Articles tagged with Laboratories
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Cold Spring Harbor Laboratory discovered a set of genes responsible for stem cell production in tomatoes, which explains the origin of the massive 'beefsteak' variety. By fine-tuning these genes, breeders can potentially customize fruit size in other crops.
A two-stage brain circuit is essential for tactile sensation, involving communication between the skin and brain. Mice were rendered unable to sense floor textures when their inner circuit was disabled, highlighting the critical role of this neural pathway in touch perception.
Researchers at the University of Iowa found no benefit from bone marrow transplantation in mice models of Rett syndrome, contradicting earlier findings. The study suggests that the initial results were due to factors other than those considered in the new experiment.
Scientists developed modified IL-2 molecules that can boost or block immune responses depending on the therapeutic application. These new forms of IL-2 have shown promising results in laboratory studies, including prolonged survival in a mouse model of graft-versus-host disease.
A new genomics laboratory in Liberia enables fast tracking of Ebola virus changes, which could impact diagnostics and therapeutics. The lab provides critical viral genomic information to support public health efforts.
Cedars-Sinai gastroenterologist Mark Pimentel has developed two simple blood tests that accurately diagnose irritable bowel syndrome (IBS) in millions of people worldwide. The new blood tests identify specific antibodies reacting to toxins from bacteria, such as salmonella, and confirm IBS diagnosis with greater than 90% certainty.
A Dartmouth study found that playing a role-playing game called RePlay Health can shift attitudes towards public health issues, with players becoming more accepting and understanding of personal behaviors and health care costs.
A new study published in Nature Communications reveals a strong connection between high ozone days in the western US during late spring and La Niña events. This connection can be used to forecast ozone levels several months in advance, improving public education and air quality management in these regions.
A new device developed by French researchers can efficiently collect bed bugs without damaging them. The modified Dyson hand vacuum is effective in collecting adults, larvae, and eggs, and has the potential to increase monitoring and control levels of this pest insect.
A new device has been developed that can detect the presence of chikungunya virus in mosquitoes within an hour, revolutionizing the field of public health. This fast and easy-to-use test has the potential to save lives by enabling swift detection and control of disease outbreaks.
Physicists at Ludwig-Maximilians-Universität München have developed a new Ytterbium:Yttrium-Aluminium-Garnet (Yb:YAG) disk laser, which produces pulses lasting 7.7 femtoseconds and enables the study of ultrafast physical processes on attosecond timescales.
Scientists studying the Northern clingfish are exploring its unique ability to generate massive suction power in wet environments. This could lead to the development of bio-inspired medical devices, such as laparoscopic surgery tools, and non-invasive whale tagging systems.
Research found habitual gamblers exhibit probability matching behavior and perceive illusory patterns in random sequences. Gamblers are also less able to resist impulses, leading to impulsive betting decisions.
The University of Oklahoma and Nanowave Technologies will establish a research group to develop next-generation electromagnetic sensors. The collaboration aims to optimize hardware solutions for customers in the airborne weather radar and satellite communications markets.
The BMC protocol provides a set of predetermined guidelines for processing and preserving forensic evidence in surgical specimens after a terrorist attack. Key findings include the importance of identifying a team to handle all surgical specimens, obtaining labeled photographs and x-rays, and storing forensic evidence securely.
At American University, chemistry majors take charge of their research projects, allowing them to develop skills in problem-solving, critical thinking, and self-motivation. The program's success has led to improved student engagement and satisfaction, with some students publishing research articles and receiving grants.
Researchers at Queen's University Belfast created a unique perfume system that releases more of its aroma when it comes into contact with moisture, resulting in a better smell. The innovative system also removes the bad odors associated with sweat by attracting and neutralizing thiol compounds.
Researchers discovered a genetic mutation causing a child's immune system dysfunction, leading to severe influenza. The study suggests that interferon amplification dependent on IRF7 expression is needed for protection against the virus.
The International Human Frontier Science Program Organization has awarded eight young researchers with a total of $300,000 over three years to establish their independent laboratories. The awardees will support training in cutting-edge, interdisciplinary research focused on the life sciences.
Patients undergoing cardiac surgery may experience excessive bloodletting due to frequent lab tests, increasing the risk of hospital-acquired anemia. Reducing preoperative bloodletting is crucial to minimize complications during surgery.
A new study suggests that bicarbonate modifies the visual signal generated by rod and cone photoreceptors, leading to improved tracking of moving objects while slightly reducing sensitivity to light. The researchers hope to explore the potential of controlling bicarbonate levels in the eye to slow or prevent eye diseases.
Scientists have discovered iron-oxidizing bacteria living near sulfur-rich black-smoker hydrothermal vents along the Mid-Atlantic Ridge. These unique chemosynthetic communities utilize iron as an energy source and are highly evolved to thrive in environments with abundant iron.
Researchers have determined the basic structural organization of the dynein-dynactin complex, a molecular motor responsible for cellular activities such as cell division and intracellular transport. The findings shed light on diseases like Alzheimer's, Parkinson's, and ALS, and could lead to new treatments.
New Northwestern University research suggests that real-world creativity may be associated with a reduced ability to filter 'irrelevant' sensory information. This 'leaky' sensory gating allows individuals to integrate ideas outside of focus, leading to creative achievements.
Alyson Santoro's research focuses on understanding archaea, essential components of nutrient cycles in the ocean. She aims to uncover how these microorganisms affect the earth's climate by studying areas with low oxygen zones. Her work has the potential to make substantial contributions to marine microbiology.
Researchers at Cold Spring Harbor Laboratory successfully decoded how rats learned to associate specific sounds with rewards, revealing the neural mechanisms underlying auditory learning. The study provides a key insight into how memories are encoded in the brain and may have implications for understanding other sensory systems.
A new study by PETA found a staggering 73% increase in the number of animals used in US laboratories between 1997 and 2012, despite industry claims of reduced animal use. Mice usage accounted for a 72.7% increase due to genetic modification experiments.
A suite of globally harmonized test methods is needed to measure a wider selection of toxicants in cigarette smoke. The International Organization for Standardization (ISO) must coordinate these methods to ensure reproducible and comparable results.
The Journal of Molecular Diagnostics published a Special Article on laboratory perspective of incidental findings reporting, highlighting the need for increased understanding and transparency of complex genomic testing. The AMP Incidental Findings Working Group recommends laboratories establish clear policies for delivering ancillary i...
A team of researchers at the University of Wyoming found that adding capsaicin from chili peppers to a diet can stimulate energy metabolism and burn stored fat, potentially preventing obesity. The study used mice on high-fat diets and found that dietary capsaicin increased metabolic activity and energy expenditure.
Pablo Tarazaga, a Virginia Tech engineer, has developed a novel approach to manipulate wave propagation in solid materials, enabling the creation of smart structures with diverse capabilities. His work holds promise for improving aircraft aerodynamics performance and creating controlled fluid-structure interactions.
Researchers at Cold Spring Harbor Laboratory have discovered a new quality control mechanism where RNAs proofread themselves, ensuring proteins are made correctly. The CCA-adding enzyme uses a screw-like motion to add CCA groups to tRNAs, and the RNA itself determines whether to allow further additions.
Researchers have developed a method to restore Survival of Motor Neuron (SMN) production only in peripheral tissues, allowing them to define the role of the drug both inside and outside of the CNS. The treatment effectively cured mice with spinal muscular atrophy, challenging assumptions about the pathology of the disease.
Researchers have developed a new model system to grow both normal and cancerous pancreatic cells in the laboratory, offering a powerful tool in the fight against pancreatic cancer. The 3D culture system, known as an organoid, can be grown from human patient tissue, providing a path to personalized treatment approaches.
Brown University professors Joseph Hogan and Rami Kantor will use a new $3.5 million grant to develop data-driven methods for improving HIV treatment monitoring decisions, potentially reducing costs and increasing effectiveness in low- and middle-income countries.
Scientists have developed a technique to coat metallic objects with an extremely thin layer of semiconductor, producing vibrant optical effects on paper and other flexible materials. The ultrathin coatings can produce bright, solid colors using the same two metals, applied with only a few atoms' difference in thickness.
Researchers at Scripps Research Institute and UC San Diego create microfluidic device to rapidly heat and cool biomolecules, allowing for the observation of rapid folding events. This breakthrough enables the study of normal and abnormal biomolecules, including those implicated in human diseases.
A Pitt study published in the American Journal of Political Science found that women are more 'election averse' than men, volunteering to lead groups but less likely to compete in elections. Women's lower willingness to run for office is attributed to factors such as election costs and the potential for negative campaigns.
A JAX research team discovered a link between mistranslation during protein synthesis and misfolded proteins in the heart, contributing to cardiac diseases like desmin-related cardiomyopathy and systemic amyloidosis. Mistranslation can lead to cell death and impaired heart function.
The UK's National Physical Laboratory and the University of Manchester are collaborating to speed up the application of graphene, accelerating its commercialization through accurate metrology and characterisation. This partnership aims to establish a Joint Centre of Excellence and make the UK a leading authority on graphene standards.
Researchers at EPFL successfully recreated the ghost illusion in the laboratory by altering sensorimotor brain signals. This phenomenon is common to many cultures and can be observed in people with neurological or psychiatric disorders, such as epilepsy.
A new mouse model reveals that genetic factors play a significant role in the severity of Ebola disease. Research suggests that certain genetic lines of mice are more resistant to the virus, while others are highly susceptible to severe illness and death. The findings could lead to rapid development of candidate therapeutics and vaccines.
Poorly executed nanosafety experiments have led to a lack of new knowledge, with most projects being irreproducible due to inadequate particle characterization. The 'NanoScreen' programme aims to address this issue by providing pre-validated methods for lab experiments using standardized test materials.
Researchers found that de novo mutations, including missense and likely gene-disrupting mutations, contribute significantly to autism. The study also identified recurrent gene-disrupting mutations in 27 genes as causal factors in severe cases.
Researchers improved plasma performance by applying lithium coatings, but the mechanism behind this improvement remains unclear. A new laboratory experiment found that temperature affects lithium's ability to retain deuterium particles, with oxygen exposure improving retention at lower temperatures.
Researchers at General Electric and Princeton Plasma Physics Laboratory have collaborated on designing a plasma-based power switch, which could contribute to the US power grid's advancement and reliability. The switch utilizes a compact, low-cost design, potentially reducing utility bills and enhancing grid efficiency.
A recent study found that searching health service pricing websites before receiving care resulted in lower claim payments for clinical services such as laboratory tests and advanced imaging. The study included medical claims from 2010-2013 of over 502,000 patients who used a price transparency platform to find prices.
A study recommends ongoing assessment of offshore wind farm impacts on marine species, particularly sound emissions and behavioral responses. The researchers suggest targeted data collection to inform regulatory decisions, minimizing negative environmental impacts.
Researchers at NYU Langone Medical Center are working on a five-year contract to discover fundamental immunology, microbial genetics, and protein structure of Staphylococcus aureus. The goal is to identify Sa antigens that are crucial for effective immune defenses.
Researchers will develop the KnowEnG tool, integrating multiple analytical methods for intuitive genome-wide data analysis. The center aims to create a powerful computational tool that offers new functional insights for genes being studied.
Cold Spring Harbor Laboratory scientists discovered that rats and mice exhibit comparable cognitive abilities, particularly in adaptive decision-making tasks. The study's findings suggest that genetic tools for mice could accelerate research on complex behaviors and learning.
Researchers advocate for massive online laboratories to prevent errors and fraud in life sciences research. These online labs use videogames to engage non-professional investigators and promote transparency, reducing the risk of scientific fraud and cherry-picking.
Scientists from China and the US report results from the first stage of the PandaX-I experiment, a dark matter search in an underground lab. The data from this experiment place strong constraints on previously reported dark matter-like signals.
Four CSHL scientists will conduct research in the Brain Research through Advancing Innovative Neurotechnologies Initiative, aiming to map the human brain and understand brain disorders. The initiative seeks to develop transformative tools for studying the brain's structure and function.
Researchers identified a compound called dequalinium chloride (DECA) that can prevent a metabolic enzyme from going to the wrong location within a cell. This prevents primary hyperoxaluria 1 (PH1), a rare and deadly genetic kidney disease, by ensuring the enzyme goes to its proper destination.
Researchers confirmed earlier findings of verbal overshadowing, where witnesses' descriptions impair their ability to select a suspect. The study found smaller effects in replications, suggesting sample sizes may have been too small to detect the effect reliably.
Scientists at Cold Spring Harbor Laboratory identified a brain region in rats responsible for their confidence in decisions. The study used rats to test decision-making and found that a specific region of the orbitofrontal cortex plays a crucial role in measuring confidence.
A comprehensive study led by Mayo Clinic in 12 countries validates the accuracy of RNA genomic sequencing techniques and laboratories. The research establishes best practices for laboratories to ensure reproducible results, enabling clinicians to make informed decisions based on genomic data.
Researchers at Nova Southeastern University will investigate biological indicators in men with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The four-year study aims to develop more effective treatment plans using existing drugs.
Researchers at SLAC National Accelerator Laboratory have created a molecule that conducts electricity in one direction, paving the way for shrinking chip components down to the size of molecules. The hybrid molecule, known as buckydiamondoid, was made by combining carbon spheres (buckyballs) with tiny diamond cages (diamondoids).