Articles tagged with Laboratories
Researchers have created a new framework for analyzing key genetic variations that were previously overlooked. The study analyzed the genomes of 185 individuals and identified 22,025 deletions and 6,000 other structural variants.
Researchers have discovered Largazole's potential to stimulate bone growth and repair damaged bones. The compound blocks the body's natural bone resorption process, offering new hope for treating bone diseases.
A new study has identified the precise steps in the molecular evolution of Streptococcus pneumoniae, a major threat to global health. The research reveals that the bacterium's genetic makeup has undergone significant changes, with a likely birthplace in Europe and widespread spread across the globe.
The February issue of Cold Spring Harbor Protocols features a method for quantitative proteomic profiling using laser capture microdissection and nanoscale liquid chromatography/tandem mass spectrometry. Immunoimaging is also explored, with methods for studying immune system dynamics using two-photon microscopy.
A Jackson Laboratory research team has identified a mutation in a gene essential for correct protein-processing, which disrupts cellular development and growth. The study found that defects in the chaperone proteins lead to photoreceptor degeneration, central nervous system abnormalities, and male infertility.
Researchers at Iowa State University are developing biorenewable polymers capable of healing themselves as they degrade and crack. The technology embeds catalysts and microcapsules containing a liquid healing agent within a composite, releasing the agent to form 3-D polymer chains that fill cracks.
Researchers at Cold Spring Harbor Laboratory have made a breakthrough in understanding how neural circuits self-assemble. By observing the formation of inhibitory synapses, they found that GABA transmission regulates synaptic adhesion. The discovery sheds light on neurodevelopmental disorders such as autism and schizophrenia.
Researchers have identified new yeast genes that improve ethanol tolerance, allowing for higher ethanol concentrations in biofuel production. This breakthrough could make cellulosic ethanol economically competitive with fossil fuels.
A recent study published in HortScience found that Bounce fabric softener sheets can repel adult gnats, with a mean proportion of fungus gnat adults collected being significantly lower in sample compartments containing dryer sheets. The study attributed the effect to volatile compounds such as linalool and beta-citronellol.
Researchers at the University of Toronto have identified a spontaneously chain-reacting molecule that can grow durable 'molecular-chains' on surfaces. This discovery could enable faster and more efficient creation of nano-wires for circuitry applications.
Researchers at Caltech, with support from the Air Force Office of Scientific Research, have found that flies follow horizontal edges to regulate altitude, unlike earlier studies suggesting they measure motion beneath them. This edge-following behavior is similar to their steering mechanism and relies heavily on vision.
Researchers from Arizona State University have discovered a calcium-driven pump mechanism in endolithic cyanobacteria, which dissolves carbonate substrates. This finding has implications for coral reefs and mussel aquaculture, addressing a long-standing geochemical paradox.
Purdue University researchers are studying the effects of fire on steel structures using a one-of-a-kind heating system. The testing focuses on how building components behave in extreme temperatures, with results comparing computational models to real-world experiments.
Duke University Medical Center will oversee external quality assurance programs for HIV laboratories worldwide, ensuring reliable and reproducible data for treatments, under a $52.8 million NIH contract. The project aims to address global laboratory standards, tracking virus strains and assays for new therapies.
A study found that playing Tetris after viewing traumatic images reduced memory flashbacks in healthy volunteers. However, playing a word-based quiz game increased flashbacks. The researchers suggest that Tetris competes with the brain's perceptual information channel, reducing traumatic memories.
Dr. Hongbin Li receives a three-year AFRL contract to study distributed radar systems and improve object detection, developing networked radar capabilities with high spatial resolution and accuracy. The goal is to combine software and hardware for efficient data communication and achieve better bandwidth from multiple radar sensors.
The Central Appalachians Stable Isotope Facility (CASIF) was established to study environmental changes using stable isotopes. Researchers now have access to a state-of-the-art instrument for analyzing materials such as water, pollen, and soils.
The article reviews standard and cutting-edge laboratory techniques for three-dimensional biological imaging, including confocal microscopy and array tomography. These methods allow for the visualization of previously inaccessible features of tissue structure and molecular architecture.
The University of Houston is developing new technologies for the alternative energy industry with a $1.2 million grant from the Office of Naval Research. Researchers will focus on improving thin-film solar cell efficiency and developing nanosensors for wind turbine blades to monitor structural health.
A team of scientists from Caltech and JPL have characterized a key chemical reaction affecting smog formation, suggesting current models underestimate ozone levels by 5-10%. Their findings likely impact air quality predictions, emissions regulation, and health assessments.
UK scientists at NPL create standards for measuring electric materials on the nanoscale, allowing for more accurate devices and a better understanding of nanotechnology's role in electric materials. This breakthrough enables comparisons to be made and promotes the development of new nano-structured ferroelectric materials.
The Journal of Molecular Diagnostics is published on behalf of the Association for Molecular Pathology (AMP) and the American Society for Investigative Pathology (ASIP). The journal publishes high-quality original papers on scientific advances in molecular diagnostics.
A consensus statement from The Endocrine Society and the US Centers for Disease Control and Prevention calls for improved testosterone testing standards. The recommendations aim to increase accuracy, reliability, and comparability of measurements over time.
Researchers found that power users prefer customization to control their information universe, while nonpower users prefer personalized experiences with assured privacy. This study highlights the importance of considering user experience and privacy concerns when designing online news platforms.
The University of Maryland Center for Environmental Science's Chesapeake Biological Laboratory is rebuilding its historic research pier after receiving a $1.7 million National Science Foundation grant. The pier, which has played a crucial role in climate change and fisheries management research since 1936, sustained major damage from r...
Researchers at Fraunhofer Institute have developed new detection equipment that can reliably identify liquid explosives. The method involves sensors detecting vapors from open containers or x-ray equipment scanning unopened bottles, paving the way for lifting of EU ban on carry-on liquids.
The completed cacao genome project provides genetic information to improve planting stocks and protect fragile incomes of West African, Asian, and South American cocoa farmers. The dataset is publicly available, enabling breeders and researchers around the world to share tools and fight disease in their crops.
Scientists at University of East Anglia and Frankfurt discover largest chlorine isotope enrichment ever found in nature. This breakthrough could lead to identification of sources of banned CFCs still being released into the atmosphere.
Researchers at the University of New Hampshire have created a novel method using power meters and stationary bicycles to determine cycling fitness. The technique allows athletes to establish personalized training zones with high accuracy, enabling coaches to prescribe targeted workouts.
A large population study found a statistically significant association between BPA exposure and increased testosterone levels in men. The study, which analyzed data from over 700 adults aged 20-74 years, suggests that even low-level exposure to BPA may have endocrine-disrupting effects on human health.
Researchers developed novel antisense therapies that protected monkeys infected with deadly Ebola or Marburg viruses, with survival rates over 90%. The treatments were administered up to one hour after exposure and showed promise for treating accidental infections in laboratory or hospital settings.
Researchers at Purdue University have developed a new technology enabling tiny machines to self-calibrate, leading to super-accurate sensors for crime scene forensics, environmental testing and medical diagnostics. This innovation could revolutionize fields like tracking criminal suspects and detecting hazardous substances.
Researchers have developed electrowetting displays that offer high resolution, fast switching speeds, and low power consumption, enabling video content displays and potentially revolutionizing the industry
USDA scientists create a new sustainable potting medium called WholeTree, made from thinned pine trees. The material can replace costly and time-consuming materials like peat moss, perlite, and vermiculite, reducing energy costs and environmental impact.
Researchers at UCLA found that when one brain region is damaged, another region can take over its function. The study suggests that the brain has a mechanism to adapt and compensate, potentially leading to new treatments for patients with memory impairments.
New research on Martian rocks suggests they may hold evidence of living organisms from 4 billion years ago. The findings provide a promising lead for future exobiology missions and shed light on the potential for life on early Mars.
Mice cages alter brains in mice used in laboratories, affecting outcomes of research, according to a breakthrough study published in PLoS One. The type of cage can change the brain's olfactory bulb and levels of aggression.
Researchers at Florida Institute of Technology have developed a streamlined process for synthesizing the chemical compound CDNI-Glu, reducing production time from 150 hours to 24 hours. The licensed technology will be commercially available through Tocris, enabling neuroscientists to study brain neural networks more efficiently.
The University of Southern California has received a $56.8 million Clinical and Translational Science Award from the NIH to support real-life applications of scientific discoveries in healthcare. The Los Angeles Basin CTSI will partner with community organizations and providers to address health issues in urban environments.
Two protocols from the Neurobiology of Drosophila course are now available in Cold Spring Harbor Protocols: a method for stimulating neurons in the brain and identifying neuroblasts via immunofluorescent staining. These methods provide insight into the giant fiber system and role of stem cells in development.
Agricultural Research Service-funded scientists found that a combination of protective nutrients and low-glycemic-index diet provides an AMD protective effect. The most protective nutrients were vitamins C and E, zinc, lutein, zeaxanthin, and omega-3 fatty acids.
The new School for Global Animal Health will support scientific staff with two floors of research laboratory space and an administrative wing. The facility aims to reduce zoonotic diseases through vaccination and strategic interventions in animal populations and the environment.
Researchers examine how consumers think about money and time, finding that accounting periods affect tracking of temporal costs. The study reveals people are more likely to return to an event if they spent time on it during the same accounting period, not when spending money.
A 110-foot long, 200-ton concrete bridge model at the University of Nevada, Reno withstood a powerful earthquake simulation three times more intense than the 1994 Northridge quake. The design and components passed the test with 10 inches of deflection in support columns, remaining standing.
Researchers have found that anoxia-induced suspended animation can protect organisms from extreme cold, preserving cell-cycle control and preventing biological instability. This discovery may lead to improved techniques for extending the shelf life of human organs for transplantation.
Research reveals that increased acidity in Chesapeake Bay is reducing rates of juvenile oyster shell formation, highlighting the need for better monitoring and measurement protocols. Acidity levels vary across different regions of the Bay, with some areas becoming more acidic and others more alkaline.
A team of UMCES scientists will study the effects of the Deepwater Horizon oil spill on plankton and fish communities in the northern Gulf. They aim to shed light on the environmental consequences by comparing data from previous research cruises.
The article discusses gel electrophoresis of RNA, a widely used technique for detection, quantification, and purification. It also highlights the use of avian imaging in live imaging of fluorescently labeled cells within a living embryo, providing insight into vertebrate development.
Scientists have successfully prevented monkeys exposed to the deadly Ebola virus from dying of hemorrhagic fever using a genetic material-based treatment. The study suggests that such protection could also be possible in humans, offering new hope for combating the highly contagious and lethal disease.
Researchers at the University of Leicester have dissected comet samples to reveal their true composition, shedding light on the Solar System's early stages and water delivery. They found unexpected signs of high-temperature iron oxides, raising questions about comet formation.
The American Society for Microbiology will honor Scripps Institution of Oceanography pioneer Claude ZoBell's contributions to marine microbiology. The event, held on May 22, recognizes ZoBell's pioneering research career and his work laying the foundation for the field.
A team of paleontologists, geochemists, and physicists used X-ray technology to analyze the Thermopolis Archaeopteryx fossil, revealing half a dozen chemical elements that were part of the living animal itself. The study confirms that feathers in the fossil are actual fossilized feathers containing phosphorus and sulfur.
Scientists at TUM developed a novel biosensor chip that can detect specific proteins with high sensitivity, enabling early disease diagnosis. The chip can analyze multiple parameters, including protein concentration and alterations caused by diseases or medications.
Bionanotechnology at Florida State University has significant applications in medicine, manufacturing, and more. The institution's cutting-edge research utilizes Dip-Pen Nanolithography to create biometamaterials with potential for diagnosis and analysis.
Age-related nerve decline is associated with metabolic factors like blood sugar levels within normal ranges. Peripheral nerves are affected more in men than women later in life, suggesting a link between aging, gender, and inflammation. Modifiable risk factors may help prevent or delay peripheral nerve function decline.
The South East Asia Infectious Disease Clinical Research Network emphasizes the importance of laboratory improvement for generating reliable data in resource-constrained settings. Local experts and scientists are vital to research, requiring active participation in scientific activities and continuing education programs.
Dr. Alecia Willis, a clinical molecular geneticist, was recognized for her platform presentation on personal medical genomics at the American College of Medical Genetics Annual Clinical Genetics Meeting. The Signature Genomic Laboratories Travel Award supports rising medical genetic researchers in the field.
Researchers use tissue engineering to create healthy organs and neuronal circuits, enabling live imaging of transplanted tissues and neural activity. The protocols provide methods for monitoring tissue perfusion, cell survival, and interaction/integration, allowing for improved culturing and implantation techniques.
The American College of Medical Genetics Foundation has recognized Dr. Marilyn M. Li's efforts in advancing the field of medical genetics. She is being supported by a $100,000 grant to promote safe and effective genetic testing services.
Mariam El-Ashmawy, a UT Southwestern Medical Center student, has been awarded a $44,000 annual fellowship from the Howard Hughes Medical Institute to support her studies towards a doctoral degree in science. The Gilliam fellowships aim to increase diversity in college and university faculty members.