Articles tagged with Laboratories
A team of scientists has discovered that a single amino acid difference in histone H3.3 enables it to serve as a memory device for the cell, marking genes that need to remain active. This epigenetic modification acts as a flag, signaling to the cell that genes in the vicinity should be inactive.
A national survey of primary care physicians found they often experience uncertainty in ordering and interpreting clinical laboratory tests, with missing results and confusing report formats being major challenges. Physicians reported that improved electronic decision-support tools and access to lab personnel would help reduce this unc...
A study published in Psychopharmacology found that even moderate alcohol levels can affect driving abilities of older adults, potentially leading to reassessment of legal blood alcohol limits. Researchers tested two age groups, ages 25-35 and 55-70, and found that a single drink impaired older drivers' skills
A new study predicts a doubling of notifiable disease reporting volumes with the implementation of electronic lab reporting, placing pressure on public health departments. The increased volume is expected to strain local and state health departments' workloads.
A new meta-analysis by IOF-IFCC found moderate but significant associations between bone turnover markers s-CTX and s-PINP, and risk of future fractures. The study confirms the clinical performance of these markers for fracture risk prediction in untreated individuals.
Researchers have identified two new biomarkers for acute kidney injury (AKI) in urine, allowing for earlier detection and treatment. The markers, TIMP-2 and IGFBP7, were validated using clinical adjudication and tested in independent labs.
Coral reefs face declining health due to nutrient pollution. Scientists emphasize that too many nutrients can harm corals more than a lack of them. Understanding nutrient competition is crucial for developing effective management strategies.
Scientists have detected extremely low-volatility organic compounds for the first time, contributing to aerosol formation that affects climate and air quality. The discovery may explain discrepancies between observations and theories about volatile organic compound conversion into atmospheric aerosol.
A team of researchers found that some cells exhibit random monoallelic gene expression during development, which can affect protein production and potentially lead to diseases. The phenomenon is more common in mature cell types than stem cell precursors.
Researchers at Cold Spring Harbor Laboratory have proposed a new method for analyzing Big Data using mutual information, which can reveal patterns without prior assumptions. This approach challenges the latest statistical tools and has the potential to greatly benefit modern data analysis in biology and other fields.
Researchers at Cold Spring Harbor Laboratory have identified a novel neural circuit linking the amygdala with the brainstem's fear response center. This discovery sheds light on how fear is translated into behavioral responses, paving the way for potential treatments of anxiety disorders like PTSD.
A panel of 35 genetically characterized DNA samples is now publicly available to help standardize Rett syndrome testing and improve diagnostic accuracy. The collection contains a wide variety of MECP2 mutations associated with most cases of the disorder.
Dr. Ronald G. Crystal developed the first in vivo adenoviral gene delivery vector, accelerating gene therapy translation from lab to clinic. The Pioneer Award recognizes his seminal work on adenoviral vectors.
System 91S is a tropical low-pressure area located northeast of Maputo, Mozambique, with heavy rainfall rates occurring over the Mozambique Channel. Wind shear has increased, causing the system to elongate and reducing its chances for tropical development.
Briand's work on model-based software verification and testing has been recognized for its outstanding contribution to reliability engineering. The award honors his efforts to deliver predictable dependable software-intensive systems within cost and time constraints.
Researchers at the University of York have discovered how one group of gut bacteria, Bacteroidetes, digest complex sugars found in fruits and vegetables. This understanding sheds light on nutritional issues like prebiotics and probiotics.
Researchers at Cold Spring Harbor Laboratory have discovered two proteins that control the structure of chandelier cells, a type of inhibitory neuron important in epilepsy and schizophrenia. The study found that DOCK7 and ErbB4 regulate axonal projections, allowing one cell to block or modify hundreds of other cells.
Researchers from EPFL have created a new method to eliminate external noise in nanomechanical oscillators, allowing for nearly perfect ultra-efficient sensors. This breakthrough enables the detection of very small particles and masses with high accuracy, opening up new frontiers in fundamental science and applied studies.
Scientists have identified a genetic mechanism to increase crop yields by tweaking a 'hybrid vigor' gene in plants. By understanding how this gene affects flowering time and fruit production, researchers may be able to develop new strategies to improve agricultural productivity.
Researchers identified a SNP in Cyfip2 associated with cocaine response, highlighting the need for genetic quality control in mouse populations. The study used C57BL/6J and 6N mice substrains developed over nearly a century.
A recent study published in Diabetes Care journal found that artificially sweetened drinks produced a neutral response in healthy humans, unlike previous findings. The researchers aim to better understand the effects of long-term artificial sweetener intake on human health.
A team of researchers from University of California, Riverside claims that ancient zircons contain 'diamonds' which are actually fragments of polishing compound used in the laboratory analysis. The discovery was made using high-resolution electron microscopy and suggests no indigenous diamonds exist in these samples.
The Association for Molecular Pathology proposes a new term, Laboratory Developed Procedure (LDPs), to describe service-oriented tests. LDPs rely on laboratory professionals for design, consultation, and interpretive reporting in clinical care.
Researchers are using an advanced humanoid robot called Nao to measure human interaction with robots in public spaces. The project aims to enhance the public realm as a space where people can interact under conditions of privacy and equality.
The study found that stimulation at Neiguan with a frequency of 1 Hz and long duration of 180 seconds significantly increased cerebral blood flow and decreased the ratio of infarct volume. A frequency of 2/3 Hz and short duration of 5/60 seconds also showed positive effects.
A new laboratory rearing method has been developed to study the western bean cutworm's susceptibility to Bacillus thuringiensis toxins. This allows for the evaluation of toxin efficacy and potential resistance development.
Researchers at the University of Adelaide discovered that the stomach's nerves act as a circadian clock, controlling food intake. The discovery suggests that the gut signals the brain about when to stop eating, and how this timing varies throughout the day.
A study published in the Journal of General Internal Medicine found that providing real-time cost information to physicians reduces the ordering rate of laboratory tests, including both high- and low-cost tests. This intervention increased physicians' knowledge about costs and their willingness to order cost-effective services.
Researchers have found a way to reduce the contact time of water droplets on surfaces by at least 40%, potentially aiding in ice prevention and wing efficiency. The breakthrough could also have implications for ecology and industry, including reducing corrosion and improving turbine blade efficiency.
Researchers developed a stretchy polymer that coats the electrode, binds it together, and spontaneously heals tiny cracks during battery operation. This self-healing coating extends silicon electrodes' lifespan up to 10 times, making them suitable for electric vehicles and cell phones.
A recent study analyzing 1.6 million results from 46 commonly ordered lab tests found that 30% of tests are probably unnecessary, while equally as many necessary tests may be going unordered. The research suggests that ordering the right tests during initial evaluations can lead to fewer errors and better patient care.
Recent experiments have found that lithium bound to carbon walls in fusion devices plays a key role in improving plasma performance. The combination of lithium, oxygen, and carbon improves deuterium retention and reduces recycling, leading to enhanced energy confinement and reduced edge plasma instabilities.
Neurosurgeon residents at UCSF implemented a quality improvement program to reduce unnecessary diagnostic laboratory tests, resulting in a 47% decrease and cost savings of $1.7 million. Patient care was not compromised, and the program improved patient satisfaction and reduced hospital costs.
UC Davis is part of a five-year collaboration to develop real-time cyberattack detection and response systems without human intervention, leveraging industry partners and joint research programs. The $48.2 million alliance aims to enhance cybersecurity in Army networks and address complex challenges in cyberspace.
Cesar Arias has received the Oswald Avery Award for Early Achievement from the Infectious Diseases Society of America (IDSA) for his groundbreaking work on superbugs and antibiotic resistance. His research aims to combat the growing threat of antibiotic-resistant bacteria and has been recognized globally.
Scientists at Cold Spring Harbor Laboratory found that specific cells in the fruit fly brain respond to food odors, predicting how much flies like a given odor. By manipulating these neurons, researchers can influence fly behavior, shedding light on human obesity and food choice.
The five-year collaborative research alliance will focus on detecting adversaries and attacks, measuring and managing risk, and altering environments to achieve best results at the least cost. Researchers will develop predictive models to make real-time decisions that lead to mission success.
Physicists from Louisiana Tech University contribute to an international team that reports first results for the proton's weak charge based on precise new data from Jefferson Laboratory. The Q-weak experiment measured the weak interaction's unique property of parity violation, revealing a tiny asymmetry in electron scattering rates.
A multidisciplinary team treats a patient with severe OCD using DBS, achieving significant improvements in symptoms and quality of life. Whole-genome sequencing reveals gene variants associated with neuropsychiatric illness, providing insights for personalized care.
Scientists at SLAC National Accelerator Laboratory and Stanford University have demonstrated a 'laser on a chip' technology that accelerates electrons at a rate 10 times higher than conventional methods in a nanostructured glass chip. This breakthrough could lead to compact accelerators for science, medicine, and research applications.
Researchers cataloged interactions between breast cancer cells and normal cells in their environment, finding that most signals promoted cancer. Blocking multiple signals simultaneously inhibited tumor growth more effectively than blocking individual signals.
The National Science Foundation has awarded $50 million to Cold Spring Harbor Laboratory and other institutions to create a national cyberinfrastructure for the biological sciences. This grant will enable scientists worldwide to analyze large datasets efficiently, addressing global research priorities.
A new study reveals how maize plants regulate stem cell activity through a functional interaction between a G protein and an unexpected class of cell-surface receptors. The research, led by Professor David Jackson, provides insights into the CLAVATA signaling pathway and has implications for increasing crop yields.
Researchers created an animal model of adult-onset spinal muscular atrophy (SMA) using the TSUNAMI method, providing insight into disease progression and potential treatment. The study revealed that only moderate levels of SMN protein are needed in the adult nervous system for normal function.
Researchers at GSI Helmholtz Center and Mainz University successfully identify element 115 using a novel detector system. The experiment confirms the existence of the superheavy chemical element, providing a way to directly identify new elements beyond atomic number 104.
A pilot study by UC Davis researchers found that glucose monitoring systems with an autocorrect feature can produce more accurate blood glucose measurements, improving insulin dosing and glucose control for burn patients. This technology can help reduce mortality and morbidity in these patients.
Researchers have developed a fast and affordable blood test to detect early signs of organ rejection in transplant patients. The new test uses Droplet Digital PCR technology, which can identify graft-derived cell-free DNA released into the bloodstream by dying cells from the transplanted organ.
Researchers at Kansas State University and Avatekh Inc. are developing advanced nonlinear algorithms and circuits called adaptive nonlinear differential limiters (ANDLs) to reduce electronic noise and interference in industrial and consumer products. The technology may improve smartphone performance, battery life, and operating range.
The UNC-Malawi cancer pathology laboratory has provided invaluable service to patients and built capacity at a national teaching hospital. The lab, which assessed over 3,600 specimens, is now helping to relieve diagnostic delays and provide essential diagnostic services to Malawians suffering from cancer.
A NASA team outlines priorities for a future Europa lander mission to study its potential habitability. The mission would investigate the composition and chemistry of Europa's ocean and the thickness, uniformity, and dynamics of its icy shell.
A study has identified two networked groupings from 26 genes associated with autism that are overexpressed in the cerebellar cortex. The findings suggest specific brain regions implicated in pathology and complement genomic and neuroimaging analyses to obtain a broader picture of the autistic brain.
Researchers at University of California, Riverside identified odor molecules that impair mosquitoes' carbon dioxide detection machinery. Olfactor Labs developed a wearable patch that delivers non-toxic compounds to repel mosquitoes, providing up to 48 hours of protection.
Researchers link black-legged ticks to an increased risk of Powassan encephalitis, a rare but serious illness with a 10-15% fatality rate. The study found deer tick virus in over 13,500 ticks, with infected adult ticks concentrated east of the Hudson River.
A new guide from the Infectious Diseases Society of America and American Society for Microbiology provides guidance on using laboratory tests to diagnose infectious diseases. The guide highlights key findings, including the importance of accurate lab results and proper specimen collection and management.
Valery Fokin receives $3.75M grant to establish laboratory at MIPT, focusing on biomarker development for inflammation, cancer, and immune diseases. The lab will facilitate collaborations between Scripps and Russian scientists and companies.
Researchers reviewed existing studies on nanoparticle toxicity and found that ingestion is unlikely to cause health problems at typical exposure levels. However, the literature lacks evidence on long-term effects or subtle alterations in gut microbial populations.
Prader-Willi syndrome is associated with the loss of non-coding RNAs, resulting in dysregulation of circadian and metabolic genes. The study found that mice engineered with the loss of a long non-coding RNA showed altered energy use and metabolic differences during sleep.
Researchers at Virginia Tech have developed a new three-dimensional microfluidic device that can customize channel shapes to mimic natural conditions. The technology has potential applications in water and food safety, as well as biological terrorism detection.
Researchers at Washington University School of Medicine have identified a way to trigger the reproduction of human insulin-producing beta cells in a laboratory setting, potentially removing a significant obstacle to transplanting these cells as a treatment for patients with type 1 diabetes. This new technique uses a cell conditioning s...
A study by IDIBELL researchers recommends the use of faster and more potent antithrombotic drugs in high-risk heart attack patients. The study found that only 25% of patients responded to aspirin and 10% responded to clopidogrel, leading to a recommendation for stronger alternative treatments.