Articles tagged with Laboratories
A single monoclonal antibody isolated from a human Ebola survivor has been shown to completely protect monkeys from lethal infection with the virus. The antibody, known as mAb114, was effective even when given five days after exposure, suggesting it could be used as a potential treatment for human cases.
Researchers developed an algorithm called Melvin to design novel quantum experiments, finding unfamiliar solutions without relying on human intuition. The algorithm has led to dozens of new experimental tricks and is being built in laboratories.
The 'NewSTEPs 360' program aims to improve timeliness measures in newborn screening, resulting in more infants receiving early treatment for rare but serious conditions. The initiative provides quality improvement training and technical assistance to selected states, aiming to reduce delays in diagnosis and save lives.
Concentrations of iron similar to those delivered through standard treatments can trigger DNA damage within 10 minutes, when given to cells in the laboratory. Researchers from Imperial College London suggest that standard treatment dosages may be causing cell damage, highlighting the need for careful consideration of iron levels.
Researchers at Iowa State University have successfully developed a hybrid technology that combines genetic engineering and electrocatalysis to convert sugar into biobased, unsaturated nylon-6,6. This process offers several advantages, including low operating temperatures, the use of cheap metals, and production from water.
Researchers have discovered a new bacterial species, B. mayonii, that causes Lyme disease in people in the upper Midwestern US. The species was previously unknown and has been identified through PCR testing of patient samples.
A new study published in Nature Biotechnology reports that a 2D-NMR spectroscopy method can reliably assess the atomic structures of biologically similar products, yielding equivalent fingerprints. The method's precision is demonstrated through an interlaboratory comparison of four versions of a therapeutic protein drug.
A new study published in the International Journal of Obesity found that close to half of Americans who are considered
Researchers found that unexpected sports wins and sunny days increased daily lottery purchases in New York City neighborhoods. The effect was seen across both wealthy and poorer areas, with a total increase of $160,000 in spending on lottery gambling on days with multiple sports team wins.
Researchers at ETH Zurich are studying the Atlantic hagfish's remarkable slime to understand its structure, properties, and formation process. The slime, composed of protein threads and mucin, can immobilize vast amounts of water, making it a potential inspiration for creating novel super hydrogels with numerous applications.
Researchers developed a tensile tester using LEGO blocks, showcasing their potential for prototyping stretchable and flexible electronics. The innovative approach combines cost-effective machinery design with easy handling, comparable to commercial testing devices.
A study by the Canadian Medical Association Journal found that five percent of Ontarians account for 65% of provincial health care costs, with the top 1% accounting for one-third of these costs. The study tracked $30.5 billion in healthcare spending, which is about 75% of total government health expenditures.
Researchers at Stanford University School of Medicine found that trimming the nails of laboratory mice can cure a common and life-threatening skin disease. The technique saved 93% of mice from ulcerative dermatitis, a condition that caused deep ulcers and led to animal euthanasia.
Agricultural researchers propose a network of research stations across Europe to increase collaboration and accessibility. The ECOFE project aims to create a shared resource for open-field experiments, addressing challenges such as productivity increase, climate change, and environmental sustainability.
Dr. Christoph Aeppli and colleagues studied how petroleum released during the 2010 Deepwater Horizon oil spill transformed in the environment over six years, finding novel compounds with potential toxic effects on marine organisms.
Researchers at Princeton Plasma Physics Laboratory have discovered a mechanism that can halt solar eruptions before they reach the Earth. This finding could improve the timing of future space missions and provide crucial insights for protecting satellites and power grids from geomagnetic storms.
Researchers develop algorithm to quantify brain map continuity, finding pathological processing reflected by discontinuity rather than signal reduction. This discovery may serve as biomarker for neurological pathologies and enable early detection of Alzheimer's disease.
A genetic mutation in the alpha-catenin 1 gene (CTNNA1) causes a butterfly-shaped pigment accumulation in the macula of the eye, leading to severe vision loss. The finding may have relevance to understanding macular degenerative diseases.
A team of researchers at Cold Spring Harbor Laboratory has devised a method to inhibit nonsense-mediated decay, a cellular process that detects errors in protein synthesis. This allows for the therapeutic restoration of protein manufacture, even when resulting proteins are truncated or partially functional.
A team from Disney Research and ETH Zurich has developed a system that can transform existing stereoscopic content into multiview content in real-time, enabling the use of glasses-less 3-D displays. The system uses image domain warping to synthesize eight new views in high definition.
A geneticist has used powerful internet and social media tools to find doctors and researchers worldwide to confirm a new X-linked intellectual disability syndrome in young boys. The syndrome is characterized by severe developmental delays, facial malformations, and generalized hypotonia, with 14 cases involving 11 unrelated families.
A study by Meredith Chivers found that heterosexual women exhibit diverse patterns of sexual response to both male and female stimuli, challenging previous assumptions about heterosexuality. The research suggests a more nuanced understanding of the relationships between sexual identity, attractions and genital responses.
Researchers find that high-energy lepton plasma flows can accelerate interstellar ions in a two-stage process, with the first stage driven by the Weibel instability and the second stage involving collisionless shock waves. This discovery has implications for our understanding of cosmic ray generation.
A review of medical literature suggests that isotretinoin therapy does not require frequent laboratory monitoring for most patients. The analysis of 26 studies found low rates of high-risk laboratory abnormalities and no significant increase in liver function or lipid levels. This finding supports less frequent lab testing, potentially...
Researchers at UMD and ARL have created a Water-in-Salt aqueous Lithium ion battery technology that doubles the voltage of current batteries without fire risk or poisonous chemicals. The new technology holds great promise for safety-critical applications, including electric vehicles and grid storage.
Researchers at Mass Eye and Ear found that chronic conductive hearing loss can lead to permanent hearing impairment if left untreated. The study, published in PLOS ONE, showed dramatic changes in the inner ear after a year of sound deprivation.
Researchers at Harvard University have demonstrated effective safeguarding mechanisms for gene drives and unveiled a method for reversing the changes they spread. This breakthrough enables the safe management of disease-transmitting organisms and paves the way for potential use in pest control and disease prevention.
The Bigelow Laboratory is part of a $8 million initiative to develop molecular tools for understanding dinoflagellates' function and their impact on ocean ecosystems. The project aims to create genetic tools that will allow researchers to investigate the activities of microbial genes and provide new capabilities for scientific inquiry.
A study found low rates of laboratory monitoring for patients with heart failure following MRA initiation, with only 7% receiving appropriate testing. Key factors associated with increased monitoring included atrial fibrillation and chronic kidney disease.
A rapid-detection Ebola test developed by Dr. Manfred Weidmann has been deployed in Senegal and Guinea, performing exceptionally well under field conditions. The test uses a method called recombinase polymerase amplification and can be stored at room temperature, operated by local teams without the need for confirmatory tests.
Scientists have made a breakthrough in understanding how the flu virus works by studying its M2 proton channel. Using advanced MRI technology, researchers gained insight into the virus's replication process, which could lead to the development of new prescription drugs.
A new study by AAAS finds that warming waters in the Gulf of Maine have contributed to the decline of New England cod stocks, despite strict quotas. The researchers used sea surface temperature data to show how ocean warming reduced cod production and led to overfishing.
Scientists developed a more general approach for controlling acoustic scattering on complex, odd-shaped objects using a coating of two thin fluid layers. The coating significantly reduces the scattering strength, allowing for ideal acoustic measurements in laboratories.
Researchers have identified the protein Panoramix, which enables cells to silence specific genes and prevent transposons from disrupting genomes. This discovery provides new insights into the innate defense mechanisms against genetic elements that can cause sterility in animals.
A national network of neurotechnology centers is proposed to accelerate the BRAIN Initiative, a decade-long scientific project with over $300 Million budget. The centers would tackle critical areas like Connectomics, Nanotechnology, and Optical Imaging, providing an alternative STEM career path for postdocs and graduate students.
Researchers aim to create ultra-high temperature materials using entropy-stabilized alloys, which can withstand temperatures of 2,000 degrees Celsius. The team will develop new experimental approaches and computational techniques to identify promising materials.
A mutation in a key enzyme affects sphingolipid levels, leading to neurodegeneration. Researchers found that increased 20-carbon sphingolipids cause problems with neuronal membranes.
Researchers from Osaka University successfully created highly unusual plasma composed of hollow atoms using ultra-bright X-ray sources. This discovery sheds light on extreme state atoms and may lead to industrial applications such as non-destructive x-ray testing and new material construction.
A recent analysis suggests that devastating ultra-rare mutations in vulnerable genes play a causal role in roughly half of all ASD cases. The study identifies 239 genes whose 'vulnerability' to such mutations makes them priority research targets.
An outbreak of Bordetella parapertussis was reported in southeastern Minnesota in 2014, with all affected children up to date on pertussis vaccines. The finding suggests that the vaccine may not protect against this lesser-known species.
SLAC's 'electron camera' visualizes ripples in 2D material for the first time, revealing atomic-level movements and guiding future device development. The breakthrough could lead to efficient solar cells, fast electronics and high-performance catalysts.
Canadians with nonspecific symptoms like joint pain and fatigue may receive false-positive results from commercial US laboratories, as many use unproven testing methods. Tests at the National Microbiology Laboratory of Canada using CDC guidelines are more accurate.
Researchers at CU-Boulder have developed a new technique for estimating sea ice concentration, improving US Navy forecasts by almost 40%. The blended input approach combines satellite data and human interpretation to capture smaller patches of sea ice, enhancing forecast accuracy.
Scientists at Cold Spring Harbor Laboratory found cholinergic neurons in the basal forebrain that rapidly inform multiple subregions of surprising rewards or punishments. These neurons enable flexibility in neuronal connections, allowing for plasticity and learning.
Krishnakumar Kizhatil has been awarded the prestigious Lewis Rudin Glaucoma Prize for his research on Schlemm's canal, a unique vessel that plays a key role in glaucoma. The prize recognizes Kizhatil's work as a major breakthrough in understanding the molecular basis of intraocular pressure elevation and its link to glaucoma.
A five-year, $9.97M grant will establish a new Center for Precision Genomics at JAX, leveraging the lab's expertise in mammalian genetics and disease modeling to develop precision models of disease. The Center will accelerate translation to medical benefit through global collaborations and shared resources.
Researchers aim to restore streams to their natural state with minimal cost and time investment. They will examine various restoration methods and sites to determine which techniques work best to achieve ecological benefits.
A $1.5 million gift will support research in spinal muscular atrophy with respiratory distress (SMARD), a rare condition affecting fewer than 70 reported cases worldwide. The funding will enable the development of effective treatments and therapies for children impacted by this devastating disease.
Charles R. Scriver is receiving the Victor A. McKusick Leadership Award from ASHG for his work in human genetics, particularly in discovering and addressing inherited metabolic diseases. He has also made significant contributions to public health through pediatric genetic screening programs and education.
An international team of scientists developed a robotic insect that can jump on water using the natural mechanics of water striders. The robot exerts up to 16 times its own body weight on the water's surface, mimicking the insects' ability to perform extreme maneuvers like jumping and flying with ease.
Researchers developed new diagnostic criteria to differentiate between malignant and benign mediastinal masses in children. The criteria use symptoms, laboratory tests, and CT scans to identify a better way to refine diagnoses, potentially leading to earlier detection of cancers like lymphomas and neuroblastomas.
Researchers found that obese adults have a heightened ability to imagine odors, particularly food and non-food smells, which may promote food cravings. This study's findings suggest the need for individualized approaches to identify factors contributing to weight gain.
A team of researchers led by UO doctoral student Kristin E. Sweeney conducted a series of experiments in small sandboxes to witness the formation of ridges and valleys in real-time. The study provides new insights into the competition between erosion driven by runoff and soil movement on hillsides, revealing how climate change may impa...
A new University of Michigan study suggests that napping may be an effective strategy to counteract impulsive behavior and boost tolerance for frustration. The study found that taking a nap increased participants' ability to persevere through difficult tasks.
A study found that most edible cannabis products sold in dispensaries carried labels with inaccurate THC levels, posing a risk to patients. The researchers called for better regulation and oversight of marijuana edibles to prevent overdosing and ensure accurate labeling.
A team of researchers has successfully developed a brain-machine interface that allows paralyzed individuals to remotely control robots with their thoughts. The technology has shown excellent results, enabling users to interact with the robot's surroundings and avoid obstacles without requiring any physical movement.
Chemists at Scripps Research Institute invent scalable method for synthesizing jiadifenolide, a plant-derived molecule with potential brain-protecting properties. The new eight-step synthesis yields gram to kilogram quantities, paving the way for further studies and development of a jiadafenolide-derived drug.
The Pew Charitable Trusts has named 10 postdoctoral scientists from Latin America to pursue research in the US with distinguished mentors. The fellows will focus on improving human health through bold approaches to biomedical research.
Researchers have developed an efficient method to deliver CRISPR/Cas9 system using electroporation, increasing genome editing speed and throughput in laboratory mice. This technique enables the creation of mouse models of human diseases with unprecedented efficiency and precision.
Researchers at Cold Spring Harbor Laboratory found that the mammalian brain uses cortical feedback to distinguish between nearly identical odors. The team tracked neural signals and found specific responses to distinct scents, suggesting a 'sparse' response and amplification of certain odors.