Articles tagged with Discovery Research
Researchers at UVA are using machine learning algorithms on biopsy images to diagnose environmental enteric dysfunction, a disease that affects hundreds of thousands of children worldwide. The technology has the potential to provide insights that evade human eyes, validate pathologists' diagnoses and shorten treatment times.
The EU General Data Protection Regulation (GDPR) complicates data sharing in research, with participants' consent withdrawal rights and limited data retention posing challenges. Researchers advocate for GDPR-compliant repositories and adaptable funding policies to ensure safe data sharing.
Research from the University of Exeter found that spending at least 120 minutes in nature a week significantly boosts psychological wellbeing. The study's findings suggest two hours of natural exposure is crucial for promoting overall health and wellbeing.
A new cloud-computing platform called brainlife.io is being used to support and publish reproducible neuroscience research, potentially reducing delays in discovery. The platform is being used to advance research on multiple health care studies, including sports concussion and Alzheimer's disease.
Four multi-institutional research projects were awarded up to $50,000 in funding through iTHRIV's Pilot Translational and Clinical Studies Program. These projects aim to address potentially life-threatening disorders such as hereditary angioedema and improve diagnosis and treatment of vascular diseases.
A novel enzyme from a soil fungus breaks down β-1,2-glucan into sophorose, revealing its potential role in the symbiosis of bacteria and plants. The discovery sheds new light on the diversity of glycoside hydrolases and their applications.
Researchers at Sandia National Laboratories have discovered a new avenue for understanding and controlling combustion processes, which will ultimately lead to cleaner engines. By analyzing a massive dataset of flames and fuels, the team identified correlations among chemical intermediates that play a role in pollutant formation.
Researchers from Singapore University of Technology and Design have discovered a method to achieve self-assembly of low-density droplets in microfluidic flows using three-dimensional microchannels. The study shows that by introducing a gradual increase in height, droplets can accumulate and assemble into ordered structures.
Scientists have identified a biomarker that can diagnose celiac disease in individuals following a gluten-free diet with high sensitivity and specificity. The discovery uses the relative expression of the UBE2L3 gene isoforms in blood samples, enabling accurate diagnosis without the need for gluten consumption.
Researchers found a significant amount of overlap between their data and citizen sightings, with roughly 65% for red foxes and 56% for coyotes. The study highlights the potential of citizen science to inform urban canid management and monitor human-carnivore interactions.
The Enabling FAIR Data project calls on all scientific disciplines to adopt a set of principles ensuring data is findable, accessible, interoperable, and reusable. This shift in research culture could increase opportunities for new research outcomes, enabling scientists to spend more time on research.
Researchers from Johannes Gutenberg University Mainz have made a groundbreaking discovery in thin film magnet interactions, revealing a new antisymmetric element that enables the creation of three-dimensional spin structures. These structures could lead to faster and more robust magnetic storage units with larger data capacities.
A new survey found that around one in five doctors are aware of patient feedback about their care online, while the majority did not encourage patients to leave feedback. The study also revealed that GPs view online feedback as mostly negative, particularly on social media.
Researchers at Princeton University discovered a new mechanism linking the circadian clock and fat metabolism through the Nocturnin enzyme. The study found that Nocturnin regulates specific metabolites to produce energy and protect cells from damage, leading to improved metabolic health outcomes.
Researchers discovered a signalling protein, semaphorin3d (Sema3d), that protects parathyroid glands from excessive activity, providing insights for drug development. Sema3d's protective role could also be relevant to other tumour types.
Defects in MOFs have been found to tailor these versatile materials for specific applications, such as catalysis and gas separation. KAUST researchers have developed a method to image defects using transmission electron microscopy, revealing that specific defects can improve MOF performance.
A new data analysis platform, CellBench, is being used to compare the performance of thousands of single-cell analysis options, helping researchers identify the best method for their questions. This will enable more accurate conclusions from large biological datasets, potentially leading to new discoveries and effective therapies.
Researchers found that matching mitochondrial DNA to nuclear DNA could be important when selecting potential donors for mitochondrial donation treatment. They discovered that mitochondria are fine-tuned to the nucleus and may influence the likelihood of certain mutations being passed on.
A survey of Japanese researchers found that 95% had shared their data, but only 56% had created a data management plan (DMP). The main reasons for not creating a DMP were unfamiliarity with funders' requirements and lack of institutional support. Japanese researchers cited supporting research progression and transparency as motivations...
Researchers at the University of Freiburg have identified a mechanism that clears blocked proteins from the mitochondrial entry gate. This discovery, dubbed 'mitochondrial protein translocation-associated degradation', has implications for understanding neurodegenerative disorders.
Researchers identified a key acid-activated protein channel (PAC) that could provide a new target for therapies for stroke, heart attack, cancer, and inflammation. The discovery was made by Johns Hopkins Medicine researchers who found the PAC protein in human cell lines using a novel method.
Research finds that fearful customers are sensitive to the size and scope of a data breach, whereas angry customers are not. The study also suggests that in the stock market, fear makes consumers more sensitive to breach size.
Researchers studied embryonic development to understand how neurons regulate digestive movement. They discovered that intestinal nervous system coordinates muscular contractions and reflexes.
A new CDC study cautions that sports whistles used by referees, coaches, and others are a risk factor for hearing loss. The study measured the acoustic signature of 13 whistle brands, finding sound levels between 100-120 decibels, which can exceed safe daily exposure within just a few seconds.
A new study found that people who walk faster have a higher life expectancy than those who walk slower, regardless of their weight status. The research used data from the UK Biobank and found that underweight individuals with a slow walking pace had the lowest life expectancy.
Researchers analyzed human tracks from 14,000 years ago, discovering five individuals entered the cave barefoot, including young children who were active group members. The team found evidence of social or symbolic activities within inner chambers, suggesting humans engaged in fun activities during exploration.
A new monkey species, Alophia, has been discovered in Africa at 22 million years old, bridging the 6-million-year gap in primate evolution. The discovery sheds light on the evolution of Old World monkeys and their dietary changes over time.
Researchers at Aalto University have discovered a surprising phenomenon where heavy particles move towards the regions with more vibrations, or antinodes, dubbed "inverse Chladni patterns", allowing for predictable motion control and potential applications in pharmaceutical research and microsystem assembly.
Penn State researchers have discovered a way to control substrate defects to improve the quality of 2D materials, enabling wafer-scale growth. The new method uses hexagonal boron nitride as a surface to orient transition metal dichalcogenides in a preferred direction.
A new species of medicinal mushroom, Ganoderma tropicum, was recorded in Thailand for the first time. The study found optimal growth conditions for mycelia production at specific temperatures and pH levels.
Scientists at CU Anschutz Medical Campus identified a rare genetic mutation causing an immune dysregulation syndrome, characterized by recurrent infections and autoimmune complications. The discovery provides unique insights into cell biology and suggests the possibility of treating the disease with gene therapy.
A global Therapeutic Area Standard has been released to represent data in research studies pertaining to CDAD, driven by the need for a major medical and infection control problem. The standard aims to accelerate clinical research and improve public health outcomes.
A new model describes how bacteria spread when moving in two different ways, providing a unifying theory for microbial communities. The theory reveals that the dynamics of spread are limited by the constraints of water and nutrient availability.
Abnormal necroptosis function contributes to cancer cell survival and multiple sclerosis, Parkinson's disease. Controlling necroptosis may lead to new treatments for these diseases.
Researchers identified two new neurodevelopmental diseases caused by ACTL6B gene mutations, leading to epilepsy, seizures, and cognitive delays. The study used induced pluripotent stem cells and CRISPR gene editing technology to understand the role of ACTL6B in brain development.
Researchers at TU Graz have made breakthroughs in super-battery research, finding ways to minimise the negative effects of singlet oxygen on redox mediators. They discovered a suitable quencher, DABCOnium, which transforms singlet oxygen into harmless triplet oxygen.
Researchers from the University of Kent have found that a newly discovered Ebolavirus, known as Bombali, is unlikely to cause severe disease in humans. The study compared amino acid sequences of virus proteins and identified positions that determine whether a virus causes disease in humans.
A University at Buffalo researcher and his team tested the impact of response options on the reliability of psychological measures, finding that six options appears to be the magic number for optimal accuracy. They argue that too few or too many options can lead to inaccurate results due to human cognitive limitations.
A new project at the Carl R. Woese Institute for Genomic Biology aims to discover a thousand new ribosomally synthesized and post-translationally modified peptides (RiPPs) using synthetic biology and automation. The project uses an automated robotic system, called iBioFAB, to identify new RiPPs and create new molecules.
Researchers at Utah State University have discovered a new mode of water surface skipping termed 'water walking', which involves elastic spheres gaining significant speed to maintain a deformed shape. The team's findings provide new insights into water impact physics and lay the foundation for future design of water-walking drones.
Researchers have discovered a new way to measure brain function in milliseconds using MRE, allowing scientists to visualize responses in the brain as they unfold. This breakthrough could help diagnose and understand neurological diseases like Alzheimer's, dementia, and epilepsy.
The new standard will facilitate collaboration and cross-study analyses to ensure the highest return on research investments. By structuring data in a common format, researchers can focus on discoveries that will have invaluable impact on clinical research and global public health.
Biologists seek to determine why bodies eliminate DNA during hybridization, aiming to grasp the molecular mechanisms behind this process. By studying frogs, they hope to unlock the secrets of genome elimination and its crucial role in species survival.
Researchers identified a helicase gene, ReqQ, involved in gene conversion and crossover frequency, the first of its kind in plants. This breakthrough may help breeders break up linked regions, increasing desirable genes without sacrificing vital plant functions.
A team of researchers unveiled an image of the shadow cast by a black hole at the center of galaxy Messier 87, using the Event Horizon Telescope and supercomputers like Stampede1 and Stampede2. The image confirms that supermassive black holes exist and match the appearance expected from simulations.
Researchers discovered close kin relationships among Stone Age individuals buried in megalithic tombs, suggesting a patrilineal society. The study found paternal continuity and an overrepresentation of males in some tombs.
Researchers used knife crime data to forecast London's most likely areas for fatal stabbings. Areas with high assault rates showed a significant increase in homicide risk the following year.
A new study published in Neuroscience & Biobehavioral Reviews found that sugar has no beneficial effect on mood and can even worsen it. Researchers analyzed data from 31 studies involving over 1,300 adults and discovered that sugar consumption increases tiredness and lowers alertness within an hour after consumption.
A team of researchers at Cardiff University has discovered that a family of lipids contribute to the development of abdominal aortic aneurysm by driving clotting in blood vessels. The findings suggest new treatments for this potentially life-threatening condition by regulating blood clotting.
Research shows forests in temperate, boreal, and tropical regions lower air temperatures by an average of 4°C compared to surrounding areas. The study suggests that management strategies can improve forest microclimates and mitigate the effects of global warming on biodiversity.
Researchers discovered that allergic reactions trigger changes in brain behavior development in unborn males and females. This study, published in Scientific Reports, found that immune cells play a critical role in sexual differentiation and may contribute to natural variations in male and female sexual behavior.
Researchers at the University of New Hampshire have made a patent-pending discovery that certain enzymes in roundworms behave differently than in humans, with amino acids potentially playing a key role. The findings advance scientific efforts to develop new pesticides to manage parasitic nematodes and reduce crop damage.
The EU-STANDS4PM forum aims to develop standardized transnational frameworks for data integration and in silico modeling in personalized medicine. This will facilitate the use of life science data in clinical research and accelerate growth of the European data-driven economy.
A new simulation system, AADS, combines photos, videos, and real-world trajectory data to create a more realistic autonomous driving environment. This allows for safer testing of self-driving vehicles in the lab before hitting the roads.
Banglin Chen, a renowned UTSA chemist, has received the Humboldt Research Award for his innovative work on metal-organic frameworks (MOFs) that can reduce hydrocarbons in plastics. His research focuses on developing membranes and commercializing materials for large-scale gas separations.
Research found that popular health apps regularly share user data outside of the app, often with commercial entities and technology companies. The study highlights the need for greater regulation and transparency in data sharing practices among health apps.
A new study by University of East Anglia researchers reveals that steep cliffs on volcanoes can cause a reversal in the pattern of deformation, leading to inaccurate tilt measurements. This affects data collected by monitoring equipment, such as tiltmeters, which are often placed on caldera rims.
A study by WVU researchers found that suicide rates among Medicaid-insured youth, including girls and young women, are significantly higher than those with private insurance. The researchers also discovered a higher proportion of Medicaid recipients died by hanging compared to non-Medicaid peers.
Researchers at Ohio State University have found a new material that can serve dual roles in electronics, simplifying the use of electrons and holes. This discovery could lead to more efficient electronic devices, such as solar cells, light-emitting diodes, and transistors.
Researchers at UVA have discovered a new potential contributor to age-related hearing loss: the cuticular plate, a foundation for hair cells. Genetic predisposition can weaken this plate over time, leading to progressive hearing loss.