Articles tagged with Laboratories
Researchers from Cold Spring Harbor Laboratory present a method for targeting hematopoietic stem cells using engineered lentiviral vectors. An alternative approach using DNA transposons offers a safer and effective way for non-viral gene transfer.
Researchers Dr. Margaret Palmer and Dr. Solange Filoso caution that market-based environmental restoration programs lack scientific certainty to ensure ecosystem health improvements.
A comprehensive book Shifting Sands examines Maryland's Coastal Bays ecosystem, detailing its six subwatersheds, history, and ecology. The study synthesizes decades of research to provide a holistic understanding of the region's fragile lagoons.
Montana State University is launching a pilot program to test the effectiveness of web-based engineering laboratory courses. With an $148,000 NSF grant, students will be able to control real laboratory equipment from home computers, simulating in-person lab experiences.
Researchers from Northwestern University have successfully grown a woman's immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. This breakthrough could provide a new fertility option for women whose cancer treatments destroy their ability to reproduce.
Dr. Keri Smith has received a Career Development Award from the National Hemophilia Foundation to develop a therapy for people with Hemophilia A. Her approach involves altering chemical signals produced by T cells that trigger immune responses, making individuals more receptive to replacement Factor VIII.
A new metagenomic approach quantifies microorganisms in environmental or medical samples, while a method for adhesive micropatterning offers a simple technique for generating patterns. These methods provide insights into microbial populations and cellular behaviors.
The first comprehensive global assessment reveals accelerating losses of seagrasses, threatening the health and sustainability of coastal ecosystems. Seagrasses disappear at rates similar to coral reefs and tropical rainforests, with a loss of 110 square-kilometers per year since 1980.
Researchers found a coffee extract can prevent malodorous bacteria from causing bad breath, contradicting the common assumption that coffee leads to bad breath. The team tested different brands of coffee and found some components that inhibit bacterial odor production.
The study found that hydrofluorocarbons (HFCs) will become an increasingly larger factor in future climate warming if business-as-usual trends continue. By 2050, HFC emissions could contribute 7-12% to climate change, exceeding CO2's current contribution.
Researchers are developing effective treatment strategies and animal model systems to study the effects of explosive blast-induced traumatic brain injury. Current research aims to recreate battlefield injuries in laboratory settings to better understand head injuries sustained during combat.
The Pew Charitable Trusts has named 10 promising young scientists as Pew Latin American Fellows in the Biomedical Sciences. The fellows will receive $60,000 in salary support and an additional $35,000 to purchase essential equipment upon returning to their home countries.
Dr. Jeffrey Friedman of Rockefeller University identified leptin as the 'satiety factor' behind obesity and type 2 diabetes, shedding light on chemical and genetic factors involved in the condition. The discovery has opened possibilities for future pharmaceutical treatments, influencing research worldwide.
A new study finds nearly a doubling of illegal fishing in the Northeast multispecies groundfish fishery, with 12-24% annual harvest taken illegally. The study recommends a 'smart compliance policy' to combat noncompliance and protect fish stocks.
The article describes a new approach for targeted mutagenesis in Drosophila melanogaster using ChIP-Seq analysis. The SIRT method combines homologous recombination, site-specific integration, and bacterial recombineering to facilitate efficient genetic variants at specific loci. This novel technique enables researchers to investigate g...
Theoretical work by SLAC researchers reveals two methods for detecting true muonium's formation and decay in electron-positron accelerators. These methods use relativistic effects to create a stable signature, making observation of the exotic atom feasible. The discovery has the potential to reveal new forms of matter.
Researchers found that confined spaces lead to greater variety seeking, as people diversify their choices. In crowded stores, customers tend to choose unfamiliar and unique brands.
A recent study found that women have a more powerful innate immune system than men due to the presence of estrogen. Estrogen blocks an enzyme called Caspase-12, which prevents the inflammatory process, making women more resistant to infection.
Researchers at NIST conducted experiments on wind-driven fires in high-rise buildings, finding that conditions can quickly spread smoke, heat, and gases through hallways and stairwells. Techniques such as blocking windows with fire-resistant materials and using 'floor below nozzle' systems showed promise in reducing hazardous conditions.
The May issue of Cold Spring Harbor Protocols features a set of methods to analyze protein complexes, including Blue-Native PAGE and differential in-gel electrophoresis. Additionally, researchers can generate viral vectors using adenovirus technology for efficient gene delivery.
Jindong Chen, a VARI researcher, has been awarded the AACR Scholar-in-Training Award for his presentation on Birt-Hogg-Dubé (BHD) syndrome and its relation to kidney tumors. This award recognizes groundbreaking cancer research and is highly competitive among applicants.
Physicists at Ames Laboratory have demonstrated that the superconductivity mechanism in iron-arsenide superconductors is unique compared to all other known classes of superconductors. The team found a power-law variation of London penetration depth, suggesting electron pairing different from any other known superconductor.
Gary Borisy, MBL director and CEO, has been elected to the National Academy of Sciences for his distinguished contributions to cell biology. He is a pioneer in the field, having discovered protein tubulin and provided insights into chromosome movement, cell motility, and microtubule dynamics.
Grapevine flowers' fragrance comes from pollen grains stored in anthers, contrary to common perception that petals produce perfume. The scent serves as a defense mechanism to protect male reproductive tissues from predatory insects.
This article provides optimization strategies for polymerase chain reaction (PCR) and a method for loading individual cells with fluorescent probes via patch pipettes. The techniques are described in detail, including touchdown PCR and hot-start PCR, and their applications in neuroscience research.
Dr. Kathy M. Chun, Director of Cytogenetics and Molecular Genetics at North York General Hospital, is the recipient of the 2009 Signature Genomic Laboratories Travel Award. The award recognizes outstanding young researchers in medical genetics and covers travel costs to the ACMG meeting.
A study of 65 female commercial sex workers found that remote screening using tampon-based self-collection was easy and preferred over traditional methods. The method proved to be more accurate in detecting gonorrhoea and Chlamydia, with a higher number of cases identified compared to traditional tests.
Whitehead Institute member Peter Reddien has been awarded an Early Career Scientist position by the Howard Hughes Medical Institute (HHMI), providing him with a six-year funded research program. He will investigate regeneration in planaria flatworms, a project that aligns with HHMI's goals to support innovative and creative science.
A new measurement standard for vitamin D may lead to better bone health, particularly in children, women, and the elderly. The standard, developed by NIST and NIH, will enable more accurate and reliable vitamin D measurements in blood samples.
The renewal of the European Associated Laboratory Agreement establishes a France-Israel laboratory of neuroscience, fostering joint research projects and collaborative publications. The new agreement aims to promote brain research opportunities in Europe amidst calls for boycotting Israeli academia.
Researchers investigated coral skeleton formation and found systematic compositional variations, complicating paleoenvironmental change proxies. Meanwhile, a study on Venus' vortices revealed similarities with terrestrial hurricanes, potentially aiding atmospheric superrotation understanding.
Two new methods are featured in Cold Spring Harbor Protocols: a rapid, reversible method for studying protein stability using small molecules, and a combined technique for identifying proteins that mediate long-range chromosomal interactions. These methods provide new tools for investigating protein function and chromatin structure.
Researchers found that consumers' quality expectations were initially misled by biasing cues, but they learned from these mistakes and made more accurate judgments in subsequent purchases. The study suggests marketers should rethink their strategies for misleading consumers with false attributes, as it may backfire on repeat purchases.
Researchers found that combining DHEA with red clover isoflavones increased testosterone production and reversed androgenic effects in prostate cells. The study suggests a potential cancer prevention effect of herbal supplements like DHEA, warranting further research.
A research model has shown that training people to avoid falls by exposing them to unstable situations can help them maintain their balance on a slippery floor. The study found that trained subjects were better at controlling the landing foot and unconsciously changed their gait, reducing the risk of falling.
Researchers at UC Davis have discovered a new class of drugs that can reduce heart swelling and reverse heart failure. The study, led by cardiologist Nipavan Chiamvimonvat and entomologist Bruce Hammock, found that the enzyme soluble epoxide hydrolase plays a key role in the development of cardiac hypertrophy.
Researchers find that stretching facial skin during speech affects perceived sound, linking production and perception. The study contributes to understanding the relationship between speech perception and production.
A study led by Professor Derry Roopenian found that a blocked protein called Interleukin 21 prevents systemic lupus erythematosus (SLE) in mice. The researchers also demonstrated the importance of IL21 signaling in SLE progression, suggesting that interrupting this process could be an effective therapeutic option for human SLE patients.
Two protocols, one for DNA repair homologous recombination and another for sumoylation of proteins, are featured in CSH Protocols. These methods provide a biochemical means to dissect the mechanisms of molecular processes involved in DNA repair and post-translational modification.
The Rockefeller University Center for Clinical and Translational Science has awarded grants to university investigators to conduct early studies in translational science. These studies may lead to improvements in human health if successful.
Researchers found that most respondents reported improved mood after a good cry, but some felt worse or no improvement. Criers who received social support experienced the most significant improvements in mood. The study highlights the complexities of crying behavior and its physical and emotional effects.
WPI will support teaching and research programs in fire protection engineering with the new facility. The university is home to the world's leading graduate program in fire protection engineering.
A new study in Journal of Consumer Research uncovers a strategy for releasing consumers from 'regret lock' after missing a sale. By offering alternative sales on similar products, retailers can increase purchase likelihood and market share.
Simple clinical and laboratory tests can identify low-risk stomach bleed patients who can be safely managed as outpatients. This approach reduces hospital admissions by 71% without adverse effects on patient care.
Scientists have successfully grown two native bushy species, Genista versicolor and Reseda complicata, to suggest new mechanisms for restoring vegetation in the ski resort. The study aims to improve germination and growth percentages of these species using different vegetable growth regulators.
A balance between large research groups and individual scientists is optimal for success, according to a novel theory by Adrian Bejan. Successful research groups grow naturally and contribute to the whole, while solitary thinkers have flourished throughout history due to science being good for society.
The journal Cold Spring Harbor Protocols presents two articles detailing experimental culture methods for cells from the immune system and the nervous system. These protocols enable researchers to isolate and grow specialized cells like macrophages and cerebellar granule neurons, facilitating studies on their functions and interactions.
In a groundbreaking study, researchers have identified a common variant in the GRM7 gene as being associated with susceptibility to glutamate excitotoxicity and hearing loss. The findings could lead to treatments that bring relief to millions of people worldwide suffering from age-related hearing loss.
Biological damage caused by declining calcium levels is causing widespread transformation of aquatic food webs in boreal lakes in North America. The phenomenon, known as 'aquatic osteoporosis,' affects many lake-dwelling organisms, including water fleas, and has important management implications.
Researchers used computer modeling and experimentation to investigate how cracks grow at low speeds in silicon, finding rearrangements of atoms associated with ductile materials can occur near the crack tip. This instability can lead to macroscopic changes in the path of the crack, leaving behind ridges on the crack surface.
Emory University's new Human Health: Molecules to Mankind (M2M) program trains students in both laboratory and population sciences, aiming to create a comprehensive approach to understanding human health. The program partners researchers from schools of medicine, public health, and other institutions.
Using a novel combination of technologies, researchers identified 13 previously unknown tumor suppressor genes that, when mutated, can lead to liver cancers. These findings may provide new avenues for cancer therapy and have implications for understanding the molecular causes of the disease.
The journal features two articles with detailed instructions for setting up experimental culture systems. These methods allow researchers to study and manipulate developing cells and tissues in the laboratory, enabling the identification of neural progenitor cells and the analysis of cell migration between organs during development.
The Rutgers University Cell and DNA Repository has received two major NIH awards to support investigations into the genetics of mental disorders, metabolic diseases, and digestive health. The funds will enable researchers to study the genetic causes of complex diseases such as autism, bipolar disorder, and diabetes.
The University of Warwick is acquiring over 200 plastinated body parts from Germany for its medical school, a £400,000 investment in anatomy education. These specimens will be used by students to understand human anatomy and develop surgical skills.
Researchers have identified a stable, modifiable virus capable of withstanding harsh conditions and can be used as a nanobuilding block. The virus particles are ideal for producing materials on the nanometre scale and can be modified spatially controlled.
Researchers from Georgia Tech, University of Dayton, and others develop a stronger, more practical dry adhesive inspired by gecko feet. The new material creates directionally-varied adhesive force, with a gripping ability nearly three times that of real geckos.
Scientists will explore chemical reactions in extreme space conditions using a new research center combining laboratory experiments, theoretical studies, and radio-telescope observations. The Center for Chemistry of the Universe aims to expand our understanding of molecule formation that may seed young planets with life.
Researchers at Cold Spring Harbor Laboratory found that a splicing factor called SF2/ASF targets known cancer-related proteins, leading to the disruption of cellular processes. Understanding these complex molecular interactions may lead to new approaches for cancer treatment.
A team of researchers argues that current publication practices create an extreme imbalance between the abundance of supply and limited venues for publication, leading to unrepresentative results. This distortion affects the broader scientific community, as only a small proportion of research findings are selected for publication.