Articles tagged with Laboratories
A comprehensive study led by Mayo Clinic in 12 countries validates the accuracy of RNA genomic sequencing techniques and laboratories. The research establishes best practices for laboratories to ensure reproducible results, enabling clinicians to make informed decisions based on genomic data.
Researchers at Nova Southeastern University will investigate biological indicators in men with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The four-year study aims to develop more effective treatment plans using existing drugs.
Researchers at SLAC National Accelerator Laboratory have created a molecule that conducts electricity in one direction, paving the way for shrinking chip components down to the size of molecules. The hybrid molecule, known as buckydiamondoid, was made by combining carbon spheres (buckyballs) with tiny diamond cages (diamondoids).
Researchers at the University of Georgia have found that people with more yellow pigment in their eyes can see better in hazy conditions. The study suggests that eating leafy green vegetables can help maintain healthy vision.
A novel mutant mouse model, NRV2, has been developed to study retinal neovascularization, a condition characterized by abnormal blood vessel growth in the retina. The researchers found that NRV2 mice show spontaneous retinal depigmentation and neovascularization, which mimic the early clinical stages of RAP disease in humans.
Researchers confirm lithium-6 production in Big Bang energy range, contradicting observed lithium concentrations in stars. The study resolves the 'lithium problem,' a stubborn issue in astrophysics.
Researchers at Southern Methodist University found that elite sprinters use a unique gait feature to maximize speed, delivering a firm and rapid punch to the ground upon contact. The study, which compared data from competitive sprinters to other fast-running athletes, suggests that there is only one way to achieve high speeds.
A team of researchers found significant security vulnerabilities in full-body backscatter X-ray scanners used at US airports between 2009 and 2013. They demonstrated how attackers could conceal firearms and explosives using low-tech techniques, showcasing the need for rigorous testing and independent evaluation.
Researchers discovered a subset of microRNAs that regulate sex differences in fruit flies, with implications for understanding human developmental defects and disease. The study found that these small RNA molecules orchestrate complex genetic programs that shape the structures distinguishing males and females.
Researchers discovered graphene devices have different electronic properties at edges and centers. Edge conduction was found to be p-type, while the center exhibited n-type electron conduction. These findings offer insights into developing graphene nanoribbon devices and studying edge photocurrents.
Scientists have created a new mouse strain that restores the ability of wild-derived mice to exhibit normal aggression and maternal instinct towards pups. This breakthrough allows researchers to explore the biological roots of aggressive behavior in females, including their reaction to pheromone signals.
Researchers at MIT have developed a method to study bonding failures in materials, revealing the crucial role of moisture in setting the stage for failure. The findings could lead to the design of more durable composites and prediction of their strength under specific conditions.
The Jackson Laboratory will establish a new Neurobehavioral Biometry Center with a $1 million pledge from the Cornelia Cogswell Rossi Foundation. The Center aims to accelerate research in neurological and neurobehavioral disorders by assessing behavior related to disease characteristics and therapy responses.
The article introduces a proof-of-concept figure that generates data 'on the fly' when an online article is viewed. Readers can select parameters to alter the generated figure, allowing for self-evaluation of the data. This innovation aims to improve transparency and reproducibility in scientific publishing.
Researchers at Jackson Laboratory pinpoint a new mechanism behind neurodegeneration in mice, linked to a mutation in the tRNA gene n-Tr20. The study reveals that individual tRNA genes can be tissue-specifically expressed, leading to disease or modifying phenotypes.
A researcher from Moscow Institute of Physics and Technology has developed a reliable mathematical model of Titan's atmosphere, which matches the latest data surprisingly well. The model takes into account various chemical reactions between neutral molecules and ions in the upper layers of Titan's atmosphere.
Researchers at China's PandaX facility aim to detect direct evidence of dark matter interactions with xenon nuclei and observe double-beta decay. The new detector is designed to distinguish between nuclear recoils and electron recoils, with promising results from previous experiments like XENON100.
Researchers used an ultrafast optical laser and X-ray pulses to study the movement of electrons between atoms in exploding molecules. They observed that electrons can jump over surprisingly long distances, up to 10 times the length of the original molecule, shedding new light on microscopic dynamics.
A team of scientists at Cold Spring Harbor Laboratory has identified a gene called LIN-42 that controls the timing of events during development, governing a broad range of events throughout growth and behavior. The study provides insight into how species evolve without creating new genes.
Researchers analyzed clinical samples from suspected Lassa fever cases in Sierra Leone and found nearly 9% tested positive for Ebola virus. The study demonstrates that Ebola has been circulating in the region since at least 2006.
Researchers found that advances in parasite purification and culture methodologies significantly increased publication rates by 3-10 fold, leading to new molecular tools and resources. This study provides a side-by-side comparison of the publication records for four major genera of protozoan parasites affecting mollusks.
Researchers used physical analog models to simulate Ganymede's geologic structures, finding that stretching forces created characteristic patterns of ridges and troughs. The study suggests that a process involving crustal breaks due to large amounts of extension is the primary mechanism for forming these features.
A study by UC Riverside researchers reveals that certain cells in the intestinal and respiratory systems have an electrostatic repulsion field, protecting against bacterial and viral infections. This finding could lead to improved diagnosis and treatment of certain infections.
Physicists create quantum dots with identical, deterministic sizes using a scanning tunneling microscope. This achievement opens the door to quantum dot architectures free from uncontrolled variations.
Scientists have discovered that Lassa virus uses a two-step process to enter cells, involving the transport of the virus to a lysosome and the binding to an interior cell receptor called LAMP1. This finding could lead to new approaches for preventing the disease.
A study found that lab monitoring tests are not always ordered as recommended, with factors such as specialist status, age, and general health influencing the use of these tests. The research suggests that interventions to improve laboratory monitoring should focus on areas with the greatest potential for improvement.
The Pew Charitable Trusts has awarded research funding to 10 Latin American scientists through its Biomedical Sciences program. The fellowship provides flexible funding and networking opportunities to help early-career scientists develop skills and connections that will aid them in becoming scientific leaders in their home countries.
Researchers have made the first structural observations of liquid water at temperatures as low as minus 51 degrees Fahrenheit, revealing new insights into its molecular structure and behavior. This study opens a new window for exploring liquid water in extreme conditions, which is relevant to global ocean currents, climate, and biology.
Research at Granada finds that alcohol consumption markedly impairs night-vision and deteriorates the optical quality of images seen. The study concludes that ethanol from alcoholic drinks disturbs the tear-film, facilitating evaporation of the aqueous part, which in turn degrades image quality.
A new study by MIT researchers shows that commuting times are generally independent of distance traveled, as long as commuters have access to various transportation options. This is demonstrated through the use of mobile phone data across five locations on four continents.
A 14-year-old boy's rapid recovery from brain-inflaming encephalitis thanks to next-generation sequencing techniques. The innovative approach, developed at UCSF, enables quick diagnosis and treatment of infectious diseases, revolutionizing clinical laboratory practices.
The laboratory uses pneumatic launchers and high-speed cameras to study structural elements' response to impacts. Researchers aim to design armor plating that can withstand various types of collisions.
Researchers report that Hawaiian crickets have lost their songs due to a natural defense mechanism against parasitoid flies. The silent crickets avoid the deadly flies and still mate by positioning themselves near singing males, showcasing convergent evolution in action.
A study published in Clinical Infectious Diseases found that nearly seven million Americans seek medical attention for sore throats each year, with one in 10 cases being strep throat. The researchers concluded that performing a laboratory culture can help doctors and patients avoid both under-treatment and over-treatment of sore throats.
A recent study published in Experimental Economics found that intermediaries significantly increase corruption, regardless of their level of involvement. The researchers designed a laboratory experiment to test the impact of intermediaries on corrupt behavior, and their results confirm this suspicion.
A recent study by the University of Kent found that individuals who drink moderately in a group are less likely to view risky situations with greater caution. The research showed that social interaction in groups can reduce the tendency of individual drinkers to accept risks.
Researchers at Cold Spring Harbor Laboratory discovered a protein called Chd5 that plays a crucial role in chromatin remodeling during sperm development. The team found that Chd5 is essential for maintaining the genetic information of male fertility, and its absence can lead to infertility and increased risk of disease.
The robotic arm, developed by EPFL researchers, is capable of catching projectiles with irregular shapes and trajectories. It achieves this through a combination of machine learning algorithms and real-time adjustments, enabling it to catch objects in less than five-hundredths of a second.
Researchers at the Max F. Perutz Laboratories have developed a method for generating specific and inheritable mutations in the marine bristle worm Platynereis, enabling detailed in vivo functional analyses and advancing research in neurobiology, chronobiology, evolutionary developmental biology, and marine biology.
Researchers will simulate the impact of tsunamis on urban areas, modeling how water channels around clusters of buildings. The facility aims to produce engineering guidelines to mitigate future tsunami impacts. The research has far-reaching implications for building and urban design in tsunami-prone areas.
Researchers from Inserm and the Institut Pasteur have identified a new variant of the Ebola virus in Guinea. The virus is highly contagious and has a high mortality rate, with symptoms including fever, severe diarrhea, and vomiting. The discovery highlights the need for increased measures to prevent transmission from wild fauna to humans.
The Association for Molecular Pathology (AMP) released a report recommending a molecular diagnostics curriculum for medical laboratory scientists, balancing accreditation, certification, and job market needs. The recommendations aim to prepare future scientists for high-complexity testing and support the growth of genomic technology.
The human immune system uses enzymes like ADAR1 to modify viral genetic information, rendering it useless for new virus particles. The study reveals how the cell protects itself from accidental import of viral RNA into the nucleus.
A new study found that people perceive foods with rough textures to have lower calorie content. In laboratory experiments, participants consumed more soft than hard brownie bits when not focused on calorie content and vice versa when focused on it.
Researchers at Aalto University have developed a method to observe immediate changes in brain function during movie viewing. The study found similar brain signals in individuals watching the same movie, suggesting that the contents of the film affected certain brain functions in a similar manner.
A research team developed a force sensing skin that can identify potential bruising locations on a child surrogate to differentiate between accidental trauma and child abuse. The system provides a roadmap documenting a child's exposure to impact, critical for forensic analysis.
Jun Shen, Ph.D., was honored as the 2014 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer Inc. Travel Award for her platform presentation on a novel combinatorial algorithm predicting pathogenicity of human missense variants. The award recognizes Dr. Shen's scientific merit and supports her work in medical genetics ...
A study found that Institutional Animal Care and Use Committees (IACUCs) at leading US institutions are dominated by animal researchers, with only 10% of members being non-scientist public representatives. This bias may contribute to deficiencies in the IACUC oversight system and marginalize input from public members.
A new mathematical model predicts where different types of neurons are located in the brain based on their molecular identity. This approach enables scientists to draw an increasingly accurate map of neuronal distribution in the brain.
The Journal of Vascular and Interventional Radiology honored researchers Eliseo Vano and Marwan Moussa for their contributions to radiation safety and chemotherapy delivery. The SIR Foundation awards recognize excellence in published clinical and laboratory investigations, advancing scientific knowledge and improving patient care.
James F. Benenati, a leading interventional radiologist and medical director at Baptist Cardiac & Vascular Institute, will deliver the opening plenary at SIR's Annual Scientific Meeting in San Diego. He has made significant contributions to the field through his research and training programs.
A team of scientists has discovered that a single amino acid difference in histone H3.3 enables it to serve as a memory device for the cell, marking genes that need to remain active. This epigenetic modification acts as a flag, signaling to the cell that genes in the vicinity should be inactive.
A national survey of primary care physicians found they often experience uncertainty in ordering and interpreting clinical laboratory tests, with missing results and confusing report formats being major challenges. Physicians reported that improved electronic decision-support tools and access to lab personnel would help reduce this unc...
A study published in Psychopharmacology found that even moderate alcohol levels can affect driving abilities of older adults, potentially leading to reassessment of legal blood alcohol limits. Researchers tested two age groups, ages 25-35 and 55-70, and found that a single drink impaired older drivers' skills
A new study predicts a doubling of notifiable disease reporting volumes with the implementation of electronic lab reporting, placing pressure on public health departments. The increased volume is expected to strain local and state health departments' workloads.
A new meta-analysis by IOF-IFCC found moderate but significant associations between bone turnover markers s-CTX and s-PINP, and risk of future fractures. The study confirms the clinical performance of these markers for fracture risk prediction in untreated individuals.
Researchers have identified two new biomarkers for acute kidney injury (AKI) in urine, allowing for earlier detection and treatment. The markers, TIMP-2 and IGFBP7, were validated using clinical adjudication and tested in independent labs.
Coral reefs face declining health due to nutrient pollution. Scientists emphasize that too many nutrients can harm corals more than a lack of them. Understanding nutrient competition is crucial for developing effective management strategies.
Scientists have detected extremely low-volatility organic compounds for the first time, contributing to aerosol formation that affects climate and air quality. The discovery may explain discrepancies between observations and theories about volatile organic compound conversion into atmospheric aerosol.
A team of researchers found that some cells exhibit random monoallelic gene expression during development, which can affect protein production and potentially lead to diseases. The phenomenon is more common in mature cell types than stem cell precursors.