Articles tagged with Laboratories
The Association for Molecular Pathology released a new report highlighting the potential of MALDI-TOF-MS in identifying invasive infectious diseases. The technology has been shown to accurately identify filamentous fungi and mycobacteria, but more testing is needed before its use can be recommended.
Researchers presented advancements in Droplet Digital PCR for detecting somatic cancer mutations, including novel methods for differentiating between mutant alleles and quantifying biomarker copy numbers. Single-cell sequencing was also showcased for understanding human pluripotent stem cell population heterogeneity.
Researchers discovered a genetic link between high tryptase levels, multiple copies of the alpha tryptase gene, and a range of symptoms including dizziness, skin flushing, and gastrointestinal issues. The study provides new insights into the cause of this frustrating syndrome and potential strategies for diagnosis and treatment.
Disney Research has developed a one-legged hopper that runs on battery power, breaking its dependence on off-board power. The robot weighs less than five pounds and can maintain its balance for approximately seven seconds.
A researcher from Aalto University has created a controlled rogue wave in realistic oceanic conditions, shedding light on the phenomenon of extreme ocean waves. This breakthrough enables the design of safer ships and offshore rigs by simulating realistic rogue waves in laboratory environments.
A study found that implementing an analytic tool to allocate clinical care costs and quality measures led to significant improvements in value of care for three designated outcomes. The program resulted in reduced costs and improved quality, with notable decreases in hospitalist laboratory testing and sepsis management.
Researchers at Brigham and Women's Hospital identified a distinct gene module for T cell dysfunction, contributing to chronic disease states like cancer and chronic viral infections. A transcription factor, Gata-3, was found to play a crucial role in T cell dysfunction, offering new avenues for targeted therapy.
The J.R. Macdonald Laboratory will receive a three-year, nearly $8 million grant to support its experimental and theoretical research in atomic, molecular, and optical physics. The lab is one of the largest such programs in the country, involving over 69 researchers.
Polytechnique Montréal researchers develop nanorobotic agents that guide microscopic robots through blood vessels to deliver drugs directly to cancer cells. This breakthrough offers hope for patients with brain tumors and inoperable cancers.
Researchers at UTEP have developed a new brain preservation technique that allows for the study of brain tissue in remote locations without specialized laboratory equipment. The technique uses formaldehyde and can be performed with minimal resources, making it accessible to scientists in underdeveloped countries.
Researchers at SLAC and Stanford have created a nanostructured device that disinfects water using the full range of visible sunlight, killing bacteria in minutes. The device triggers the formation of hydrogen peroxide and other disinfecting chemicals.
New research challenges conventional wisdom on backup plans, finding they can cause people to work less hard and achieve primary goals less successfully. Researchers suggest understanding potential costs, but also encourage strategic planning to mitigate these effects.
A weakness in Linux operating systems allows attackers to track users' online activity, terminate connections, and inject false material into their communications. Researchers identified the vulnerability and have alerted Linux about it, resulting in patches applied to the latest Linux version.
CityLab will partner with Fordham University and local squash organizations to provide engaging STEM experiences for students from diverse backgrounds. The program aims to develop a national model for informal precollege biomedical science education, inspiring careers in STEM fields.
Researchers have successfully demonstrated self-organizing pattern formation in active materials at microscale by modifying one parameter. The study uses Janus colloids to experimentally test collective, dynamic behavior, creating swarms, chains, clusters, and isotropic gases.
Experts have established a common vocabulary in pharmacogenetics to advance precision medicine. The standardized terms will help guide clinicians, laboratory staff, and patients in interpreting clinical pharmacogenetic test results. The goal is to improve medication safety and effectiveness by individualizing patient care.
Empa researchers develop new flame retardants with improved flame retardancy and no toxic effects, highlighting the importance of toxicological cross-checking before mass production. The newly developed EDA-DOPO is a good candidate for further development, showing better safety and effectiveness than previously available products.
Researchers at Beth Israel Deaconess Medical Center developed a simple and versatile method using inkjet printing technology to test bacteria for susceptibility to antibiotics. The method has been shown to be accurate and reproducible, significantly decreasing the antimicrobial testing gap.
A new anonymity scheme called Riffle provides strong security guarantees while using bandwidth efficiently. The system employs a mixnet with onion encryption and uses authentication encryption to verify the authenticity of messages, ensuring cryptographically secure communication as long as one server remains uncompromised.
Dr. Diane Mathis has been awarded the FASEB Excellence in Science Award for her groundbreaking research on immunological tolerance, autoimmune diseases, and immune regulation. Her numerous publications and teaching achievements have also made a significant impact on the field of immunology.
Researchers at Jackson Laboratory aim to develop clinical adjuvants that boost vaccine effectiveness in vulnerable populations, with a focus on elderly and immunosuppressed patients. The $3.4 million grant will support the screening of new adjuvant combinations and investigation into their mechanisms of action.
The College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology announced a revised evidence-based guideline for molecular testing in lung cancer patients. The guidelines aim to improve patient selection and targeted therapies.
Scientists have found that antibodies developed in response to dengue virus can cross-react with and neutralize Zika virus, but also enhance its infection in laboratory experiments. These findings suggest a complex relationship between the two viruses and offer potential insights for vaccine design and treatment.
Researchers discovered that charge carriers in perovskites are polarons, moving coherently as one unit. This finding could help progress perovskite research projects and large-scale applications.
A team of engineers from Penn State's Applied Research Laboratory have developed an innovative approach to stabilize supercavitation bubbles, reducing the pulsation and noise that can occur during underwater vehicle movement. By applying a sinusoidal air flow variation, they were able to suppress pulsation states in many cases, allowin...
The MDI Biological Laboratory will host a lecture series on the science of aging, featuring leaders in the field who will discuss life-extending treatments and cellular recycling processes. The lectures will explore how these advances may lead to therapies that prolong healthy lifespan and address age-related diseases.
The Pew Charitable Trusts announced ten innovative postdoctoral scientists from Latin America who will receive two years of funding to pursue research at US laboratories and academic institutions. The program aims to expand frontiers in biomedical science, improving human health and well-being globally.
The Harold Alfond Foundation's charitable gift will support The Jackson Laboratory's efforts to enhance cancer diagnostics and treatment in Maine. JAX aims to provide precision cancer care using the latest genetic technologies to determine the best treatment for each patient.
Chronic fatigue syndrome (CFS) affects millions of Americans, causing profound fatigue, cognitive dysfunction, and sleep abnormalities. A new study led by Professor Derya Unutmaz aims to develop better diagnostic tools and personalized treatments for the disease.
Taxonomer analysis software rapidly identifies pathogens and profiles gene expression, revolutionizing infectious disease diagnosis. This technology can help reduce mortality rates of children in resource-limited settings by quickly detecting treatable infections.
EMBO has elected 58 outstanding scientists as new members, including Adam Antebi and George Fu Gao, in recognition of their groundbreaking research. The organization aims to support talented researchers at all stages of their careers and promote international collaboration.
Researchers develop computational model to simulate long-term effects of cardiac regenerative therapies, overcoming limitations of existing heart models. The results are consistent with some clinical study findings and will aid in optimizing therapy parameters.
Researchers have discovered a new mechanism for wound healing called wound-induced polyploidy (WIP), which maintains tissue size and function by enlarging existing cells rather than dividing new ones. This discovery has significant therapeutic potential for treating various human diseases.
Researchers discovered a unique 'hybrid' material in spider webs that maintains tautness even under stress. By mimicking this process, they created composite fibres with solid and liquid properties.
Researchers at HRL Laboratories are developing a man-portable system using high-definition transcranial current stimulation (HD-tCS) to tag specific memories and skills during learning. The STAMP method aims to improve consolidation by reactivating neural representations during sleep.
Researchers from Wake Forest University have discovered that tiger moths produce ultrasonic signals to deter bats, showing that this behavior occurs in nature and is used as a warning system. The study highlights the evolution of animal behavior in the bat vs. moth arms race.
A new parasitic wasp species, Conobregma bradpitti, has been discovered in South Africa, measuring less than 2 mm and bearing a striking resemblance to Hollywood star Brad Pitt. The species belongs to a large group of wasps that lay eggs in moth or butterfly caterpillars.
The Society for Cardiovascular Angiography and Interventions (SCAI) has released updated guidelines for cardiac catheterization laboratory (CCL) best practices. The new guidelines aim to improve the quality of care, enhance patient satisfaction, and promote consistency in cath lab operations.
Researchers at Iowa State University have created micro-scale, liquid-metal particles that can be used for heat-free soldering and metal processing without high temperatures. The discovery has significant implications for manufacturing, with potential applications in the fabrication, repair, and processing of metals.
The Maine Algal Research and Innovation Accelerator (MARIA) will be a center for developing universal algal standards, exploring new and varied ways that algae could be incorporated into products. MARIA aims to accelerate innovation in natural products created using micro and macro algae.
A new study funded by the National Institute of Allergy and Infectious Diseases proposes that co-housing laboratory mice with mice from pet stores could produce
The MDI Biological Laboratory has received a $20,000 grant from the Glenn Foundation For Medical Research to support a two-week research training course on aging biology. The course will use four animal models to study molecular pathways and explore evolutionarily conserved mechanisms of aging.
A new publication by the Association for Molecular Pathology provides cost and value analysis of gene panels, including non-small cell lung cancer and hearing loss. The study demonstrates economic value in optimizing care for patients with hereditary diseases and cancer through targeted gene panels.
Researchers have used powerful computers to analyze the decay of calcium-48, a rare isotope that could reveal the mass of neutrinos. The study suggests the decay may be half as long as previously thought, improving chances of detection in underground labs and potentially confirming Majorana particles.
ATLAS project aims to break performance and cost barriers in inertial sensors using atomic frequency reference and MEMS Coriolis Gyroscope. The goal is to achieve robust GPS-independent navigation and guidance for the US military.
Researchers are studying coral genomes to better comprehend why some reefs thrive while others die, with implications for Guam's economy and tourism industry. The new genetic sequencer will enable local scientists to tackle molecular reef ecology and train the next generation of researchers.
The Society of Interventional Radiology honored two research papers for their impact on patient care. Dong Il Gwon's study validated a rapid PARTO procedure for treating gastric varices, while Ron C. Gaba's research explored gene expression in hepatocellular carcinoma for improved treatment outcomes.
Researchers successfully replicated a range of fault slip modes found during earthquakes, quiet periods and slow earthquakes. They used ground quartz and a machine to apply pressure and alter stresses, revealing the forces behind slow earthquake mechanisms.
The EU's U_CODE Project aims to develop methods and processes for citizen involvement in large-scale construction projects, preventing conflicts and escalations. The project will create a virtual space for citizens and professional planners to exchange ideas and develop plans based on broad social consensus.
A new automated Ebola blood test has been evaluated in a field setting and shown to provide accurate results, potentially facilitating expanded access to testing. The test performed well on both whole blood and cheek swab samples, with high sensitivity and specificity.
Scientists at Scripps Research Institute (TSRI) have developed a 19-step process for synthesizing phorbol and its derivatives, providing access to powerful compounds for the development of new therapies. The method enables pharmaceutical researchers to make tiglianes in the laboratory, which are known for their biological activity and ...
An international team at the MDI Biological Laboratory is studying the role of dietary restriction in extending human lifespan. Researchers are investigating how lower amounts of food or food with lower energy content affect molecular regulators of gene expression, a key player in aging.
A new study published in the American Journal of Pathology suggests that green tea's antioxidant properties may be compromised when consumed with iron-rich foods or supplements. The researchers found that the main compound in green tea, EGCG, loses its ability to inhibit pro-inflammatory enzymes when bound to iron.
Researchers at Michigan State University have found particles of stardust, known as pre-solar grains, in meteoritic material on Earth. These grains are believed to have formed in stellar explosions billions of years ago and contain unusually high amounts of the rare isotope silicon-30.
Researchers developed Eyebrowse, a system allowing users to share self-selected aspects of their online activity with friends and the public. Users can add whitelisted sites, track friend visits, and view community browsing history, providing insights for academics and companies targeting consumers.
The American Association of Science advocates data sharing to improve transparency and reproducibility in field sciences like geology, ecology, and archaeology. Discipline-specific repositories can provide better services for researchers to access and use shared data.
A new study by Caltech researchers finds that experimental economics studies have a high replication rate of 61%, indicating that published results are reliable. The success of replication is linked to sample size and p-values, suggesting good methodological practices in the field.
A study replicated 18 experimental studies in economics, reproducing results in 11 cases and showing promise for improving replication methods. The findings suggest that clear methodological documentation is crucial for successful replications.
Researchers from the Virtual Planetary Laboratory have identified biosignature impostors, which can masquerade as signs of life on exoplanets. By detecting these 'false positive' cases, scientists can avoid misinterpreting oxygen signatures in planetary atmospheres.
Researchers from HRL Laboratories used transcranial direct current stimulation (tDCS) to improve pilot learning in a realistic flight simulator. The study found that subjects who received tDCS showed improved piloting abilities, with enhanced skill retention and faster learning rates.