Articles tagged with Laboratories
Researchers developed an all-natural foliar spray that enhances plants' innate 'anti-freeze' properties, reducing cold damage and mortality by up to 1 USDA hardiness zone. The non-toxic spray is friendly to both plants and the environment.
A team of scientists at Cold Spring Harbor Laboratory discovered that hydrogen sulfide regulates a signaling pathway implicated in biological malfunctions. H2S modifies an enzyme called PTP1B, preventing it from inactivating PERK, a sensor of unfolded proteins and a critical regulator of cell response to ER stress.
A team of researchers performed new 3-D calculations to better understand the complex conditions driving Type Ia supernovae. The simulations provide insight into the deflagration-to-detonation transition process, which is crucial for calculating cosmic distances and understanding the evolution of the universe.
A multidisciplinary team of researchers has developed the world's lightest material, boasting a density of 0.9 mg/cc and unparalleled mechanical behavior. The novel material's unique micro-lattice cellular architecture enables complete recovery from compression exceeding 50 percent strain and extraordinary high energy absorption.
Researchers at the Princeton Plasma Physics Laboratory have created a video simulation showcasing the complex dynamics of a plasma pulse within an experimental fusion machine, offering new insights into particle confinement and magnetic field manipulation. The simulation provides a detailed 3D picture of the plasma, allowing researcher...
Researchers at the University of Canterbury developed a new method to generate extra-long electrical arcs using exploding copper wires, reducing the amount of voltage needed by more than 95%. The technique has potential applications in inducing real lightning from thunderclouds and creating novel electrical machines.
Researchers activated a gene called PGC-1, which increases mitochondrial activity, and found it significantly extends the lifespan of fruit flies' digestive tracts. The study's implications for human aging suggest targeting the intestine as a vital tissue type for healthy aging.
University of Alberta researchers create a miniature model of oil-trapping rock layers using core samples from drilling sites. The 'reservoir on a chip' model helps energy companies determine optimal water and chemical concentrations for maximum oil recovery.
Researchers used genetically modified mice with human-like enzymes to assess the health risks of food mutagens from well-done meat and fish. The results showed a significant increase in intestinal tumors after consuming substances from meat crust, highlighting the need for better models to predict human health effects.
The Alberta Diabetes Atlas provides critical data on laboratory tests for effective diabetes management, enabling healthcare providers to make informed decisions. The atlas also helps identify disparities and improve care quality across regions and communities.
Researchers isolated 63 unique dust particles from their laboratory using a new sensor technology. The study aims to aid in understanding respiratory diseases caused by airborne particles. The dust particles contained organic matter, quartz, and man-made chemicals.
Scientists at CSHL have discovered that a 27-gene cluster deletion on chromosome 16 causes autism-like features. Mouse models revealed that inheriting fewer copies of these genes leads to behaviors and brain alterations characteristic of autism.
Researchers at NTNU's Kavli Institute for Systems Neuroscience discovered that memory is divided into discrete packets, with each packet lasting around 125 milliseconds. The brain switches between these packets rapidly, allowing it to 'flip' between different maps of location and experience.
Research reveals that stronger motivation leads to increased connectivity between brain regions regulating motivation and motor learning. Rehabilitative training advances motor function recovery by activating the brain's motivation centers.
A study by CSHL and USC researchers reveals that methylation patterns are dynamic and can influence cell fate. The team observed that subtle changes in methylation within specific regions can lead to the activation of genes associated with particular cell types, challenging traditional views on epigenetics.
Researchers at UC Riverside discovered that stacking three layers of graphene creates a 'knob' for tuning its electrical properties. The team found that some trilayer graphene devices were conducting while others were insulating, depending on the layer order.
ELIXIR will provide sustainable infrastructure for managing biological information in Europe, securing public access to genes, proteins, and complex networks. The initiative aims to support life science research and its translation to medicine and the environment.
The role of clinical microbiology laboratories is evolving with the increasing availability of sophisticated technologies, which can improve the quality and delivery of services. The tools and changes they bring can substantially enhance patient care by reducing mortality rates from sepsis.
Scientists have created a new class of materials that exhibit both magnetic and superconducting properties, revolutionizing the field of electronics. By sandwiching two nonmagnetic insulators together, researchers discovered a material where the interface between the two has both magnetic and superconducting regions.
The Minimum Information about a Bioactive Entity (MIABE) standard aims to capture more information about bioactive compounds, enabling better analysis and design. By adopting this standard, researchers can analyze large datasets from various drug discovery programs, leading to improved understanding of successful drugs.
Researchers have found that Parkin, a protein linked to early-onset Parkinson's disease, regulates how cells take up and process dietary fats. This discovery suggests that defective Parkin may contribute to the development of some cases by changing fat levels in the body.
USDA scientists have developed a new biorefinery yeast that can ferment plant sugars into cellulosic ethanol despite the presence of toxic compounds. The yeast, Saccharomyces cerevisiae strain NRRL Y-50049, has shown remarkable tolerance to furfural and HMF, two compounds that inhibit yeast growth and reduce ethanol yields.
Researchers discovered striking similarities in gene expression patterns between healthy aging and neurodegenerative diseases, including Alzheimer's. Aging-related changes were found in individuals as young as 50, contradicting previous expectations.
Engineered from muscle and nerve cells, the functional anal sphincters showed normal tissue function and developed a blood supply when implanted in mice. This breakthrough suggests a potential future treatment for both fecal and urinary incontinence.
A new microfluidic-based diagnostic device, mChip, can perform complex laboratory assays and diagnose infectious diseases like HIV and syphilis in remote regions with a tiny finger prick of blood. The device significantly reduces testing time and cost, providing immediate results for medical workers.
Researchers have developed a way to help growers reduce fumigant emissions by testing the permeability of dozens of films used to cover treated soil. They found that some films are better barriers to fumigant diffusion than others, but their effectiveness varies depending on the fumigant and weather conditions.
The Collaborative Cross mouse strains have been used to map causative loci for complex traits like body weight and white head-spotting, showcasing the power of ancestry-based approaches. The studies also revealed the scope of phenotypic variation present in the CC lines, providing insights into breeding effects on genetic structure.
The University of California, Davis has signed an exclusive license agreement with Barobo, Inc. to commercialize the iMobot modular robot technology. The technology enables flexible and adaptable robots that can be reconfigured for various applications.
Researchers at TGen present two key studies on the role of genes and proteins in therapeutic treatments for lung cancer. The studies suggest that combination drug therapy may be necessary to combat non-small cell lung cancer, particularly when patients have elevated levels of a protein called JAK2.
Xuemei Chen, a leading plant scientist at UC Riverside, has been awarded an HHMI-GBMF Investigator grant for her groundbreaking research on small RNA and microRNA. The grant will support high-risk projects aimed at uncovering fundamental mechanisms in biology with potential applications to agriculture and medicine.
The Pew Charitable Trusts has named 10 outstanding early-career Latin-American scientists as Pew Fellows in the Biomedical Sciences. The program provides $60,000 in salary support and additional funding to establish research laboratories in their home countries.
Researchers developed an artificial graphene device that simulates the quantum behavior of strongly interacting electrons. The device replicates the honeycomb lattice of graphene and enables exploration of fundamental quantum physics.
A new online tool, Mouse Phylogeny Viewer, allows researchers to select from 162 strains of laboratory mice for which the entire genome has been characterized. This tool enables scientists to design better experiments by selecting strains with greater genetic diversity, ultimately improving the translation of results to humans.
Researchers have created a genome-wide map of most inbred mouse strains, finding that they represent only limited genetic diversity. The team hopes to expand this diversity by adding wild mouse populations, which could lead to more effective translation of experimental results to humans.
Researchers found that preharvest rainfall and firm fruit are key factors contributing to blueberry splitting. The study also showed that some cultivars, like 'Premier,' have a lower incidence of splitting than others, such as widely grown 'Tifblue.'
Researchers have developed autonomous robots that can explore and map buildings using a combination of navigation technology, vision-based techniques, and network technology. The robots can transmit detailed floor maps to humans in minutes, which could improve response times to emergencies and enhance safety in confined spaces.
A Northwestern University study finds that lifelong musical training can benefit adults by offsetting age-related decline in memory and ability to hear speech in noisy environments. Musicians aged 45-65 outperform non-musicians in auditory memory, hearing speech in noise, and other cognitive functions.
A prediction model that includes data on measures of several routinely obtained laboratory tests accurately predicted the short-term risk of kidney failure for patients with moderate to severe chronic kidney disease. The researchers used demographic, clinical, and laboratory data from over 7,000 patients with CKD stages 3 to 5.
Researchers harness the power of fast-replicating bacterial viruses to evolve biomolecules in the laboratory, generating enzymes with desired properties in just weeks. The phage-assisted continuous evolution approach allows for rapid generation of proteins and nucleic acids with tailored properties.
Dr. Michael S. Watson, PhD, FACMG, receives the first ACMG Presidents' Award for his groundbreaking work in translating genetic information into healthcare use. He has been a driving force behind the American College of Medical Genetics' success.
Researchers at WashU Medicine successfully grew and manipulated human intestinal microbes, identifying new probiotics and exploring microbe transplants as a treatment for obesity and diseases. The study provides a pipeline for manipulating diverse microbial communities from people of different ages and cultures.
Researchers at NIST and Virginia Tech developed a new reference material for volatile organic compounds (VOCs), which showed more accurate measurement results than previous methods. The tool aims to reduce inter-laboratory variability in VOC emissions testing, leading to improved indoor air quality and occupant health.
Jeannette Wing, a renowned computer scientist, will receive the 2011 Distinguished Service Award of the Computer Research Association. Her ideas have helped shape conceptions of what computer science is and can be, with a focus on computational thinking. The CRA cited her extraordinary performance in research, education, and service.
The Khalaf Al Habtoor Harvard Research Fellowship offers a postdoctoral researcher from the UAE or Middle East region a chance to work at Harvard Medical School for up to three years. The fellowship aims to explore fundamental scientific questions and contribute knowledge to the host laboratory.
Caltech graduate student Guoan Zheng received the 2011 Lemelson-MIT Caltech Student Prize for his on-chip microscopy imaging technology with potential applications in malaria and blood-borne diseases. Meanwhile, Wendian Shi's portable lab-on-a-chip system for determining white blood cell counts won a $10,000 award.
New York University physicists have developed a method for packing microscopic spheres that can improve various commercial products, such as pharmaceutical lotions and ice cream. The researchers manipulated the properties of emulsions using statistical mechanics and depletion attraction to create materials with desired properties.
Stevens researchers create reliable nano-actuators that can benefit diverse applications, including biomaterials and nano robots. The precise arrangement of nanowires is crucial for practical applications, but current techniques face limitations.
Researchers have discovered a promising new treatment for prion diseases, a group of untreatable brain disorders. The compound, derived from aminothiazoles, has shown to reduce abnormal prion protein in laboratory mice and cell cultures.
Researchers found that whole blood retains its clotting properties at least 11 days under standard refrigeration, potentially improving survival in war injuries and disasters. This discovery could lead to a change in clinical practice and improve the availability of whole blood for specific situations.
Researchers at Georgia Institute of Technology discovered a unique chemical signaling system in tropical seaweed that may provide new pharmaceutical compounds for treating malaria. The team found concentrated antifungal molecules at specific locations on the seaweed surfaces, which could be used to develop effective treatments.
Researchers recreated ancient Egyptian artificial toes and tested them on volunteers, finding they could help with walking. The toes date from before 600BC, predating the Roman Capula Leg as the earliest known practical prosthesis.
Researchers have discovered Largazole's potential to stimulate bone growth and repair damaged bones. The compound blocks the body's natural bone resorption process, offering new hope for treating bone diseases.
Researchers have created a new framework for analyzing key genetic variations that were previously overlooked. The study analyzed the genomes of 185 individuals and identified 22,025 deletions and 6,000 other structural variants.
A new study has identified the precise steps in the molecular evolution of Streptococcus pneumoniae, a major threat to global health. The research reveals that the bacterium's genetic makeup has undergone significant changes, with a likely birthplace in Europe and widespread spread across the globe.
The February issue of Cold Spring Harbor Protocols features a method for quantitative proteomic profiling using laser capture microdissection and nanoscale liquid chromatography/tandem mass spectrometry. Immunoimaging is also explored, with methods for studying immune system dynamics using two-photon microscopy.
A Jackson Laboratory research team has identified a mutation in a gene essential for correct protein-processing, which disrupts cellular development and growth. The study found that defects in the chaperone proteins lead to photoreceptor degeneration, central nervous system abnormalities, and male infertility.
Researchers at Iowa State University are developing biorenewable polymers capable of healing themselves as they degrade and crack. The technology embeds catalysts and microcapsules containing a liquid healing agent within a composite, releasing the agent to form 3-D polymer chains that fill cracks.
Researchers at Cold Spring Harbor Laboratory have made a breakthrough in understanding how neural circuits self-assemble. By observing the formation of inhibitory synapses, they found that GABA transmission regulates synaptic adhesion. The discovery sheds light on neurodevelopmental disorders such as autism and schizophrenia.
Researchers have identified new yeast genes that improve ethanol tolerance, allowing for higher ethanol concentrations in biofuel production. This breakthrough could make cellulosic ethanol economically competitive with fossil fuels.
A recent study published in HortScience found that Bounce fabric softener sheets can repel adult gnats, with a mean proportion of fungus gnat adults collected being significantly lower in sample compartments containing dryer sheets. The study attributed the effect to volatile compounds such as linalool and beta-citronellol.