

A new approach to study autoimmune diseases

Researchers update current research focus from 'immune-centric-only' view to better understand autoimmune diseases like type 1 diabetes and multiple sclerosis. The study identifies common gene expression changes at target tissues, highlighting the importance of studying both immune system and target tissues.

SourceIndiana Biosciences Research Institute·JournalJournal of Mathematical Sciences Advances and Applications·DateJan 6, 2021

New data-driven global climate model provides projections for urban environments

A new data-driven global climate model projects significant urban heat stress and reduced relative humidity in cities by the end of this century. The study's findings emphasize the need for local urban climate projections to support city planners' adaptation strategies, such as green infrastructure interventions.

St Petersburg University scientists discover an ancient island arc in the Kyrgyz Tien Shan

Researchers from St Petersburg University have discovered a complex of rocks forming an ancient island arc in the Songkultau Mountains of Kyrgyzstan, dated to around 500 million years ago. The finding provides valuable insights into the geological history of Central Asia and has implications for understanding large ore deposits.

SourceSt. Petersburg State University·JournalGeoscience Frontiers·DateDec 31, 2020

January issue ofSLAS Discovery"Cryo-EM: The Resolution Revolution and Drug Discovery"

The January issue of SLAS Discovery features the cover article 'Cryo-EM: The Resolution Revolution and Drug Discovery', which explores how Cryo-EM is influencing drug discovery projects. The journal also includes 13 articles on original research topics, such as high-throughput screening methods and protein-ligand interactions.

Accurate and efficient 3D motion tracking using deep learning

Researchers at Tohoku University developed a new sensing method using deep learning and a structure-aware temporal bilateral filter. The system can track complex motions with higher accuracy, enabling applications such as tracking small animal movements, fluid flow, and virtual reality finger movements.

SourceTohoku University·JournalIEEE Transactions on Visualization and Computer Graphics·DateNov 27, 2020

National study reveals new insights into avoidable harm in primary care

A national study of general practices in England found that diagnostic error (60%), medication incidents (25%), and delayed referrals (11%) are the main causes of avoidable harm. Researchers identified patient factors such as old age and multiple health problems, highlighting challenges in protecting patients from harm.

New mechanism affecting nerve impulses discovered

Researchers at Linköping University have identified a new mechanism by which substances can open specific ion channels and regulate nerve impulses. The study reveals a large group of substances that influence the coupling between ion channel parts, opening potassium channels in a specific manner.

SourceLinköping University·JournalProceedings of the National Academy of Sciences·DateOct 12, 2020

Researchers exploit weaknesses of master game bots

A new algorithm has been developed by Penn State researchers to train adversarial bots that can exploit weaknesses in master game bots using deep reinforcement learning. The algorithm successfully defeated a world-class AI bot in StarCraft II, highlighting the security threat of using such agents.